Significance of vitamin D receptor gene polymorphisms for risk of hepatocellular carcinoma in chronic hepatitis C

Translational Oncology

Volumn 7, Issue 4, 2014, Pages 503-507

  Hung, Chao Hung ^a   Chiu, Yi Chun ^a   Hu, Tsung Hui ^a   Chen, Chien Hung ^a   Lu, Sheng Nan ^a   Huang, Chao Min ^a   Wang, Jing Houng ^a   Lee, Chuan Mo ^a  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

RESTRICTION ENDONUCLEASE; VITAMIN D RECEPTOR;

ADULT; ARTICLE; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE SEVERITY; DNA POLYMORPHISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENOTYPE; HAPLOTYPE; HEPATITIS C; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PREVALENCE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RESTRICTION SITE; RISK FACTOR;

EID: 84907308208     PISSN: None     EISSN: 19365233     Source Type: Journal    
DOI: 10.1016/j.tranon.2014.05.001     Document Type: Article

References (36)

1. Mohd Hanafiah K, Groeger J, Flaxman AD, and Wiersma ST (2013). Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence. Hepatology 57, 1333-1342.
2. Hajarizadeh B, Grebely J, and Dore GJ (2013). Epidemiology and natural history of HCV infection. Nat Rev Gastroenterol Hepatol 10, 553-562.
3. Massard J, Ratziu V, Thabut D, Moussalli J, Lebray P, Benhamou Y, and Poynard T (2006). Natural history and predictors of disease severity in chronic hepatitis C. J Hepatol 44(1 Suppl.), S19-S24.
4. Hung CH, Lee CM, Wang JH, Hu TH, Chen CH, Lin CY, and Lu SN (2011). Impact of diabetes mellitus on incidence of hepatocellular carcinoma in chronic hepatitis C patients treated with interferon-based antiviral therapy. Int J Cancer 128, 2344-2352.
5. Yu MW and Chen CJ (1994). Hepatitis B and C viruses in the development of hepatocellular carcinoma. Crit Rev Oncol Hematol 17, 71-91.
6. Hung CH, Lee CM, Lu SN, Wang JH, Hu TH, Tung HD, Chen CH, Chen WJ, and Changchien CS (2006). Long-term effect of interferon alpha-2b plus ribavirin therapy on incidence of hepatocellular carcinoma in patients with hepatitis C virus-related cirrhosis. J Viral Hepat 13, 409-414.
7. Bataller R, North KE, and Brenner DA (2003). Genetic polymorphisms and the progression of liver fibrosis: a critical appraisal. Hepatology 37, 493-503.
8. Holick MF (2007). Vitamin D deficiency. N Engl J Med 357, 266-281.
9. Peterlik M and Cross HS (2005). Vitamin D and calcium deficits predispose for multiple chronic diseases. Eur J Clin Invest 35, 290-304.
10. Heubi JE, Hollis BW, Specker B, and Tsang RC (1989). Bone disease in chronic childhood cholestasis. I: vitamin D absorption and metabolism. Hepatology 9, 258-264.
11. Chiu KC, Chu A, Go V, and Saad MF (2004). Hypovitaminosis D is associated with insulin resistance and β-cell dysfunction. Am J Clin Nutr 79, 820-825.
12. Köstner K, Denzer N, Müller CS, Klein R, Tilgen W, and Reichrath J (2009). The relevance of vitamin D receptor (VDR) gene polymorphisms for cancer: a review of the literature. Anticancer Res 29, 3511-3536.
13. Tang C, Chen N, Wu M, Yuan H, and Du Y (2009). Fok1 polymorphism of vitamin D receptor gene contributes to breast cancer susceptibility: a metaanalysis. Breast Cancer Res Treat 117, 391-399.
14. Raimondi S, Johansson H, Maisonneuve P, and Gandini S (2009). Review and meta-analysis on vitamin D receptor polymorphisms and cancer risk. Carcinogenesis 30, 1170-1180.
15. Bai YH, Lu H, Hong D, Lin CC, Yu Z, and Chen BC (2012). Vitamin D receptor gene polymorphisms and colorectal cancer risk: a systematic metaanalysis. World J Gastroenterol 18, 1672-1679.
16. Onen IH, Ekmekci A, Eroglu M, Konac E, Yesil S, and Biri H (2008). Association of genetic polymorphisms in vitamin D receptor gene and susceptibility to sporadic prostate cancer. Exp Biol Med (Maywood) 233, 1608-1614.
17. Huang YW, Liao YT, Chen W, Chen CL, Hu JT, Liu CJ, Lai MY, Chen PJ, Chen DS, and Yang SS, et al (2010). Vitamin D receptor gene polymorphisms and distinct clinical phenotypes of hepatitis B carriers in Taiwan. Genes Immun 11, 87-93.
18. Vogel A, Strassburg CP, and Manns MP (2002). Genetic association of vitamin D receptor polymorphisms with primary biliary cirrhosis and autoimmune hepatitis. Hepatology 35, 126-131.
19. Fan L, Tu X, Zhu Y, Zhou L, Pfeiffer T, Feltens R, Stoecker W, and Zhong R (2005). Genetic association of vitamin D receptor polymorphisms with autoimmune hepatitis and primary biliary cirrhosis in the Chinese. J Gastroenterol Hepatol 20, 249-255.
20. Yao X, Zeng H, Zhang G, Zhou W, Yan Q, Dai L, and Wang X (2013). The association between the VDR gene polymorphisms and susceptibility to hepatocellular carcinoma and the clinicopathological features in subjects infected with HBV. Biomed Res Int, 953974.
21. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, and Scheuer PJ (1994). Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 19, 1513-1520.
22. Bruix J and Sherman M; American Association for the Study of LiverDiseases (2011). Management of hepatocellular carcinoma: an update. Hepatology 53, 1020-1022.
23. Springer JE, Cole DE, Rubin LA, Cauch-Dudek K, Harewood L, Evrovski J, Peltekova VD, and Heathcote EJ (2000). Vitamin D-receptor genotypes as independent genetic predictors of decreased bone mineral density in primary biliary cirrhosis. Gastroenterology 118, 145-151.
24. Nahon P and Zucman-Rossi J (2012). Single nucleotide polymorphisms and risk of hepatocellular carcinoma in cirrhosis. J Hepatol 57, 663-674.
25. Liu Y, Gao SJ, Du BX, and Wang JJ (2014). Association of IL-6 polymorphisms with hepatocellular carcinoma risk: evidences from a meta-analysis. Tumour Biol 35, 3551-3361.
26. Liu K, Zhang L, Lin X, Chen L, Shi H, Magaye R, Zou B, and Zhao J (2013). Association of GST genetic polymorphisms with the susceptibility to hepatocellular carcinoma (HCC) in Chinese population evaluated by an updated systematic meta-analysis. PLoS One 8, e57043.
27. Xu J, Yin Z, Cao S, Gao W, Liu L, Yin Y, Liu P, and Shu Y (2013). Systematic review and meta-analysis on the association between IL-1B polymorphisms and cancer risk. PLoS One 8, e63654.
28. Wei Y, Liu F, Li B, Chen X, Ma Y, Yan L, Wen T, Xu M, Wang W, and Yang J (2011). Polymorphisms of tumor necrosis factor-alpha and hepatocellular carcinoma risk: a huge systematic review and meta-analysis. Dig Dis Sci 8, 2227-2236.
29. Uitterlinden AG, Fang Y, Van Meurs JB, Pols HA, and Van Leeuwen JP (2004). Genetics and biology of vitamin D receptor polymorphisms. Gene 338, 143-156.
30. Baur K, Mertens JC, Schmitt J, Iwata R, Stieger B, Frei P, Seifert B, Bischoff Ferrari HA, von Eckardstein A, and Müllhaupt B, et al (2012). The vitamin D receptor gene bAt (CCA) haplotype impairs the response to pegylated-interferon/ribavirin-based therapy in chronic hepatitis C patients. Antivir Ther 17, 541-547.
31. García-Martín E, Agúndez JA, Maestro ML, Suárez A, Vidaurreta M, Martínez C, Fernández-Pérez C, Ortega L, and Ladero JM (2013). Influence of vitaminD-related gene polymorphisms (CYP27B and VDR) on the response to interferon/ribavirin therapy in chronic hepatitis C. PLoS One 8, e74764.
32. Baur K, Mertens JC, Schmitt J, Iwata R, Stieger B, Eloranta JJ, Frei P, Stickel F, Dill MT, and Seifert B, et al (2012). Combined effect of 25-OH vitamin D plasma levels and genetic vitamin D receptor (NR 1I1) variants on fibrosis progression rate in HCV patients. Liver Int 32, 635-643.
33. Falleti E, Bitetto D, Fabris C, Cussigh A, Fontanini E, Fornasiere E, Fumolo E, Bignulin S, Cmet S, and Minisini R, et al (2010). Vitamin D receptor gene polymorphisms and hepatocellular carcinoma in alcoholic cirrhosis. World J Gastroenterol 16, 3016-3024.
34. Lange CM, Miki D, Ochi H, Nischalke HD, Bojunga J, Bibert S, Morikawa K, Gouttenoire J, Cerny A, and Dufour JF, et al (2013). Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development. PLoS One 8, e64053.
35. Wang TJ, Zhang F, Richards JB, Kestenbaum B, van Meurs JB, Berry D, Kiel DP, Streeten EA, Ohlsson C, and Koller DL, et al (2010). Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet 376, 180-188.
36. Rosen CJ (2011). Clinical practice. Vitamin D insufficiency. N Engl J Med 364, 248-254.