Cooperative roles of factor Va and phosphatidylserine-containing membranes as cofactors in prothrombin activation

Journal of Biological Chemistry

Volumn 278, Issue 8, 2003, Pages 5679-5684

  Weinreb, Gabriel E ^b   Mukhopadhyay, Kasturi ^b   Majumder, Rinku ^b   Lentz, Barry R ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CATALYSIS; ENZYMES; PROTEINS;

SEQUENTIAL MODEL;

BIOCHEMISTRY;

BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5A; CHROMOGENIC SUBSTRATE; ENZYME PRECURSOR; FLUORESCENT DYE; MEIZOTHROMBIN; PHOSPHATIDYLSERINE; PRETHROMBIN 2; PRETHROMBIN 2 PLUS FRAGMENT 1.2; PROTHROMBIN; THROMBIN INHIBITOR; UNCLASSIFIED DRUG; 1,2 OLEOYLPHOSPHATIDYLCHOLINE; 1,2-OLEOYLPHOSPHATIDYLCHOLINE; MEMBRANE LIPID; PHOSPHATIDYLCHOLINE; THROMBIN;

ARTICLE; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME KINETICS; MICHAELIS CONSTANT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; BINDING SITE; KINETICS; METABOLISM;

BINDING SITES; ENZYME ACTIVATION; ENZYME PRECURSORS; FACTOR VA; KINETICS; MEMBRANE LIPIDS; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLSERINES; PROTHROMBIN; THROMBIN;

EID: 0037458655     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M208423200     Document Type: Article

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