-
1
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P, Jain RK (2000) Angiogenesis in cancer and other diseases. Nature 407: 249-257.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
2
-
-
33646816714
-
Neovascularization in human atherosclerosis
-
Moreno PR, Purushothaman KR, Sirol M, Levy AP, Fuster V (2006) Neovascularization in human atherosclerosis. Circulation 113: 2245-2252.
-
(2006)
Circulation
, vol.113
, pp. 2245-2252
-
-
Moreno, P.R.1
Purushothaman, K.R.2
Sirol, M.3
Levy, A.P.4
Fuster, V.5
-
4
-
-
36049026182
-
Role of anti-angiogenesis agents in treating NSCLC: Focus on bevacizumab and VEGFR tyrosine kinase inhibitors
-
Cabebe E, Wakelee H (2007) Role of anti-angiogenesis agents in treating NSCLC: focus on bevacizumab and VEGFR tyrosine kinase inhibitors. Curr Treat Options Oncol 8: 15-27.
-
(2007)
Curr Treat Options Oncol
, vol.8
, pp. 15-27
-
-
Cabebe, E.1
Wakelee, H.2
-
5
-
-
34248653459
-
Plaque neovascularization and antiangiogenic therapy for atherosclerosis
-
Doyle B, Caplice N (2007) Plaque neovascularization and antiangiogenic therapy for atherosclerosis. J Am Coll Cardiol 49: 2073-2080.
-
(2007)
J Am Coll Cardiol
, vol.49
, pp. 2073-2080
-
-
Doyle, B.1
Caplice, N.2
-
6
-
-
49349103253
-
Intravitreous anti-VEGF for diabetic retinopathy: Hopes and fears for a new therapeutic strategy
-
Simo R, Hernandez C (2008) Intravitreous anti-VEGF for diabetic retinopathy: hopes and fears for a new therapeutic strategy. Diabetologia 51: 1574-1580.
-
(2008)
Diabetologia
, vol.51
, pp. 1574-1580
-
-
Simo, R.1
Hernandez, C.2
-
7
-
-
0033528660
-
Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovasculariza-tion and plaque growth in apolipoprotein E-deficient mice
-
Moulton KS, Heller E, Konerding MA, Flynn E, Palinski W, et al. (1999) Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovasculariza-tion and plaque growth in apolipoprotein E-deficient mice. Circulation 99: 1726-1732.
-
(1999)
Circulation
, vol.99
, pp. 1726-1732
-
-
Moulton, K.S.1
Heller, E.2
Konerding, M.A.3
Flynn, E.4
Palinski, W.5
-
8
-
-
0035187305
-
Tissue examination to monitor antiangiogenic therapy: A phase i clinical trial with endostatin
-
Mundhenke C, Thomas JP, Wilding G, Lee FT, Kelzc F, et al. (2001) Tissue examination to monitor antiangiogenic therapy: a phase I clinical trial with endostatin. Clin Cancer Res 7: 3366-3374.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3366-3374
-
-
Mundhenke, C.1
Thomas, J.P.2
Wilding, G.3
Lee, F.T.4
Kelzc, F.5
-
9
-
-
32344443105
-
China offers alternative gateway for experimental drugs
-
Jia H, Kling J (2006) China offers alternative gateway for experimental drugs. Nat Biotechnol 24: 117-118.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 117-118
-
-
Jia, H.1
Kling, J.2
-
10
-
-
84865136495
-
Recombinant human endostatin inhibits adjuvant arthritis by down-regulating VEGF expression and suppression of TNF-alpha, IL-1beta production
-
Hu W, Xia LJ, Chen FH, Wu FR, Tang J, et al. (2012) Recombinant human endostatin inhibits adjuvant arthritis by down-regulating VEGF expression and suppression of TNF-alpha, IL-1beta production. Inflamm Res 61: 827-835.
-
(2012)
Inflamm Res
, vol.61
, pp. 827-835
-
-
Hu, W.1
Xia, L.J.2
Chen, F.H.3
Wu, F.R.4
Tang, J.5
-
11
-
-
77955484157
-
Evaluation of recombinant endostatin in the treatment of atherosclerotic plaques and neovascularization in rabbits
-
Mao W, Kong J, Dai J, Huang ZQ, Wang DZ, et al. (2010) Evaluation of recombinant endostatin in the treatment of atherosclerotic plaques and neovascularization in rabbits. J Zhejiang Univ Sci B 11: 599-607.
-
(2010)
J Zhejiang Univ Sci B
, vol.11
, pp. 599-607
-
-
Mao, W.1
Kong, J.2
Dai, J.3
Huang, Z.Q.4
Wang, D.Z.5
-
12
-
-
34547106834
-
Endostar, a novel recombinant human endostatin, exerts antiangiogenic effect via blocking VEGF-induced tyrosine phosphorylation of KDR/Flk-1 of endothelial cells
-
Ling Y, Yang Y, Lu N, You QD, Wang S, et al. (2007) Endostar, a novel recombinant human endostatin, exerts antiangiogenic effect via blocking VEGF-induced tyrosine phosphorylation of KDR/Flk-1 of endothelial cells. Biochem Biophys Res Commun 361: 79-84.
-
(2007)
Biochem Biophys Res Commun
, vol.361
, pp. 79-84
-
-
Ling, Y.1
Yang, Y.2
Lu, N.3
You, Q.D.4
Wang, S.5
-
13
-
-
61449159933
-
Endostar induces apoptotic effects in HUVECs through activation of caspase-3 and decrease of Bcl-2
-
Ling Y, Lu N, Gao Y, Chen Y, Wang S, et al. (2009) Endostar induces apoptotic effects in HUVECs through activation of caspase-3 and decrease of Bcl-2. Anticancer Res 29: 411-417.
-
(2009)
Anticancer Res
, vol.29
, pp. 411-417
-
-
Ling, Y.1
Lu, N.2
Gao, Y.3
Chen, Y.4
Wang, S.5
-
14
-
-
84855201014
-
Endostar down-regulates HIF-1 and VEGF expression and enhances the radioresponse to human lung adenocarcinoma cancer cells
-
Zhang L, Ge W, Hu K, Zhang Y, Li C, et al. (2012) Endostar down-regulates HIF-1 and VEGF expression and enhances the radioresponse to human lung adenocarcinoma cancer cells. Mol Biol Rep 39: 89-95.
-
(2012)
Mol Biol Rep
, vol.39
, pp. 89-95
-
-
Zhang, L.1
Ge, W.2
Hu, K.3
Zhang, Y.4
Li, C.5
-
15
-
-
77958450885
-
The role of wnt signaling in physiological and pathological angiogenesis
-
Dejana E (2010) The role of wnt signaling in physiological and pathological angiogenesis. Circ Res 107: 943-952.
-
(2010)
Circ Res
, vol.107
, pp. 943-952
-
-
Dejana, E.1
-
17
-
-
77954210220
-
An updated overview on Wnt signaling pathways: A prelude for more
-
Rao TP, Kuhl M (2010) An updated overview on Wnt signaling pathways: a prelude for more. Circ Res 106: 1798-1806.
-
(2010)
Circ Res
, vol.106
, pp. 1798-1806
-
-
Rao, T.P.1
Kuhl, M.2
-
18
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H (2006) Wnt/beta-catenin signaling in development and disease. Cell 127: 469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
19
-
-
67650230896
-
Wnt/beta-catenin signaling: Components, mechanisms, and diseases
-
MacDonald BT, Tamai K, He X (2009) Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 17: 9-26.
-
(2009)
Dev Cell
, vol.17
, pp. 9-26
-
-
Macdonald, B.T.1
Tamai, K.2
He, X.3
-
20
-
-
24044500959
-
Wnt/beta-catenin signaling induces proliferation, survival and interleukin-8 in human endothelial cells
-
Masckauchan TN, Shawber CJ, Funahashi Y, Li CM, Kitajewski J (2005) Wnt/beta-catenin signaling induces proliferation, survival and interleukin-8 in human endothelial cells. Angiogenesis 8: 43-51.
-
(2005)
Angiogenesis
, vol.8
, pp. 43-51
-
-
Masckauchan, T.N.1
Shawber, C.J.2
Funahashi, Y.3
Li, C.M.4
Kitajewski, J.5
-
21
-
-
84858051662
-
Lymphoid enhancer-binding factor 1, a representative of vertebrate-specific Lef1/Tcf1 sub-family, is a Wnt-beta-catenin pathway target gene in human endothelial cells which regulates matrix metalloproteinase-2 expression and promotes endothelial cell invasion
-
Planutiene M, Planutis K, Holcombe RF (2011) Lymphoid enhancer-binding factor 1, a representative of vertebrate-specific Lef1/Tcf1 sub-family, is a Wnt-beta-catenin pathway target gene in human endothelial cells which regulates matrix metalloproteinase-2 expression and promotes endothelial cell invasion. Vasc Cell 3: 28.
-
(2011)
Vasc Cell
, vol.3
, pp. 28
-
-
Planutiene, M.1
Planutis, K.2
Holcombe, R.F.3
-
22
-
-
84861609140
-
In vitro and in vivo anti-angiogenic activities of Panduratin A
-
Lai SL, Cheah SC, Wong PF, Noor SM, Mustafa MR (2012) In vitro and in vivo anti-angiogenic activities of Panduratin A. PLoS One 7: e38103.
-
(2012)
PLoS One
, vol.7
, pp. e38103
-
-
Lai, S.L.1
Cheah, S.C.2
Wong, P.F.3
Noor, S.M.4
Mustafa, M.R.5
-
23
-
-
73849115202
-
Downregulation of E-cadherin is an essential event in activating beta-catenin/Tcf-dependent transcription and expression of its target genes in Pdcd4 knockdown cells
-
Wang Q, Sun ZX, Allgayer H, Yang HS (2010) Downregulation of E-cadherin is an essential event in activating beta-catenin/Tcf-dependent transcription and expression of its target genes in Pdcd4 knockdown cells. Oncogene 29: 128-138.
-
(2010)
Oncogene
, vol.29
, pp. 128-138
-
-
Wang, Q.1
Sun, Z.X.2
Allgayer, H.3
Yang, H.S.4
-
24
-
-
33746864818
-
Regulation of human nitric oxide synthase 2 expression by Wnt beta-catenin signaling
-
Du Q, Park KS, Guo Z, He P, Nagashima M, et al. (2006) Regulation of human nitric oxide synthase 2 expression by Wnt beta-catenin signaling. Cancer Res 66: 7024-7031.
-
(2006)
Cancer Res
, vol.66
, pp. 7024-7031
-
-
Du, Q.1
Park, K.S.2
Guo, Z.3
He, P.4
Nagashima, M.5
-
25
-
-
77958478957
-
Kruppel-like factor-4 transcriptionally regulates VE-cadherin expression and endothelial barrier function
-
Cowan CE, Kohler EE, Dugan TA, Mirza MK, Malik AB, et al. (2010) Kruppel-like factor-4 transcriptionally regulates VE-cadherin expression and endothelial barrier function. Circ Res 107: 959-966.
-
(2010)
Circ Res
, vol.107
, pp. 959-966
-
-
Cowan, C.E.1
Kohler, E.E.2
Dugan, T.A.3
Mirza, M.K.4
Malik, A.B.5
-
26
-
-
2342430184
-
Vasculogenesis and angiogenesis
-
Patan S (2004) Vasculogenesis and angiogenesis. Cancer Treat Res 117: 3-32.
-
(2004)
Cancer Treat Res
, vol.117
, pp. 3-32
-
-
Patan, S.1
-
27
-
-
34547221505
-
Understanding the biology of angiogenesis: Review of the most important molecular mechanisms
-
Otrock ZK, Mahfouz RA, Makarem JA, Shamseddine AI (2007) Understanding the biology of angiogenesis: review of the most important molecular mechanisms. Blood Cells Mol Dis 39: 212-220.
-
(2007)
Blood Cells Mol Dis
, vol.39
, pp. 212-220
-
-
Otrock, Z.K.1
Mahfouz, R.A.2
Makarem, J.A.3
Shamseddine, A.I.4
-
28
-
-
78651433124
-
Endostar, a modified recombinant human endostatin, exhibits synergistic effects with dexamethasone on angiogenesis and hepatoma growth
-
Li XQ, Shang BY, Wang DC, Zhang SH, Wu SY, et al. (2011) Endostar, a modified recombinant human endostatin, exhibits synergistic effects with dexamethasone on angiogenesis and hepatoma growth. Cancer Lett 301: 212-220.
-
(2011)
Cancer Lett
, vol.301
, pp. 212-220
-
-
Li, X.Q.1
Shang, B.Y.2
Wang, D.C.3
Zhang, S.H.4
Wu, S.Y.5
-
29
-
-
84883227223
-
Antitumor effects of Endostar on non-Hodgkin's lymphoma by regulating endothelial progenitor cells through protein kinase B-dependent pathway
-
Yu D, Wu H, Yang B, Yang K, Liu H, et al. (2013) Antitumor effects of Endostar on non-Hodgkin's lymphoma by regulating endothelial progenitor cells through protein kinase B-dependent pathway. Acta Biochim Biophys Sin (Shanghai) 45: 742-748.
-
(2013)
Acta Biochim Biophys Sin (Shanghai)
, vol.45
, pp. 742-748
-
-
Yu, D.1
Wu, H.2
Yang, B.3
Yang, K.4
Liu, H.5
-
30
-
-
84867375369
-
Synergistic antitumor effects of endostar in combination with oxaliplatin via inhibition of HIF and CXCR4 in the colorectal cell line SW1116
-
Jin F, Ji H, Jia C, Brockmeier U, Hermann DM, et al. (2012) Synergistic antitumor effects of endostar in combination with oxaliplatin via inhibition of HIF and CXCR4 in the colorectal cell line SW1116. PLoS One 7: e47161.
-
(2012)
PLoS One
, vol.7
, pp. e47161
-
-
Jin, F.1
Ji, H.2
Jia, C.3
Brockmeier, U.4
Hermann, D.M.5
-
31
-
-
33750973380
-
Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling
-
Goodwin AM, Sullivan KM, D'Amore PA (2006) Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling. Dev Dyn 235: 3110-3120.
-
(2006)
Dev Dyn
, vol.235
, pp. 3110-3120
-
-
Goodwin, A.M.1
Sullivan, K.M.2
D'Amore, P.A.3
-
32
-
-
77955977167
-
The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling
-
Corada M, Nyqvist D, Orsenigo F, Caprini A, Giampietro C, et al. (2010) The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling. Dev Cell 18: 938-949.
-
(2010)
Dev Cell
, vol.18
, pp. 938-949
-
-
Corada, M.1
Nyqvist, D.2
Orsenigo, F.3
Caprini, A.4
Giampietro, C.5
-
33
-
-
0141768242
-
The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility
-
Cattelino A, Liebner S, Gallini R, Zanetti A, Balconi G, et al. (2003) The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility. J Cell Biol 162: 1111-1122.
-
(2003)
J Cell Biol
, vol.162
, pp. 1111-1122
-
-
Cattelino, A.1
Liebner, S.2
Gallini, R.3
Zanetti, A.4
Balconi, G.5
-
34
-
-
77951050199
-
Blocking the Wnt pathway, a unifying mechanism for an angiogenic inhibitor in the serine proteinase inhibitor family
-
Zhang B, Abreu JG, Zhou K, Chen Y, Hu Y, et al. (2010) Blocking the Wnt pathway, a unifying mechanism for an angiogenic inhibitor in the serine proteinase inhibitor family. Proc Natl Acad Sci USA 107: 6900-6905.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 6900-6905
-
-
Zhang, B.1
Abreu, J.G.2
Zhou, K.3
Chen, Y.4
Hu, Y.5
-
35
-
-
0030949463
-
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
-
Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, et al. (1997) Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 275: 1787-1790.
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
Barker, N.4
Clevers, H.5
-
36
-
-
0027154638
-
Cyclin D1 is a nuclear protein required for cell cycle progression in G1
-
Baldin V, Lukas J, Marcote MJ, Pagano M, Draetta G (1993) Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Genes Dev 7: 812-821.
-
(1993)
Genes Dev
, vol.7
, pp. 812-821
-
-
Baldin, V.1
Lukas, J.2
Marcote, M.J.3
Pagano, M.4
Draetta, G.5
-
37
-
-
0033545845
-
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
-
Shtutman M, Zhurinsky J, Simcha I, Albanese C, D'Amico M, et al. (1999) The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. Proc Natl Acad Sci USA 96: 5522-5527.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5522-5527
-
-
Shtutman, M.1
Zhurinsky, J.2
Simcha, I.3
Albanese, C.4
D'Amico, M.5
-
38
-
-
80053010958
-
Comparison of the effects of recombinant human endostatin and docetaxel on human umbilical vein endothelial cells in different growth states
-
Xu WJ, Huang C, Wang J, Jiang RC, Wang LC, et al. (2011) Comparison of the effects of recombinant human endostatin and docetaxel on human umbilical vein endothelial cells in different growth states. Chin Med J (Engl) 124: 2883-2889.
-
(2011)
Chin Med J (Engl)
, vol.124
, pp. 2883-2889
-
-
Xu, W.J.1
Huang, C.2
Wang, J.3
Jiang, R.C.4
Wang, L.C.5
-
39
-
-
33646893508
-
Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling
-
Li Z, Wang C, Jiao X, Lu Y, Fu M, et al. (2006) Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling. Mol Cell Biol 26: 4240-4256.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 4240-4256
-
-
Li, Z.1
Wang, C.2
Jiao, X.3
Lu, Y.4
Fu, M.5
-
40
-
-
0037699954
-
The biology of VEGF and its receptors
-
Ferrara N, Gerber HP, LeCouter J (2003) The biology of VEGF and its receptors. Nat Med 9: 669-676.
-
(2003)
Nat Med
, vol.9
, pp. 669-676
-
-
Ferrara, N.1
Gerber, H.P.2
Lecouter, J.3
-
41
-
-
11144357806
-
Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor: Implications for ocular angiogenesis
-
Duh EJ, Yang HS, Haller JA, De Juan E, Humayun MS, et al. (2004) Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor: implications for ocular angiogenesis. Am J Ophthalmol 137: 668-674.
-
(2004)
Am J Ophthalmol
, vol.137
, pp. 668-674
-
-
Duh, E.J.1
Yang, H.S.2
Haller, J.A.3
De Juan, E.4
Humayun, M.S.5
-
42
-
-
0035882030
-
Regulation of vascular endothelial growth factor by the Wnt and K-ras pathways in colonic neoplasia
-
Zhang X, Gaspard JP, Chung DC (2001) Regulation of vascular endothelial growth factor by the Wnt and K-ras pathways in colonic neoplasia. Cancer Res 61: 6050-6054.
-
(2001)
Cancer Res
, vol.61
, pp. 6050-6054
-
-
Zhang, X.1
Gaspard, J.P.2
Chung, D.C.3
-
43
-
-
0038745735
-
Beta-Catenin regulates vascular endothelial growth factor expression in colon cancer
-
Easwaran V, Lee SH, Inge L, Guo L, Goldbeck C, et al. (2003) beta-Catenin regulates vascular endothelial growth factor expression in colon cancer. Cancer Res 63: 3145-3153.
-
(2003)
Cancer Res
, vol.63
, pp. 3145-3153
-
-
Easwaran, V.1
Lee, S.H.2
Inge, L.3
Guo, L.4
Goldbeck, C.5
-
44
-
-
14044278776
-
Glycogen-Synthase Kinase3beta/beta-catenin axis promotes angiogenesis through activation of vascular endothelial growth factor signaling in endothelial cells
-
Skurk C, Maatz H, Rocnik E, Bialik A, Force T, et al. (2005) Glycogen-Synthase Kinase3beta/beta-catenin axis promotes angiogenesis through activation of vascular endothelial growth factor signaling in endothelial cells. Circ Res 96: 308-318.
-
(2005)
Circ Res
, vol.96
, pp. 308-318
-
-
Skurk, C.1
Maatz, H.2
Rocnik, E.3
Bialik, A.4
Force, T.5
|