Error-prone polymerase activity causes multinucleotide mutations in humans

Genome Research

Volumn 24, Issue 9, 2014, Pages 1445-1454

  Harris, Kelley ^a   Nielsen, Rasmus ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; NUCLEOTIDE; DNA DIRECTED DNA POLYMERASE; DNA POLYMERASE ZETA;

ALLELE; ARTICLE; DIPLOIDY; DNA REPLICATION; DNA SEQUENCE; EFFECTIVE POPULATION SIZE; ENZYME ACTIVITY; EXCISION REPAIR; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HETEROZYGOTE; HUMAN; HUMAN GENOME; MUTATION RATE; NATURAL SELECTION; POINT MUTATION; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC HYPERMUTATION; ANIMAL; BIOLOGICAL MODEL; GENE FREQUENCY; GENETICS; MUTATION; PAN TROGLODYTES; RHESUS MONKEY;

ANIMALS; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; GENE FREQUENCY; GENOME, HUMAN; HUMANS; MACACA MULATTA; MODELS, GENETIC; MUTATION; PAN TROGLODYTES; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84907225774     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.170696.113     Document Type: Article

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