The in vitro therapeutic activity of betulinic acid nanocomposite on breast cancer cells (MCF-7) and normal fibroblast cell (3T3)

Journal of Materials Science

Volumn 49, Issue 23, 2014, Pages 8171-8182

  Hussein Al Ali, Samer Hasan ^a,b   Arulselvan, Palanisamy ^a   Fakurazi, Sharida ^a   Hussein, Mohd Zobir ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

^b ISRA UNIVERSITY   (Jordan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CONTROLLED DRUG DELIVERY; DISEASES; FIBROBLASTS; MAGNETIC NANOPARTICLES; TARGETED DRUG DELIVERY;

BREAST CANCER CELLS; DOSE-DEPENDENT MANNER; MAGNETIC NANOPARTI CLES (MNPS); MOUSE-FIBROBLASTS; POTENTIAL TECHNIQUES; PSEUDO-SECOND-ORDER KINETIC MODELS; RELEASE BEHAVIORS; THERAPEUTIC ACTIVITY;

NANOCOMPOSITES;

EID: 84907168776     PISSN: 00222461     EISSN: 15734803     Source Type: Journal    
DOI: 10.1007/s10853-014-8526-3     Document Type: Article

References (35)

1. Pisha E et al (1995) Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis. Nat Med 1(10):1046-1051
2. Zuco V et al (2002) Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cells. Cancer Lett 175(1):17-25
3. Wick W et al (1999) Betulinic acid-induced apoptosis in glioma cells: a sequential requirement for new protein synthesis, formation of reactive oxygen species, and caspase processing. J Pharmacol Exp Ther 289(3):1306-1312
4. Ji Z-N et al (2002) 23-Hydroxybetulinic acid-mediated apoptosis is accompanied by decreases in bcl-2 expression and telomerase activity in HL-60 cells. Life Sci 72(1):1-9
5. Thurnher D et al (2003) Betulinic acid: a new cytotoxic compound against malignant head and neck cancer cells. Head Neck 25(9):732-740
6. Kim JY et al (2001) Development of C-20 modified betulinic acid derivatives as antitumor agents. Bioorg Med Chem Lett 11(17):2405-2408
7. Chatterjee P et al (2000) Biotransformation of the antimelanoma agent betulinic acid by Bacillus megaterium ATCC 13368. Appl Environ Microbiol 66(9):3850-3855
8. Hussein-Al-Ali SH et al (2014) Arginine-chitosan- and arginine-polyethylene glycol-conjugated superparamagnetic nanoparticles: preparation, cytotoxicity, and controlled-release. J Biomater Appl [Epub ahead of print]
9. Dilnawaz F et al (2010) Dual drug loaded superparamagnetic iron oxide nanoparticles for targeted cancer therapy. Biomaterials 31(13):3694-3706
10. Qu J-B et al (2013) PEG-chitosan-coated iron oxide nanoparticles with high saturated magnetization as carriers of 10-hydroxycamptothecin: preparation, characterization and cytotoxicity studies. Colloid Surf B 102(1):37-44
11. Wang YX et al (2001) Superparamagnetic iron oxide contrast agents: physicochemical characteristics and applications in MR imaging. Eur Radiol 11(11):2319-2331
12. Mahmoudi M et al (2009) Cell toxicity of superparamagnetic iron oxide nanoparticles. J Colloid Interface Sci 336(2):510-518
13. Xu ZP et al (2006) Inorganic nanoparticles as carriers for efficient cellular delivery. Chem Eng Sci 61(3):1027-1040
14. Chen Y-C et al (2012) In vitro evaluation of the L-peptide modified magnetic lipid nanoparticles as targeted magnetic resonance imaging contrast agent for the nasopharyngeal cancer. J Biomater Appl 28(4):580-594
15. Inbaraj BS et al (2011) The synthesis and characterization of poly (gamma-glutamic acid)-coated magnetite nanoparticles and their effects on antibacterial activity and cytotoxicity. Nanotechnology 22(7):075101
16. 3-NaOH aqueous system. J Biomater Appl 25(7):643-661
17. Zheng SW et al (2013) RGD-conjugated iron oxide magnetic nanoparticles for magnetic resonance imaging contrast enhancement and hyperthermia. J Biomater Appl 28(7):1051-1059
18. Panos I et al (2008) New drug delivery systems based on chitosan. Curr Drug Discov Technol 5(4):333-341
19. Unsoy G et al (2012) Synthesis optimization and characterization of chitosan-coated iron oxide nanoparticles produced for biomedical applications. J Nanopart Res 14(11):1-13
20. Predoi D (2007) A study on iron oxide nanoparticles coated with dextrin obtained by coprecipitation. Dig J Nanomater Biostruct 2:169-173
21. Inbaraj BS et al (2012) Synthesis, characterization and antibacterial activity of superparamagnetic nanoparticles modified with glycol chitosan. Sci Technol Adv Mater 13(1):37-44
22. 4nanostructures and their cytotoxicity. Mater Res Express 1(1):015015
23. Kayal S, Ramanujan RV (2010) Anti-cancer drug loaded iron-gold core-shell nanoparticles (FeAu) for magnetic drug targeting. J Nanosci Nanotechnol 10(9):5527-5539
24. Mandal M et al (2005) Magnetite nanoparticles with tunable gold or silver shell. J Colloid Interface Sci 286(1):187-194
25. Li P et al (2004) Synthesis and characterization of a high oil-absorbing magnetic composite material. J Appl Polym Sci 93(2):894-900
26. 4nanoparticles. J Biomed Mater Res A 80(2):333-341
27. Kumar R et al (2010) Surface modification of superparamagnetic iron nanoparticles with calcium salt of poly (gamma-glutamic acid) as coating material. Mater Res Bull 45(11):1603-1607
28. Marchessault RH et al (2006) Polysaccharides for drug delivery and pharmaceutical applications. American Chemical Society, Washington, DC
29. Soica CM et al (2012) Physico-chemical comparison of betulinic acid, betulin and birch bark extract and in vitro investigation of their cytotoxic effects towards skin epidermoid carcinoma (A431), breast carcinoma (MCF7) and cervix adenocarcinoma (HeLa) cell lines. Nat Prod Res 26(10):968-974
30. Shan Z et al (2007) Preparation and characterization of carboxyl-group functionalized superparamagnetic nanoparticles and the potential for bio-applications. J Braz Chem Soc 18(7):1329-1335
31. Gupta R, Bajpai AK (2012) Superparamagnetic nanocomposites of poly (vinyl alcohol-graft-acrylonitrile) as carrier for magnetically assisted release of ciprofloxacin. Macromol Symp 315(1):73-83
32. Hussein-Al-Ali SH et al (2014) Synthesis, characterization and antimicrobial activity of a novel ampicillin-conjugated magnetic nano-antibiotic. Int J Nanomed 9
33. Dong L et al (2010) Synthesis and release behavior of composites of camptothecin and layered double hydroxide. J Solid State Chem 183(8):1811-1816
34. Ho YS, Ofomaja AE (2006) Pseudo-second-order model for lead ion sorption from aqueous solutions onto palm kernel fiber. J Hazard Mater 129(1-3):137-142
35. Sakore S, Chakraborty B (2013) Formulation and evaluation of enalapril maleate sustained release matrix tablets. Int J Pharm 4(1):21-26