메뉴 건너뛰기




Volumn 82, Issue 10, 2014, Pages 4127-4134

Porphyromonas gingivalis exacerbates ligature-induced, RANKLdependent alveolar bone resorption via differential regulation of Toll-like receptor 2 (TLR2) and TLR4

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE ANTIBODY; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; TLR2 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE; TNFSF11 PROTEIN, MOUSE;

EID: 84907104245     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.02084-14     Document Type: Article
Times cited : (86)

References (46)
  • 1
    • 0031992463 scopus 로고    scopus 로고
    • Periodontal diseases in the United States population
    • Oliver RC, Brown LJ, Loe H. 1998. Periodontal diseases in the United States population. J. Periodontol. 69:269-278. http://dx.doi.org/10.1902 /jop.1998.69.2.269.
    • (1998) J. Periodontol. , vol.69 , pp. 269-278
    • Oliver, R.C.1    Brown, L.J.2    Loe, H.3
  • 2
    • 0036397481 scopus 로고    scopus 로고
    • Microbial/host interactions: mechanisms involved in host responses to microbial antigens
    • Michalek SM, Katz J, Childers NK, Martin M, Balkovetz DF. 2002. Microbial/host interactions: mechanisms involved in host responses to microbial antigens. Immunol. Res. 26:223-234. http://dx.doi.org/10.1385 /IR:26:1-3:223.
    • (2002) Immunol. Res. , vol.26 , pp. 223-234
    • Michalek, S.M.1    Katz, J.2    Childers, N.K.3    Martin, M.4    Balkovetz, D.F.5
  • 3
    • 28644452244 scopus 로고    scopus 로고
    • Immune response: the key to bone resorption in periodontal disease
    • Taubman MA, Valverde P, Han X, Kawai T. 2005. Immune response: the key to bone resorption in periodontal disease. J. Periodontol. 76:2033-2041. http://dx.doi.org/10.1902/jop.2005.76.11-S.2033.
    • (2005) J. Periodontol. , vol.76 , pp. 2033-2041
    • Taubman, M.A.1    Valverde, P.2    Han, X.3    Kawai, T.4
  • 4
    • 84893587232 scopus 로고    scopus 로고
    • Breaking bad: manipulation of the host response by Porphyromonas gingivalis
    • Hajishengallis G, Lamont RJ. 2014. Breaking bad: manipulation of the host response by Porphyromonas gingivalis. Eur. J. Immunol. 44:328-338. http://dx.doi.org/10.1002/eji.201344202.
    • (2014) Eur. J. Immunol. , vol.44 , pp. 328-338
    • Hajishengallis, G.1    Lamont, R.J.2
  • 5
    • 84891372427 scopus 로고    scopus 로고
    • Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response
    • Hajishengallis G. 2014. Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response. Trends Immunol. 35:3-11. http://dx.doi.org/10.1016/j.it.2013.09.001.
    • (2014) Trends Immunol , vol.35 , pp. 3-11
    • Hajishengallis, G.1
  • 6
    • 33748499155 scopus 로고    scopus 로고
    • Pattern recognition receptors: an update
    • Goutagny N, Fitzgerald KA. 2006. Pattern recognition receptors: an update. Expert Rev. Clin. Immunol. 2:569-583. http://dx.doi.org/10.1586 /1744666X.2.4.569.
    • (2006) Expert Rev. Clin. Immunol. , vol.2 , pp. 569-583
    • Goutagny, N.1    Fitzgerald, K.A.2
  • 7
    • 61849170035 scopus 로고    scopus 로고
    • TLRs and innate immunity
    • Beutler BA. 2009. TLRs and innate immunity. Blood 113:1399-1407. http://dx.doi.org/10.1182/blood-2008-07-019307.
    • (2009) Blood , vol.113 , pp. 1399-1407
    • Beutler, B.A.1
  • 8
    • 79956300649 scopus 로고    scopus 로고
    • Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
    • Kawai T, Akira S. 2011. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34:637-650. http: //dx.doi.org/10.1016/j.immuni.2011.05.006.
    • (2011) Immunity , vol.34 , pp. 637-650
    • Kawai, T.1    Akira, S.2
  • 9
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki A, Medzhitov R. 2004. Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5:987-995. http://dx.doi.org/10.1038 /ni1112.
    • (2004) Nat. Immunol. , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 10
    • 0037460116 scopus 로고    scopus 로고
    • Recognition of pathogen-associated molecular patterns by TLR family
    • Akira S, Hemmi H. 2003. Recognition of pathogen-associated molecular patterns by TLR family. Immunol. Lett. 85:85-95. http://dx.doi.org/10 .1016/S0165-2478(02)00228-6.
    • (2003) Immunol. Lett. , vol.85 , pp. 85-95
    • Akira, S.1    Hemmi, H.2
  • 12
    • 0033952703 scopus 로고    scopus 로고
    • Tlr4: central component of the sole mammalian LPS sensor
    • Beutler B. 2000. Tlr4: central component of the sole mammalian LPS sensor. Curr. Opin. Immunol. 12:20-26. http://dx.doi.org/10.1016/S0952 -7915(99)00046-1.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 20-26
    • Beutler, B.1
  • 14
    • 0033145150 scopus 로고    scopus 로고
    • Ecological considerations in the treatment of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis periodontal infections
    • Socransky SS, Haffajee AD, Ximenez-Fyvie LA, Feres M, Mager D. 1999. Ecological considerations in the treatment of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis periodontal infections. Periodontol. 2000 20:341-362. http://dx.doi.org/10.1111/j.1600-0757 .1999.tb00165.x.
    • (2000) Periodontol , vol.20 , pp. 341-362
    • Socransky, S.S.1    Haffajee, A.D.2    Ximenez-Fyvie, L.A.3    Feres, M.4    Mager, D.5
  • 15
    • 84865276077 scopus 로고    scopus 로고
    • Porphyromonas gingivalis as a potential community activist for disease
    • Darveau RP, Hajishengallis G, Curtis MA. 2012. Porphyromonas gingivalis as a potential community activist for disease. J. Dent. Res. 91:816-820. http://dx.doi.org/10.1177/0022034512453589.
    • (2012) J. Dent. Res. , vol.91 , pp. 816-820
    • Darveau, R.P.1    Hajishengallis, G.2    Curtis, M.A.3
  • 16
    • 84869006781 scopus 로고    scopus 로고
    • Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology
    • Hajishengallis G, Lamont RJ. 2012. Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology. Mol. Oral Microbiol. 27:409-419. http://dx .doi.org/10.1111/j.2041-1014.2012.00663.x.
    • (2012) Mol. Oral Microbiol. , vol.27 , pp. 409-419
    • Hajishengallis, G.1    Lamont, R.J.2
  • 17
    • 67349111091 scopus 로고    scopus 로고
    • Synergism of Toll-like receptor 2 (TLR2), TLR4, and TLR6 ligation on the production of tumor necrosis factor (TNF)-alpha in a spontaneous arthritis animal model of interleukin (IL)-1 receptor antagonist-deficient mice
    • Jung YO, Cho ML, Lee SY, Oh HJ, Park JS, Park MK, Park MJ, Ju JH, Kim SI, Park SH, Kim HY, Min JK. 2009. Synergism of Toll-like receptor 2 (TLR2), TLR4, and TLR6 ligation on the production of tumor necrosis factor (TNF)-alpha in a spontaneous arthritis animal model of interleukin (IL)-1 receptor antagonist-deficient mice. Immunol. Lett. 123:138-143. http://dx.doi.org/10.1016/j.imlet.2009.03.004.
    • (2009) Immunol. Lett. , vol.123 , pp. 138-143
    • Jung, Y.O.1    Cho, M.L.2    Lee, S.Y.3    Oh, H.J.4    Park, J.S.5    Park, M.K.6    Park, M.J.7    Ju, J.H.8    Kim, S.I.9    Park, S.H.10    Kim, H.Y.11    Min, J.K.12
  • 18
    • 84904389334 scopus 로고    scopus 로고
    • 19 March TLR- mediated STAT3 and ERK activation controls IL-10 secretion by human B cells
    • Liu BS, Cao Y, Huizinga TW, Hafler DA, Toes RE. 19 March 2014. TLR-mediated STAT3 and ERK activation controls IL-10 secretion by human B cells. Eur. J. Immunol. http://dx.doi.org/10.1002/eji.201344341.
    • (2014) Eur. J. Immunol.
    • Liu, B.S.1    Cao, Y.2    Huizinga, T.W.3    Hafler, D.A.4    Toes, R.E.5
  • 19
    • 33749355639 scopus 로고    scopus 로고
    • TLR agonists promote ERK-mediated preferential IL-10 production of regulatory dendritic cells (diffDCs), leading to NK-cell activation
    • Qian C, Jiang X, An H, Yu Y, Guo Z, Liu S, Xu H, Cao X. 2006. TLR agonists promote ERK-mediated preferential IL-10 production of regulatory dendritic cells (diffDCs), leading to NK-cell activation. Blood 108: 2307-2315. http://dx.doi.org/10.1182/blood-2006-03-005595.
    • (2006) Blood , vol.108 , pp. 2307-2315
    • Qian, C.1    Jiang, X.2    An, H.3    Yu, Y.4    Guo, Z.5    Liu, S.6    Xu, H.7    Cao, X.8
  • 20
    • 0033599563 scopus 로고    scopus 로고
    • A new member of tumor necrosis factor ligand family, ODF/OPGL/TRANCE/RANKL, regulates osteoclast differentiation and function
    • Takahashi N, Udagawa N, Suda T. 1999. A new member of tumor necrosis factor ligand family, ODF/OPGL/TRANCE/RANKL, regulates osteoclast differentiation and function. Biochem. Biophys. Res. Commun. 256:449-455. http://dx.doi.org/10.1006/bbrc.1999.0252.
    • (1999) Biochem. Biophys. Res. Commun. , vol.256 , pp. 449-455
    • Takahashi, N.1    Udagawa, N.2    Suda, T.3
  • 21
    • 79959902674 scopus 로고    scopus 로고
    • TLR2- dependent modulation of osteoclastogenesis by Porphyromonas gingivalis through differential induction of NFATc1 and NFkappaB
    • Zhang P, Liu J, Xu Q, Harber G, Feng X, Michalek SM, Katz J. 2011. TLR2-dependent modulation of osteoclastogenesis by Porphyromonas gingivalis through differential induction of NFATc1 and NFkappaB. J. Biol. Chem. 286:24159 -24169. http://dx.doi.org/10.1074 /jbc.M110.198085.
    • (2011) J. Biol. Chem. , vol.286 , pp. 24159-24169
    • Zhang, P.1    Liu, J.2    Xu, Q.3    Harber, G.4    Feng, X.5    Michalek, S.M.6    Katz, J.7
  • 22
    • 33845462504 scopus 로고    scopus 로고
    • Cutting edge: TLR2 is required for the innate response to Porphyromonas gingivalis: activation leads to bacterial persistence and TLR2 deficiency attenuates induced alveolar bone resorption
    • Burns E, Bachrach G, Shapira L, Nussbaum G. 2006. Cutting edge: TLR2 is required for the innate response to Porphyromonas gingivalis: activation leads to bacterial persistence and TLR2 deficiency attenuates induced alveolar bone resorption. J. Immunol. 177:8296-8300. http://dx.doi.org /10.4049/jimmunol.177.12.8296.
    • (2006) J. Immunol. , vol.177 , pp. 8296-8300
    • Burns, E.1    Bachrach, G.2    Shapira, L.3    Nussbaum, G.4
  • 23
    • 39149116741 scopus 로고    scopus 로고
    • Macrophageelicited osteoclastogenesis in response to bacterial stimulation requires Toll-like receptor 2-dependent tumor necrosis factor-alpha production
    • Ukai T, Yumoto H, Gibson FC, 3rd, Genco CA. 2008. Macrophageelicited osteoclastogenesis in response to bacterial stimulation requires Toll-like receptor 2-dependent tumor necrosis factor-alpha production. Infect. Immun. 76:812-819. http://dx.doi.org/10.1128/IAI.01241-07.
    • (2008) Infect. Immun. , vol.76 , pp. 812-819
    • Ukai, T.1    Yumoto, H.2    Gibson III, F.C.3    Genco, C.A.4
  • 24
    • 84872725017 scopus 로고    scopus 로고
    • Macrophage-specific TLR2 signaling mediates pathogen-induced TNF-dependent inflammatory oral bone loss
    • Papadopoulos G, Weinberg EO, Massari P, Gibson FC, 3rd, Wetzler LM, Morgan EF, Genco CA. 2013. Macrophage-specific TLR2 signaling mediates pathogen-induced TNF-dependent inflammatory oral bone loss. J. Immunol. 190:1148-1157. http://dx.doi.org/10.4049/jimmunol .1202511.
    • (2013) J. Immunol. , vol.190 , pp. 1148-1157
    • Papadopoulos, G.1    Weinberg, E.O.2    Massari, P.3    Gibson III, F.C.4    Wetzler, L.M.5    Morgan, E.F.6    Genco, C.A.7
  • 25
    • 22344433900 scopus 로고    scopus 로고
    • Porphyromonas gingivalis lipopolysaccharide displays functionally diverse interactions with the innate host defense system
    • Bainbridge BW, Coats SR, Darveau RP. 2002. Porphyromonas gingivalis lipopolysaccharide displays functionally diverse interactions with the innate host defense system. Ann. Periodontol. 7:29-37. http://dx.doi.org/10 .1902/annals.2002.7.1.29.
    • (2002) Ann. Periodontol. , vol.7 , pp. 29-37
    • Bainbridge, B.W.1    Coats, S.R.2    Darveau, R.P.3
  • 26
    • 4544337512 scopus 로고    scopus 로고
    • Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both Toll-like receptors 2 and 4
    • Darveau RP, Pham TT, Lemley K, Reife RA, Bainbridge BW, Coats SR, Howald WN, Way SS, Hajjar AM. 2004. Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both Toll-like receptors 2 and 4. Infect. Immun. 72:5041-5051. http://dx.doi.org/10.1128/IAI.72.9.5041-5051.2004.
    • (2004) Infect. Immun. , vol.72 , pp. 5041-5051
    • Darveau, R.P.1    Pham, T.T.2    Lemley, K.3    Reife, R.A.4    Bainbridge, B.W.5    Coats, S.R.6    Howald, W.N.7    Way, S.S.8    Hajjar, A.M.9
  • 27
    • 67650394363 scopus 로고    scopus 로고
    • Requirement of TLR4 and CD14 in dendritic cell activation by hemagglutinin B from Porphyromonas gingivalis
    • Gaddis DE, Michalek SM, Katz J. 2009. Requirement of TLR4 and CD14 in dendritic cell activation by hemagglutinin B from Porphyromonas gingivalis. Mol. Immunol. 46:2493-2504. http://dx.doi.org /10.1016/j.molimm.2009.05.022.
    • (2009) Mol. Immunol. , vol.46 , pp. 2493-2504
    • Gaddis, D.E.1    Michalek, S.M.2    Katz, J.3
  • 29
    • 34547640077 scopus 로고    scopus 로고
    • Periodontal bacterial DNA suppresses the immune response to mutans streptococcal glucosyltransferase
    • Taubman MA, Han X, Larosa KB, Socransky SS, Smith DJ. 2007. Periodontal bacterial DNA suppresses the immune response to mutans streptococcal glucosyltransferase. Infect. Immun. 75:4088-4096. http: //dx.doi.org/10.1128/IAI.00623-07.
    • (2007) Infect. Immun. , vol.75 , pp. 4088-4096
    • Taubman, M.A.1    Han, X.2    Larosa, K.B.3    Socransky, S.S.4    Smith, D.J.5
  • 30
    • 47749153335 scopus 로고    scopus 로고
    • Aggregation behavior of an ultra-pure lipo-polysaccharide that stimulates TLR-4 receptors
    • Sasaki H, White SH. 2008. Aggregation behavior of an ultra-pure lipo-polysaccharide that stimulates TLR-4 receptors. Biophys. J. 95:986-993. http://dx.doi.org/10.1529/biophysj.108.129197.
    • (2008) Biophys. J. , vol.95 , pp. 986-993
    • Sasaki, H.1    White, S.H.2
  • 31
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S, Takeda K. 2004. Toll-like receptor signalling. Nat. Rev. Immunol. 4:499-511. http://dx.doi.org/10.1038/nri1391.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 32
    • 84880046627 scopus 로고    scopus 로고
    • Optimization of the ligature-induced periodontitis model in mice
    • Abe T, Hajishengallis G. 2013. Optimization of the ligature-induced periodontitis model in mice. J. Immunol. Methods 394:49-54. http://dx .doi.org/10.1016/j.jim.2013.05.002.
    • (2013) J. Immunol. Methods , vol.394 , pp. 49-54
    • Abe, T.1    Hajishengallis, G.2
  • 34
    • 0141532262 scopus 로고    scopus 로고
    • Toll-like receptor signaling
    • Akira S. 2003. Toll-like receptor signaling. J. Biol. Chem. 278:38105-38108. http://dx.doi.org/10.1074/jbc.R300028200.
    • (2003) J. Biol. Chem. , vol.278 , pp. 38105-38108
    • Akira, S.1
  • 35
    • 0035381253 scopus 로고    scopus 로고
    • Porphyromonas gingivalis lipopolysaccharide: an unusual pattern recognition receptor ligand for the innate host defense system
    • Bainbridge BW, Darveau RP. 2001. Porphyromonas gingivalis lipopolysaccharide: an unusual pattern recognition receptor ligand for the innate host defense system. Acta Odontol. Scand. 59:131-138. http://dx.doi.org /10.1080/000163501750266710.
    • (2001) Acta Odontol. Scand. , vol.59 , pp. 131-138
    • Bainbridge, B.W.1    Darveau, R.P.2
  • 36
    • 43849098061 scopus 로고    scopus 로고
    • Cytokine induction by pyrogens: comparison of whole blood, mononuclear cells, and TLRtransfectants
    • Kikkert R, de Groot ER, Aarden LA. 2008. Cytokine induction by pyrogens: comparison of whole blood, mononuclear cells, and TLRtransfectants. J. Immunol. Methods 336:45-55. http://dx.doi.org/10.1016 /j.jim.2008.03.010.
    • (2008) J. Immunol. Methods , vol.336 , pp. 45-55
    • Kikkert, R.1    de Groot, E.R.2    Aarden, L.A.3
  • 37
    • 34347204471 scopus 로고    scopus 로고
    • Chemical structure and immunobiological activity of Porphyromonas gingivalis lipid A
    • Ogawa T, Asai Y, Makimura Y, Tamai R. 2007. Chemical structure and immunobiological activity of Porphyromonas gingivalis lipid A. Front. Biosci. 12:3795-3812. http://dx.doi.org/10.2741/2353.
    • (2007) Front. Biosci. , vol.12 , pp. 3795-3812
    • Ogawa, T.1    Asai, Y.2    Makimura, Y.3    Tamai, R.4
  • 38
    • 84874904949 scopus 로고    scopus 로고
    • Tetra- and penta-acylated lipid A structures of Porphyromonas gingivalis LPS differentially activate TLR4-mediated NF-kappaB signal transduction cascade and immuno-inflammatory response in human gingival fibroblasts
    • Herath TD, Darveau RP, Seneviratne CJ, Wang CY, Wang Y, Jin L. 2013. Tetra- and penta-acylated lipid A structures of Porphyromonas gingivalis LPS differentially activate TLR4-mediated NF-kappaB signal transduction cascade and immuno-inflammatory response in human gingival fibroblasts. PLoS One 8:e58496. http://dx.doi.org/10.1371/journal.pone .0058496.
    • (2013) PLoS One , vol.8 , pp. e58496
    • Herath, T.D.1    Darveau, R.P.2    Seneviratne, C.J.3    Wang, C.Y.4    Wang, Y.5    Jin, L.6
  • 39
    • 79956199473 scopus 로고    scopus 로고
    • TLR4 signaling via MyD88 and TRIF differentially shape the CD4 T cell response to Porphyromonas gingivalis hemagglutinin B
    • Gaddis DE, Michalek SM, Katz J. 2011. TLR4 signaling via MyD88 and TRIF differentially shape the CD4 T cell response to Porphyromonas gingivalis hemagglutinin B. J. Immunol. 186:5772-5783. http://dx.doi.org /10.4049/jimmunol.1003192.
    • (2011) J. Immunol. , vol.186 , pp. 5772-5783
    • Gaddis, D.E.1    Michalek, S.M.2    Katz, J.3
  • 40
    • 84877795867 scopus 로고    scopus 로고
    • Porphyromonas gingivalis infection-associated periodontal bone resorption is dependent on receptor activator of NF-kappaB ligand
    • Han X, Lin X, Yu X, Lin J, Kawai T, LaRosa KB, Taubman MA. 2013. Porphyromonas gingivalis infection-associated periodontal bone resorption is dependent on receptor activator of NF-kappaB ligand. Infect. Immun. 81:1502-1509. http://dx.doi.org/10.1128/IAI.00043-13.
    • (2013) Infect. Immun. , vol.81 , pp. 1502-1509
    • Han, X.1    Lin, X.2    Yu, X.3    Lin, J.4    Kawai, T.5    LaRosa, K.B.6    Taubman, M.A.7
  • 41
    • 79251502922 scopus 로고    scopus 로고
    • Antibody to receptor activator of NF-kappaB ligand ameliorates T cell-mediated periodontal bone resorption
    • Lin X, Han X, Kawai T, Taubman MA. 2011. Antibody to receptor activator of NF-kappaB ligand ameliorates T cell-mediated periodontal bone resorption. Infect. Immun. 79:911-917. http://dx.doi.org/10.1128 /IAI.00944-10.
    • (2011) Infect. Immun. , vol.79 , pp. 911-917
    • Lin, X.1    Han, X.2    Kawai, T.3    Taubman, M.A.4
  • 42
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O. 2006. Pathogen recognition and innate immunity. Cell 124:783- 801. http://dx.doi.org/10.1016/j.cell .2006.02.015.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 43
    • 84866739329 scopus 로고    scopus 로고
    • Oxidized LDLs inhibit TLR-induced IL-10 production by monocytes: a new aspect of pathogen-accelerated atherosclerosis
    • Bzowska M, Nogiec A, Skrzeczynska-Moncznik J, Mickowska B, Guzik K, Pryjma J. 2012. Oxidized LDLs inhibit TLR-induced IL-10 production by monocytes: a new aspect of pathogen-accelerated atherosclerosis. Inflammation 35:1567-1584. http://dx.doi.org/10.1007 /s10753-012-9472-3.
    • (2012) Inflammation , vol.35 , pp. 1567-1584
    • Bzowska, M.1    Nogiec, A.2    Skrzeczynska-Moncznik, J.3    Mickowska, B.4    Guzik, K.5    Pryjma, J.6
  • 44
    • 79952284334 scopus 로고    scopus 로고
    • C5a controls TLR-induced IL-10 and IL-12 production independent of phosphoinositide 3-kinase
    • Okazaki N, Hazeki K, Izumi T, Nigorikawa K, Hazeki O. 2011. C5a controls TLR-induced IL-10 and IL-12 production independent of phosphoinositide 3-kinase. J. Biochem. 149:265-274. http://dx.doi.org/10 .1093/jb/mvq136.
    • (2011) J. Biochem. , vol.149 , pp. 265-274
    • Okazaki, N.1    Hazeki, K.2    Izumi, T.3    Nigorikawa, K.4    Hazeki, O.5
  • 45
    • 77953411618 scopus 로고    scopus 로고
    • MicroRNA-466l upregulates IL-10 expression in TLR-triggered macrophages by antagonizing RNA-binding protein tristetraprolin-mediated IL-10 mRNA degradation
    • Ma F, Liu X, Li D, Wang P, Li N, Lu L, Cao X. 2010. MicroRNA-466l upregulates IL-10 expression in TLR-triggered macrophages by antagonizing RNA-binding protein tristetraprolin-mediated IL-10 mRNA degradation. J. Immunol. 184:6053- 6059. http://dx.doi.org/10.4049 /jimmunol.0902308.
    • (2010) J. Immunol. , vol.184 , pp. 6053-6059
    • Ma, F.1    Liu, X.2    Li, D.3    Wang, P.4    Li, N.5    Lu, L.6    Cao, X.7
  • 46
    • 34248148098 scopus 로고    scopus 로고
    • Enhanced IL-10 production by TLR4- and TLR2-primed dendritic cells upon TLR restimulation
    • Yanagawa Y, Onoe K. 2007. Enhanced IL-10 production by TLR4- and TLR2-primed dendritic cells upon TLR restimulation. J. Immunol. 178: 6173-6180. http://dx.doi.org/10.4049/jimmunol.178.10.6173.
    • (2007) J. Immunol , vol.178 , pp. 6173-6180
    • Yanagawa, Y.1    Onoe, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.