Vitamin D-receptor genotypes as independent genetic predictors of decreased bone mineral density in primary biliary cirrhosis

Gastroenterology

Volumn 118, Issue 1, 2000, Pages 145-151

  Springer, Jonathon E ^a   Cole, David E C ^a,b,c,d   Rubin, Laurence A ^a,c   CauchDudek, Karen ^a   Harewood, Laomi ^a   Evrovski, Jovan ^d   Peltekova, Vanya D ^d   Heathcote, E Jenny ^a  

^a Mathematics and Computer Science   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d Depts of Pathol and Lab Medicine   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

VITAMIN D RECEPTOR;

ADULT; AGED; ARTICLE; BODY WEIGHT; BONE ATROPHY; BONE DENSITY; BONE MASS; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; FEMALE; GENETIC SUSCEPTIBILITY; HUMAN; LUMBAR SPINE; MAJOR CLINICAL STUDY; OSTEOPOROSIS; POSTMENOPAUSE; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; RISK FACTOR;

EID: 0033985622     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(00)70423-9     Document Type: Article

References (44)

1. AJ Stellon A Davies J Compston R Williams Osteoporosis in chronic cholestatic liver disease Q J Med 57 1985 783 790
2. SF Hodgson ER Dickson HW Wahner KA Johnson KG Mann BL Riggs Bone loss and reduced osteoblast function in primary biliary cirrhosis Ann Intern Med 103 1985 855 860
3. N Guanabens A Pares L Marinoso A Brancos C Piera S Serrano F Rivera J Rodes Factors influencing the development of metabolic bone disease in primary biliary cirrhosis Am J Gastroenterol 85 1990 1356 1362
4. AJ Stellon A Webb J Compston R Williams Low bone turnover state in primary biliary cirrhosis Hepatology 7 1987 137 142
5. MS Shih C. Anderson Does “hepatic osteodystrophy” differ from peri- and postmenopausal osteoporosis? A histomorphic study Calcif Tissue Int 41 1987 187 191
6. SF Hodgson ER Dickson R Eastell EF Eriksen SC Bryant BL Riggs Rates of cancellous bone remodeling and turnover in osteopenia associated with primary biliary cirrhosis Bone 14 1993 819 827
7. RG Long E Meinhard RK Skinner Z Varghese MR Wills S Sherlock Clinical, biochemical and histological studies of osteomalacia, osteoporosis and parathyroid function in chronic liver disease Gut 19 1978 85 90
8. T Diamond D Stiel R Mason D Lissner D Bikle S Wilson S Posen Serum vitamin D metabolites are not responsible for low turnover osteoporosis in chronic liver disease J Clin Endocrinol Metab 69 1989 1234 1238
9. T Diamond D Stiel M Lunzer M Wilkinson J Roche S Posen Osteoporosis and skeletal fractures in chronic liver disease Gut 31 1990 82 87
10. R Olsson C Johansson G Lindstedt D Mellstrom Risk factors for bone loss in chronic active hepatitis and primary biliary cirrhosis Scand J Gastroenterol 29 1994 753 756
11. GW McCaughan RB Feller Osteoporosis in chronic liver disease: pathogenesis, risk factors, and management Dig Dis 12 1994 223 231
12. NA Pocock JA Eisman JL Hopper MG Yeates PN Sambrook S Eberl Genetic determinants of bone mass in adults: a twin study J Clin Invest 80 1987 706 710
13. NA Morrison JC Qi A Tokita P Kelly L Crofts TV Nguyen PN Sambrook J Eisman Prediction of bone density from vitamin D receptor alleles Nature 367 1994 284 287
14. GS Cooper DM Umbach Are vitamin D receptor polymorphisms associated with bone mineral density? A meta-analysis J Bone Miner Res 12 1996 1841 1849
15. C Gross TR Eccleshall D Feldman Vitamin D receptor alleles and osteoporosis JP Bilizekian LG Raisz GA Rodan Principles of bone biology 1996 Academic San Diego, CA 917 933
16. B Dawson-Hughes S Harris S Finnerman Calcium absorption on high and low calcium intake in relation to vitamin D receptor genotype J Clin Endocrinol Metab 80 1995 3657 3661
17. L Gennari L Becherini L Masi S Gonnelli C Cepollaro S Martini R Mansani ML Brandi Vitamin D receptor genotypes and intestinal calcium absorption in postmenopausal women Calcif Tissue Int 61 1997 460 463
18. H Howard T Nguyen N Morrison T Watanabe P Sambrook J Eisman PJ Kelly Genetic influences on bone density: physiological correlates of vitamin D receptor gene alleles in premenopausal women J Clin Endocrinol Metab 80 1995 2800 2805
19. World Health Organization Assessment of fracture risk and its application to screening for postmenopausal osteoporosis 1994 World Health Organization Geneva Technical report no. 843
20. AG Uitterlinden HAP Pols H Burger Q Huang PLA Van Daele CM Van Duijn A Hofman JC Birkenhager JPTM Van leeuwen A large population-based study of the association of vitamin D receptor gene polymorphisms with bone mineral density J Bone Miner Res 11 1996 1241 1248
21. V Peltekova DEC Cole G Hawker AG Pavlova LA Rubin Improved method for direct haplotyping at the vitamin D3 receptor locus Clin Biochem 31 1998 191 194
22. LA Rubin GA Hawker DEC Cole V Peltekova L Fielding R Ridout Determinants of peak bone mass: clinical and genetic analyses in a young female Canadian cohort J Bone Miner Res 4 1997 633 643
23. JM Shapiro H Smith F Schaffner Serum bilirubin: a prognostic factor in primary biliary cirrhosis Gut 20 1979 137 140
24. M Atkinson BEC Nordin S Sherlock Malabsorption and bone disease in prolonged obstructive jaundice Q J Med 99 1956 299 312
25. 3 treatment Gastroenterology 83 1982 97 102
26. EJ Hay Bone disease in cholestatic liver disease Gastroenterology 108 1995 276 283
27. HC Mitchison AJ Malcolm MF Bassendine OFW James Metabolic bone disease in primary biliary cirrhosis at presentation Gastroenterology 94 1988 463 470
28. JI Aguilar J Radick V Kodali S Levis R Altman JA Sadowski KR Reddy LJ Jeffers T Parker ER Schill Bone disease and plasma vitamin K levels in PBC patients (abstr) Gastroenterology 104 1993 A868
29. JA Cuthbert CYC Pak JE Zerwekh KD Glass B Combes Bone disease in primary biliary cirrhosis: increased bone resorption and turnover in the absence of osteoporosis or osteomalacia Hepatology 4 1984 1 8
30. R Vassilopoulou-Sellin N Rey-Bear CO Oyedeji Bilirubin as an inhibitor of cartilage metabolism: effect on avian chondrocyte proliferation in cell culture J Bone Miner Res 5 1990 769 774
31. CH Janes ER Dickson R Okazaki S Bonde AF McDonagh BL Riggs Role of hyperbilirubinemia in the impairment of osteoblast proliferation associated with cholestatic jaundice J Clin Invest 95 1995 2581 2586
32. R Eastell ER Dickson SF Hodgson RH Wiesner MK Porayko HW Wahner SL Cedel BL Riggs RAF Krom Rates of vertebral bone loss before and after liver transplantation in women with primary biliary cirrhosis Hepatology 14 1991 296 300
33. JS Crippin RA Jorgensen ER Dickson KD Lindor Hepatic osteodystrophy in primary biliary cirrhosis: effects of medical treatment Am J Gastroenterol 89 1994 47 50
34. KD Lindor CH Janes JS Crippin RA Jorgensen ER Dickson Bone disease in primary biliary cirrhosis: does ursodeoxycholic acid make a difference? Hepatology 21 1995 389 392
35. MR Kilmurry EJ Heathcote K Cauch-Dudek K O'Rourke RJ Bailey LM Blendis CN Ghent GY Minuk SC Pappas LJ Scully UP Steinbrecher LR Sutherland CN Williams LJ Worobetz Is the mayo model for predicting survival useful after the introduction of ursodeoxycholic acid treatment for primary biliary cirrhosis? Hepatology 23 1996 1148 1153
36. CW Slemenda JC Christian CJ Williams JA Norton CC Johnson Genetic determinants of bone mass in adult women: a reevaluation of the twin model and the potential importance of gene interaction on heritability estimates J Bone Miner Res 6 1991 561 567
37. SH Ralston The genetics of osteoporosis Q J Med 90 1997 247 251
38. BL Riggs TV Nguyen LJ Melton NA Morrison WM O'Fallon PJ Kelly KS Egan PN Sambrook JM Muhs JA Eisman The contribution of vitamin D receptor alleles to the determination of bone mineral density in normal and osteoporotic women J Bone Miner Res 10 1995 991 996
39. R Gueguen P Jouanny F Guillemin C Kuntz J Pourel G Seist Segregation analysis and variance components analysis of bone mineral density in healthy families J Bone Miner Res 10 1995 2017 2022
40. JA Eisman Vitamin D receptor gene alleles and osteoporosis: an affirmative view J Bone Miner Res 10 1995 1289 1293
41. M Peacock Vitamin D receptor gene alleles and osteoporosis: a contrasting view J Bone Miner Res 10 1995 1294 1297
42. D Marshall O Johnell H Wedel Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures BMJ 312 1996 1254 1259
43. A Torres M Machado MT Concepcion N Martin V Lorenzo D Henandez AP Rodriguez A Rodriguez E De Bonis JM Gonzalez-Posada A Hernandez E Salido Influence of vitamin D receptor genotype on bone mass changes after renal transplantation Kidney Int 50 1996 1726 1733
44. A Gough P Sambrook J Devlin L Lilley A Huisoon J Betteridge J Franklyn T Nguyen N Morrison J Eisman P Emery Effect of vitamin D receptor gene alleles on bone loss in early rheumatoid arthritis J Rheumatol 25 1998 864 868