Cytochrome P450 monooxygenase CYP53 family in fungi: Comparative structural and evolutionary analysis and its role as a common alternative anti-fungal drug target

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Jawallapersand, Poojah ^a   Mashele, Samson Sitheni ^a   Kovačič, Lidija ^b,c   Stojan, Jure ^d   Komel, Radovan ^e   Pakala, Suresh Babu ^f   Kraševec, Nada ^e   Syed, Khajamohiddin ^a  

^a CENTRAL UNIVERSITY OF TECHNOLOGY   (South Africa)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

^c JO EF STEFAN INSTITUTE   (Slovenia)

^d UNIVERSITY OF LJUBLJANA   (Slovenia)

^e NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

^f SRI KRISHNADEVARAYA UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; ANTIFUNGAL AGENT; CYTOCHROME P450; FUNGAL PROTEIN; PROTEIN CYP53; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; ASCOMYCETES; BASIDIOMYCETES; DEGRADATION; DETOXIFICATION; DRUG TARGETING; FUNGAL GENOME; GENE DUPLICATION; GENE MAPPING; GENE STRUCTURE; GENETIC CONSERVATION; GENOME ANALYSIS; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; NONHUMAN; PHYLOGENY; PHYLUM; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN STRUCTURE; SPECIES DIFFERENCE; SPECIES DIVERSITY; WOOD; ENZYMOLOGY; FUNGUS; GENETICS;

FUNGI;

ASCOMYCOTA; BASIDIOMYCOTA; CYTOCHROME P-450 ENZYME SYSTEM; FUNGI; GENOME, FUNGAL; PHYLOGENY;

EID: 84907157750     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0107209     Document Type: Article

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