Deficiency of GDNF receptor GFRα1 in Alzheimer's neurons results in neuronal death

Journal of Neuroscience

Volumn 34, Issue 39, 2014, Pages 13127-13138

  Konishi, Yoshihiro ^a,c,c   Yang, Li Bang ^a,g   He, Ping ^a   Lindholm, Kristina ^a   Lu, Bai ^b   Li, Rena ^a,d   Shen, Yong ^a,e,f  

^a ROSKAMP INSTITUTE   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c National Tottori Medical Center   (Japan)

^d BEIJING INSTITUTE FOR BRAIN DISORDERS   (China)

^e UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^g UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Neurodegeneration; Neuron

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 4 AMINOBUTYRIC ACID; 6 CYANO 7 NITRO 2, 3 QUINOXALINEDIONE; ACETYLCHOLINE; ANTISENSE OLIGONUCLEOTIDE; ARTEMIN; CALCIUM; GDNF FAMILY RECEPTOR SUBTYPE ALPHA 1; GDNF FAMILY RECEPTOR SUBTYPE ALPHA 2; GDNF FAMILY RECEPTOR SUBTYPE ALPHA 3; GDNF FAMILY RECEPTOR SUBTYPE ALPHA 4; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR RECEPTOR; GLUTAMATE RECEPTOR; MESSENGER RNA; NERVE CELL ADHESION MOLECULE; NEUROFILAMENT PROTEIN; NEURTURIN; PERSEPHIN; UNCLASSIFIED DRUG; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMPA RECEPTOR; GFRA1 PROTEIN, HUMAN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN RET;

AGED; ALZHEIMER DISEASE; ARTICLE; AUTOPSY; BIOCHEMISTRY; BRAIN CELL; BRAIN TISSUE; CELL SURVIVAL; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; MALE; NERVE CELL NECROSIS; NERVE FIBER GROWTH; NEUROPATHOLOGY; NEUROTRANSMISSION; PHASE CONTRAST MICROSCOPY; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; VERY ELDERLY; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; APOPTOSIS; CASE CONTROL STUDY; CELL CULTURE; DEFICIENCY; DRUG EFFECTS; GENETICS; METABOLISM; NERVE CELL; PATHOLOGY;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOPTOSIS; CASE-CONTROL STUDIES; CELLS, CULTURED; FEMALE; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS; HUMANS; MALE; NEURAL CELL ADHESION MOLECULES; NEURONS; PROTO-ONCOGENE PROTEINS C-RET; RECEPTORS, AMPA; RECEPTORS, GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 84907284563     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2582-13.2014     Document Type: Article

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