메뉴 건너뛰기




Volumn 30, Issue 1, 2013, Pages

High neutrophil-to-lymphocyte ratio is an independent marker of poor disease-specific survival in patients with oral cancer

Author keywords

Disease specific survival; Neutrophil to lymphocyte ratio; Oral cancer; Prognostic marker

Indexed keywords

ADULT; ADVANCED CANCER; ARTICLE; CANCER ADJUVANT THERAPY; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CELLULAR PARAMETERS; CHEMORADIOTHERAPY; COHORT ANALYSIS; DISEASE SPECIFIC SURVIVAL; FEMALE; HUMAN; LYMPHOCYTE; MAJOR CLINICAL STUDY; MALE; MOUTH SQUAMOUS CELL CARCINOMA; NEUTROPHIL; NEUTROPHIL TO LYMPHOCYTE RATIO; PERINEURAL INVASION; PREDICTIVE VALUE; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; RADIATION DOSE; RETROSPECTIVE STUDY;

EID: 84871720406     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-012-0334-5     Document Type: Article
Times cited : (92)

References (42)
  • 1
    • 76049128595 scopus 로고    scopus 로고
    • Estimates of cancer incidence and mortality in Europe in 2008
    • 20116997 10.1016/j.ejca.2009.12.014 1:STN:280:DC%2BC3c7js1CktA%3D%3D
    • Ferlay J, Parkin DM, Steliarova-Foucher E. Estimates of cancer incidence and mortality in Europe in 2008. Eur J Cancer. 2010;46:765-81.
    • (2010) Eur J Cancer , vol.46 , pp. 765-781
    • Ferlay, J.1    Parkin, D.M.2    Steliarova-Foucher, E.3
  • 2
    • 67349186933 scopus 로고    scopus 로고
    • Global epidemiology of oral and oropharyngeal cancer
    • 18804401 10.1016/j.oraloncology.2008.06.002
    • Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol. 2009;45:309-16.
    • (2009) Oral Oncol , vol.45 , pp. 309-316
    • Warnakulasuriya, S.1
  • 3
    • 84867997123 scopus 로고    scopus 로고
    • New approaches to EGFR inhibition for locally advanced or metastatic squamous cell carcinoma of the head and neck (SCCHN)
    • Agulnik M. New approaches to EGFR inhibition for locally advanced or metastatic squamous cell carcinoma of the head and neck (SCCHN). Med Oncol. 2012;29:2481-91.
    • (2012) Med Oncol. , vol.29 , pp. 2481-2491
    • Agulnik, M.1
  • 4
    • 32644475906 scopus 로고    scopus 로고
    • Histopathological prognosticators in oral and oropharyngeal squamous cell carcinoma
    • 16150633 10.1016/j.oraloncology.2005.05.008
    • Woolgar JA. Histopathological prognosticators in oral and oropharyngeal squamous cell carcinoma. Oral Oncol. 2006;42:229-39.
    • (2006) Oral Oncol , vol.42 , pp. 229-239
    • Woolgar, J.A.1
  • 5
    • 25844523780 scopus 로고    scopus 로고
    • Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501)
    • 16161069 10.1002/hed.20279
    • Bernier J, Cooper JS, Pajak TF, van Glabbeke M, Bourhis J, Forastiere A, et al. Defining risk levels in locally advanced head and neck cancers: a comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501). Head Neck. 2005;27:843-50.
    • (2005) Head Neck , vol.27 , pp. 843-850
    • Bernier, J.1    Cooper, J.S.2    Pajak, T.F.3    Van Glabbeke, M.4    Bourhis, J.5    Forastiere, A.6
  • 6
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • 11229684 10.1016/S0140-6736(00)04046-0 1:CAS:528:DC%2BD3MXhsVKltb0%3D
    • Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet. 2001;357:539-45.
    • (2001) Lancet , vol.357 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 7
    • 4043088499 scopus 로고    scopus 로고
    • IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • 15294155 10.1016/j.cell.2004.07.013 1:CAS:528:DC%2BD2cXmslKrs7o%3D
    • Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, Egan LJ, et al. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell. 2004;118:285-96.
    • (2004) Cell , vol.118 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3    Park, J.M.4    Li, Z.W.5    Egan, L.J.6
  • 8
    • 33845865825 scopus 로고    scopus 로고
    • Crosstalk between cancer and immune cells: Role of STAT3 in the tumour microenvironment
    • 17186030 10.1038/nri1995 1:CAS:528:DC%2BD28XhtlCht7fE
    • Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev Immunol. 2007;7:41-51.
    • (2007) Nat Rev Immunol , vol.7 , pp. 41-51
    • Yu, H.1    Kortylewski, M.2    Pardoll, D.3
  • 9
    • 77954156529 scopus 로고    scopus 로고
    • Stat3: Linking inflammation to epithelial cancer - More than a "gut" feeling?
    • 20478049 10.1186/1747-1028-5-14
    • Jarnicki A, Putoczki T, Ernst M. Stat3: linking inflammation to epithelial cancer - more than a "gut" feeling? Cell Div. 2010;5:14.
    • (2010) Cell Div , vol.5 , pp. 14
    • Jarnicki, A.1    Putoczki, T.2    Ernst, M.3
  • 10
    • 67650151005 scopus 로고    scopus 로고
    • Cancer-related inflammation, the seventh hallmark of cancer: Links to genetic instability
    • 19468060 10.1093/carcin/bgp127 1:CAS:528:DC%2BD1MXot1CisL8%3D
    • Colotta F, Allavena P, Sica A, Garlanda C, Mantovani A. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis. 2009;30:1073-81.
    • (2009) Carcinogenesis , vol.30 , pp. 1073-1081
    • Colotta, F.1    Allavena, P.2    Sica, A.3    Garlanda, C.4    Mantovani, A.5
  • 11
    • 77956898009 scopus 로고    scopus 로고
    • TNF-alpha and its inhibitors in cancer
    • 19277912 10.1007/s12032-009-9190-3 1:CAS:528:DC%2BC3cXlsVSqsb4%3D
    • Zidi I, Mestiri S, Bartegi A, Amor NB. TNF-alpha and its inhibitors in cancer. Med Oncol. 2010;27:185-98.
    • (2010) Med Oncol , vol.27 , pp. 185-198
    • Zidi, I.1    Mestiri, S.2    Bartegi, A.3    Amor, N.B.4
  • 12
    • 78650389810 scopus 로고    scopus 로고
    • High blood neutrophil-to-lymphocyte ratio is an indicator of poor prognosis in malignant mesothelioma patients undergoing systemic therapy
    • 20956618 10.1158/1078-0432.CCR-10-2245 1:CAS:528:DC%2BC3cXhsFamtLvN
    • Kao SC, Pavlakis N, Harvie R, Vardy JL, Boyer MJ, van Zandwijk N, et al. High blood neutrophil-to-lymphocyte ratio is an indicator of poor prognosis in malignant mesothelioma patients undergoing systemic therapy. Clin Cancer Res. 2010;16:5805-13.
    • (2010) Clin Cancer Res , vol.16 , pp. 5805-5813
    • Kao, S.C.1    Pavlakis, N.2    Harvie, R.3    Vardy, J.L.4    Boyer, M.J.5    Van Zandwijk, N.6
  • 13
    • 83055176733 scopus 로고    scopus 로고
    • Elevated preoperative neutrophil: Lymphocyte ratio as a predictor of postoperative disease recurrence in esophageal cancer
    • 21547702 10.1245/s10434-011-1754-8
    • Sharaiha RZ, Halazun KJ, Mirza F, Port JL, Lee PC, Neugut AI, et al. Elevated preoperative neutrophil: lymphocyte ratio as a predictor of postoperative disease recurrence in esophageal cancer. Ann Surg Oncol. 2011;18:3362-9.
    • (2011) Ann Surg Oncol , vol.18 , pp. 3362-3369
    • Sharaiha, R.Z.1    Halazun, K.J.2    Mirza, F.3    Port, J.L.4    Lee, P.C.5    Neugut, A.I.6
  • 14
    • 79954430604 scopus 로고    scopus 로고
    • Neutrophil/lymphocyte ratio predicts chemotherapy outcomes in patients with advanced colorectal cancer
    • 21448173 10.1038/bjc.2011.100 1:CAS:528:DC%2BC3MXks1ajur8%3D
    • Chua W, Charles KA, Baracos VE, Clarke SJ. Neutrophil/lymphocyte ratio predicts chemotherapy outcomes in patients with advanced colorectal cancer. Br J Cancer. 2011;104:1288-95.
    • (2011) Br J Cancer , vol.104 , pp. 1288-1295
    • Chua, W.1    Charles, K.A.2    Baracos, V.E.3    Clarke, S.J.4
  • 15
    • 67649304466 scopus 로고    scopus 로고
    • Pretreatment neutrophil count as an independent prognostic factor in advanced non-small-cell lung cancer: An analysis of Japan multinational trial organisation LC00-03
    • 19231158 10.1016/j.ejca.2009.01.023
    • Teramukai S, Kitano T, Kishida Y, Kawahara M, Kubota K, Komuta K, et al. Pretreatment neutrophil count as an independent prognostic factor in advanced non-small-cell lung cancer: an analysis of Japan multinational trial organisation LC00-03. Eur J Cancer. 2009;45:1950-8.
    • (2009) Eur J Cancer , vol.45 , pp. 1950-1958
    • Teramukai, S.1    Kitano, T.2    Kishida, Y.3    Kawahara, M.4    Kubota, K.5    Komuta, K.6
  • 16
    • 68249125161 scopus 로고    scopus 로고
    • Negative impact of neutrophil-lymphocyte ratio on outcome after liver transplantation for hepatocellular carcinoma
    • 19561458 10.1097/SLA.0b013e3181a77e59
    • Halazun KJ, Hardy MA, Rana AA, Woodland DCt, Luyten EJ, Mahadev S, et al. Negative impact of neutrophil-lymphocyte ratio on outcome after liver transplantation for hepatocellular carcinoma. Ann Surg. 2009;250:141-51.
    • (2009) Ann Surg , vol.250 , pp. 141-151
    • Halazun, K.J.1    Hardy, M.A.2    Rana, A.A.3    Woodland, D.4    Luyten, E.J.5    Mahadev, S.6
  • 17
    • 77955894120 scopus 로고    scopus 로고
    • Preoperative hematologic markers as independent predictors of prognosis in resected pancreatic ductal adenocarcinoma: Neutrophil-lymphocyte versus platelet-lymphocyte ratio
    • 20122680 10.1016/j.amjsurg.2009.08.041
    • Bhatti I, Peacock O, Lloyd G, Larvin M, Hall RI. Preoperative hematologic markers as independent predictors of prognosis in resected pancreatic ductal adenocarcinoma: neutrophil-lymphocyte versus platelet-lymphocyte ratio. Am J Surg. 2010;200:197-203.
    • (2010) Am J Surg , vol.200 , pp. 197-203
    • Bhatti, I.1    Peacock, O.2    Lloyd, G.3    Larvin, M.4    Hall, R.I.5
  • 18
    • 78149406896 scopus 로고    scopus 로고
    • Elevated preoperative neutrophil to lymphocyte ratio predicts risk of recurrence following curative resection for stage IIA colon cancer
    • 20821217 10.1007/s00384-010-1052-0
    • Ding PR, An X, Zhang RX, Fang YJ, Li LR, Chen G, et al. Elevated preoperative neutrophil to lymphocyte ratio predicts risk of recurrence following curative resection for stage IIA colon cancer. Int J Colorectal Dis. 2010;25:1427-33.
    • (2010) Int J Colorectal Dis , vol.25 , pp. 1427-1433
    • Ding, P.R.1    An, X.2    Zhang, R.X.3    Fang, Y.J.4    Li, L.R.5    Chen, G.6
  • 19
    • 67650481213 scopus 로고    scopus 로고
    • Lymphopenia as a prognostic factor for overall survival in advanced carcinomas, sarcomas, and lymphomas
    • 19549917 10.1158/0008-5472.CAN-08-3845 1:CAS:528:DC%2BD1MXnvFWqu7c%3D
    • Ray-Coquard I, Cropet C, Van Glabbeke M, Sebban C, Le Cesne A, Judson I, et al. Lymphopenia as a prognostic factor for overall survival in advanced carcinomas, sarcomas, and lymphomas. Cancer Res. 2009;69:5383-91.
    • (2009) Cancer Res , vol.69 , pp. 5383-5391
    • Ray-Coquard, I.1    Cropet, C.2    Van Glabbeke, M.3    Sebban, C.4    Le Cesne, A.5    Judson, I.6
  • 20
    • 84880314861 scopus 로고    scopus 로고
    • Comparison of the prognostic values of various inflammation based factors in patients with pancreatic cancer
    • Wang DS, Luo HY, Qiu MZ, Wang ZQ, Zhang DS, Wang FH et al. Comparison of the prognostic values of various inflammation based factors in patients with pancreatic cancer. Med Oncol. 2012;29:3092-100.
    • (2012) Med Oncol. , vol.29 , pp. 3092-4100
    • Wang, D.S.1    Luo, H.Y.2    Qiu, M.Z.3    Wang, Z.Q.4    Zhang, D.S.5    Wang, F.H.6
  • 21
    • 79951772403 scopus 로고    scopus 로고
    • The effect of peripheral blood values on prognosis of patients with locally advanced gastric cancer before treatment
    • 19847679 10.1007/s12032-009-9335-4
    • Aliustaoglu M, Bilici A, Ustaalioglu BB, Konya V, Gucun M, Seker M, et al. The effect of peripheral blood values on prognosis of patients with locally advanced gastric cancer before treatment. Med Oncol. 2010;27:1060-5.
    • (2010) Med Oncol , vol.27 , pp. 1060-1065
    • Aliustaoglu, M.1    Bilici, A.2    Ustaalioglu, B.B.3    Konya, V.4    Gucun, M.5    Seker, M.6
  • 22
    • 84869499334 scopus 로고    scopus 로고
    • Pretreatment levels of peripheral neutrophils and lymphocytes as independent prognostic factors in patients with nasopharyngeal carcinoma
    • He JR, Shen GP, Ren ZF, Qin H, Cui C, Zhang Y et al. Pretreatment levels of peripheral neutrophils and lymphocytes as independent prognostic factors in patients with nasopharyngeal carcinoma. Head Neck. 2012;34:1769-76.
    • (2012) Head Neck , vol.34 , pp. 1769-1776
    • He, J.R.1    Shen, G.P.2    Ren, Z.F.3    Qin, H.4    Cui, C.5    Zhang, Y.6
  • 23
    • 79953834525 scopus 로고    scopus 로고
    • Elevated neutrophil to lymphocyte ratio predicts poor prognosis in nasopharyngeal carcinoma
    • 21052888 10.1007/s13277-010-0124-7 1:CAS:528:DC%2BC3MXitleitrk%3D
    • An X, Ding PR, Wang FH, Jiang WQ, Li YH. Elevated neutrophil to lymphocyte ratio predicts poor prognosis in nasopharyngeal carcinoma. Tumour Biol. 2011;32:317-24.
    • (2011) Tumour Biol , vol.32 , pp. 317-324
    • An, X.1    Ding, P.R.2    Wang, F.H.3    Jiang, W.Q.4    Li, Y.H.5
  • 24
    • 70349110989 scopus 로고    scopus 로고
    • Serum C-reactive protein as a prognostic indicator in patients with oral squamous cell carcinoma
    • 19502100 10.1016/j.oraloncology.2009.03.015 1:CAS:528:DC%2BD1MXhtFGnsb7P
    • Khandavilli SD, Ceallaigh PO, Lloyd CJ, Whitaker R. Serum C-reactive protein as a prognostic indicator in patients with oral squamous cell carcinoma. Oral Oncol. 2009;45:912-4.
    • (2009) Oral Oncol , vol.45 , pp. 912-914
    • Khandavilli, S.D.1    Ceallaigh, P.O.2    Lloyd, C.J.3    Whitaker, R.4
  • 25
    • 84855422114 scopus 로고    scopus 로고
    • Evaluation of immunohistochemical expression of p53, p21, p27, cyclin D1, and Ki67 in oral and oropharyngeal squamous cell carcinoma
    • 21883486 10.1111/j.1600-0714.2011.01071.x
    • Perisanidis C, Perisanidis B, Wrba F, Brandstetter A, El Gazzar S, Papadogeorgakis N, et al. Evaluation of immunohistochemical expression of p53, p21, p27, cyclin D1, and Ki67 in oral and oropharyngeal squamous cell carcinoma. J Oral Pathol Med. 2012;41:40-6.
    • (2012) J Oral Pathol Med , vol.41 , pp. 40-46
    • Perisanidis, C.1    Perisanidis, B.2    Wrba, F.3    Brandstetter, A.4    El Gazzar, S.5    Papadogeorgakis, N.6
  • 27
    • 84857917042 scopus 로고    scopus 로고
    • Inflammation-based prognostic indices in malignant pleural mesothelioma
    • 22307011 10.1097/JTO.0b013e31823f45c1 1:CAS:528:DC%2BC38Xls1Cisbk%3D
    • Pinato DJ, Mauri FA, Ramakrishnan R, Wahab L, Lloyd T, Sharma R. Inflammation-based prognostic indices in malignant pleural mesothelioma. J Thorac Oncol. 2012;7:587-94.
    • (2012) J Thorac Oncol , vol.7 , pp. 587-594
    • Pinato, D.J.1    Mauri, F.A.2    Ramakrishnan, R.3    Wahab, L.4    Lloyd, T.5    Sharma, R.6
  • 28
    • 67649976634 scopus 로고    scopus 로고
    • Functions of gamma C cytokines in immune homeostasis: Current and potential clinical applications
    • 19428306 10.1016/j.clim.2009.03.512 1:CAS:528:DC%2BD1MXotl2gu7s%3D
    • Overwijk WW, Schluns KS. Functions of gamma C cytokines in immune homeostasis: current and potential clinical applications. Clin Immunol. 2009;132:153-65.
    • (2009) Clin Immunol , vol.132 , pp. 153-165
    • Overwijk, W.W.1    Schluns, K.S.2
  • 29
    • 0141483735 scopus 로고    scopus 로고
    • Lymphocyte counts independently predict overall survival in advanced cancer patients: A biomarker for IL-2 immunotherapy
    • 12973028 10.1097/00002371-200309000-00002 1:CAS:528:DC%2BD3sXnt1ansr4%3D
    • Fumagalli LA, Vinke J, Hoff W, Ypma E, Brivio F, Nespoli A. Lymphocyte counts independently predict overall survival in advanced cancer patients: a biomarker for IL-2 immunotherapy. J Immunother. 2003;26:394-402.
    • (2003) J Immunother , vol.26 , pp. 394-402
    • Fumagalli, L.A.1    Vinke, J.2    Hoff, W.3    Ypma, E.4    Brivio, F.5    Nespoli, A.6
  • 30
    • 0035425425 scopus 로고    scopus 로고
    • Factors associated with response to high-dose interleukin-2 in patients with metastatic melanoma
    • 11481353 1:CAS:528:DC%2BD3MXmtlGhurk%3D
    • Phan GQ, Attia P, Steinberg SM, White DE, Rosenberg SA. Factors associated with response to high-dose interleukin-2 in patients with metastatic melanoma. J Clin Oncol. 2001;19:3477-82.
    • (2001) J Clin Oncol , vol.19 , pp. 3477-3482
    • Phan, G.Q.1    Attia, P.2    Steinberg, S.M.3    White, D.E.4    Rosenberg, S.A.5
  • 31
    • 0037428774 scopus 로고    scopus 로고
    • Metastatic renal carcinoma comprehensive prognostic system
    • 12569375 10.1038/sj.bjc.6600768 1:STN:280:DC%2BD3s7gtlyntA%3D%3D
    • Atzpodien J, Royston P, Wandert T, Reitz M. Metastatic renal carcinoma comprehensive prognostic system. Br J Cancer. 2003;88:348-53.
    • (2003) Br J Cancer , vol.88 , pp. 348-353
    • Atzpodien, J.1    Royston, P.2    Wandert, T.3    Reitz, M.4
  • 32
    • 84857376683 scopus 로고    scopus 로고
    • Absolute lymphocyte count is associated with survival in ovarian cancer independent of tumor-infiltrating lymphocytes
    • 22369276 10.1186/1479-5876-10-33 1:CAS:528:DC%2BC38Xlsl2ruro%3D
    • Milne K, Alexander C, Webb JR, Sun W, Dillon K, Kalloger SE, et al. Absolute lymphocyte count is associated with survival in ovarian cancer independent of tumor-infiltrating lymphocytes. J Transl Med. 2012;10:33.
    • (2012) J Transl Med , vol.10 , pp. 33
    • Milne, K.1    Alexander, C.2    Webb, J.R.3    Sun, W.4    Dillon, K.5    Kalloger, S.E.6
  • 33
    • 4143050218 scopus 로고    scopus 로고
    • The potential role of neutrophils in promoting the metastatic phenotype of tumors releasing interleukin-8
    • 15297389 10.1158/1078-0432.CCR-03-0760
    • De Larco JE, Wuertz BR, Furcht LT. The potential role of neutrophils in promoting the metastatic phenotype of tumors releasing interleukin-8. Clin Cancer Res. 2004;10:4895-900.
    • (2004) Clin Cancer Res , vol.10 , pp. 4895-4900
    • De Larco, J.E.1    Wuertz, B.R.2    Furcht, L.T.3
  • 34
    • 80052259764 scopus 로고    scopus 로고
    • Polymorphonuclear granulocytes in human head and neck cancer: Enhanced inflammatory activity, modulation by cancer cells and expansion in advanced disease
    • 10.1002/ijc.25892
    • Trellakis S, Bruderek K, Dumitru CA, Gholaman H, Gu X, Bankfalvi A, et al. Polymorphonuclear granulocytes in human head and neck cancer: enhanced inflammatory activity, modulation by cancer cells and expansion in advanced disease. Int J Cancer. 2010;129:2183-93.
    • (2010) Int J Cancer , vol.129 , pp. 2183-2193
    • Trellakis, S.1    Bruderek, K.2    Dumitru, C.A.3    Gholaman, H.4    Gu, X.5    Bankfalvi, A.6
  • 35
    • 1342287837 scopus 로고    scopus 로고
    • Role of imbalance between neutrophil elastase and alpha 1-antitrypsin in cancer development and progression
    • 15003202 10.1016/S1470-2045(04)01414-7 1:CAS:528:DC%2BD2cXhslSktL4%3D
    • Sun Z, Yang P. Role of imbalance between neutrophil elastase and alpha 1-antitrypsin in cancer development and progression. Lancet Oncol. 2004;5:182-90.
    • (2004) Lancet Oncol , vol.5 , pp. 182-190
    • Sun, Z.1    Yang, P.2
  • 36
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • 15308095 10.1016/j.immuni.2004.07.017 1:CAS:528:DC%2BD2cXnsVKltrY%3D
    • Dunn GP, Old LJ, Schreiber RD. The immunobiology of cancer immunosurveillance and immunoediting. Immunity. 2004;21:137-48.
    • (2004) Immunity , vol.21 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 37
    • 0036023415 scopus 로고    scopus 로고
    • Spontaneous apoptosis of circulating T lymphocytes in patients with head and neck cancer and its clinical importance
    • 12171883
    • Hoffmann TK, Dworacki G, Tsukihiro T, Meidenbauer N, Gooding W, Johnson JT, et al. Spontaneous apoptosis of circulating T lymphocytes in patients with head and neck cancer and its clinical importance. Clin Cancer Res. 2002;8:2553-62.
    • (2002) Clin Cancer Res , vol.8 , pp. 2553-2562
    • Hoffmann, T.K.1    Dworacki, G.2    Tsukihiro, T.3    Meidenbauer, N.4    Gooding, W.5    Johnson, J.T.6
  • 38
    • 64549132600 scopus 로고    scopus 로고
    • The application of high-dose interleukin-2 for metastatic renal cell carcinoma
    • 19148594 10.1007/s12032-008-9152-1
    • McDermott DF. The application of high-dose interleukin-2 for metastatic renal cell carcinoma. Med Oncol. 2009;26(Suppl 1):13-7.
    • (2009) Med Oncol , vol.26 , Issue.SUPPL. 1 , pp. 13-17
    • McDermott, D.F.1
  • 39
    • 84856679198 scopus 로고    scopus 로고
    • Usefulness of the neutrophil-to-lymphocyte ratio in predicting short- and long-term mortality in breast cancer patients
    • 21638095 10.1245/s10434-011-1814-0
    • Azab B, Bhatt VR, Phookan J, Murukutla S, Kohn N, Terjanian T, et al. Usefulness of the neutrophil-to-lymphocyte ratio in predicting short- and long-term mortality in breast cancer patients. Ann Surg Oncol. 2012;19:217-24.
    • (2012) Ann Surg Oncol , vol.19 , pp. 217-224
    • Azab, B.1    Bhatt, V.R.2    Phookan, J.3    Murukutla, S.4    Kohn, N.5    Terjanian, T.6
  • 40
    • 84868007211 scopus 로고    scopus 로고
    • The long-term predictive value of the neutrophil-to-lymphocyte ratio in Type 2 diabetic patients presenting with acute myocardial infarction
    • Lee GK, Lee LC, Chong E, Lee CH, Teo SG, Chia BL et al. The long-term predictive value of the neutrophil-to-lymphocyte ratio in Type 2 diabetic patients presenting with acute myocardial infarction. QJM. 2012.
    • (2012) QJM
    • Lee, G.K.1    Lee, L.C.2    Chong, E.3    Lee, C.H.4    Teo, S.G.5    Chia, B.L.6
  • 41
    • 38749138439 scopus 로고    scopus 로고
    • Neoadjuvant concurrent radiochemotherapy followed by surgery in advanced oral squamous cell carcinoma (OSCC): A retrospective analysis of 207 patients
    • 17350327 10.1016/j.oraloncology.2007.01.006 1:CAS:528: DC%2BD1cXhsVKhtrk%3D
    • Freier K, Engel M, Lindel K, Flechtenmacher C, Muhling J, Hassfeld S, et al. Neoadjuvant concurrent radiochemotherapy followed by surgery in advanced oral squamous cell carcinoma (OSCC): a retrospective analysis of 207 patients. Oral Oncol. 2008;44:116-23.
    • (2008) Oral Oncol , vol.44 , pp. 116-123
    • Freier, K.1    Engel, M.2    Lindel, K.3    Flechtenmacher, C.4    Muhling, J.5    Hassfeld, S.6
  • 42
    • 65649106519 scopus 로고    scopus 로고
    • Outcome and histopathologic regression in oral squamous cell carcinoma after preoperative radiochemotherapy
    • 19440668 10.1007/s00066-009-1914-y
    • Driemel O, Ettl T, Kolbl O, Reichert TE, Dresp BV, Reuther J, et al. Outcome and histopathologic regression in oral squamous cell carcinoma after preoperative radiochemotherapy. Strahlenther Onkol. 2009;185:296-302.
    • (2009) Strahlenther Onkol , vol.185 , pp. 296-302
    • Driemel, O.1    Ettl, T.2    Kolbl, O.3    Reichert, T.E.4    Dresp, B.V.5    Reuther, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.