HDAC inhibitors and immunotherapy; A double edged sword?

Oncotarget

Volumn 5, Issue 16, 2014, Pages 6558-6572

  Kroesen, Michiel ^a,b   Gielen, Paul R ^a   Brok, Ingrid C ^a   Armandari, Inna ^a   Hoogerbrugge, Peter M ^b,c   Adema, Gosse J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c Princes Ma xima Center for Pediatric Oncology   (Netherlands)

Author keywords

Cancer; HDAC inhibitor; Immunocombination therapy; Immunotherapy

Indexed keywords

B7 ANTIGEN; BCG VACCINE; BETA INTERFERON; DACINOSTAT; DEPSIPEPTIDE; ENTINOSTAT; GIVINOSTAT; HISTONE DEACETYLASE INHIBITOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MIGRATION INHIBITION FACTOR; NATURAL KILLER CELL RECEPTOR NKG2D; PANOBINOSTAT; TRICHOSTATIN A; TUMOR ANTIGEN; VALPROIC ACID; VORINOSTAT;

ADAPTIVE IMMUNITY; ANTIGEN PRESENTING CELL; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER IMMUNOTHERAPY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DEATH; CELL VIABILITY; CELLULAR IMMUNITY; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CROSS PRESENTATION; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; EFFECTOR CELL; HUMAN; IMMUNOCOMPETENT CELL; IMMUNOGENIC CELL DEATH; IMMUNOMODULATION; IN VIVO STUDY; MOLECULAR DYNAMICS; MYELOID DERIVED SUPPRESSOR CELL; NATURAL KILLER CELL; NONHUMAN; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TUMOR ASSOCIATED LEUKOCYTE; TUMOR CELL; TUMOR CELL RECOGNITION; ANIMAL; CHEMOPROPHYLAXIS; ENZYMOLOGY; IMMUNOLOGY; IMMUNOTHERAPY; NEOPLASMS; PROCEDURES;

ANIMALS; CHEMOPREVENTION; HISTONE DEACETYLASE INHIBITORS; HUMANS; IMMUNOTHERAPY; NEOPLASMS;

EID: 84907068045     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2289     Document Type: Article

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