Radix Angelicae Sinensis and Radix Hedysari enhance radiosensitivity of 12C6+ radiation in human liver cancer cells by modulating apoptosis protein

Saudi Medical Journal

Volumn 35, Issue 9, 2014, Pages 945-952

  Kou, Wei ^a   Li, Ying Dong ^a,b   Liu, Kai ^b   Sun, Shao Bo ^b   Dong, Yu Mei ^b   Wu, Zhen Hua ^c  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b LANZHOU UNIVERSITY   (China)

^c INSTITUTE OF MODERN PHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANGELICA ROOT EXTRACT; APOPTOSIS REGULATORY PROTEIN; CARBON; CASPASE 9; PLANT EXTRACT; RADIOSENSITIZING AGENT; RADIX HEDYSARI EXTRACT; SURVIVIN; UNCLASSIFIED DRUG; ANGELICAE SINENSIS EXTRACT; HERBACEOUS AGENT; HUANG QI;

APOPTOSIS; ARTICLE; CELL CYCLE PROGRESSION; CELL GROWTH; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; HEAVY ION RADIATION; HUMAN; HUMAN CELL; LINEAR ENERGY TRANSFER; LIVER CANCER; PROTEIN EXPRESSION; RADIATION EXPOSURE; RADIOSENSITIVITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; LIVER NEOPLASMS; PATHOLOGY; RADIATION DOSE; RADIATION RESPONSE; TUMOR CELL LINE;

APOPTOSIS; CELL LINE, TUMOR; DRUGS, CHINESE HERBAL; HUMANS; LIVER NEOPLASMS; RADIATION TOLERANCE;

EID: 84907154575     PISSN: 03795284     EISSN: 16583175     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Nakano T, Suzuki Y, Ohno T, Kato S, Suzuki M, Morita S, et al. Carbon beam therapy overcomes the radiation resistance of uterine cervical cancer originating from hypoxia. Clin Cancer Res 2006; 12: 2185-2190.
2. 6+ irradiation on cell cycle, apoptosis, and expression of caspase-3 in the human lung cancer cell line H1299. Cancer Biother Radiopharm 2012; 27: 113-118.
3. Lin SH, George TJ, Ben-Josef E, Bradley J, Choe KS, Edelman MJ, et al. Opportunities and challenges in the era of molecularly targeted agents and radiation therapy. J Natl Cancer Inst 2013; 105: 686-693.
4. Fan Q, Li YD, Shu C, Jing M, Lin XY. Purification of Danggui Buxue decoction by ultrafiltration membrane technology. Chinese Traditional Patent Medicine 2010; 32: 1438-1440.
5. Ma JH, Li X, Tan CJ, He FY, Li N, Yang M. Preliminary study on quality control model of Danggui Buxue Decoction based on physicochemical characterization. Chinese Traditional and Herbal Drugs 2012; 43: 901-905.
6. Zhang SY, Feng P, Yang M. Effect of Danggui Buxue Decoction on Proliferation and its Molecular Mechanism in Tumor Vascular Endothelial Cells. Chinese Journal of Experimental Traditional Medical Formulae 2013; 19: 108-112.
7. Morse KF, Wolfe CM. Radiobiology. Radiation Therapy for Skin Cancer 2013; 9-16.
8. Suboj P, Babykutty S, Srinivas P, Gopala S. Aloe emodin induces G2/M cell cycle arrest and apoptosis via activation of caspase-6 in human colon cancer cells. Pharmacology 2012; 89: 91-98.
9. Lim MJ, Ahn JY, Han Y, Yu CH, Kim MH, Lee SL, et al. Acriflavine enhances radiosensitivity of colon cancer cells through endoplasmic reticulum stress-mediated apoptosis. Int J Biochem Cell Biol 2012; 8: 1214-1222.
10. Pop C, Salvesen GS. Human caspases: activation, specificity, and regulation. J Biol Chem 2009; 284: 21777-21781.
11. Björn K, Azadeh N, Sten O, Boris Z, Vladimir G. Citrate kills tumor cells through activation of apical caspases. Cellular and Molecular Life Sciences 2012; 69: 4229-4237.
12. Würstle ML, Laussmann MA, Rehm M. The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome. Exp Cell Res 2012; 318: 1213-1220.
13. Altieri DC. Survivin and IAP proteins in cell-death mechanisms. Biochem J 2010; 430: 199-205.
14. Li S, Tian D, Fei P, Gao Y, Chen Z, Wang Q, et al. A cyclooxygase-2 inhibitor NS-398-enhanced apoptosis of esophageal carcinoma cell EC9706 by adjusting expression of survivin and caspase-3. Cancer Invest 2011; 29: 102-106.
15. Jiang XD, Qiao Y, Dai P, Chen Q, Wu J, Song DA, Li SQ. Enhancement of recombinant human endostatin on the radiosensitivity of human pulmonary adenocarcinoma A549 cells and its mechanism. J Biomed Biotechnol 2012; 2012: 301931.
16. Hamada N, Hara T, Funayama T, Sakashita T, Kobayashi Y. Energetic heavy ions accelerate differentiation in the descendants of irradiated normal human diploid fibroblasts. Mutat Res 2008; 637:190-196.
17. Hamada N, Ni M, Funayama T, Sakashita T, Kobayashi Y. Temporally distinct response of irradiated normal human fibroblasts and their bystander cells to energetic heavy ions. Mutat Res 2008; 639: 35-44.
18. Wang R, Li B, Wang X, Lin F, Gao P, Cheng SY, et al. Inhibiting XIAP expression by RNAi to inhibit proliferation and enhance radiosensitivity in laryngeal cancer cell line. Auris Nasus Larynx 2009; 36: 332-339.
19. Fan YJ, Huang NS, Xia L. Genistein synergizes with RNA interference inhibiting surviving for inducing DU-145 of prostate cancer cells to apoptosis. Cancer Letters 2009; 284: 189-197.
20. Koob AO, Bruns L, Prassler C, Masliah E, Klopstock T, Bender A. Protein analysis through Western blot of cells excised individually from human brain and muscle tissue. Anal Biochem 2012; 425: 120-124.
21. Cabrera R, Nelson DR. Review article: the management of hepatocellular carcinoma. Aliment Pharmacol Ther 2010; 31: 461-476.
22. Siegel R, Ward E, Brawley O, Jemal A. Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 2011; 61: 212-236.
23. Wörns MA, Weinmann A, Pfingst K, Carla SS, Messow CM, Henning SB, et al. Safety and efficacy of sorafenib in patients with advanced hepatocellular carcinoma in consideration of concomitant stage of liver cirrhosis. J Clin Gastroenterol 2009; 43: 489-495.
24. Fan Q, Li YD, Zhao WJ, Purification of polysaccharide from Angelica sinensis by ultrafiltration membrane technology. Chinese Journal of Information on TCM 2009;16: 54-55.
25. Li YZ, Huang J, Guo HC, Ren B. Chemical constituents from Hedysarum polybotrys and their antitumor activities. Chinese Traditional and Herbal Drugs 2009; 40: 1195-1198.
26. Song SD, Wang JW, Wang YP. Experimental study on the effect of angelica polysaccharide on inhibition of proliferation and induced differentiation towards erythroid cell of human erythroleukemia cell line (K562). Journal of Chongqing Medical University 2008; 33: 1-5.
27. Song SD, Wang JW, Wang LT, Chen SY, Yang AG. Cancer gene therapy targeting cellular apoptosis machinery. Cancer Treat Rev 2012; 38: 868-876.
28. Meyn RE, Munshi A, Haymach JV, Milas L, Ang KK. Receptor signaling as a regulatory mechanism of DNA repair. Radiother Oncol 2009; 92: 316-322.
29. Caiozzo VJ, Giedzinski E, Baker M, Suarez T, Izadi A, Lan M. The radiosensitivity of satellite cells: cell cycle regulation, apoptosis and oxidative Stress. Radiat Res 2010; 174: 582-589.
30. Zhao LQ, Lu XB, Cao Y. Micro RNA and signal transduction pathways in tumor radiation response. Cell Signal 2013; 25: 1625-1634.
31. Luo J, Chen X, Chen G, Zhou X, Lu X, Ling Y, et al. Dihydroartemisinin induces radiosensitivity in cervical cancer cells by modulating cell cycle progression. Saudi Med J 2013; 34: 254-260.
32. Haimovitz-Friedman A, Yang TJ, Thin TH, Verheij M. Imaging radiotherapy-induced apoptosis. Radiat Res 2012; 177: 467-482.
33. Esteve PO, Chin HG, Pradhan S. Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells. J Biol Chem 2007; 282: 2615-2625.
34. Ryan BM, O'Donovan N, Duffy MJ. Survivin: A new target for anti-cancer therapy. Cancer Treat Rev 2009; 35: 553-562.
35. Kanwar RK, Cheung CH, Chang JY, Kanwar JR. Recent advances in anti-survivin treatments for cancer. Curr Med Chem 2010; 17: 1509-1515.
36. Wang YX, Zhao L, Wang XY, Liu CM, Yu SG. Role of Caspase 8, Caspase 9 and Bcl-2 polymorphisms in papillary thyroid carcinoma risk in Han Chinese population. Med Oncol 2012; 28: 2445-2451.
37. Theodoropoulos GE, Michalopoulos NV, Panoussopoulos SG, Taka S, Gazouli M. Effects of caspase-9 and survivin gene polymorphisms in pancreatic cancer risk and tumor characteristics. Pancreas 2010; 39: 976-980.
38. Mori E, Takahashi A, Yamakawa N, Kirita T, Ohnishi T. High LET heavy ion radiation induces p53-independent apoptosis. J Radiat Res 2008; 50: 37-42.