Citrate kills tumor cells through activation of apical caspases

Cellular and Molecular Life Sciences

Volumn 69, Issue 24, 2012, Pages 4229-4237

  Kruspig, Björn ^a   Nilchian, Azadeh ^a   Orrenius, Sten ^a   Zhivotovsky, Boris ^a,b   Gogvadze, Vladimir ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

Apoptosis; Caspases; Citrate; Glycolysis

Indexed keywords

CASPASE 2; CASPASE 8; CITRIC ACID; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL METABOLISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIMERIZATION; DRUG MECHANISM; ENERGY METABOLISM; ENZYME ACTIVATION; PROTEIN CLEAVAGE; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION;

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 2; CASPASE 8; CELL LINE, TUMOR; CITRIC ACID; HUMANS; JURKAT CELLS;

EID: 84870655116     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-012-1166-3     Document Type: Article

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