-
1
-
-
77952363301
-
Glutamate receptor ion channels: Structure, regulation, and function
-
Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, et al. (2010) Glutamate receptor ion channels: structure, regulation, and function. Pharmacol Rev 62: 405-496. DOI: 10.1124/pr.109.002451.
-
(2010)
Pharmacol Rev
, vol.62
, pp. 405-496
-
-
Traynelis, S.F.1
Wollmuth, L.P.2
McBain, C.J.3
Menniti, F.S.4
Vance, K.M.5
-
2
-
-
0002524565
-
-
In: Lodge D, Danysz W, Parsons CG, editors. Johnson City, TN: F.P. Graham Publishing Co
-
Löscher W, Rogawski MA (2002) Epilepsy. In: Lodge D, Danysz W, Parsons CG, editors. Ionotropic glutamate receptors as therapeutic targets. Johnson City, TN: F.P. Graham Publishing Co. 91-132.
-
(2002)
Epilepsy Ionotropic Glutamate Receptors As Therapeutic Targets
, pp. 91-132
-
-
Löscher, W.1
Rogawski, M.A.2
-
3
-
-
84875077324
-
AMPA receptors as a molecular target in epilepsy therapy
-
Rogawski MA (2013) AMPA receptors as a molecular target in epilepsy therapy. Acta Neurol Scand Suppl 2013;(197): 9-18. DOI: 10.1111/ane.12099.
-
(2013)
Acta Neurol Scand Suppl
, vol.2013
, Issue.197
, pp. 9-18
-
-
Rogawski, M.A.1
-
4
-
-
0025117827
-
2,3- Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: A neuroprotectant for cerebral ischemia
-
Sheardown MJ, Nielsen EO, Hansen AJ, Jacobsen P, Honoré T (1990) 2,3- Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia. Science 247: 571-574. DOI: 10.1126/science.2154034.
-
(1990)
Science
, vol.247
, pp. 571-574
-
-
Sheardown, M.J.1
Nielsen, E.O.2
Hansen, A.J.3
Jacobsen, P.4
Honoré, T.5
-
5
-
-
0037448433
-
Competitive antagonism of AMPA receptors by ligands of different classes: Crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX
-
Hogner A, Greenwood JR, Liljefors T, Lunn ML, Egebjerg J, et al. (2003) Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX. J Med Chem 46: 214-21. DOI: 10.1021/jm020989v.
-
(2003)
J Med Chem
, vol.46
, pp. 214-221
-
-
Hogner, A.1
Greenwood, J.R.2
Liljefors, T.3
Lunn, M.L.4
Egebjerg, J.5
-
6
-
-
0027404879
-
GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses
-
Donevan SD, Rogawski MA (1993) GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses. Neuron 10: 51-59. DOI: 10.1016/0896-6273(93)90241-I.
-
(1993)
Neuron
, vol.10
, pp. 51-59
-
-
Donevan, S.D.1
Rogawski, M.A.2
-
7
-
-
0036247871
-
Non-competitive AMPA antagonists of 2,3- benzodiazepine type
-
Sólyom S, Tarnawa I (2002) Non-competitive AMPA antagonists of 2,3- benzodiazepine type. Curr Pharm Des 8: 913-939. DOI: 10.2174/ 1381612024607081.
-
(2002)
Curr Pharm des
, vol.8
, pp. 913-939
-
-
Sólyom, S.1
Tarnawa, I.2
-
8
-
-
80051723012
-
Mechanism of inhibition of the GluA2 AMPA receptor channel opening: The role of 4-methyl versus 4- carbonyl group on the diazepine ring of 2,3-benzodiazepine derivatives
-
Ritz M, Wang C, Micale N, Ettari R, Niu L (2011) Mechanism of inhibition of the GluA2 AMPA receptor channel opening: the role of 4-methyl versus 4- carbonyl group on the diazepine ring of 2,3-benzodiazepine derivatives. ACS Chem Neurosci 2: 506-513. DOI: 10.1021/cn200033j.
-
(2011)
ACS Chem Neurosci
, vol.2
, pp. 506-513
-
-
Ritz, M.1
Wang, C.2
Micale, N.3
Ettari, R.4
Niu, L.5
-
9
-
-
84894468158
-
Mechanism and site of inhibition of AMPA receptors: Pairing a thiadiazole with a 2,3-benzodiazepine scaffold
-
Wang C, Han Y, Wu A, Sólyom S, Niu L (2013) Mechanism and site of inhibition of AMPA receptors: pairing a thiadiazole with a 2,3-benzodiazepine scaffold. ACS Chem Neurosci 5: 138-147. DOI: 10.1021/cn400193u.
-
(2013)
ACS Chem Neurosci
, vol.5
, pp. 138-147
-
-
Wang, C.1
Han, Y.2
Wu, A.3
Sólyom, S.4
Niu, L.5
-
10
-
-
0036166553
-
Functional characterization of CP-465,022, a selective, noncompetitive AMPA receptor antagonist
-
Lazzaro JT, Paternain AV, Lerma J, Chenard BL, Ewing FE, et al. (2002) Functional characterization of CP-465,022, a selective, noncompetitive AMPA receptor antagonist. Neuropharmacology 42: 143-153. DOI: 10.1016/S0028- 3908(01)00170-8.
-
(2002)
Neuropharmacology
, vol.42
, pp. 143-153
-
-
Lazzaro, J.T.1
Paternain, A.V.2
Lerma, J.3
Chenard, B.L.4
Ewing, F.E.5
-
11
-
-
26944451291
-
Molecular mechanism of AMPA receptor noncompetitive antagonism
-
Balannik V, Menniti FS, Paternain AV, Lerma J, Stern-Bach Y (2005) Molecular mechanism of AMPA receptor noncompetitive antagonism. Neuron 48: 279-288. DOI: 10.1016/j.neuron.2005.09.024.
-
(2005)
Neuron
, vol.48
, pp. 279-288
-
-
Balannik, V.1
Menniti, F.S.2
Paternain, A.V.3
Lerma, J.4
Stern-Bach, Y.5
-
12
-
-
84881128534
-
Efficacy and safety of adjunctive perampanel for the treatment of refractory partial seizures: A pooled analysis of three phase III studies
-
Steinhoff BJ, Ben-Menachem E, Ryvlin P, Shorvon S, Kramer L, et al. (2103) Efficacy and safety of adjunctive perampanel for the treatment of refractory partial seizures: a pooled analysis of three phase III studies. Epilepsia 54: 1481-1489. DOI: 10.1111/epi.12212.
-
(2103)
Epilepsia
, vol.54
, pp. 1481-1489
-
-
Steinhoff, B.J.1
Ben-Menachem, E.2
Ryvlin, P.3
Shorvon, S.4
Kramer, L.5
-
13
-
-
84893007103
-
Perampanel: A selective AMPA antagonist for treating seizures
-
Krauss GL (2013) Perampanel: a selective AMPA antagonist for treating seizures. Epilepsy Curr 13: 269-272. DOI: 10.5698/1535-7597-13.6.269.
-
(2013)
Epilepsy Curr
, vol.13
, pp. 269-272
-
-
Krauss, G.L.1
-
14
-
-
84870989558
-
Discovery of 2-(2- oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile (perampanel): A novel, noncompetitive a-amino-3-hydroxy-5-methyl-4-isoxazolepropanoic acid (AMPA) receptor antagonist
-
Hibi S, Ueno K, Nagato S, Kawano K, Ito K, et al. (2012) Discovery of 2-(2- oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile (perampanel): a novel, noncompetitive a-amino-3-hydroxy-5-methyl-4-isoxazolepropanoic acid (AMPA) receptor antagonist. J Med Chem 55: 10584-11600. DOI: 10.1021/jm301268u.
-
(2012)
J Med Chem
, vol.55
, pp. 10584-11600
-
-
Hibi, S.1
Ueno, K.2
Nagato, S.3
Kawano, K.4
Ito, K.5
-
15
-
-
79959970405
-
Perampanel: A novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy
-
Hanada T, Hashizume Y, Tokuhara N, Takenaka O, Kohmura N, et al. (2011) Perampanel: a novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy. Epilepsia 52: 1331- 1140. DOI: 10.1111/j.1528-1167.2011.03109.x.
-
(2011)
Epilepsia
, vol.52
, pp. 1331-1140
-
-
Hanada, T.1
Hashizume, Y.2
Tokuhara, N.3
Takenaka, O.4
Kohmura, N.5
-
16
-
-
84865793663
-
A novel anti-epileptic agent, perampanel, selectively inhibits AMPA receptormediated synaptic transmission in the hippocampus
-
Ceolin L, Bortolotto ZA, Bannister N, Collingridge GL, Lodge D, et al. (2012) A novel anti-epileptic agent, perampanel, selectively inhibits AMPA receptormediated synaptic transmission in the hippocampus. Neurochem Int 61: 517-522. DOI: 10.1016/j.neuint.2012.02.035.
-
(2012)
Neurochem Int
, vol.61
, pp. 517-522
-
-
Ceolin, L.1
Bortolotto, Z.A.2
Bannister, N.3
Collingridge, G.L.4
Lodge, D.5
-
17
-
-
84876036491
-
Pharmacological profile of perampanel: A novel, non-competitive selective AMPA receptor antagonist
-
Abstract
-
Tokuhara N, Hatakeyama S, Amino H, Hanada T, Nishizawa Y (2008) Pharmacological profile of perampanel: a novel, non-competitive selective AMPA receptor antagonist. J Neurol 255: 175 (Abstract P706). DOI: 10.1007/ s00415-008-2001-5.
-
(2008)
J Neurol
, vol.255
, pp. 175
-
-
Tokuhara, N.1
Hatakeyama, S.2
Amino, H.3
Hanada, T.4
Nishizawa, Y.5
-
18
-
-
43449130057
-
NS21: Redefined and modified supplement B27 for neuronal cultures
-
Chen Y, Stevens B, Chang J, Milbrandt J, Barres BA, et al. (2008) NS21: redefined and modified supplement B27 for neuronal cultures. J Neurosci Methods 171: 239-247. DOI: 10.1016/j.jneumeth.2008.03.013.
-
(2008)
J Neurosci Methods
, vol.171
, pp. 239-247
-
-
Chen, Y.1
Stevens, B.2
Chang, J.3
Milbrandt, J.4
Barres, B.A.5
-
19
-
-
0027145163
-
Functional kainateselective glutamate receptors in cultured hippocampal neurons
-
Lerma J, Paternain AV, Naranjo JR, Mellström B (1993) Functional kainateselective glutamate receptors in cultured hippocampal neurons. Proc Natl Acad Sci USA 90: 11688-11692.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11688-11692
-
-
Lerma, J.1
Paternain, A.V.2
Naranjo, J.R.3
Mellström, B.4
-
20
-
-
0027228511
-
Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate
-
Patneau DK, Vyklicky L Jr, Mayer ML (1993) Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate. J Neurosci 13: 3496-3509.
-
(1993)
J Neurosci
, vol.13
, pp. 3496-3509
-
-
Patneau, D.K.1
Vyklicky, L.2
Mayer, M.L.3
-
21
-
-
0028836733
-
Selective antagonism of AMPA receptors unmasks kainate receptor-mediated responses in hippocampal neurons
-
Paternain AV, Morales M, Lerma J (1995) Selective antagonism of AMPA receptors unmasks kainate receptor-mediated responses in hippocampal neurons. Neuron 14: 185-189. DOI:10.1016/0896-6273(95)90253-8.
-
(1995)
Neuron
, vol.14
, pp. 185-189
-
-
Paternain, A.V.1
Morales, M.2
Lerma, J.3
-
22
-
-
0032191104
-
A point mutation in the glutamate binding site blocks desensitization of AMPA receptors
-
Stern-Bach Y, Russo S, Neuman M, Rosenmund C (1998) A point mutation in the glutamate binding site blocks desensitization of AMPA receptors. Neuron 21: 907-918. DOI: 10.1016/S0896-6273(00)80605-4.
-
(1998)
Neuron
, vol.21
, pp. 907-918
-
-
Stern-Bach, Y.1
Russo, S.2
Neuman, M.3
Rosenmund, C.4
-
23
-
-
0033636314
-
Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: Crystal structures of the GluR2 ligand binding core
-
Armstrong N, Gouaux E (2000) Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron 28: 165-181. DOI: 10.1016/S0896-6273(00)00094-5.
-
(2000)
Neuron
, vol.28
, pp. 165-181
-
-
Armstrong, N.1
Gouaux, E.2
-
24
-
-
0028321986
-
Comparative patch clamp studies on the kinetics and selectivity of glutamate receptor antagonism by 2,3-dihydroxy-6- nitro-7-sulfamoyl-benzo(F) quinoxaline (NBQX) and 1-(4-amino-phenyl)-4-methyl- 7,8-methyl-endioxyl-5H-2,3-benzodiaze pine (GYKI 52466)
-
Parsons CG, Gruner R, Rozental J (1994) Comparative patch clamp studies on the kinetics and selectivity of glutamate receptor antagonism by 2,3-dihydroxy-6- nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) and 1-(4-amino-phenyl)-4-methyl- 7,8-methyl-endioxyl-5H-2,3-benzodiaze pine (GYKI 52466). Neuropharmacology 33: 589-604. DOI: 10.1016/0028-3908(94)90163-5.
-
(1994)
Neuropharmacology
, vol.33
, pp. 589-604
-
-
Parsons, C.G.1
Gruner, R.2
Rozental, J.3
-
25
-
-
0032483107
-
Allosteric regulation of a-amino-3-hydroxy- 5-methyl-4-isoxazole-propionate receptors by thiocyanate and cyclothiazide at a common modulatory site distinct from that of 2,3-benzodiazepines
-
Donevan SD, Rogawski MA (1998) Allosteric regulation of a-amino-3-hydroxy- 5-methyl-4-isoxazole-propionate receptors by thiocyanate and cyclothiazide at a common modulatory site distinct from that of 2,3-benzodiazepines. Neuroscience 87: 615-629. DOI: 10.1016/S0306-4522(98)00109-2.
-
(1998)
Neuroscience
, vol.87
, pp. 615-629
-
-
Donevan, S.D.1
Rogawski, M.A.2
|