Multiparameter high-throughput mechanical phenotyping

17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013

Volumn 1, Issue , 2013, Pages 383-385

  Masaeli, Mahdokht ^a,b   Tse, Henry T K ^a,b,c   Gossett, Daniel R ^a,b,c   Gupta, Dewal ^a,b   Di Carlo, Dino ^a,b  

^a Engineering IV   (United States)

^b CALIFORNIA NANOSYSTEMS INSTITUTE   (United States)

^c CytoVale Inc   (United States)

Author keywords

Label free assay; Mechanical phenotyping; Microfluidics; Multiparameter analysis

Indexed keywords

CYTOLOGY; DEFORMATION; MICROFLUIDICS; STEM CELLS; STRAIN;

CHROMATIN ORGANIZATION; INFORMATION CONTENTS; LABEL-FREE ASSAYS; MORPHOLOGICAL PARAMETERS; MULTIPARAMETER ANALYSIS; PHENOTYPING; PLURIPOTENT STEM CELLS; TIME-DEPENDENT STRAINS;

BIOMECHANICS;

EID: 84907301778     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (5)

1. Gossett, D. R. et al. Hydrodynamic stretching of single cells for large population mechanical phenotyping. Proceedings of the National Academy of Sciences of the United States of America 109, 7630-7635, doi:10.1073/pnas. 1200107109 (2012).
2. Pajerowski, J. D., Dahl, K. N., Zhong, F. L., Sammak, P. J. & Discher, D. E. Physical plasticity of the nucleus in stem cell differentiation. Proceedings of the National Academy of Sciences of the United States of America 104, 15619-15624, doi:0702576104 [pii] 10.1073/pnas.0702576104 (2007).
3. Dahl, K. N., Ribeiro, A. J. & Lammerding, J. Nuclear shape, mechanics, and mechanotransduction. Circulation research 102, 1307-1318, doi:10.1161/CIRCRESAHA.108.173989 (2008).
4. Zwerger, M., Ho, C. Y. & Lammerding, J. Nuclear Mechanics in Disease. Annu. Rev. Biomed. Eng. 13, 397-428 (2011).
5. Masaeli, M., Tse, H. T. K., Gossett, D. R., Clark, A. T. & Di Carlo, D. Deformability cytometry of embryonic stem cells reveals consistent mechanical properties across cell lines. The Sixteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences (2012).