Fenitrothion action at the endocannabinoid system leading to spermatotoxicity in Wistar rats

Toxicology and Applied Pharmacology

Volumn 279, Issue 3, 2014, Pages 331-337

  Ito, Yuki ^a   Tomizawa, Motohiro ^a,b   Suzuki, Himiko ^a   Okamura, Ai ^c   Ohtani, Katsumi ^d   Nunome, Mari ^a   Noro, Yuki ^a   Wang, Dong ^c   Nakajima, Tamie ^c   Kamijima, Michihiro ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b TOKYO UNIVERSITY OF AGRICULTURE   (Japan)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d NATIONAL INSTITUTE OF OCCUPATIONAL SAFETY AND HEALTH   (Japan)

Author keywords

Anandamide; Endocannabinoid system; Fatty acid amide hydrolase; Fenitrothion; Organophosphate insecticide; Sperm toxicity

Indexed keywords

ADENOSINE TRIPHOSPHATE; DRUG METABOLITE; ENDOCANNABINOID; FATTY ACID AMIDASE; FENITROTHION; FLUORESCENT DYE; PROTEOME; ANANDAMIDE; ENDOCANNABINOID ANANDAMIDE HYDROLASE; HYDROLASE; PHOSPHONOFLUORIDATE FLUORESCENT PROBE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; IN VITRO STUDY; LONG TERM EXPOSURE; MALE; NONHUMAN; RAT; REPRODUCTIVE TOXICITY; SIGNAL TRANSDUCTION; SPERM; SPERMATOGENESIS; SPERMATOTOXICITY; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; TESTIS CELL; HORMONE DETERMINATION; MALE GENITAL TRACT PARAMETERS; SPERMATOZOON MORPHOLOGY; SPERMATOZOON TAIL; TESTIS;

ANANDAMIDE; ENDOCANNABINOID SYSTEM; FATTY ACID AMIDE HYDROLASE; FENITROTHION; ORGANOPHOSPHATE INSECTICIDE; SPERM TOXICITY;

ADENOSINE TRIPHOSPHATE; AMIDOHYDROLASES; ANIMALS; BEHAVIOR, ANIMAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENDOCANNABINOIDS; EPIDIDYMIS; FENITROTHION; GONADAL STEROID HORMONES; INSECTICIDES; MALE; MASS SPECTROMETRY; NEUROTOXICITY SYNDROMES; RATS; RATS, WISTAR; SPERM COUNT; SPERM MOTILITY; SPERMATOZOA; TESTIS;

EID: 84907192995     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.06.023     Document Type: Article

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