Inhibitors of the 5-lipoxygenase pathway activate pannexin1 channels in macrophages via the thromboxane receptor

American Journal of Physiology - Cell Physiology

Volumn 307, Issue 6, 2014, Pages C571-C579

  da Silva Souza, Hercules A ^a,b,c   de Lira, Maria Nathália ^a   Patel, Naman K ^c   Spray, David C ^c   Persechini, Pedro Muanis ^a,b   Scemes, Eliana ^c  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b Inst Nac de Cie e Tecnologia Para Pesquisa Translacional em Saude e Ambiente Na Regiao Amazonica   (Brazil)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

ATP release; Dye uptake; Macrophages; Pannexin; Prostanoids

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ADENOSINE TRIPHOSPHATE; ADENYLATE CYCLASE; ANNEXIN; CYCLIC AMP; NORDIHYDROGUAIARETIC ACID; PANNEXIN 1; PROSTAGLANDIN H2; THROMBOXANE A2; THROMBOXANE RECEPTOR; UNCLASSIFIED DRUG; CYCLIC AMP DEPENDENT PROTEIN KINASE; GAP JUNCTION PROTEIN; LIPOXYGENASE INHIBITOR; NERVE PROTEIN; PANNEXIN; PANX1 PROTEIN, MOUSE;

ADAPTIVE IMMUNITY; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; INNATE IMMUNITY; INTRACELLULAR SIGNALING; MACROPHAGE MIGRATION; MALE; MONOCYTE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; ATP RELEASE; C57BL MOUSE; CELL LINE; DRUG EFFECT; DYE UPTAKE; GENETICS; KNOCKOUT MOUSE; MACROPHAGE; MEMBRANE POTENTIAL; METABOLISM; PROSTANOIDS;

ATP RELEASE; DYE UPTAKE; MACROPHAGES; PANNEXIN; PROSTANOIDS;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL LINE; CONNEXINS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; LIPOXYGENASE INHIBITORS; MACROPHAGES, PERITONEAL; MALE; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; RECEPTORS, THROMBOXANE; SIGNAL TRANSDUCTION;

EID: 84907158809     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00087.2014     Document Type: Article

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