Pyrimidinoceptor-mediated activation of phospholipase C and phospholipase A2 in RAW 264.7 macrophages

British Journal of Pharmacology

Volumn 119, Issue 2, 1996, Pages 261-268

  Lin, W W ^a   Lee, Y T ^b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Adenosine 5' triphosphate (ATP); Phospholipase A2; Phospholipase C; Pyrimidinoceptor; RAW 264.7 macrophages; Uridine 5' triphosphate (UTP)

Indexed keywords

ADENOSINE TRIPHOSPHATE; ARACHIDONIC ACID; CALCIUM ION; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL PHOSPHATE; PERTUSSIS TOXIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOLIPASE A2; PHOSPHOLIPASE C; PURINE P2 RECEPTOR; SURAMIN; URIDINE DIPHOSPHATE; URIDINE TRIPHOSPHATE;

ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; EXTRACELLULAR CALCIUM; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0029813906     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15980.x     Document Type: Article

References (42)

1. BARNARD, E.A., BURNSTOCK, G. & WEBB, T.E. (1994). G Protein-coupled receptors for ATP and other nucleotides: a new receptor family. Trends Pharmacol. Sci., 15, 67-70.
2. 62B glioma cells. J. Biol. Chem., 264, 20147-20153.
3. 2. Glia, 7, 219-224.
4. 2 in pulmonary endothelium. Eur. J. Biochem., 206, 965-972.
5. 2 with membrane in the macrophage cell line RAW 264.7. J. Biol. Chem., 265, 5409-5413.
6. 2+-dependent translocation domain with homology to PKC and GAP. Cell, 65, 1043-1051.
7. 2 via G-protein(s). Biochem. J., 263, 715-723.
8. CONNOLLY, G.P. & HARRISON, P.J. (1994). Reactive blue 2 discriminates between responses mediated by UTP and those evoked by ATP or α,β-methylene-ATP on rat sympathetic ganglia. Eur. J. Pharmacol., 259, 95-99.
9. COWEN, D.S., LAZARUS, H.M., SHURIN, S.B., STOLL, S.E. & DUBYAK, G.R. (1989). Extracellular adenosine triphosphate activates calcium mobilization in human phagocytic leukocytes and neutrophil/monocyte progenitor cells. J. Clin. Invest., 83, 1651-1660.
10. CRACK, B.E., POLLARD, C.E., BEUKERS, M.W., ROBERTS, S.M., HUNT, S.F., INGALL, A.H., MCKECHNIE, K.C.W., IJZERMAN, A.P. & LEFF, P. (1995). Pharmacological and biochemical analysis of FPL 67156, a novel, selective inhibitor of ecto-ATPase. Br. J. Pharmacol., 114, 475-481.
11. 2-purinergic receptors: evidence for mediation by both pertussis toxin-sensitive and -insensitive mechanisms. J. Biol. Chem., 263, 18107-18117.
12. 2z purinergic receptors in BAC1.2F5 macrophages. J Biol. Chem., 267, 23664-23673.
13. ELSBACH, P. & WEISS, J. (1988). Phagocytosis of bacteria and phospholipid degradation. Biochim. Biophys. Acta, 947, 29-52.
14. 2 purinoceptor in transformed mouse fibroblasts. J. Biol. Chem., 265, 7424-7431.
15. FREDHOLM, B.B., ABBRACCHIO, M.P., BURNSTOCK, G., DALY, J.W., HARDEN, K., JACOBSON, K.A., LEFF, P. & WILLIAMS, M. (1994). Nomenclature and classification of purinoceptors. Pharmacol. Rev., 46, 143-156.
16. GERRITSEN, M.E. & MANNIX, R.J. (1990). G-Proteins and phospholipase activation in endothelial cells. Adv. Exp. Med. Biol., 275, 115-124.
17. GOETZ, U., DAPRADA, M. & PLETSCHER, A. (1971). Adenine, guanine, and uridine-5′-phosphonucleotides in blood platelets and storage organelles of various species. J. Pharmacol. Exp. Ther., 178, 210-215.
18. 2+ fluxes in J774 macrophages by two distinct mechanisms. J. Biol. Chem., 263, 10337-10343.
19. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem., 260, 3440-3450.
20. 2-Purinergic receptors: subtype-associated signaling responses and structure. Ann. Rev. Pharmacol. Toxicol., 35, 541-579.
21. HAUSSINGER, D., STEHLE, T. & GEROK, W. (1987). Actions of extracellular UTP and ATP in perfused rat liver. Eur. J. Pharmacol., 167, 65-71.
22. 2 activity in bovine rod outer segments by the β,γ subunits of transducin and its inhibition by the α subunit. Proc. Natl. Acad. Sci. U.S.A., 84, 3623-3627.
23. 2. Nature, 337, 557-560.
24. LAZAROWSKI, E.R., BOUCHER, R.C. & HARDEN, T.K. (1994). Calcium-dependent release of arachidonic acid in response to purinergic receptor activation in airway epithelium. Am. J. Physiol., 266, C406-415.
25. LAZAROWSKI, E.R. & HARDEN, T.K. (1994). Identification of a uridine nucleotide-selective G-protein-linked receptor that activates phospholipase C. J. Biol. Chem., 269, 11830-11836.
26. 2 is phosphorylated and activated by MAP kinase. Cell, 72, 269-278.
27. 6 glioma cells for mediating phosphoinositide turnover. J. Neurochem., 62, 536-542.
28. 6 glioma cells. J. Pharmacol. Exp. Ther., 269, 926-931.
29. LUSITG, K.D., SHIAU, A.K., BRAKE, A.J. & JULIUS, D. (1993). Expression cloning of an ATP receptor from mouse neuroblastoma cells. Proc. Natl. Acad. Sci. U.S.A., 90, 5113-5117.
30. 2(s): comparison of arachidonyl-selective and -nonselective enzymes. FASEB J., 7, 339-348.
31. O'CONNOR, S.E., DAINTY, I.A. & LEFF, P. (1991). Further subclassification of ATP receptors based on agonist studies. Trends Pharmacol. Sci., 12, 137-141.
32. 2 from bovine endothelial cells. J. Biol Chem., 268, 11697-11702.
33. 2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy. Proc. Natl. Acad. Sci. U.S.A., 91, 3275-3279.
34. PFEILSCHIFTER, J., THURING, B. & FESTA, F. (1989). Extracellular ATP stimulates poly- (inositol phospholipid) hydrolysis and eicosanoid synthesis in mouse peritoneal macrophages in culture. Eur. J. Biochem., 186, 509-513.
35. RASCHKE, W.C., BAIRD, S., NAKOINZ, I. & RALPH, P. (1978). Functional macrophage cell lines transformed by Ableson leukemia virus. Cell, 15, 261-267.
36. 2-purinergic/pyrimidinergic receptor. J. Neurochem., 64, 61-68.
37. SEIFERT, R. & SCHULTZ, G. (1989). Involvement of pyrimidinoceptors in the regulation of cell functions by urine and by uracil nucleotides. Trends Pharmacol. Sci., 10, 365-369.
38. 2-purinoceptor, in rabbit ear artery. Naunyn-Schmiedeberg's Arch. Pharmacol., 336, 556-560.
39. 2X-receptor, in rabbit basilar artery: a receptor for pyrimidine nucleotides and a receptor for purine nucleotides. Naunyn-Schmiedebergs Arch. Pharmacol., 341, 538-546.
40. 27-purinoceptor of human lymphocytes: actions of nucleotide agonists and irreversible inhibition by oxidized ATP Br. J. Pharmacol., 112, 946-950.
41. 2+ and mitogen-activated protein kinase regulation. J. Biol. Chem., 269, 1889-1895.
42. 2+ in HL60 granulocytes. J. Biol. Chem., 267, 25966-25975.