Aggregatibacter actinomycetemcomitans outer membrane vesicles are internalized in human host cells and trigger NOD1- and NOD2-dependent NF-κB activation

Infection and Immunity

Volumn 82, Issue 10, 2014, Pages 4034-4046

  Thay, Bernard ^a   Damm, Anna ^b   Kufer, Thomas A ^b   Wai, Sun Nyunt ^a   Oscarsson, Jan ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; BACTERIUM ANTIBODY; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CASPASE RECRUITMENT DOMAIN PROTEIN 4; FLUORESCENT DYE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEPTIDOGLYCAN; BACTERIAL PROTEIN; NOD1 PROTEIN, HUMAN; NOD2 PROTEIN, HUMAN;

AGGREGATIBACTER ACTINOMYCETEMCOMITANS; ANTIGEN DETECTION; ARTICLE; BONE MARROW CELL; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM; EXPOSURE; FEMALE; FIBROBLAST; GINGIVA; GINGIVAL FIBROBLAST; HEK293 CELL LINE; HELA CELL LINE; HOST CELL; HUMAN; HUMAN CELL; IMMUNOELECTRON MICROSCOPY; INFLAMMATION; INNATE IMMUNITY; INTERNALIZATION; MEMBRANE VESICLE; NONHUMAN; OUTER MEMBRANE; OUTER MEMBRANE VESICLE; SEROTYPE; CELL LINE; ENDOCYTOSIS; EPITHELIUM CELL; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; SECRETORY VESICLE;

AGGREGATIBACTER ACTINOMYCETEMCOMITANS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELL LINE; ENDOCYTOSIS; EPITHELIAL CELLS; FIBROBLASTS; HOST-PATHOGEN INTERACTIONS; HUMANS; MICROSCOPY, CONFOCAL; MICROSCOPY, IMMUNOELECTRON; NF-KAPPA B; NOD1 SIGNALING ADAPTOR PROTEIN; NOD2 SIGNALING ADAPTOR PROTEIN; SECRETORY VESICLES;

EID: 84907103994     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01980-14     Document Type: Article

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