Elevated neutrophil-to-lymphocyte ratio in squamous cell carcinoma of larynx compared to benign and precancerous laryngeal lesions

Asian Pacific Journal of Cancer Prevention

Volumn 15, Issue 17, 2014, Pages 7351-7355

  Kum, Rauf Oguzhan ^a   Ozcan, Muge ^a   Baklaci, Deniz ^a   Kum, Nurcan Yurtsever ^a   Yilmaz, Yavuz Fuat ^a   Gungor, Volkan ^a   Unal, Adnan ^b  

^a ANKARA TRAINING AND RESEARCH HOSPITAL   (Turkey)

^b HITIT UNIVERSITY   (Turkey)

Author keywords

Neutrophil lymphocyte ratio; Preneoplasia; Squamous cell carcinoma of larynx

Indexed keywords

ADULT; AGED; BLOOD; CARCINOMA IN SITU; CARCINOMA, SQUAMOUS CELL; CYTOLOGY; FEMALE; HEAD AND NECK NEOPLASMS; HUMAN; LARYNGEAL DISEASES; LARYNGEAL NEOPLASMS; LARYNGITIS; LYMPHOCYTE; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; NEUTROPHIL; POLYPS; PRECANCEROUS CONDITIONS; PROGNOSIS; RETROSPECTIVE STUDY; TUMOR RECURRENCE;

ADULT; AGED; CARCINOMA IN SITU; CARCINOMA, SQUAMOUS CELL; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; LARYNGEAL DISEASES; LARYNGEAL NEOPLASMS; LARYNGITIS; LYMPHOCYTE COUNT; LYMPHOCYTES; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEUTROPHILS; POLYPS; PRECANCEROUS CONDITIONS; PROGNOSIS; RETROSPECTIVE STUDIES;

EID: 84907272459     PISSN: 15137368     EISSN: None     Source Type: Journal    
DOI: 10.7314/APJCP.2014.15.17.7351     Document Type: Article

References (30)

1. An X, Ding PR, Wang FH, Jiang WQ, Li YH (2011). Elevated neutrophil to lymphocyte ratio predicts poor prognosis in nasopharyngeal carcinoma. Tumour Biol, 32, 317-24.
2. Azab B, Bhatt VR, Phookan J, et al (2012). Usefulness of the neutrophil-to-lymphocyte ratio in predicting short-and long-term mortality in breast cancer patients. Ann Surg Oncol, 19, 217-24.
3. Coussens LM, Werb Z (2002). Inflammation and cancer. Nature, 420, 860-7.
4. Ferlito A, Devaney KO, Woolgar JA, et al (2012). Squamous epithelial changes of the larynx: diagnosis and therapy. Head Neck, 34, 1810-6.
5. Gale N, Pilch BZ, Sidransky D, Westra W, Califano J (2005). Tumours of the hypopharynx, larynx and trachea (epithelial precursor lesions).In 'World Health Organization Classification of Tumours: Pathology and Genetics of Head and Neck Tumours', L. Barnes, J. W. Eveson, P. Reichart and D. Sidranksy. IARC Press, Lyon, France., 140-3.
6. Haddad RI, Shin DM (2008). Recent advances in head and neck cancer. N Engl J Med, 359, 1143-54.
7. Hanahan D, Weinberg RA (2011). Hallmarks of cancer: the next generation. Cell, 144, 646-74.
8. Idowu OK, Ding Q, Taktak AF, Chandrasekar CR, Yin Q (2012). Clinical implication of pretreatment neutrophil to lymphocyte ratio in soft tissue sarcoma. Biomarkers, 17, 539-44.
9. Jaiswal M, LaRusso NF, Burgart LJ, Gores GJ (2000). Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism. Cancer Res, 60, 184-90.
10. Jemal A, Siegel R, Ward E, et al (2008). Cancer statistics, 2008. CA Cancer J Clin, 58, 71-96.
11. Jung MR, Park YK, Jeong O, et al (2011). Elevated preoperative neutrophil to lymphocyte ratio predicts poor survival following resection in late stage gastric cancer. J Surg Oncol, 104, 504-10.
12. Kacan T, Babacan NA, Seker M, et al (2014). Could the neutrophil to lymphocyte ratio be a poor prognostic factor for non small cell lung cancers? Asian Pac J Cancer Prev, 15, 2089-94.
13. Karaman H, Karaman A, Erden A, et al (2013). Relationship between colonic polyp type and the neutrophil/ lymphocyte ratio as a biomarker. Asian Pac J Cancer Prev, 14, 3159-61.
14. Kemal Y, Yucel I, Ekiz K, et al (2014). Elevated serum neutrophil to lymphocyte and platelet to lymphocyte ratios could be useful in lung cancer diagnosis. Asian Pac J Cancer Prev, 15, 2651-4.
15. Liu CL, Lee JJ, Liu TP, et al (2013). Blood neutrophil-to-lymphocyte ratio correlates with tumor size in patients with differentiated thyroid cancer. J Surg Oncol, 107, 493-7.
16. Marcos CA, Alonso-Guervos M, Prado NR, et al (2011). Genetic model of transformation and neoplastic progression in laryngeal epithelium. Head Neck, 33, 216-24.
17. Menges T, Engel J, Welters I, et al (1999). Changes in blood lymphocyte populations after multiple trauma: association with posttraumatic complications. Crit Care Med, 27, 733-40.
18. Millrud CR, Kvarnhammar AM, Uddman R, et al (2012). The activation pattern of blood leukocytes in head and neck squamous cell carcinoma is correlated to survival. PLoS One, 7, e51120.
19. Nankivell P, Weller M, McConkey C, Paleri V, Mehanna H (2011). Biomarkers in laryngeal dysplasia: a systematic review. Head Neck, 33, 1170-6.
20. Ozdemir Y, Akin ML, Sucullu I, Balta AZ, Yucel E (2014). Pretreatment neutrophil/lymphocyte ratio as a prognostic aid in colorectal cancer. Asian Pac J Cancer Prev, 15, 2647-50.
21. Perisanidis C, Kornek G, Poschl PW, et al (2013). High neutrophil-to-lymphocyte ratio is an independent marker of poor disease-specific survival in patients with oral cancer. Med Oncol, 30, 1-8.
22. Rassouli A, Saliba J, Castano R, Hier M, Zeitouni AG (2013). Systemic inflammatory markers as independent prognosticators of head and neck squamous cell carcinoma. Head Neck, [Epub ahead of print].
23. Roxburgh CS, McMillan DC (2010). Role of systemic inflammatory response in predicting survival in patients with primary operable cancer. Future Oncology, 6, 149-63.
24. Sadri M, McMahon J, Parker A (2006). Laryngeal dysplasia: aetiology and molecular biology. J Laryngol Otol, 120, 170-7.
25. Seretis C, Gourgiotis S, Gemenetzis G, et al (2013). The significance of neutrophil/lymphocyte ratio as a possible marker of underlying papillary microcarcinomas in thyroidal goiters: a pilot study. Am J Surg, 205, 691-6.
26. Teramukai S, Kitano T, Kishida Y, et al (2009). Pretreatment neutrophil count as an independent prognostic factor in advanced non-small-cell lung cancer: an analysis of Japan Multinational Trial Organisation LC00-03. Eur J Cancer, 45, 1950-8.
27. Trellakis S, Bruderek K, Dumitru CA, et al (2011). Polymorphonuclear granulocytes in human head and neck cancer: enhanced inflammatory activity, modulation by cancer cells and expansion in advanced disease. Int J Cancer, 129, 2183-93.
28. Tsai YD, Wang CP, Chen CY, et al (2013). Pretreatment circulating monocyte count associated with poor prognosis in patients with oral cavity cancer. Head Neck, 36, 947-53.
29. Unal D, Eroglu C, Kurtul N, Oguz A, Tasdemir A (2013). Are neutrophil/lymphocyte and platelet/lymphocyte rates in patients with non-small cell lung cancer associated with treatment response and prognosis? Asian Pac J Cancer Prev, 14, 5237-42.
30. Wenger FA, Jacobi CA, Zieren J, et al (1999). Tumor size and lymph-node status in pancreatic carcinoma-is there a correlation to the preoperative immune function? Langenbecks Arch Surg, 384, 473-8.