Perivascular adipose tissue-derived leptin promotes vascular smooth muscle cell phenotypic switching via p38 mitogen-activated protein kinase in metabolic syndrome rats

Experimental Biology and Medicine

Volumn 239, Issue 8, 2014, Pages 954-965

  Li, Hao ^a   Wang, Ya Ping ^b   Zhang, Li Na ^a   Tian, Gang ^a  

^a THE FIRST AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

^b SHAANXI PROVINCIAL PEOPLE S HOSPITAL   (China)

Author keywords

leptin; metabolic syndrome; p38 mitogen activated protein kinases; Perivascular adipose tissue; phenotypic switching; vascular smooth muscle cell

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL) IMIDAZOLE; ALPHA SMOOTH MUSCLE ACTIN; AORTIC LEPTIN RECEPTOR; BIOLOGICAL MARKER; CALPONIN; CHOLESTEROL; CYCLINE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LEPTIN; LEPTIN RECEPTOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MITOGEN ACTIVATED PROTEIN KINASE P38; PERIVASCULAR ADIPOSE TISSUE DERIVED LEPTIN; PROTEIN SERINE THREONINE KINASE; SMOOTH MUSCLE MYOSIN HEAVY CHAIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL WALL THICKNESS; ARTICLE; BLOOD VESSEL PARAMETERS; BODY MASS; CELL DIFFERENTIATION; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GLUCOSE TOLERANCE TEST; HYPERGLYCEMIA; HYPERLIPIDEMIA; HYPERTENSION; IMMUNOFLUORESCENCE TEST; INSULIN RESISTANCE; LUMEN DIAMETER; MALE; MEAN ARTERIAL PRESSURE; METABOLIC SYNDROME X; NONHUMAN; OBESITY; PHENOTYPIC VARIATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; SYSTOLIC BLOOD PRESSURE; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

EID: 84907072041     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/1535370214527903     Document Type: Article

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