Neurons with choline acetyltransferase immunoreactivity and mRNA are present in the human cerebral cortex

Histochemistry and Cell Biology

Volumn 111, Issue 3, 1999, Pages 197-207

  Kasashima, Satomi ^a   Kawashima, Atsuhiro ^a   Muroishi, Youko ^a   Futakuchi, Hiroko ^a   Nakanishi, Isao ^a   Oda, Yoshio ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE ACETYLTRANSFERASE;

ACETYLCHOLINE BRAIN LEVEL; ADULT; AGED; ARTICLE; BRAIN CORTEX; BRAIN REGION; CELLULAR DISTRIBUTION; CHOLINERGIC NERVE; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; MALE; NEUROTRANSMISSION; PRIORITY JOURNAL;

AUTOPSY; BLOTTING, WESTERN; CEREBRAL CORTEX; CHOLINE O-ACETYLTRANSFERASE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; NEURONS; RNA, MESSENGER;

EID: 0033016937     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004180050349     Document Type: Article

References (48)

1. Armstrong DM, Saper CB, Levey AI, Wainer BH, Terry RD (1983) Distribution of cholinergic neurons in rat brain: demonstrated by the immunocytochemical localization of choline acetyltransferase. J Comp Neurol 216:53-68
2. Arvidsson U, Riedl M, Elde R, Meister B (1997) Vesicular acetylcholine transporter (VAChT) protein: a novel and unique marker for cholinergic neurons in the central and peripheral nervous systems. J Comp Neurol 378:454-467
3. Avendaño C, Umbriaco D, Dykes RW, Descarries L (1996) Acetylcholine innervation of sensory and motor neocortical areas in adult cat: a choline acetyltransferase immunohistochemical study. J Chem Neuroanat 11:113-130
4. Barber RP, Phelps PE, Houser CR, Crawford GD, Salvaterra PM, Vaughn JE (1984) The morphology and distribution of neurons containing choline acetyltransferase in the adult rat spinal cord: an immunocytochemical study. J Comp Neurol 229:329-346
5. Bruce G, Wainer BH, Hersh LB (1985) Immunoaffinity purification of human choline acetyltransferase: comparison of the brain and placental enzymes. J Neurochem 45:611-620
6. Butcher LL, Woolf NJ (1986) Central cholinergic systems: synopsis of anatomy and overview of physiology and pathology. In: Scheibel AB, Wechsler AF (eds) The biological substrates of Alzheimer's disease. Academic Press, New York, pp 73-86
7. Butcher LL, Oh JD, Woolf NJ, Edwards RH, Roghani A (1992) Organization of central cholinergic neurons revealed by combined in situ hybridization histochemistry and choline-O-acetyltransferase immunocytochemistry. Neurochem Int 21:429-445
8. Cavicchioli L, Flanigan TP, Dickson JG, Vantini G, Dal Toso R, Fusco M, Walsh FS, Leon A (1991) Choline acetyltransferase messenger RNA expression in developing and adult rat brain: regulation by nerve growth factor. Mol Brain Res 9:319-325
9. Cossette P, Umbriaco D, Zamar N, Hamel E, Descarries L (1993) Recovery of choline acetyltransferase activity without sprouting of the residual acetylcholine innervation in adult rat cerebral cortex after lesion of the nucleus basalis. Brain Res 630:195-206
10. Eckenstein FP, Baughman RW, Quinn J (1988) An anatomical study of cholinergic innervation in rat cerebral cortex. Neuroscience 25:457-474
11. Economo C von (1929) The cytoarchitectonics of the human cerebral cortex. Oxford University Press, London
12. Gilmor ML, Nash NR, Roghani A, Edwards RH, Yi H, Hersh SM, Levey AI (1996) Expression of the putative vesicular acetylcholine transporter in rat brain and localization in cholinergic synaptic vesicles. J Neurosci 16:2179-2190
13. Hedreen JC, Bacon SJ, Cork LC, Kitt CA, Crawford GD, Salvaterra PM, Price DL (1983) Immunocytochemical identification of cholinergic neurons in the monkey nervous system using monoclonal antibodies against choline acetyltransferase. Neurosci Lett 43:173-177
14. Hendry SHC, Jones EG, Killackey HP, Chalupa LM (1987) Choline acetyltransferase-immunoreactive neurons in fetal monkey cerebral cortex. Dev Brain Res 37:313-317
15. Houser CR, Crawford GD, Barber RP, Salvaterra PM, Vaughn JE (1983) Organization and morphological characteristics of cholinergic neurons: an immunocytochemical study with a monoclonal antibody to choline acetyltransferase. Brain Res 266: 97-119
16. Houser CR, Crawford GD, Salvaterra PM, Vaughn JE (1985) Immunocytochemical localization of choline acetyltransferase in rat cerebral cortex: a study of cholinergic neurons and synapses. J Comp Neurol 234:17-34
17. Ibáñez CF, Ernfors P, Persson H (1991) Developmental and regional expression of choline acetyltransferase mRNA in the rat central nervous system. J Neurosci Res 29:163-171
18. Ichikawa T, Hirata Y (1986) Organization of choline acetyltransferase-containing structures in the forebrain of the rat. J Neurosci 6:281-292
19. Ichikawa T, Ishida I, Hirata Y, Deguchi T (1987) Monoclonal antibodies to monkey brain choline acetyltransferase: production and immunohistochemistry. Neurosci Lett 81:24-28
20. Ichikawa T, Ohsako S, Deguchi T (1991) Production of an antiserum using a fusion protein produced by a cDNA for rat choline acetyltransferase. Neurosci Lett 131:213-216
21. Ichikawa T, Ajiki K, Matsuura J, Misawa H (1997) Localization of two cholinergic markers, choline acetyltransferase and vesicular acetylcholine transporter in the central nervous system of the rat: in situ hybridization immunohistochemistry and immunohistochemistry. J Chem Neuroanat 13:23-39
22. Ishii K, Oda Y, Ichikawa T, Deguchi T (1990) Complementary DNAs for choline acetyltransferase from spinal cords of rat and mouse: nucleotide sequences, expression in mammalian cells and in situ hybridization. Brain Res Mol Brain Res 7:151-159
23. Kasashima S, Muroishi Y, Futakuchi H, Nakanishi I, Oda Y (1998) In situ mRNA hybridization study of the distribution of choline acetyltransferase in the human brain. Brain Res 806: 8-15
24. Kimura H, McGeer PL, Peng F, McGeer EG (1980) Choline acetyltransferase-containing neurons in rodent brain demonstrated by immunohistochemistry. Science 208:1057-1059
25. Kimura H, McGeer PL, Peng HJ, McGeer EG (1981) The central cholinergic system studied by choline acetyltransferase immunohistochemistry in the cat. J Comp Neurol 200:151-201
26. Kosaka T, Tauchi M, Dahl JL (1988) Cholinergic neurons containing GABA-like and/or glutamic acid decarboxylase-like immunoreactivities in various brain regions of the rat. Exp Brain Res 70:605-617
27. Lauterborn JC, Isackson PJ, Montalvo R, Gall CM (1993) In situ hybridization localization of choline acetyltransferase mRNA in adult rat brain and spinal cord. Mol Brain Res 17:59-69
28. Lehéricy S, Hirsch EC, Cervera-Piérot P, Hersh LB, Bakchine S, Piette F, Duyckaerts C, Hauw J-J, Javoy-Agid F, Agid Y (1993) Heterogeneity and selectivity of the degeneration of cholinergic neurons in the basal forebrain of patients with Alzheimer's disease. J Comp Neurol 330:15-31
29. Levey AI, Wainer BH, Rye DB, Mufson EJ, Mesulam M-M (1984) Choline acetyltransferase-immunoreactive neurons intrinsic to rodent cortex and distinction from acetylcholinesterase-positive neurons. Neuroscience 13:341-353
30. Mesulam M-M, Mufson EJ, Wainer BH, Levey AI (1983) Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6). Neuroscience 10:1185-1201
31. Mesulam M-M, Geula C, Cosgrove R, Mash D, Brimijoin S (1991) Immunocytochemical demonstration of axonal and perikaryal acetylcholinesterase in human cerebral cortex. Brain Res 539:233-238
32. Mesulam M-M, Mash D, Hersh LB, Bothwell M, Geula C (1992) Cholinergic innervation of the human striatum, globus pallidus, subthalamic nucleus, substantia nigra, and red nucleus. J Comp Neurol 323:252-268
33. Mizukawa K, McGeer PL, Tago H, Peng JH, McGeer EG, Kimura H (1986) The cholinergic system of the human hindbrain studied by choline acetyltransferase immunohistochemistry and acetylcholinesterase histochemistry. Brain Res 379:39-55
34. Oda Y, Nakanishi I, Deguchi T (1992) A complementary DNA for human choline acetyltransferase induces two forms of enzyme with different molecular weights in cultured cells. Mol Brain Res 16:287-294
35. Oda Y, Imai S, Nakanishi I, Ichikawa T, Deguchi T (1995) Immunohistochemical study on choline acetyltransferase in the spinal cord of patients with amyotrophic lateral sclerosis. Pathol Int 45:933-939
36. Oda Y, Yamashita N, Muroishi Y, Nakanishi I (1996) Localization of choline acetyltransferase and acetylcholine in the chorion of early human pregnancy. Histochem Cell Biol 105:93-99
37. Oh JD, Woolf NJ, Roghani A, Edwards RH, Butcher LL. (1992) Cholinergic neurons in the rat central nervous system demonstrated by in situ hybridization of choline acetyltransferase mRNA. Neuroscience 47:807-822
38. Parent A (1996) Cerebral cortex: In: Carpenter's human neuroanatomy, 9th edn. Williams and Wilkins, Baltimore, pp 864-936
39. Satoh K, Fibiger HC (1985) Distribution of central cholinergic neurons in the baboon (Papio papio). I. General morphology. J Comp Neurol 236:197-214
40. Schäfer MK-H, Weihe E, Varoqui H, Eiden LE, Erickson JD (1994) Distribution of the vesicular acetylcholine transporter (VAChT) in the central and peripheral nervous systems of the rat. J Mol Neurosci 5:1-26
41. Selden N, Geula C, Hersh L, Mesulam M-M (1994) Human striatum: chemoarchitecture of the caudate nucleus, putamen and ventral striatum in health and Alzheimer's disease. Neuroscience 60:621-636
42. Sofroniew MV, Eckenstein F, Thoenen H, Cuello AC (1982) Topography of choline acetyltransferase-containing neurons in the forebrain of the rat. Neurosci Lett 33:7-12
43. Stichel CC, Dolabela de Lima A, Singer W (1987) A search for choline acetyltransferase-like immunoreactivity in neurons of cat striate cortex. Brain Res 405:395-399
44. Tago H, McGeer PL, McGeer EG, Akiyama H, Hersh LB (1989) Distribution of choline acetyltransferase immunopositive structures in the rat brainstem. Brain Res 495:271-297
45. Umbriaco D, Watkins KC, Descarries L, Cozzari C, Hartman BK (1994) Ultrastructural and morphometric features of the acetylcholine innervation in adult rat parietal cortex: an electron microscopic study in serial sections. J Comp Neurol 348:351-373
46. Wainer BH, Levey AI, Mufson EJ, Mesulam M-M. (1984) Cholinergic systems in mammalian brain identified with antibodies against choline acetyltransferase. Neurochem Int 6:163-182
47. Weihe E, Tao-Cheng J-H, Schäfer MK-H, Erickson JD, Eiden LE (1996) Visualization of the vesicular acetylcholine transporter in cholinergic nerve terminals and its targeting to a specific population of small synaptic vesicles. Proc Natl Acad Sci USA 93:3547-3552
48. Woolf NJ (1991) Cholinergic systems in mammalian brain and spinal cord. Prog Neurobiol 37:475-524