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Volumn 7, Issue , 2014, Pages 1583-1591

Mir-206 functions as a tumor suppressor and directly targets K-Ras in human oral squamous cell carcinoma

Author keywords

Apoptosis; Invasion; MiR 206; Oral squamous cell carcinoma; Prognosis; Proliferation

Indexed keywords

K RAS PROTEIN; MICRORNA; MICRORNA 206; UNCLASSIFIED DRUG;

EID: 84907219702     PISSN: None     EISSN: 11786930     Source Type: Journal    
DOI: 10.2147/OTT.S67624     Document Type: Article
Times cited : (20)

References (40)
  • 1
    • 77958600637 scopus 로고    scopus 로고
    • Trends in the epidemiology of oral squamous cell carcinoma in Western UP: An institutional study
    • Sharma P, Saxena S, Aggarwal P. Trends in the epidemiology of oral squamous cell carcinoma in Western UP: an institutional study. Indian J Dent Res. 2010;21(3):316–319.
    • (2010) Indian J Dent Res. , vol.21 , Issue.3 , pp. 316-319
    • Sharma, P.1    Saxena, S.2    Aggarwal, P.3
  • 4
    • 84868517441 scopus 로고    scopus 로고
    • Clinical significance of eryth-ropoietin receptor expression in oral squamous cell carcinoma
    • Lin YT, Chuang HC, Chen CH, et al. Clinical significance of eryth-ropoietin receptor expression in oral squamous cell carcinoma. BMC Cancer. 2012;12:194.
    • (2012) BMC Cancer , vol.12 , pp. 194
    • Lin, Y.T.1    Chuang, H.C.2    Chen, C.H.3
  • 5
    • 84863688212 scopus 로고    scopus 로고
    • MicroRNAs in health and disease – basic science and clinical applications
    • Osman A. MicroRNAs in health and disease – basic science and clinical applications. Clin Lab. 2012;58(5–6):393–402.
    • (2012) Clin Lab. , vol.58 , Issue.5-6 , pp. 393-402
    • Osman, A.1
  • 6
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel D P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116(2):281–297.
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 7
    • 33846188098 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumor suppressors
    • Zhang B, Pan X, Cobb G P, Anderson TA. MicroRNAs as oncogenes and tumor suppressors. Dev Biol. 2007;302(1):1–12.
    • (2007) Dev Biol. , vol.302 , Issue.1 , pp. 1-12
    • Zhang, B.1    Pan, X.2    Cobb, G.P.3    Anderson, T.A.4
  • 8
    • 84869083625 scopus 로고    scopus 로고
    • MicroRNAs miR-371-3 in serum as diagnostic tools in the management of testicular germ cell tumours
    • Dieckmann K P, Spiekermann M, Balks T, et al. MicroRNAs miR-371-3 in serum as diagnostic tools in the management of testicular germ cell tumours. Br J Cancer. 2012;107(10):1754–1760.
    • (2012) Br J Cancer , vol.107 , Issue.10 , pp. 1754-1760
    • Dieckmann, K.P.1    Spiekermann, M.2    Balks, T.3
  • 9
    • 84867048400 scopus 로고    scopus 로고
    • The clinical significance of miR-148a as a predictive biomarker in patients with advanced colorectal cancer
    • Takahashi M, Cuatrecasas M, Balaguer F, et al. The clinical significance of miR-148a as a predictive biomarker in patients with advanced colorectal cancer. PLoS One. 2012;7(10):e46684.
    • (2012) PLoS One. , vol.7 , Issue.10
    • Takahashi, M.1    Cuatrecasas, M.2    Balaguer, F.3
  • 10
    • 23844555119 scopus 로고    scopus 로고
    • MicroRNA gene expression deregulation in human breast cancer
    • Iorio M V, Ferracin M, Liu CG, et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 2005;65(16): 7065–7070.
    • (2005) Cancer Res. , vol.65 , Issue.16 , pp. 7065-7070
    • Iorio, M.V.1    Ferracin, M.2    Liu, C.G.3
  • 11
    • 78650116773 scopus 로고    scopus 로고
    • MicroRNA-206 is associated with invasion and metastasis of lung cancer
    • Wang X, Ling C, Bai Y, Zhao J. MicroRNA-206 is associated with invasion and metastasis of lung cancer. Anat Rec (Hoboken). 2011;294(1): 88–92.
    • (2011) Anat Rec (Hoboken) , vol.294 , Issue.1 , pp. 88-92
    • Wang, X.1    Ling, C.2    Bai, Y.3    Zhao, J.4
  • 12
    • 84875252943 scopus 로고    scopus 로고
    • MiR-206 inhibits gastric cancer proliferation in part by repressing cyclinD2
    • Zhang L, Liu X, Jin H, et al. MiR-206 inhibits gastric cancer proliferation in part by repressing cyclinD2. Cancer Lett. 2013;332(1): 94–101.
    • (2013) Cancer Lett , vol.332 , Issue.1 , pp. 94-101
    • Zhang, L.1    Liu, X.2    Jin, H.3
  • 13
    • 84888882715 scopus 로고    scopus 로고
    • A role for low-abundance miRNAs in colon cancer: The miR-206/Kruppel-like factor 4 (KLF4) axis
    • Parasramka MA, Dashwood WM, Wang R, et al. A role for low-abundance miRNAs in colon cancer: the miR-206/Kruppel-like factor 4 (KLF4) axis. Clin Epigenetics. 2012;4(1):16.
    • (2012) Clin Epigenetics , vol.4 , Issue.1 , pp. 16
    • Parasramka, M.A.1    Dashwood, W.M.2    Wang, R.3
  • 14
    • 78651253572 scopus 로고    scopus 로고
    • Integrated profiling of microRNAs and mRNAs: MicroRNAs located on Xq27.3 associate with clear cell renal cell carcinoma
    • Zhou L, Chen J, Li Z, et al. Integrated profiling of microRNAs and mRNAs: microRNAs located on Xq27.3 associate with clear cell renal cell carcinoma. PLoS One. 2010;5(12):e15224.
    • (2010) PLoS One , vol.5 , Issue.12
    • Zhou, L.1    Chen, J.2    Li, Z.3
  • 15
    • 82355191732 scopus 로고    scopus 로고
    • Expression of the tumor suppressor miR-206 is associated with cellular proliferative inhibition and impairs invasion in ERα-positive endometrioid adenocarcinoma
    • Chen X, Ya n Q, Li S, et al. Expression of the tumor suppressor miR-206 is associated with cellular proliferative inhibition and impairs invasion in ERα-positive endometrioid adenocarcinoma. Cancer Lett. 2012;314(1):41–53.
    • (2012) Cancer Lett , vol.314 , Issue.1 , pp. 41-53
    • Chen, X.1    Ya N, Q.2    Li, S.3
  • 16
    • 84859903844 scopus 로고    scopus 로고
    • MiR-206 regulates neural cells proliferation and apoptosis via Otx2
    • Wang R, Hu Y, Song G, et al. MiR-206 regulates neural cells proliferation and apoptosis via Otx2. Cell Physiol Biochem. 2012;29(3–4):381–390.
    • (2012) Cell Physiol Biochem , vol.29 , Issue.3-4 , pp. 381-390
    • Wang, R.1    Hu, Y.2    Song, G.3
  • 17
    • 77953289017 scopus 로고    scopus 로고
    • MicroRNA-206 expression levels correlate with clinical behaviour of rhabdomyosarcomas
    • Missiaglia E, Shepherd CJ, Patel S, et al. MicroRNA-206 expression levels correlate with clinical behaviour of rhabdomyosarcomas. Br J Cancer. 2010;102(12):1769–1777.
    • (2010) Br J Cancer , vol.102 , Issue.12 , pp. 1769-1777
    • Missiaglia, E.1    Shepherd, C.J.2    Patel, S.3
  • 18
    • 84882735052 scopus 로고    scopus 로고
    • Roles of microRNA-206 in osteo-sarcoma pathogenesis and progression
    • Bao Y P, Yi Y, Peng LL, et al. Roles of microRNA-206 in osteo-sarcoma pathogenesis and progression. Asian Pac J Cancer Prev. 2013;14(6):3751–3755.
    • (2013) Asian Pac J Cancer Prev , vol.14 , Issue.6 , pp. 3751-3755
    • Bao, Y.P.1    Yi, Y.2    Peng, L.L.3
  • 19
    • 84879974093 scopus 로고    scopus 로고
    • Downregulation of microRNA-206 is a potent prognostic marker for patients with gastric cancer
    • Yang Q, Zhang C, Huang B, et al. Downregulation of microRNA-206 is a potent prognostic marker for patients with gastric cancer. Eur J Gastroenterol Hepatol. 2013;25(8):953–957.
    • (2013) Eur J Gastroenterol Hepatol , vol.25 , Issue.8 , pp. 953-957
    • Yang, Q.1    Zhang, C.2    Huang, B.3
  • 20
    • 84857144859 scopus 로고    scopus 로고
    • Stage-dependent differential expression of microRNAs in colorectal cancer: Potential role as markers of metastatic disease
    • Vickers MM, Bar J, Gorn-Hondermann I, et al. Stage-dependent differential expression of microRNAs in colorectal cancer: potential role as markers of metastatic disease. Clin Exp Metastasis. 2012;29(2): 123–132.
    • (2012) Clin Exp Metastasis , vol.29 , Issue.2 , pp. 123-132
    • Vickers, M.M.1    Bar, J.2    Gorn-Hondermann, I.3
  • 21
    • 0020132123 scopus 로고
    • Isolation of a transforming sequence from a human bladder carcinoma cell line
    • Shih C, Weinberg RA. Isolation of a transforming sequence from a human bladder carcinoma cell line. Cell. 1982;29(1):161–169.
    • (1982) Cell , vol.29 , Issue.1 , pp. 161-169
    • Shih, C.1    Weinberg, R.A.2
  • 22
    • 3442883361 scopus 로고    scopus 로고
    • Inducible activation of oncogenic K-ras results in tumor formation in the oral cavity
    • Caulin C, Nguyen T, Longley MA, Zhou Z, Wang XJ, Roop DR. Inducible activation of oncogenic K-ras results in tumor formation in the oral cavity. Cancer Res. 2004;64(15):5054–5058.
    • (2004) Cancer Res , vol.64 , Issue.15 , pp. 5054-5058
    • Caulin, C.1    Nguyen, T.2    Longley, M.A.3    Zhou, Z.4    Wang, X.J.5    Roop, D.R.6
  • 23
    • 0034128434 scopus 로고    scopus 로고
    • Anti-K-ras ribozyme induces growth inhibition and increased chemosensitivity in human colon cancer cells
    • Funato T, Ishii T, Kambe M, Scanlon KJ, Sasaki T. Anti-K-ras ribozyme induces growth inhibition and increased chemosensitivity in human colon cancer cells. Cancer Gene Ther. 2000;7(3):495–500.
    • (2000) Cancer Gene Ther , vol.7 , Issue.3 , pp. 495-500
    • Funato, T.1    Ishii, T.2    Kambe, M.3    Scanlon, K.J.4    Sasaki, T.5
  • 24
    • 22944447177 scopus 로고    scopus 로고
    • Molecular consequences of silencing mutant K-ras in pancreatic cancer cells: Justifcation for K-ras-directed therapy
    • Fleming JB, Shen GL, Holloway SE, Davis M, Brekken RA. Molecular consequences of silencing mutant K-ras in pancreatic cancer cells: justifcation for K-ras-directed therapy. Mol Cancer Res. 2005;3(7):413–423.
    • (2005) Mol Cancer Res , vol.3 , Issue.7 , pp. 413-423
    • Fleming, J.B.1    Shen, G.L.2    Holloway, S.E.3    Davis, M.4    Brekken, R.A.5
  • 25
    • 79151484006 scopus 로고    scopus 로고
    • MiR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras
    • Shin KH, Bae SD, Hong HS, Kim RH, Kang MK, Park NH. MiR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras. Biochem Biophys Res Commun. 2011;404(4):896–902.
    • (2011) Biochem Biophys Res Commun , vol.404 , Issue.4 , pp. 896-902
    • Shin, K.H.1    Bae, S.D.2    Hong, H.S.3    Kim, R.H.4    Kang, M.K.5    Park, N.H.6
  • 26
    • 77955033963 scopus 로고    scopus 로고
    • MiRNA-96 suppresses KRAS and functions as a tumor suppressor gene in pancreatic cancer
    • Yu S, Lu Z, Liu C, et al. MiRNA-96 suppresses KRAS and functions as a tumor suppressor gene in pancreatic cancer. Cancer Res. 2010;70(14):6015–6025.
    • (2010) Cancer Res , vol.70 , Issue.14 , pp. 6015-6025
    • Yu, S.1    Lu, Z.2    Liu, C.3
  • 27
    • 62249137047 scopus 로고    scopus 로고
    • Role of miR-143 targeting KRAS in colorectal tumorigenesis
    • Chen X, Guo X, Zhang H, et al. Role of miR-143 targeting KRAS in colorectal tumorigenesis. Oncogene. 2009;28(10):1385–1392.
    • (2009) Oncogene , vol.28 , Issue.10 , pp. 1385-1392
    • Chen, X.1    Guo, X.2    Zhang, H.3
  • 28
    • 77957762440 scopus 로고    scopus 로고
    • The miR-217 microRNA functions as a potential tumor suppressor in pancreatic ductal adenocarcinoma by targeting KRAS
    • Zhao WG, Yu SN, Lu ZH, Ma YH, Gu YM, Chen J. The miR-217 microRNA functions as a potential tumor suppressor in pancreatic ductal adenocarcinoma by targeting KRAS. Carcinogenesis. 2010;31(10):1726–1733.
    • (2010) Carcinogenesis , vol.31 , Issue.10 , pp. 1726-1733
    • Zhao, W.G.1    Yu, S.N.2    Lu, Z.H.3    Ma, Y.H.4    Gu, Y.M.5    Chen, J.6
  • 29
    • 70449124423 scopus 로고    scopus 로고
    • Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines
    • Leivonen SK, Makela R, Ostling P, et al. Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines. Oncogene. 2009;28(44):3926–3936.
    • (2009) Oncogene , vol.28 , Issue.44 , pp. 3926-3936
    • Leivonen, S.K.1    Makela, R.2    Ostling, P.3
  • 30
    • 68849118992 scopus 로고    scopus 로고
    • The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotrans-planted mice by promoting myogenic differentiation
    • Taulli R, Bersani F, Foglizzo V, et al. The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotrans-planted mice by promoting myogenic differentiation. J Clin Invest. 2009;119(8):2366–2378.
    • (2009) J Clin Invest , vol.119 , Issue.8 , pp. 2366-2378
    • Taulli, R.1    Bersani, F.2    Foglizzo, V.3
  • 31
    • 84891757313 scopus 로고    scopus 로고
    • S-1-based combination therapy vs S-1 monotherapy in advanced gastric cancer: A meta-analysis
    • Liu GF, Tang D, Li P, et al. S-1-based combination therapy vs S-1 monotherapy in advanced gastric cancer: a meta-analysis. World J Gastroenterol. 2014;20(1):310–318.
    • (2014) World J Gastroenterol , vol.20 , Issue.1 , pp. 310-318
    • Liu, G.F.1    Tang, D.2    Li, P.3
  • 32
    • 78751689243 scopus 로고    scopus 로고
    • MiR-206 and -486 induce myoblast differentiation by downregulating Pax7
    • Dey BK, Gagan J, Dutta A. MiR-206 and -486 induce myoblast differentiation by downregulating Pax7. Mol Cell Biol. 2011;31(1):203–214.
    • (2011) Mol Cell Biol , vol.31 , Issue.1 , pp. 203-214
    • Dey, B.K.1    Gagan, J.2    Dutta, A.3
  • 33
    • 70450225266 scopus 로고    scopus 로고
    • MicroRNA-206 targets notch3, activates apoptosis, and inhibits tumor cell migration and focus formation
    • Song G, Zhang Y, Wang L. MicroRNA-206 targets notch3, activates apoptosis, and inhibits tumor cell migration and focus formation. J Biol Chem. 2009;284(46):31921–31927.
    • (2009) J Biol Chem , vol.284 , Issue.46 , pp. 31921-31927
    • Song, G.1    Zhang, Y.2    Wang, L.3
  • 34
    • 48549099077 scopus 로고    scopus 로고
    • MiR-206 expression is down-regulated in estrogen receptor α-positive human breast cancer
    • Kondo N, Toyama T, Sugiura H, Fujii Y, Yamashita H. MiR-206 expression is down-regulated in estrogen receptor α-positive human breast cancer. Cancer Res. 2008;68(13):5004–5008.
    • (2008) Cancer Res , vol.68 , Issue.13 , pp. 5004-5008
    • Kondo, N.1    Toyama, T.2    Sugiura, H.3    Fujii, Y.4    Yamashita, H.5
  • 35
    • 83055162537 scopus 로고    scopus 로고
    • Down-regulation of miR-206 promotes proliferation and invasion of laryngeal cancer by regulating VEGF expression
    • Zhang T, Liu M, Wang C, Lin C, Sun Y, Jin D. Down-regulation of miR-206 promotes proliferation and invasion of laryngeal cancer by regulating VEGF expression. Anticancer Res. 2011;31(11):3859–3863.
    • (2011) Anticancer Res , vol.31 , Issue.11 , pp. 3859-3863
    • Zhang, T.1    Liu, M.2    Wang, C.3    Lin, C.4    Sun, Y.5    Jin, D.6
  • 36
    • 66749160812 scopus 로고    scopus 로고
    • The miR-18a* microRNA functions as a potential tumor suppressor by targeting on K-Ras
    • Tsang WP, Kwok TT. The miR-18a* microRNA functions as a potential tumor suppressor by targeting on K-Ras. Carcinogenesis. 2009;30(6):953–959.
    • (2009) Carcinogenesis , vol.30 , Issue.6 , pp. 953-959
    • Tsang, W.P.1    Kwok, T.T.2
  • 38
    • 20944450160 scopus 로고    scopus 로고
    • Combinatorial microRNA target predictions
    • Krek A, Grun D, Poy MN, et al. Combinatorial microRNA target predictions. Nat Genet. 2005;37(5):495–500.
    • (2005) Nat Genet. , vol.37 , Issue.5 , pp. 495-500
    • Krek, A.1    Grun, D.2    Poy, M.N.3
  • 39
    • 70849130151 scopus 로고    scopus 로고
    • VEGF and VEGFRs expression in oral squamous cell carcinoma
    • Margaritescu C, Pirici D, Simionescu C, et al. VEGF and VEGFRs expression in oral squamous cell carcinoma. Rom J Morphol Embryol. 2009;50(4):527–548.
    • (2009) Rom J Morphol Embryol. , vol.50 , Issue.4 , pp. 527-548
    • Margaritescu, C.1    Pirici, D.2    Simionescu, C.3
  • 40
    • 84907200207 scopus 로고    scopus 로고
    • The expression and significance of the Notch signaling pathway molecules in tongue squamous cell carcinoma
    • Chinese
    • Zhang T, Liu H, Liang Y, et al. The expression and significance of the Notch signaling pathway molecules in tongue squamous cell carcinoma. Hua Xi Kou Qiang Yi Xue Za Zhi. 2013;31(3):303–309. Chinese.
    • (2013) Hua Xi Kou Qiang Yi Xue Za Zhi. , vol.31 , Issue.3 , pp. 303-309
    • Zhang, T.1    Liu, H.2    Liang, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.