Ca2+ switches the effect of PS-containing membranes on Factor Xa from activating to inhibiting: Implications for initiation of blood coagulation

Biochemical Journal

Volumn 462, Issue 3, 2014, Pages 591-601

  Koklic, Tilen ^a,b,c   Majumder, Rinku ^a   Lentz, Barry R ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b Center of Excellence NAMASTE   (Slovenia)

^c JO EF STEFAN INSTITUTE   (Slovenia)

Author keywords

Calcium; Factor viia; Factor Xa; Phosphatidylserine; Prothrombin; Thrombin

Indexed keywords

BLOOD CLOTTING FACTOR 10A; CALCIUM ION; THROMBIN; CALCIUM; LIPOSOME; PHOSPHATIDYLSERINE;

ANTICOAGULATION; ARTICLE; BLOOD CLOTTING; CRITICALLY ILL PATIENT; DISSEMINATED INTRAVASCULAR CLOTTING; HUMAN; HYPOCALCEMIA; PRIORITY JOURNAL; PROTEIN BINDING; REGULATORY MECHANISM; THROMBOCYTOPENIA; METABOLISM; PHYSIOLOGY; PROTEIN MULTIMERIZATION;

BLOOD COAGULATION; CALCIUM; FACTOR XA; HUMANS; PHOSPHATIDYLSERINES; PROTEIN MULTIMERIZATION; UNILAMELLAR LIPOSOMES;

EID: 84907363825     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20140130     Document Type: Article

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