-
1
-
-
36049028058
-
New nomenclature for chromatin-modifying enzymes
-
DOI 10.1016/j.cell.2007.10.039, PII S0092867407013591
-
Allis CD et al (2007) New nomenclature for chromatin-modifying enzymes. Cell 131: 633-636 (Pubitemid 350089969)
-
(2007)
Cell
, vol.131
, Issue.4
, pp. 633-636
-
-
Allis, C.D.1
Berger, S.L.2
Cote, J.3
Dent, S.4
Jenuwien, T.5
Kouzarides, T.6
Pillus, L.7
Reinberg, D.8
Shi, Y.9
Shiekhattar, R.10
Shilatifard, A.11
Workman, J.12
Zhang, Y.13
-
2
-
-
15044358494
-
Reading signals on the nucleosome with a new nomenclature for modi fi ed histones
-
Turner BM (2005) Reading signals on the nucleosome with a new nomenclature for modi fi ed histones. Nat Struct Mol Biol 12:110-112
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 110-112
-
-
Turner, B.M.1
-
3
-
-
1842411320
-
Crystal structure of the nucleosome core particle at 2.8 A resolution
-
DOI 10.1038/38444
-
Luger K, Mader AW, Richmond RK, Sargent DF, Richmond TJ (1997) Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature 389:251-260 (Pubitemid 27406632)
-
(1997)
Nature
, vol.389
, Issue.6648
, pp. 251-260
-
-
Luger, K.1
Mader, A.W.2
Richmond, R.K.3
Sargent, D.F.4
Richmond, T.J.5
-
4
-
-
80052970429
-
Mechanisms for ATP-dependent chromatin remodelling: The means to the end
-
Flaus A, Owen-Hughes T (2011) Mechanisms for ATP-dependent chromatin remodelling: the means to the end. FEBS J 278:3579-3595
-
(2011)
FEBS J
, vol.278
, pp. 3579-3595
-
-
Flaus, A.1
Owen-Hughes, T.2
-
5
-
-
79960302604
-
Linker histones incorporation maintains chromatin fi ber plasticity
-
Recouvreux P et al (2011) Linker histones incorporation maintains chromatin fi ber plasticity. Biophys J 100:2726-2735
-
(2011)
Biophys J
, vol.100
, pp. 2726-2735
-
-
Recouvreux, P.1
-
6
-
-
77949874234
-
Histone variants - Ancient wrap artists of the epigenome
-
Talbert PB, Henikoff S (2010) Histone variants - ancient wrap artists of the epigenome. Nat Rev Mol Cell Biol 11:264-275
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 264-275
-
-
Talbert, P.B.1
Henikoff, S.2
-
7
-
-
33847076849
-
Chromatin modifications and their function
-
DOI 10.1016/j.cell.2007.02.005, PII S0092867407001845
-
Kouzarides T (2007) Chromatin modi fi cations and their function. Cell 128:693-705 (Pubitemid 46273577)
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 693-705
-
-
Kouzarides, T.1
-
8
-
-
84862664108
-
Identi fi cation and pro fi ling of salinity stress-responsive proteins in Sorghum bicolor seedlings
-
Ngara R, Ndimba R, Borch-Jensen J, Jensen ON, Ndimba B (2012) Identi fi cation and pro fi ling of salinity stress-responsive proteins in Sorghum bicolor seedlings. J Proteomics 75: 4139-4150
-
(2012)
J Proteomics
, vol.75
, pp. 4139-4150
-
-
Ngara, R.1
Ndimba, R.2
Borch-Jensen, J.3
Jensen, O.N.4
Ndimba, B.5
-
9
-
-
80054818714
-
Modi fi cation of histones by sugar beta-N-acetylglucosamine (GlcNAc) occurs on multiple residues, including histone H3 serine 10, and is cell cycle-regulated
-
Zhang S, Roche K, Nasheuer HP, Lowndes NF (2011) Modi fi cation of histones by sugar beta-N-acetylglucosamine (GlcNAc) occurs on multiple residues, including histone H3 serine 10, and is cell cycle-regulated. J Biol Chem 286:37483-37495
-
(2011)
J Biol Chem
, vol.286
, pp. 37483-37495
-
-
Zhang, S.1
Roche, K.2
Nasheuer, H.P.3
Lowndes, N.F.4
-
10
-
-
80052942443
-
Identi fi cation of 67 histone marks and histone lysine crotonylation as a new type of histone modi fi cation
-
Tan M et al (2011) Identi fi cation of 67 histone marks and histone lysine crotonylation as a new type of histone modi fi cation. Cell 146:1016-1028
-
(2011)
Cell
, vol.146
, pp. 1016-1028
-
-
Tan, M.1
-
11
-
-
34548312353
-
Histone proteomics and the epigenetic regulation of nucleosome mobility
-
DOI 10.1586/14789450.4.4.465
-
Cosgrove MS (2007) Histone proteomics and the epigenetic regulation of nucleosome mobility. Expert Rev Proteomics 4:465-478 (Pubitemid 47347595)
-
(2007)
Expert Review of Proteomics
, vol.4
, Issue.4
, pp. 465-478
-
-
Cosgrove, M.S.1
-
12
-
-
27644467857
-
Insights into the role of histone H3 and histone H4 core modifiable residues in Saccharomyces cerevisiae
-
DOI 10.1128/MCB.25.22.10060-10070.2005
-
Hyland EM et al (2005) Insights into the role of histone H3 and histone H4 core modi fi able residues in Saccharomyces cerevisiae. Mol Cell Biol 25:10060-10070 (Pubitemid 41572751)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.22
, pp. 10060-10070
-
-
Hyland, E.M.1
Cosgrove, M.S.2
Molina, H.3
Wang, D.4
Pandey, A.5
Cottee, R.J.6
Boeke, J.D.7
-
13
-
-
18844413266
-
Acetylation in histone H3 globular domain regulates gene expression in yeast
-
DOI 10.1016/j.cell.2005.03.011, PII S0092867405002837
-
Xu F, Zhang K, Grunstein M (2005) Acetylation in histone H3 globular domain regulates gene expression in yeast. Cell 121:375-385 (Pubitemid 40692298)
-
(2005)
Cell
, vol.121
, Issue.3
, pp. 375-385
-
-
Xu, F.1
Zhang, K.2
Grunstein, M.3
-
14
-
-
22444448143
-
A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response
-
DOI 10.1038/nature03714
-
Masumoto H, Hawke D, Kobayashi R, Verreault A (2005) A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response. Nature 436:294-298 (Pubitemid 41021284)
-
(2005)
Nature
, vol.436
, Issue.7048
, pp. 294-298
-
-
Masumoto, H.1
Hawke, D.2
Kobayashi, R.3
Verreault, A.4
-
15
-
-
84855200286
-
DNA damage in the presence of chemical genotoxic agents induce acetylation of H3K56 and H4K16 but not H3K9 in mammalian cells
-
Vempati RK (2012) DNA damage in the presence of chemical genotoxic agents induce acetylation of H3K56 and H4K16 but not H3K9 in mammalian cells. Mol Biol Rep 39:303-308
-
(2012)
Mol Biol Rep
, vol.39
, pp. 303-308
-
-
Vempati, R.K.1
-
16
-
-
81755163074
-
Histone H3K56 acetylation, CAF1, and Rtt106 coordinate nucleosome assembly and stability of advancing replication forks
-
Clemente-Ruiz M, Gonzalez-Prieto R, Prado F (2011) Histone H3K56 acetylation, CAF1, and Rtt106 coordinate nucleosome assembly and stability of advancing replication forks. PLoS Genet 7:e1002376
-
(2011)
PLoS Genet
, vol.7
-
-
Clemente-Ruiz, M.1
Gonzalez-Prieto, R.2
Prado, F.3
-
17
-
-
77953727152
-
Structural characterization of H3K56Q nucleosomes and nucleosomal arrays
-
Watanabe S et al (2010) Structural characterization of H3K56Q nucleosomes and nucleosomal arrays. Biochim Biophys Acta 1799:480-486
-
(2010)
Biochim Biophys Acta
, vol.1799
, pp. 480-486
-
-
Watanabe, S.1
-
18
-
-
60549111235
-
Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells
-
Xie W et al (2009) Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Mol Cell 33:417-427
-
(2009)
Mol Cell
, vol.33
, pp. 417-427
-
-
Xie, W.1
-
20
-
-
34347363106
-
Histone tails and the H3 αN helix regulate nucleosome mobility and stability
-
DOI 10.1128/MCB.02229-06
-
Ferreira H, Somers J, Webster R, Flaus A, Owen-Hughes T (2007) Histone tails and the H3 alphaN helix regulate nucleosome mobility and stability. Mol Cell Biol 27:4037-4048 (Pubitemid 47011001)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.11
, pp. 4037-4048
-
-
Ferreira, H.1
Somers, J.2
Webster, R.3
Flaus, A.4
Owen-Hughes, T.5
-
21
-
-
0029739422
-
All four core histone N-termini contain sequences required for the repression of basal transcription in yeast
-
Lenfant F, Mann RK, Thomsen B, Ling X, Grunstein M (1996) All four core histone N-termini contain sequences required for the repression of basal transcription in yeast. EMBO J 15:3974-3985 (Pubitemid 26289807)
-
(1996)
EMBO Journal
, vol.15
, Issue.15
, pp. 3974-3985
-
-
Lenfant, F.1
Mann, R.K.2
Thomsen, B.3
Ling, X.4
Grunstein, M.5
-
22
-
-
0029878216
-
Yeast histone H3 and H4 amino termini are important for nucleosome assembly in vivo and in vitro: Redundant and position-independent functions in assembly but not in gene regulation
-
Ling X, Harkness TA, Schultz MC, Fisher-Adams G, Grunstein M (1996) Yeast histone H3 and H4 amino termini are important for nucleosome assembly in vivo and in vitro: redundant and position-independent functions in assembly but not in gene regulation. Genes Dev 10:686-699 (Pubitemid 26112423)
-
(1996)
Genes and Development
, vol.10
, Issue.6
, pp. 686-699
-
-
Ling, X.1
Harkness, T.A.A.2
Schultz, M.C.3
Fisher-Adams, G.4
Grunstein, M.5
-
23
-
-
17244368913
-
Genomic characterization reveals a simple histone H4 acetylation code
-
DOI 10.1073/pnas.0500136102
-
Dion MF, Altschuler SJ, Wu LF, Rando OJ (2005) Genomic characterization reveals a simple histone H4 acetylation code. Proc Natl Acad Sci USA 102:5501-5506 (Pubitemid 40530287)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.15
, pp. 5501-5506
-
-
Dion, M.F.1
Altschuler, S.J.2
Wu, L.F.3
Rando, O.J.4
-
24
-
-
0027525056
-
Decoding the nucleosome
-
DOI 10.1016/0092-8674(93)90673-E
-
Turner BM (1993) Decoding the nucleosome. Cell 75:5-8 (Pubitemid 23306015)
-
(1993)
Cell
, vol.75
, Issue.1
, pp. 5-8
-
-
Turner, B.M.1
-
25
-
-
0026566417
-
Histone H4 isoforms acetylated at speci fi c lysine residues de fi ne individual chromosomes and chromatin domains in Drosophila polytene nuclei
-
Turner BM, Birley AJ, Lavender J (1992) Histone H4 isoforms acetylated at speci fi c lysine residues de fi ne individual chromosomes and chromatin domains in Drosophila polytene nuclei. Cell 69:375-384
-
(1992)
Cell
, vol.69
, pp. 375-384
-
-
Turner, B.M.1
Birley, A.J.2
Lavender, J.3
-
26
-
-
80055074343
-
SnapShot: Histone readers
-
Kutateladze TG (2011) SnapShot: histone readers. Cell 146:842-842.e1
-
(2011)
Cell
, vol.146
-
-
Kutateladze, T.G.1
-
27
-
-
35848961668
-
How chromatin-binding modules interpret histone modifications: Lessons from professional pocket pickers
-
DOI 10.1038/nsmb1338, PII NSMB1338
-
Taverna SD, Li H, Ruthenburg AJ, Allis CD, Patel DJ (2007) How chromatin-binding modules interpret histone modi fi cations: lessons from professional pocket pickers. Nat Struct Mol Biol 14:1025-1040 (Pubitemid 350060344)
-
(2007)
Nature Structural and Molecular Biology
, vol.14
, Issue.11
, pp. 1025-1040
-
-
Taverna, S.D.1
Li, H.2
Ruthenburg, A.J.3
Allis, C.D.4
Patel, D.J.5
-
28
-
-
77449121100
-
Jmjd1a demethylase-regulated histone modi fi cation is essential for cAMPresponse element modulator-regulated gene expression and spermatogenesis
-
Liu Z et al (2010) Jmjd1a demethylase-regulated histone modi fi cation is essential for cAMPresponse element modulator-regulated gene expression and spermatogenesis. J Biol Chem 285:2758-2770
-
(2010)
J Biol Chem
, vol.285
, pp. 2758-2770
-
-
Liu, Z.1
-
29
-
-
78650734995
-
Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly
-
Canzio D et al (2011) Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly. Mol Cell 41:67-81
-
(2011)
Mol Cell
, vol.41
, pp. 67-81
-
-
Canzio, D.1
-
30
-
-
61349098460
-
Differential chromatin marking of introns and expressed exons by H3K36me3
-
Kolasinska-Zwierz P et al (2009) Differential chromatin marking of introns and expressed exons by H3K36me3. Nat Genet 41:376-381
-
(2009)
Nat Genet
, vol.41
, pp. 376-381
-
-
Kolasinska-Zwierz, P.1
-
31
-
-
3042858906
-
Heterochromatin and tri-methylated lysine 20 of histone H4 in animals
-
DOI 10.1242/jcs.01238
-
Kourmouli N et al (2004) Heterochromatin and tri-methylated lysine 20 of histone H4 in animals. J Cell Sci 117:2491-2501 (Pubitemid 38877845)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.12
, pp. 2491-2501
-
-
Kourmouli, N.1
Jeppesen, P.2
Mahadevhaiah, S.3
Burgoyne, P.4
Wu, R.5
Gilbert, D.M.6
Bongiorni, S.7
Prantera, G.8
Fanti, L.9
Pimpinelli, S.10
Shi, W.11
Fundele, R.12
Singh, P.B.13
-
32
-
-
33846983276
-
Polycomb/trithorax response elements and epigenetic memory of cell identity
-
Ringrose L, Paro R (2007) Polycomb/trithorax response elements and epigenetic memory of cell identity. Development 134:223-232
-
(2007)
Development
, vol.134
, pp. 223-232
-
-
Ringrose, L.1
Paro, R.2
-
33
-
-
2942610993
-
Tethering of HP1 proteins to chromatin is relieved by phospoacetylation of histone H3
-
DOI 10.1038/sj.embor.7400139
-
Mateescu B, England P, Halgand F, Yaniv M, Muchardt C (2004) Tethering of HP1 proteins to chromatin is relieved by phosphoacetylation of histone H3. EMBO Rep 5:490-496 (Pubitemid 38745040)
-
(2004)
EMBO Reports
, vol.5
, Issue.5
, pp. 490-496
-
-
Mateescu, B.1
England, P.2
Halgand, F.3
Yaniv, M.4
Muchardt, C.5
-
34
-
-
79955583542
-
Mapping and analysis of chromatin state dynamics in nine human cell types
-
Ernst J et al (2011) Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 473:43-49
-
(2011)
Nature
, vol.473
, pp. 43-49
-
-
Ernst, J.1
-
35
-
-
79953060951
-
Comprehensive analysis of the chromatin landscape in Drosophila melanogaster
-
Kharchenko PV et al (2011) Comprehensive analysis of the chromatin landscape in Drosophila melanogaster. Nature 471:480-485
-
(2011)
Nature
, vol.471
, pp. 480-485
-
-
Kharchenko, P.V.1
-
36
-
-
79951516056
-
A unique chromatin signature uncovers early developmental enhancers in humans
-
Rada-Iglesias A et al (2011) A unique chromatin signature uncovers early developmental enhancers in humans. Nature 470:279-283
-
(2011)
Nature
, vol.470
, pp. 279-283
-
-
Rada-Iglesias, A.1
-
37
-
-
33744800781
-
Computer modeling demonstrates that electrostatic attraction of nucleosomal DNA is mediated by histone tails
-
DOI 10.1529/biophysj.105.080226
-
Korolev N, Lyubartsev AP, Nordenskiold L (2006) Computer modeling demonstrates that electrostatic attraction of nucleosomal DNA is mediated by histone tails. Biophys J 90: 4305-4316 (Pubitemid 43830879)
-
(2006)
Biophysical Journal
, vol.90
, Issue.12
, pp. 4305-4316
-
-
Korolev, N.1
Lyubartsev, A.P.2
Nordenskiold, L.3
-
38
-
-
33644827669
-
Electrostatic interactions with histone tails
-
may bend linker DNA in chromatin
-
Perico A, La Penna G, Arcesi L (2006) Electrostatic interactions with histone tails may bend linker DNA in chromatin. Biopolymers 81:20-28
-
(2006)
Biopolymers
, vol.81
, pp. 20-28
-
-
Perico, A.1
La Penna, G.2
Arcesi, L.3
-
39
-
-
79953323462
-
Dot1 and histone H3K79 methylation in natural telomeric and HM silencing
-
Takahashi YH et al (2011) Dot1 and histone H3K79 methylation in natural telomeric and HM silencing. Mol Cell 42:118-126
-
(2011)
Mol Cell
, vol.42
, pp. 118-126
-
-
Takahashi, Y.H.1
-
40
-
-
52949107241
-
The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure
-
Jones B et al (2008) The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure. PLoS Genet 4:e1000190
-
(2008)
PLoS Genet
, vol.4
-
-
Jones, B.1
-
41
-
-
35348993743
-
Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination
-
Lee MG et al (2007) Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination. Science 318:447-450
-
(2007)
Science
, vol.318
, pp. 447-450
-
-
Lee, M.G.1
-
42
-
-
35148867907
-
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
-
DOI 10.1038/nature06145, PII NATURE06145
-
Agger K et al (2007) UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature 449:731-734 (Pubitemid 47552088)
-
(2007)
Nature
, vol.449
, Issue.7163
, pp. 731-734
-
-
Agger, K.1
Cloos, P.A.C.2
Christensen, J.3
Pasini, D.4
Rose, S.5
Rappsilber, J.6
Issaeva, I.7
Canaani, E.8
Salcini, A.E.9
Helin, K.10
-
43
-
-
80054910846
-
H3K4 tri-methylation provides an epigenetic signature of active enhancers
-
Pekowska A et al (2011) H3K4 tri-methylation provides an epigenetic signature of active enhancers. EMBO J 30:4198-4210
-
(2011)
EMBO J
, vol.30
, pp. 4198-4210
-
-
Pekowska, A.1
-
44
-
-
57149096220
-
Genome-wide relationship between histone H3 lysine 4 monoand tri-methylation and transcription factor binding
-
Robertson AG et al (2008) Genome-wide relationship between histone H3 lysine 4 monoand tri-methylation and transcription factor binding. Genome Res 18:1906-1917
-
(2008)
Genome Res
, vol.18
, pp. 1906-1917
-
-
Robertson, A.G.1
-
45
-
-
33846253247
-
Butyrate Induces Intestinal Sodium Absorption via Sp3-Mediated Transcriptional Up-Regulation of Epithelial Sodium Channels
-
DOI 10.1053/j.gastro.2006.10.033, PII S0016508506022670
-
Zeissig S et al (2007) Butyrate induces intestinal sodium absorption via Sp3-mediated transcriptional up-regulation of epithelial sodium channels. Gastroenterology 132:236-248 (Pubitemid 46108746)
-
(2007)
Gastroenterology
, vol.132
, Issue.1
, pp. 236-248
-
-
Zeissig, S.1
Fromm, A.2
Mankertz, J.3
Weiske, J.4
Zeitz, M.5
Fromm, M.6
Schulzke, J.7
-
47
-
-
0024422712
-
3
-
DOI 10.1016/0006-2952(89)90596-0
-
Tanaka Y, Bush KK, Klauck TM, Higgins PJ (1989) Enhancement of butyrate-induced differentiation of HT-29 human colon carcinoma cells by 1,25-dihydroxyvitamin D3. Biochem Pharmacol 38:3859-3865 (Pubitemid 19284038)
-
(1989)
Biochemical Pharmacology
, vol.38
, Issue.21
, pp. 3859-3865
-
-
Tanaka, Y.1
Bush, K.K.2
Klauck, T.M.3
Higgins, P.J.4
-
48
-
-
0037112360
-
The bioenergetic signature of cancer: A marker of tumor progression
-
Cuezva JM et al (2002) The bioenergetic signature of cancer: a marker of tumor progression. Cancer Res 62:6674-6681 (Pubitemid 35364137)
-
(2002)
Cancer Research
, vol.62
, Issue.22
, pp. 6674-6681
-
-
Cuezva, J.M.1
Krajewska, M.2
De Heredia, M.L.3
Krajewski, S.4
Santamaria, G.5
Kim, H.6
Zapata, J.M.7
Marusawa, H.8
Chamorro, M.9
Reed, J.C.10
-
49
-
-
0019883373
-
Warburg effect revisited: Merger of biochemistry and molecular biology
-
Racker E, Spector M (1981) Warburg effect revisited: merger of biochemistry and molecular biology. Science 213:303-307
-
(1981)
Science
, vol.213
, pp. 303-307
-
-
Racker, E.1
Spector, M.2
-
50
-
-
52649107626
-
Cancer cell metabolism: Warburg and beyond
-
Hsu PP, Sabatini DM (2008) Cancer cell metabolism: Warburg and beyond. Cell 134:703-707
-
(2008)
Cell
, vol.134
, pp. 703-707
-
-
Hsu, P.P.1
Sabatini, D.M.2
-
51
-
-
79953663708
-
Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells
-
Cavill R et al (2011) Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells. PLoS Comput Biol 7:e1001113
-
(2011)
PLoS Comput Biol
, vol.7
-
-
Cavill, R.1
-
52
-
-
79951529195
-
Integrated metabolome and transcriptome analysis of the NCI60 dataset
-
Su G, Burant CF, Beecher CW, Athey BD, Meng F (2011) Integrated metabolome and transcriptome analysis of the NCI60 dataset. BMC Bioinformatics 12(Suppl 1):S36
-
(2011)
BMC Bioinformatics
, vol.12
, Issue.SUPPL. 1
-
-
Su, G.1
Burant, C.F.2
Beecher, C.W.3
Athey, B.D.4
Meng, F.5
-
53
-
-
77954137469
-
Systems biology approaches to disease marker discovery
-
Sharon D, Chen R, Snyder M (2010) Systems biology approaches to disease marker discovery. Dis Markers 28:209-224
-
(2010)
Dis Markers
, vol.28
, pp. 209-224
-
-
Sharon, D.1
Chen, R.2
Snyder, M.3
-
54
-
-
62849083222
-
The emerging role of nuclear architecture in DNA repair and genome maintenance
-
Misteli T, Soutoglou E (2009) The emerging role of nuclear architecture in DNA repair and genome maintenance. Nat Rev Mol Cell Biol 10:243-254
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 243-254
-
-
Misteli, T.1
Soutoglou, E.2
-
55
-
-
21744457108
-
Global histone modification patterns predict risk of prostate cancer recurrence
-
DOI 10.1038/nature03672
-
Seligson DB et al (2005) Global histone modi fi cation patterns predict risk of prostate cancer recurrence. Nature 435:1262-1266 (Pubitemid 40943093)
-
(2005)
Nature
, vol.435
, Issue.7046
, pp. 1262-1266
-
-
Seligson, D.B.1
Horvath, S.2
Shi, T.3
Yu, H.4
Tze, S.5
Grunstein, M.6
Kurdistani, S.K.7
-
56
-
-
34347341770
-
Histone modifications as markers of cancer prognosis: A cellular view
-
DOI 10.1038/sj.bjc.6603844, PII 6603844
-
Kurdistani SK (2007) Histone modi fi cations as markers of cancer prognosis: a cellular view. Br J Cancer 97:1-5 (Pubitemid 47012099)
-
(2007)
British Journal of Cancer
, vol.97
, Issue.1
, pp. 1-5
-
-
Kurdistani, S.K.1
-
57
-
-
74249098871
-
Prognostic impact of H3K27me3 expression on locoregional progression after chemoradiotherapy in esophageal squamous cell carcinoma
-
He LR et al (2009) Prognostic impact of H3K27me3 expression on locoregional progression after chemoradiotherapy in esophageal squamous cell carcinoma. BMC Cancer 9:461
-
(2009)
BMC Cancer
, vol.9
, pp. 461
-
-
He, L.R.1
-
58
-
-
59149096527
-
Prognostic signi fi cance of global histone modi fi cations in resected squamous cell carcinoma of the esophagus
-
Tzao C et al (2009) Prognostic signi fi cance of global histone modi fi cations in resected squamous cell carcinoma of the esophagus. Mod Pathol 22:252-260
-
(2009)
Mod Pathol
, vol.22
, pp. 252-260
-
-
Tzao, C.1
-
59
-
-
36349017912
-
A polycomb repression signature in metastatic prostate cancer predicts cancer outcome
-
DOI 10.1158/0008-5472.CAN-07-2498
-
Yu J et al (2007) A polycomb repression signature in metastatic prostate cancer predicts cancer outcome. Cancer Res 67:10657-10663 (Pubitemid 350145890)
-
(2007)
Cancer Research
, vol.67
, Issue.22
, pp. 10657-10663
-
-
Yu, J.1
Yu, J.2
Rhodes, D.R.3
Tomlins, S.A.4
Cao, X.5
Chen, G.6
Mehra, R.7
Wang, X.8
Ghosh, D.9
Shah, R.B.10
Varambally, S.11
Pienta, K.J.12
Chinnaiyan, A.M.13
-
60
-
-
50249175130
-
Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers
-
Wei Y et al (2008) Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers. Mol Carcinog 47:701-706
-
(2008)
Mol Carcinog
, vol.47
, pp. 701-706
-
-
Wei, Y.1
-
61
-
-
55549103314
-
A model for transmission of the H3K27me3 epigenetic mark
-
Hansen KH et al (2008) A model for transmission of the H3K27me3 epigenetic mark. Nat Cell Biol 10:1291-1300
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1291-1300
-
-
Hansen, K.H.1
-
62
-
-
20144388146
-
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
-
Fraga MF et al (2005) Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet 37:391-400
-
(2005)
Nat Genet
, vol.37
, pp. 391-400
-
-
Fraga, M.F.1
-
63
-
-
32544452237
-
Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins
-
Tryndyak VP, Kovalchuk O, Pogribny IP (2006) Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins. Cancer Biol Ther 5:65-70 (Pubitemid 43234980)
-
(2006)
Cancer Biology and Therapy
, vol.5
, Issue.1
, pp. 65-70
-
-
Tryndyak, V.P.1
Kovalchuk, O.2
Pogribny, I.P.3
-
64
-
-
39649119288
-
The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma
-
Pfister S et al (2008) The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma. Int J Cancer 122:1207-1213
-
(2008)
Int J Cancer
, vol.122
, pp. 1207-1213
-
-
Fi, P.1
Ster, S.2
-
65
-
-
80054782483
-
The dual role of sirtuins in cancer
-
Bosch-Presegue L, Vaquero A (2011) The dual role of sirtuins in cancer. Genes Cancer 2:648-662
-
(2011)
Genes Cancer
, vol.2
, pp. 648-662
-
-
Bosch-Presegue, L.1
Vaquero, A.2
-
66
-
-
84867082035
-
Epigenetic cancer therapy: Rationales, targets and drugs
-
Dec 19. doi:10.1038/onc.2011.601
-
Rius M, Lyko F (2011) Epigenetic cancer therapy: rationales, targets and drugs. Oncogene Dec 19. doi:10.1038/onc.2011.601
-
(2011)
Oncogene
-
-
Rius, M.1
Lyko, F.2
-
67
-
-
33646142159
-
Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats
-
DOI 10.1093/carcin/bgi364
-
Pogribny IP et al (2006) Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats. Carcinogenesis 27:1180-1186 (Pubitemid 43985433)
-
(2006)
Carcinogenesis
, vol.27
, Issue.6
, pp. 1180-1186
-
-
Pogribny, I.P.1
Ross, S.A.2
Tryndyak, V.P.3
Pogribna, M.4
Poirier, L.A.5
Karpinets, T.V.6
-
68
-
-
75749102137
-
Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition
-
Lakshmikuttyamma A, Scott SA, DeCoteau JF, Geyer CR (2010) Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition. Oncogene 29:576-588
-
(2010)
Oncogene
, vol.29
, pp. 576-588
-
-
Lakshmikuttyamma, A.1
Scott, S.A.2
Decoteau, J.F.3
Geyer, C.R.4
-
69
-
-
65549113750
-
CBP/p300-mediated acetylation of histone H3 on lysine 56
-
Das C, Lucia MS, Hansen KC, Tyler JK (2009) CBP/p300-mediated acetylation of histone H3 on lysine 56. Nature 459:113-117
-
(2009)
Nature
, vol.459
, pp. 113-117
-
-
Das, C.1
Lucia, M.S.2
Hansen, K.C.3
Tyler, J.K.4
-
70
-
-
48249148195
-
Acetylation in the globular core of histone H3 on lysine-56 promotes chromatin disassembly during transcriptional activation
-
Williams SK, Truong D, Tyler JK (2008) Acetylation in the globular core of histone H3 on lysine-56 promotes chromatin disassembly during transcriptional activation. Proc Natl Acad Sci USA 105:9000-9005
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 9000-9005
-
-
Williams, S.K.1
Truong, D.2
Tyler, J.K.3
-
71
-
-
34548717647
-
Chromatin disassembly from the PHO5 promoter is essential for the recruitment of the general transcription machinery and coactivators
-
DOI 10.1128/MCB.00981-07
-
Adkins MW, Williams SK, Linger J, Tyler JK (2007) Chromatin disassembly from the PHO5 promoter is essential for the recruitment of the general transcription machinery and coactivators. Mol Cell Biol 27:6372-6382 (Pubitemid 47435744)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.18
, pp. 6372-6382
-
-
Adkins, M.W.1
Williams, S.K.2
Linger, J.3
Tyler, J.K.4
-
72
-
-
33745865934
-
Chromatin in pluripotent embryonic stem cells and differentiation
-
DOI 10.1038/nrm1938, PII NRM1938
-
Meshorer E, Misteli T (2006) Chromatin in pluripotent embryonic stem cells and differentiation. Nat Rev Mol Cell Biol 7:540-546 (Pubitemid 44036459)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.7
, pp. 540-546
-
-
Meshorer, E.1
Misteli, T.2
-
73
-
-
33947301272
-
Epigenetic signatures of stem-cell identity
-
DOI 10.1038/nrg2046, PII NRG2046
-
Spivakov M, Fisher AG (2007) Epigenetic signatures of stem-cell identity. Nat Rev Genet 8:263-271 (Pubitemid 46439288)
-
(2007)
Nature Reviews Genetics
, vol.8
, Issue.4
, pp. 263-271
-
-
Spivakov, M.1
Fisher, A.G.2
-
74
-
-
42049090788
-
Gone with the Wnt/Notch: Stem cells in laminopathies, progeria, and aging
-
DOI 10.1083/jcb.200802155
-
Meshorer E, Gruenbaum Y (2008) Gone with the Wnt/Notch: stem cells in laminopathies, progeria, and aging. J Cell Biol 181:9-13 (Pubitemid 351519758)
-
(2008)
Journal of Cell Biology
, vol.181
, Issue.1
, pp. 9-13
-
-
Meshorer, E.1
Gruenbaum, Y.2
-
75
-
-
35348982301
-
Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
-
DOI 10.1101/gad.1588207
-
Loh YH, Zhang W, Chen X, George J, Ng HH (2007) Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells. Genes Dev 21:2545-2557 (Pubitemid 47607666)
-
(2007)
Genes and Development
, vol.21
, Issue.20
, pp. 2545-2557
-
-
Loh, Y.-H.1
Zhang, W.2
Chen, X.3
George, J.4
Ng, H.-H.5
-
76
-
-
36248990248
-
SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron
-
DOI 10.1038/nature06270, PII NATURE06270
-
Jepsen K et al (2007) SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron. Nature 450:415-419 (Pubitemid 350126746)
-
(2007)
Nature
, vol.450
, Issue.7168
, pp. 415-419
-
-
Jepsen, K.1
Solum, D.2
Zhou, T.3
McEvilly, R.J.4
Kim, H.-J.5
Glass, C.K.6
Hermanson, O.7
Rosenfeld, M.G.8
-
77
-
-
34848864644
-
Epidermal stem cells are defined by global histone modi fi cations that are altered by Myc-induced differentiation
-
Frye M, Fisher AG, Watt FM (2007) Epidermal stem cells are defined by global histone modi fi cations that are altered by Myc-induced differentiation. PLoS One 2:e763
-
(2007)
PLoS One
, vol.2
-
-
Frye, M.1
Fisher, A.G.2
Watt, F.M.3
-
78
-
-
33744954457
-
Differential expression of selected histone modi fi er genes in human solid cancers
-
Ozdag H et al (2006) Differential expression of selected histone modi fi er genes in human solid cancers. BMC Genomics 7:90
-
(2006)
BMC Genomics
, vol.7
, pp. 90
-
-
Ozdag, H.1
-
79
-
-
56649103900
-
Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells
-
Watanabe H et al (2008) Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells. Cancer Cell Int 8:15
-
(2008)
Cancer Cell Int
, vol.8
, pp. 15
-
-
Watanabe, H.1
-
80
-
-
76749139057
-
The histone demethylase UTX enables RB-dependent cell fate control
-
Wang JK et al (2010) The histone demethylase UTX enables RB-dependent cell fate control. Genes Dev 24:327-332
-
(2010)
Genes Dev
, vol.24
, pp. 327-332
-
-
Wang, J.K.1
-
81
-
-
67349203626
-
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer
-
van Haaften G et al (2009) Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer. Nat Genet 41:521-523
-
(2009)
Nat Genet
, vol.41
, pp. 521-523
-
-
Van Haaften, G.1
-
82
-
-
70349464819
-
P21(WAF1) gene promoter is epigenetically silenced by CTIP2 and SUV39H1
-
Cherrier T et al (2009) p21(WAF1) gene promoter is epigenetically silenced by CTIP2 and SUV39H1. Oncogene 28:3380-3389
-
(2009)
Oncogene
, vol.28
, pp. 3380-3389
-
-
Cherrier, T.1
-
83
-
-
58949097017
-
Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha
-
Pollard PJ et al (2008) Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha. Biochem J 416:387-394
-
(2008)
Biochem J
, vol.416
, pp. 387-394
-
-
Pollard, P.J.1
-
84
-
-
58349101326
-
Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells
-
Scharer CD et al (2009) Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells. Cancer Res 69:709-717
-
(2009)
Cancer Res
, vol.69
, pp. 709-717
-
-
Scharer, C.D.1
-
85
-
-
18644382388
-
The polycomb group protein EZH2 is involved in progression of prostate cancer
-
Varambally S et al (2002) The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature 419:624-629
-
(2002)
Nature
, vol.419
, pp. 624-629
-
-
Varambally, S.1
-
86
-
-
44349131472
-
Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation
-
DOI 10.1038/ng.159, PII NG159
-
Kondo Y et al (2008) Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation. Nat Genet 40:741-750 (Pubitemid 351748874)
-
(2008)
Nature Genetics
, vol.40
, Issue.6
, pp. 741-750
-
-
Kondo, Y.1
Shen, L.2
Cheng, A.S.3
Ahmed, S.4
Boumber, Y.5
Charo, C.6
Yamochi, T.7
Urano, T.8
Furukawa, K.9
Kwabi-Addo, B.10
Gold, D.L.11
Sekido, Y.12
Huang, T.H.-M.13
Issa, J.-P.J.14
-
87
-
-
77749297990
-
An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB
-
Min J et al (2010) An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB. Nat Med 16:286-294
-
(2010)
Nat Med
, vol.16
, pp. 286-294
-
-
Min, J.1
-
88
-
-
11144332565
-
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
-
DOI 10.1016/j.cell.2004.12.012, PII S0092867404011997
-
Shi Y et al (2004) Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119:941-953 (Pubitemid 40037608)
-
(2004)
Cell
, vol.119
, Issue.7
, pp. 941-953
-
-
Shi, Y.1
Lan, F.2
Matson, C.3
Mulligan, P.4
Whetstine, J.R.5
Cole, P.A.6
Casero, R.A.7
Shi, Y.8
-
89
-
-
33847392500
-
Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression
-
Wissmann M et al (2007) Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression. Nat Cell Biol 9:347-353
-
(2007)
Nat Cell Biol
, vol.9
, pp. 347-353
-
-
Wissmann, M.1
-
90
-
-
24144462170
-
LSD1 demethylates repressive histone marks to promote androgen-receptor- dependent transcription
-
DOI 10.1038/nature04020, PII N04020
-
Metzger E et al (2005) LSD1 demethylates repressive histone marks to promote androgenreceptor- dependent transcription. Nature 437:436-439 (Pubitemid 41613508)
-
(2005)
Nature
, vol.437
, Issue.7057
, pp. 436-439
-
-
Metzger, E.1
Wissmann, M.2
Yin, N.3
Muller, J.M.4
Schneider, R.5
Peters, A.H.F.M.6
Gunther, T.7
Buettner, R.8
Schule, R.9
-
91
-
-
77950460256
-
Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4
-
Metzger E et al (2010) Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4. Nature 464:792-796
-
(2010)
Nature
, vol.464
, pp. 792-796
-
-
Metzger, E.1
-
92
-
-
35349006314
-
Histone lysine demethylases: Emerging roles in development, physiology and disease
-
DOI 10.1038/nrg2218, PII NRG2218
-
Shi Y (2007) Histone lysine demethylases: emerging roles in development, physiology and disease. Nat Rev Genet 8:829-833 (Pubitemid 47609092)
-
(2007)
Nature Reviews Genetics
, vol.8
, Issue.11
, pp. 829-833
-
-
Shi, Y.1
-
93
-
-
79956291600
-
Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis
-
Shi L et al (2011) Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis. Proc Natl Acad Sci USA 108:7541-7546
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 7541-7546
-
-
Shi, L.1
-
94
-
-
25144519737
-
An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation
-
DOI 10.1038/nature04021, PII N04021
-
Lee MG, Wynder C, Cooch N, Shiekhattar R (2005) An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation. Nature 437:432-435 (Pubitemid 41613507)
-
(2005)
Nature
, vol.437
, Issue.7057
, pp. 432-435
-
-
Lee, M.G.1
Wynder, C.2
Cooch, N.3
Shiekhattar, R.4
-
95
-
-
24944535335
-
Regulation of LSD1 histone demethylase activity by its associated factors
-
Shi YJ et al (2005) Regulation of LSD1 histone demethylase activity by its associated factors. Mol Cell 19:857-864
-
(2005)
Mol Cell
, vol.19
, pp. 857-864
-
-
Shi, Y.J.1
-
96
-
-
29244455626
-
Human histone demethylase LSD1 reads the histone code
-
DOI 10.1074/jbc.M509549200
-
Forneris F, Binda C, Vanoni MA, Battaglioli E, Mattevi A (2005) Human histone demethylase LSD1 reads the histone code. J Biol Chem 280:41360-41365 (Pubitemid 41832193)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.50
, pp. 41360-41365
-
-
Forneris, F.1
Binda, C.2
Vanoni, M.A.3
Battaglioli, E.4
Mattevi, A.5
-
98
-
-
80054761058
-
Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-speci fi c demethylase 1
-
Cai C et al (2011) Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-speci fi c demethylase 1. Cancer Cell 20:457-471
-
(2011)
Cancer Cell
, vol.20
, pp. 457-471
-
-
Cai, C.1
-
99
-
-
79952672993
-
Impulse control: Temporal dynamics in gene transcription
-
Yosef N, Regev A (2011) Impulse control: temporal dynamics in gene transcription. Cell 144:886-896
-
(2011)
Cell
, vol.144
, pp. 886-896
-
-
Yosef, N.1
Regev, A.2
-
100
-
-
57749195091
-
Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology
-
Alenghat T et al (2008) Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology. Nature 456(7224):997-1000
-
(2008)
Nature
, vol.456
, Issue.7224
, pp. 997-1000
-
-
Alenghat, T.1
-
101
-
-
61349117970
-
Genetics and epigenetics: Stability and plasticity during cellular differentiation
-
Mohn F, Schubeler D (2009) Genetics and epigenetics: stability and plasticity during cellular differentiation. Trends Genet 25:129-136
-
(2009)
Trends Genet
, vol.25
, pp. 129-136
-
-
Mohn, F.1
Schubeler, D.2
-
102
-
-
34548644772
-
The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
-
DOI 10.1016/j.cell.2007.08.019, PII S0092867407010823
-
De Santa F et al (2007) The histone H3 lysine-27 demethylase Jmjd3 links in fl ammation to inhibition of polycomb-mediated gene silencing. Cell 130:1083-1094 (Pubitemid 47410272)
-
(2007)
Cell
, vol.130
, Issue.6
, pp. 1083-1094
-
-
De Santa, F.1
Totaro, M.G.2
Prosperini, E.3
Notarbartolo, S.4
Testa, G.5
Natoli, G.6
-
103
-
-
37349068664
-
A map of human cancer signaling
-
Cui Q et al (2007) A map of human cancer signaling. Mol Syst Biol 3:152
-
(2007)
Mol Syst Biol
, vol.3
, pp. 152
-
-
Cui, Q.1
-
104
-
-
62449302589
-
Elongation dynamics shape bursty transcription and translation
-
Dobrzynski M, Bruggeman FJ (2009) Elongation dynamics shape bursty transcription and translation. Proc Natl Acad Sci USA 106(8):2583-2588
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.8
, pp. 2583-2588
-
-
Dobrzynski, M.1
Bruggeman, F.J.2
-
105
-
-
33847047461
-
Epigenetics: A landscape takes shape
-
DOI 10.1016/j.cell.2007.02.006, PII S0092867407001869
-
Goldberg AD, Allis CD, Bernstein E (2007) Epigenetics: a landscape takes shape. Cell 128:635-638 (Pubitemid 46273578)
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 635-638
-
-
Goldberg, A.D.1
Allis, C.D.2
Bernstein, E.3
-
106
-
-
77950443318
-
NER factors are recruited to active promoters and facilitate chromatin modi fi cation for transcription in the absence of exogenous genotoxic attack
-
Le May N et al (2010) NER factors are recruited to active promoters and facilitate chromatin modi fi cation for transcription in the absence of exogenous genotoxic attack. Mol Cell 38:54-66
-
(2010)
Mol Cell
, vol.38
, pp. 54-66
-
-
Le May, N.1
-
107
-
-
40449123137
-
Cyclical DNA methylation of a transcriptionally active promoter
-
DOI 10.1038/nature06544, PII NATURE06544
-
Metivier R et al (2008) Cyclical DNA methylation of a transcriptionally active promoter. Nature 452:45-50 (Pubitemid 351355084)
-
(2008)
Nature
, vol.452
, Issue.7183
, pp. 45-50
-
-
Metivier, R.1
Gallais, R.2
Tiffoche, C.3
Le Peron, C.4
Jurkowska, R.Z.5
Carmouche, R.P.6
Ibberson, D.7
Barath, P.8
Demay, F.9
Reid, G.10
Benes, V.11
Jeltsch, A.12
Gannon, F.13
Salbert, G.14
-
108
-
-
40449104358
-
Transient cyclical methylation of promoter DNA
-
DOI 10.1038/nature06640, PII NATURE06640
-
Kangaspeska S et al (2008) Transient cyclical methylation of promoter DNA. Nature 452:112-115 (Pubitemid 351355094)
-
(2008)
Nature
, vol.452
, Issue.7183
, pp. 112-115
-
-
Kangaspeska, S.1
Stride, B.2
Metivier, R.3
Polycarpou-Schwarz, M.4
Ibberson, D.5
Carmouche, R.P.6
Benes, V.7
Gannon, F.8
Reid, G.9
-
109
-
-
67650758019
-
Androgen receptor regulates a distinct transcription program in androgen- independent prostate cancer
-
Wang Q et al (2009) Androgen receptor regulates a distinct transcription program in androgen- independent prostate cancer. Cell 138:245-256
-
(2009)
Cell
, vol.138
, pp. 245-256
-
-
Wang, Q.1
-
110
-
-
23044499067
-
Distinct epigenetic changes in the stromal cells of breast cancers
-
DOI 10.1038/ng1596
-
Hu M et al (2005) Distinct epigenetic changes in the stromal cells of breast cancers. Nat Genet 37:899-905 (Pubitemid 41077119)
-
(2005)
Nature Genetics
, vol.37
, Issue.8
, pp. 899-905
-
-
Hu, M.1
Yao, J.2
Cai, L.3
Bachman, K.E.4
Van Den Brule, F.5
Velculescu, V.6
Polyak, K.7
-
111
-
-
33747859659
-
Stromal fibroblasts in cancer: A novel tumor-promoting cell type
-
Orimo A, Weinberg RA (2006) Stromal fi broblasts in cancer: a novel tumor-promoting cell type. Cell Cycle 5:1597-1601 (Pubitemid 44285243)
-
(2006)
Cell Cycle
, vol.5
, Issue.15
, pp. 1597-1601
-
-
Orimo, A.1
Weinberg, R.A.2
-
112
-
-
33646428091
-
Normal stem cells and cancer stem cells: The niche matters
-
Li L, Neaves WB (2006) Normal stem cells and cancer stem cells: the niche matters. Cancer Res 66:4553-4557
-
(2006)
Cancer Res
, vol.66
, pp. 4553-4557
-
-
Li, L.1
Neaves, W.B.2
-
113
-
-
29244469466
-
The epigenetic progenitor origin of human cancer
-
DOI 10.1038/nrg1748
-
Feinberg AP, Ohlsson R, Henikoff S (2006) The epigenetic progenitor origin of human cancer. Nat Rev Genet 7:21-33 (Pubitemid 41828945)
-
(2006)
Nature Reviews Genetics
, vol.7
, Issue.1
, pp. 21-33
-
-
Feinberg, A.P.1
Ohlsson, R.2
Henikoff, S.3
-
114
-
-
33748192942
-
The Myc oncoprotein as a therapeutic target for human cancer
-
DOI 10.1016/j.semcancer.2006.07.015, PII S1044579X06000666, 25 Years of ther c-Myc Oncogene
-
Vita M, Henriksson M (2006) The Myc oncoprotein as a therapeutic target for human cancer. Semin Cancer Biol 16:318-330 (Pubitemid 44311040)
-
(2006)
Seminars in Cancer Biology
, vol.16
, Issue.4
, pp. 318-330
-
-
Vita, M.1
Henriksson, M.2
-
115
-
-
0038185378
-
Genomic targets of the human c-Myc protein
-
DOI 10.1101/gad.1067003
-
Fernandez PC et al (2003) Genomic targets of the human c-Myc protein. Genes Dev 17:1115-1129 (Pubitemid 36534986)
-
(2003)
Genes and Development
, vol.17
, Issue.9
, pp. 1115-1129
-
-
Fernandez, P.C.1
Frank, S.R.2
Wang, L.3
Schroeder, M.4
Liu, S.5
Greene, J.6
Cocito, A.7
Amati, B.8
-
116
-
-
23144464363
-
Transcriptional regulation and transformation by Myc proteins
-
DOI 10.1038/nrm1703
-
Adhikary S, Eilers M (2005) Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 6:635-645 (Pubitemid 41081267)
-
(2005)
Nature Reviews Molecular Cell Biology
, vol.6
, Issue.8
, pp. 635-645
-
-
Adhikary, S.1
Eilers, M.2
-
117
-
-
33745737494
-
Myc-binding-site recognition in the human genome is determined by chromatin context
-
Guccione E et al (2006) Myc-binding-site recognition in the human genome is determined by chromatin context. Nat Cell Biol 8:764-770
-
(2006)
Nat Cell Biol
, vol.8
, pp. 764-770
-
-
Guccione, E.1
-
118
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein BE et al (2006) A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125:315-326
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
-
119
-
-
33947152396
-
The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth
-
DOI 10.1101/gad.1523007
-
Secombe J, Li L, Carlos L, Eisenman RN (2007) The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth. Genes Dev 21:537-551 (Pubitemid 46409469)
-
(2007)
Genes and Development
, vol.21
, Issue.5
, pp. 537-551
-
-
Secombe, J.1
Li, L.2
Carlos, L.3
Eisenman, R.N.4
-
120
-
-
34547687916
-
The function and regulation of the JARID1 family of histone H3 lysine 4 demethylases: The Myc connection
-
Secombe J, Eisenman RN (2007) The function and regulation of the JARID1 family of histone H3 lysine 4 demethylases: the Myc connection. Cell Cycle 6:1324-1328 (Pubitemid 47327965)
-
(2007)
Cell Cycle
, vol.6
, Issue.11
, pp. 1324-1328
-
-
Secombe, J.1
Eisenman, R.N.2
-
121
-
-
33847381108
-
Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer
-
DOI 10.1158/1535-7163.MCT-06-0659
-
Suzuki C et al (2007) Identi fi cation of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer. Mol Cancer Ther 6:542-551 (Pubitemid 46332456)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.2
, pp. 542-551
-
-
Suzuki, C.1
Takahashi, K.2
Hayama, S.3
Ishikawa, N.4
Kato, T.5
Ito, T.6
Tsuchiya, E.7
Nakamura, Y.8
Daigo, Y.9
-
122
-
-
77954378537
-
Accelerated expression of a Myc target gene Mina53 in aggressive hepatocellular carcinoma
-
Ogasawara S et al (2010) Accelerated expression of a Myc target gene Mina53 in aggressive hepatocellular carcinoma. Hepatol Res 40:330-336
-
(2010)
Hepatol Res
, vol.40
, pp. 330-336
-
-
Ogasawara, S.1
-
123
-
-
77449134200
-
Mina53, a novel c-Myc target gene, is frequently expressed in lung cancers and exerts oncogenic property in NIH/3T3 cells
-
Komiya K et al (2010) Mina53, a novel c-Myc target gene, is frequently expressed in lung cancers and exerts oncogenic property in NIH/3T3 cells. J Cancer Res Clin Oncol 136:465-473
-
(2010)
J Cancer Res Clin Oncol
, vol.136
, pp. 465-473
-
-
Komiya, K.1
-
124
-
-
39749124274
-
MYC in mammalian epidermis: How can an oncogene stimulate differentiation?
-
DOI 10.1038/nrc2328, PII NRC2328
-
Watt FM, Frye M, Benitah SA (2008) MYC in mammalian epidermis: how can an oncogene stimulate differentiation? Nat Rev Cancer 8:234-242 (Pubitemid 351301841)
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.3
, pp. 234-242
-
-
Watt, F.M.1
Frye, M.2
Benitah, S.A.3
-
125
-
-
1042278171
-
Synergistic effects of coactivators GRIP1 and β-catenin on gene activation. Cross-talk between androgen receptor and Wnt signaling pathways
-
DOI 10.1074/jbc.M311374200
-
Li H, Kim JH, Koh SS, Stallcup MR (2004) Synergistic effects of coactivators GRIP1 and beta-catenin on gene activation: cross-talk between androgen receptor and Wnt signaling pathways. J Biol Chem 279:4212-4220 (Pubitemid 38199008)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.6
, pp. 4212-4220
-
-
Li, H.1
Kim, J.H.2
Koh, S.S.3
Stallcup, M.R.4
-
126
-
-
33745052416
-
Complex regulation of human androgen receptor expression by Wnt signaling in prostate cancer cells
-
DOI 10.1038/sj.onc.1209366, PII 1209366
-
Yang X et al (2006) Complex regulation of human androgen receptor expression by Wnt signaling in prostate cancer cells. Oncogene 25(24):3436-3444 (Pubitemid 43877046)
-
(2006)
Oncogene
, vol.25
, Issue.24
, pp. 3436-3444
-
-
Yang, X.1
Chen, M.-W.2
Terry, S.3
Vacherot, F.4
Bemis, D.L.5
Capodice, J.6
Kitajewski, J.7
De La Taille, A.8
Benson, M.C.9
Guo, Y.10
Buttyan, R.11
-
127
-
-
0030737494
-
3 analogue involves the induction of p21(waf1) p27(kip1) and E-cadherin
-
Campbell MJ, Elstner E, Holden S, Uskokovic M, Koef fl er HP (1997) Inhibition of proliferation of prostate cancer cells by a 19-nor-hexa fl uoride vitamin D3 analogue involves the induction of p21waf1, p27kip1 and E-cadherin. J Mol Endocrinol 19:15-27 (Pubitemid 27345239)
-
(1997)
Journal of Molecular Endocrinology
, vol.19
, Issue.1
, pp. 15-27
-
-
Campbell, M.J.1
Elstner, E.2
Holden, S.3
Uskokovic, M.4
Koeffler, H.P.5
-
128
-
-
33845979155
-
The insulin-like growth factor-binding protein 1 gene is a primary target of peroxisome proliferator-activated receptors
-
DOI 10.1074/jbc.M605623200
-
Degenhardt T, Matilainen M, Herzig KH, Dunlop TW, Carlberg C (2006) The insulin-like growth factor binding protein 1 gene is a primary target of peroxisome proliferator-activated receptors. J Biol Chem 281(51):39607-39619 (Pubitemid 46041920)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.51
, pp. 39607-39619
-
-
Degenhardt, T.1
Matilainen, M.2
Herzig, K.-H.3
Dunlop, T.W.4
Carlberg, C.5
-
129
-
-
4644309396
-
3 receptor signalling in prostate cancer cells
-
DOI 10.1038/sj.onc.1207772
-
Khanim FL et al (2004) Altered SMRT levels disrupt vitamin D(3) receptor signalling in prostate cancer cells. Oncogene 23:6712-6725 (Pubitemid 39280003)
-
(2004)
Oncogene
, vol.23
, Issue.40
, pp. 6712-6725
-
-
Khanim, F.L.1
Gommersall, L.M.2
Wood, V.H.J.3
Smith, K.L.4
Montalvo, L.5
O'Neill, L.P.6
Xu, Y.7
Peehl, D.M.8
Stewart, P.M.9
Turner, B.M.10
Campbell, M.J.11
-
130
-
-
0032146179
-
3 analogs: A unique class of potent inhibitors of proliferation of prostate, breast, and hematopoietic cancer cells
-
Kubota T et al (1998) 19-nor-26,27-bishomo-vitamin D3 analogs: a unique class of potent inhibitors of proliferation of prostate, breast, and hematopoietic cancer cells. Cancer Res 58:3370-3375 (Pubitemid 28371078)
-
(1998)
Cancer Research
, vol.58
, Issue.15
, pp. 3370-3375
-
-
Kubota, T.1
Koshizuka, K.2
Koike, M.3
Uskokovic, M.4
Miyoshi, I.5
Koeffler, H.P.6
-
131
-
-
0030065422
-
3 leads to the induced differentiation of the myelomonocytic cell line U937
-
Liu M, Lee MH, Cohen M, Bommakanti M, Freedman LP (1996) Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937. Genes Dev 10:142-153 (Pubitemid 26049905)
-
(1996)
Genes and Development
, vol.10
, Issue.2
, pp. 142-153
-
-
Liu, M.1
Lee, M.-H.2
Cohen, M.3
Bommakanti, M.4
Freedman, L.P.5
-
132
-
-
4644229397
-
The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer
-
DOI 10.1038/nm1095
-
Palmer HG et al (2004) The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer. Nat Med 10:917-919 (Pubitemid 39273731)
-
(2004)
Nature Medicine
, vol.10
, Issue.9
, pp. 917-919
-
-
Palmer, H.G.1
Larriba, M.J.2
Garcia, J.M.3
Ordonez-Moran, P.4
Pena, C.5
Peiro, S.6
Puig, I.7
Rodriguez, R.8
De La Fuente, R.9
Bernad, A.10
Pollan, M.11
Bonilla, F.12
Gamallo, C.13
Garcia De Herreros, A.14
Munoz, A.15
-
133
-
-
32644451972
-
3 receptor
-
DOI 10.1093/nar/gkj460
-
Saramaki A, Banwell CM, Campbell MJ, Carlberg C (2006) Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor. Nucleic Acids Res 34:543-554 (Pubitemid 43240242)
-
(2006)
Nucleic Acids Research
, vol.34
, Issue.2
, pp. 543-554
-
-
Saramaki, A.1
Banwell, C.M.2
Campbell, M.J.3
Carlberg, C.4
-
134
-
-
42149112201
-
The vitamin D receptor in cancer
-
DOI 10.1017/S0029665108006964, PII S0029665108006964
-
Thorne J, Campbell MJ (2008) The vitamin D receptor in cancer. Proc Nutr Soc 67:115-127 (Pubitemid 351543394)
-
(2008)
Proceedings of the Nutrition Society
, vol.67
, Issue.2
, pp. 115-127
-
-
Thorne, J.1
Campbell, M.J.2
-
135
-
-
33744905821
-
Evolution of the androgen receptor pathway during progression of prostate cancer
-
DOI 10.1158/0008-5472.CAN-05-3082
-
Hendriksen PJ et al (2006) Evolution of the androgen receptor pathway during progression of prostate cancer. Cancer Res 66:5012-5020 (Pubitemid 43844921)
-
(2006)
Cancer Research
, vol.66
, Issue.10
, pp. 5012-5020
-
-
Hendriksen, P.J.M.1
Dits, N.F.J.2
Kokame, K.3
Veldhoven, A.4
Van Weerden, W.M.5
Bangma, C.H.6
Trapman, J.7
Jenster, G.8
-
136
-
-
11144355585
-
ART-27, An androgen receptor coactivator regulated in prostate development and cancer
-
DOI 10.1074/jbc.M306576200
-
Taneja SS et al (2004) ART-27, an androgen receptor coactivator regulated in prostate development and cancer. J Biol Chem 279:13944-13952 (Pubitemid 38468927)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.14
, pp. 13944-13952
-
-
Taneja, S.S.1
Ha, S.2
Swenson, N.K.3
Torra, I.P.4
Rome, S.5
Walden, P.D.6
Huang, H.Y.7
Shapiro, E.8
Garabedian, M.J.9
Logan, S.K.10
-
137
-
-
84856008906
-
Differential oestrogen receptor binding is associated with clinical outcome in breast cancer
-
Ross-Innes CS et al (2012) Differential oestrogen receptor binding is associated with clinical outcome in breast cancer. Nature 481(7381):389-393
-
(2012)
Nature
, vol.481
, Issue.7381
, pp. 389-393
-
-
Ross-Innes, C.S.1
-
138
-
-
79958066795
-
Methylation speci fi es distinct estrogen-induced binding site repertoires of CBP to chromatin
-
Ceschin DG et al (2011) Methylation speci fi es distinct estrogen-induced binding site repertoires of CBP to chromatin. Genes Dev 25:1132-1146
-
(2011)
Genes Dev
, vol.25
, pp. 1132-1146
-
-
Ceschin, D.G.1
-
139
-
-
66549085342
-
ChIP-Seq of ERalpha and RNA polymerase II de fi nes genes differentially responding to ligands
-
Welboren WJ et al (2009) ChIP-Seq of ERalpha and RNA polymerase II de fi nes genes differentially responding to ligands. EMBO J 28:1418-1428
-
(2009)
EMBO J
, vol.28
, pp. 1418-1428
-
-
Welboren, W.J.1
-
140
-
-
0035810045
-
3 and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A
-
DOI 10.1038/sj.onc.1204269
-
Rashid SF et al (2001) Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexa fl uoride analogs in combination with either sodium butyrate or trichostatin A. Oncogene 20:1860-1872 (Pubitemid 32458696)
-
(2001)
Oncogene
, vol.20
, Issue.15
, pp. 1860-1872
-
-
Rashid, S.F.1
Moore, J.S.2
Walker, E.3
Driver, P.M.4
Engel, J.5
Edwards, C.E.6
Brown, G.7
Uskokovic, M.R.8
Campbell, M.J.9
-
141
-
-
62349138999
-
Elevated NCOR1 disrupts a network of dietary-sensing nuclear receptors in bladder cancer cells
-
Abedin SA et al (2009) Elevated NCOR1 disrupts a network of dietary-sensing nuclear receptors in bladder cancer cells. Carcinogenesis 30(3):449-456
-
(2009)
Carcinogenesis
, vol.30
, Issue.3
, pp. 449-456
-
-
Abedin, S.A.1
-
143
-
-
33646239624
-
Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells
-
Banwell CM et al (2006) Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells. Clin Cancer Res 12:2004-2013
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2004-2013
-
-
Banwell, C.M.1
-
144
-
-
34548684576
-
3 responsiveness
-
DOI 10.1158/1541-7786.MCR-06-0318
-
Ting HJ, Bao BY, Reeder JE, Messing EM, Lee YF (2007) Increased expression of corepressors in aggressive androgen-independent prostate cancer cells results in loss of 1alpha,25- dihydroxyvitamin D3 responsiveness. Mol Cancer Res 5:967-980 (Pubitemid 47416673)
-
(2007)
Molecular Cancer Research
, vol.5
, Issue.9
, pp. 967-980
-
-
Ting, H.-J.1
Bao, B.-Y.2
Reeder, J.3
Messing, E.M.4
Lee, Y.-F.5
-
145
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
DOI 10.1126/science.1117679
-
Tomlins SA et al (2005) Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310:644-648 (Pubitemid 41528150)
-
(2005)
Science
, vol.310
, Issue.5748
, pp. 644-648
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
Dhanasekaran, S.M.4
Mehra, R.5
Sun, X.-W.6
Varambally, S.7
Cao, X.8
Tchinda, J.9
Kuefer, R.10
Lee, C.11
Montie, J.E.12
Shah, R.B.13
Pienta, K.J.14
Rubin, M.A.15
Chinnaiyan, A.M.16
-
146
-
-
9444234519
-
Overlapping transcriptional programs regulated by the nuclear receptors peroxisome proliferator-activated receptor α, retinoid X receptor, and liver X receptor in mouse liver
-
DOI 10.1124/mol.104.005496
-
Anderson SP et al (2004) Overlapping transcriptional programs regulated by the nuclear receptors peroxisome proliferator-activated receptor {alpha}, retinoid X receptor and liver X receptor in mouse liver. Mol Pharmacol 66(6):1440-1452 (Pubitemid 39564771)
-
(2004)
Molecular Pharmacology
, vol.66
, Issue.6
, pp. 1440-1452
-
-
Anderson, S.P.1
Dunn, C.2
Laughter, A.3
Yoon, L.4
Swanson, C.5
Stulnig, T.M.6
Steffensen, K.R.7
Chandraratna, R.A.S.8
Gustafsson, J.-A.9
Corton, J.C.10
-
147
-
-
33747154772
-
Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network
-
DOI 10.1016/j.cell.2006.06.049, PII S0092867406009779
-
Bookout AL et al (2006) Anatomical pro fi ling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell 126:789-799 (Pubitemid 44233630)
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 789-799
-
-
Bookout, A.L.1
Jeong, Y.2
Downes, M.3
Yu, R.T.4
Evans, R.M.5
Mangelsdorf, D.J.6
-
148
-
-
9944265844
-
Regulatory network of lipid-sensing nuclear receptors: Roles for CAR, PXR, LXR, and FXR
-
DOI 10.1016/j.abb.2004.08.030, PII S0003986104004953
-
Handschin C, Meyer UA (2005) Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR. Arch Biochem Biophys 433:387-396 (Pubitemid 39592793)
-
(2005)
Archives of Biochemistry and Biophysics
, vol.433
, Issue.2
, pp. 387-396
-
-
Handschin, C.1
Meyer, U.A.2
-
149
-
-
63449103705
-
Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis
-
Xia X et al (2009) Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis. Proc Natl Acad Sci USA 106:4260-4265
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 4260-4265
-
-
Xia, X.1
-
150
-
-
77958111633
-
The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation
-
Malik S, Roeder RG (2010) The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation. Nat Rev Genet 11:761-772
-
(2010)
Nat Rev Genet
, vol.11
, pp. 761-772
-
-
Malik, S.1
Roeder, R.G.2
-
151
-
-
69249110003
-
Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family
-
Xu J, Wu RC, O'Malley BW (2009) Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family. Nat Rev Cancer 9:615-630
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 615-630
-
-
Xu, J.1
Wu, R.C.2
O'Malley, B.W.3
-
154
-
-
77951241767
-
Transcription factor co-repressors in cancer biology: Roles and targeting
-
Battaglia S, Maguire O, Campbell MJ (2010) Transcription factor co-repressors in cancer biology: roles and targeting. Int J Cancer 126:2511-2519
-
(2010)
Int J Cancer
, vol.126
, pp. 2511-2519
-
-
Battaglia, S.1
Maguire, O.2
Campbell, M.J.3
-
155
-
-
0030797902
-
AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer
-
DOI 10.1126/science.277.5328.965
-
Anzick SL et al (1997) AIB1, a steroid receptor coactivator ampli fi ed in breast and ovarian cancer. Science 277:965-968 (Pubitemid 27366683)
-
(1997)
Science
, vol.277
, Issue.5328
, pp. 965-968
-
-
Anzick, S.L.1
Kononen, J.2
Walker, R.L.3
Azorsa, D.O.4
Tanner, M.M.5
Guan, X.-Y.6
Sauter, G.7
Kallioniemi, O.-P.8
Trent, J.M.9
Meltzer, P.S.10
-
156
-
-
0037203771
-
Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators
-
DOI 10.1038/415549a
-
Demarest SJ et al (2002) Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators. Nature 415:549-553 (Pubitemid 34130612)
-
(2002)
Nature
, vol.415
, Issue.6871
, pp. 549-553
-
-
Demarest, S.J.1
Martinez-Yamout, M.2
Chung, J.3
Chen, H.4
Xu, W.5
Jane Dyson, H.6
Evans, R.M.7
Wright, P.E.8
-
157
-
-
0038679380
-
Elevated expression levels of NCOA3, TOP1, and TFAP2C in breast tumors as predictors of poor prognosis
-
DOI 10.1002/cncr.11482
-
Zhao C et al (2003) Elevated expression levels of NCOA3, TOP1, and TFAP2C in breast tumors as predictors of poor prognosis. Cancer 98:18-23 (Pubitemid 36741120)
-
(2003)
Cancer
, vol.98
, Issue.1
, pp. 18-23
-
-
Zhao, C.1
Yasui, K.2
Lee, C.J.3
Kurioka, H.4
Hosokawa, Y.5
Oka, T.6
Inazawa, J.7
-
158
-
-
33646145721
-
Circadian regulator CLOCK is a histone acetyltransferase
-
Doi M, Hirayama J, Sassone-Corsi P (2006) Circadian regulator CLOCK is a histone acetyltransferase. Cell 125:497-508
-
(2006)
Cell
, vol.125
, pp. 497-508
-
-
Doi, M.1
Hirayama, J.2
Sassone-Corsi, P.3
-
159
-
-
40749147216
-
NCOA3, a new fusion partner for MOZ/MYST3 in M5 acute myeloid leukemia [13]
-
DOI 10.1038/sj.leu.2404930, PII 2404930
-
Esteyries S et al (2008) NCOA3, a new fusion partner for MOZ/MYST3 in M5 acute myeloid leukemia. Leukemia 22:663-665 (Pubitemid 351386746)
-
(2008)
Leukemia
, vol.22
, Issue.3
, pp. 663-665
-
-
Esteyries, S.1
Perot, C.2
Adelaide, J.3
Imbert, M.4
Lagarde, A.5
Pautas, C.6
Olschwang, S.7
Birnbaum, D.8
Chaffanet, M.9
Mozziconacci, M.-J.10
-
160
-
-
0029132202
-
Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor
-
Horlein AJ et al (1995) Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor. Nature 377:397-404
-
(1995)
Nature
, vol.377
, pp. 397-404
-
-
Horlein, A.J.1
-
161
-
-
0029097233
-
A transcriptional co-repressor that interacts with nuclear hormone receptors
-
Chen JD, Evans RM (1995) A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377:454-457
-
(1995)
Nature
, vol.377
, pp. 454-457
-
-
Chen, J.D.1
Evans, R.M.2
-
162
-
-
0034663815
-
Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3
-
Li J et al (2000) Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3. EMBO J 19:4342-4350 (Pubitemid 30623745)
-
(2000)
EMBO Journal
, vol.19
, Issue.16
, pp. 4342-4350
-
-
Li, J.1
Wang, J.2
Wang, J.3
Nawaz, Z.4
Liu, J.M.5
Qin, J.6
Wong, J.7
-
163
-
-
45249121924
-
The nuclear receptor corepressors NCoR and SMRT decrease PPARgamma transcriptional activity and repress 3T3-L1 adipogenesis
-
Yu C et al (2005) The nuclear receptor corepressors NCoR and SMRT decrease PPARgamma transcriptional activity and repress 3T3-L1 adipogenesis. J. Biol, Chem
-
(2005)
J. Biol, Chem
-
-
Yu, C.1
-
164
-
-
41149118120
-
Cooperative regulation in development by SMRT and FOXP1
-
DOI 10.1101/gad.1637108
-
Jepsen K, Gleiberman AS, Shi C, Simon DI, Rosenfeld MG (2008) Cooperative regulation in development by SMRT and FOXP1. Genes Dev 22:740-745 (Pubitemid 351439105)
-
(2008)
Genes and Development
, vol.22
, Issue.6
, pp. 740-745
-
-
Jepsen, K.1
Gleiberman, A.S.2
Shi, C.3
Simon, D.I.4
Rosenfeld, M.G.5
-
166
-
-
79953871100
-
Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor
-
Surjit M et al (2011) Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor. Cell 145:224-241
-
(2011)
Cell
, vol.145
, pp. 224-241
-
-
Surjit, M.1
-
167
-
-
82255185583
-
Nuclear hormone 1{alpha},25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy
-
Heikkinen S et al (2011) Nuclear hormone 1{alpha},25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy. Nucleic Acids Res 39(21):9181-9193
-
(2011)
Nucleic Acids Res
, vol.39
, Issue.21
, pp. 9181-9193
-
-
Heikkinen, S.1
-
168
-
-
78149356747
-
Pro fi ling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia
-
Muller-Tidow C et al (2010) Pro fi ling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia. Blood 116:3564-3571
-
(2010)
Blood
, vol.116
, pp. 3564-3571
-
-
Muller-Tidow, C.1
-
169
-
-
41949133411
-
Chromatin modi fi cations induced by PML-RARalpha repress critical targets in leukemogenesis as analyzed by ChIP-Chip
-
Hoemme C et al (2008) Chromatin modi fi cations induced by PML-RARalpha repress critical targets in leukemogenesis as analyzed by ChIP-Chip. Blood 111:2887-2895
-
(2008)
Blood
, vol.111
, pp. 2887-2895
-
-
Hoemme, C.1
-
170
-
-
0033638969
-
Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation
-
Minucci S et al (2000) Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation. Mol Cell 5:811-820
-
(2000)
Mol Cell
, vol.5
, pp. 811-820
-
-
Minucci, S.1
-
171
-
-
0037388540
-
Expression analysis of estrogen receptor α coregulators in breast carcinoma: Evidence that NCOR1 expression is predictive of the response to tamoxifen
-
Girault I et al (2003) Expression analysis of estrogen receptor alpha coregulators in breast carcinoma: evidence that NCOR1 expression is predictive of the response to tamoxifen. Clin Cancer Res 9:1259-1266 (Pubitemid 36418375)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.4
, pp. 1259-1266
-
-
Girault, I.1
Lerebours, F.2
Amarir, S.3
Tozlu, S.4
Tubiana-Hulin, M.5
Lidereau, R.6
Bieche, I.7
-
172
-
-
33646512652
-
NCOR1 mRNA is an independent prognostic factor for breast cancer
-
Zhang Z et al (2005) NCOR1 mRNA is an independent prognostic factor for breast cancer. Cancer Lett 237(1):123-129
-
(2005)
Cancer Lett
, vol.237
, Issue.1
, pp. 123-129
-
-
Zhang, Z.1
-
173
-
-
58849132061
-
Involvement of SMRT corepressor in transcriptional repression by the vitamin D receptor
-
Kim JY, Son YL, Lee YC (2009) Involvement of SMRT corepressor in transcriptional repression by the vitamin D receptor. Mol Endocrinol 23:251-264
-
(2009)
Mol Endocrinol
, vol.23
, pp. 251-264
-
-
Kim, J.Y.1
Son, Y.L.2
Lee, Y.C.3
-
174
-
-
0036554932
-
Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-γ and inhibitors of histone deacetylase in adenocarcinoma of the lung
-
Chang TH, Szabo E (2002) Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-gamma and inhibitors of histone deacetylase in adenocarcinoma of the lung. Clin Cancer Res 8:1206-1212 (Pubitemid 35177376)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.4
, pp. 1206-1212
-
-
Chang, T.-H.1
Szabo, E.2
-
175
-
-
77956296891
-
Elevated NCOR1 disrupts PPAR signaling in prostate cancer and forms a targetable epigenetic lesion
-
Battaglia S et al (2010) Elevated NCOR1 disrupts PPAR signaling in prostate cancer and forms a targetable epigenetic lesion. Carcinogenesis 31(9):1650-1660
-
(2010)
Carcinogenesis
, vol.31
, Issue.9
, pp. 1650-1660
-
-
Battaglia, S.1
-
176
-
-
78650994865
-
The three-dimensional folding of the alpha-globin gene domain reveals formation of chromatin globules
-
Bau D et al (2011) The three-dimensional folding of the alpha-globin gene domain reveals formation of chromatin globules. Nat Struct Mol Biol 18:107-114
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 107-114
-
-
Bau, D.1
-
177
-
-
33645887244
-
Chromatin looping and the probability of transcription
-
Li Q, Barkess G, Qian H (2006) Chromatin looping and the probability of transcription. Trends Genet 22:197-202
-
(2006)
Trends Genet
, vol.22
, pp. 197-202
-
-
Li, Q.1
Barkess, G.2
Qian, H.3
-
178
-
-
47649111278
-
RNA polymerase II activity is located on the surface of protein-rich transcription factories
-
DOI 10.1242/jcs.027250
-
Eskiw CH, Rapp A, Carter DR, Cook PR (2008) RNA polymerase II activity is located on the surface of protein-rich transcription factories. J Cell Sci 121:1999-2007 (Pubitemid 352015197)
-
(2008)
Journal of Cell Science
, vol.121
, Issue.12
, pp. 1999-2007
-
-
Eskiw, C.H.1
Rapp, A.2
Carter, D.R.F.3
Cook, P.R.4
-
179
-
-
38149133051
-
Transcription factories are nuclear subcompartments that remain in the absence of transcription
-
Mitchell JA, Fraser P (2008) Transcription factories are nuclear subcompartments that remain in the absence of transcription. Genes Dev 22:20-25
-
(2008)
Genes Dev
, vol.22
, pp. 20-25
-
-
Mitchell, J.A.1
Fraser, P.2
-
180
-
-
58049208232
-
Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules
-
Hu Q et al (2008) Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules. Proc Natl Acad Sci USA 105:19199-19204
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19199-19204
-
-
Hu, Q.1
-
181
-
-
0141638426
-
N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso
-
DOI 10.1016/j.molcel.2003.08.008
-
Yoon HG, Chan DW, Reynolds AB, Qin J, Wong J (2003) N-CoR mediates DNA methylationdependent repression through a methyl CpG binding protein Kaiso. Mol Cell 12:723-734 (Pubitemid 37222492)
-
(2003)
Molecular Cell
, vol.12
, Issue.3
, pp. 723-734
-
-
Yoon, H.-G.1
Chan, D.W.2
Reynolds, A.B.3
Qin, J.4
Wong, J.5
-
182
-
-
12144289173
-
Hypermethylation of CpG Islands in primary and metastatic human prostate cancer
-
DOI 10.1158/0008-5472.CAN-03-3972
-
Yegnasubramanian S et al (2004) Hypermethylation of CpG islands in primary and metastatic human prostate cancer. Cancer Res 64:1975-1986 (Pubitemid 38339443)
-
(2004)
Cancer Research
, vol.64
, Issue.6
, pp. 1975-1986
-
-
Yegnasubramanian, S.1
Kowalski, J.2
Gonzalgo, M.L.3
Zahurak, M.4
Piantadosi, S.5
Walsh, P.C.6
Bova, G.S.7
De Marzo, A.M.8
Isaacs, W.B.9
Nelson, W.G.10
-
183
-
-
13944249886
-
Deletion, methylation, and expression of the NKX3.1 suppressor gene in primary human prostate cancer
-
DOI 10.1158/0008-5472.CAN-04-2688
-
Asatiani E et al (2005) Deletion, methylation, and expression of the NKX3.1 suppressor gene in primary human prostate cancer. Cancer Res 65:1164-1173 (Pubitemid 40270140)
-
(2005)
Cancer Research
, vol.65
, Issue.4
, pp. 1164-1173
-
-
Asatiani, E.1
Huang, W.-X.2
Wang, A.3
Ortner, E.R.4
Cavalli, L.R.5
Haddad, B.R.6
Gelmann, E.P.7
-
184
-
-
0037591867
-
Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression
-
DOI 10.1074/jbc.M302283200
-
Fujita N et al (2003) Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression. J Biol Chem 278:24132-24138 (Pubitemid 36830249)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.26
, pp. 24132-24138
-
-
Fujita, N.1
Watanabe, S.2
Ichimura, T.3
Tsuruzoe, S.4
Shinkai, Y.5
Tachibana, M.6
Chiba, T.7
Nakao, M.8
-
185
-
-
33751209468
-
Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication
-
Esteve PO et al (2006) Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication. Genes Dev 20:3089-3103
-
(2006)
Genes Dev
, vol.20
, pp. 3089-3103
-
-
Esteve, P.O.1
-
186
-
-
77950678085
-
Coordinated chromatin control: Structural and functional linkage of DNA and histone methylation
-
Cheng X, Blumenthal RM (2010) Coordinated chromatin control: structural and functional linkage of DNA and histone methylation. Biochemistry 49:2999-3008
-
(2010)
Biochemistry
, vol.49
, pp. 2999-3008
-
-
Cheng, X.1
Blumenthal, R.M.2
-
187
-
-
1242271994
-
HP1 is essential for DNA methylation in neurospora
-
DOI 10.1016/S1097-2765(04)00024-3
-
Freitag M, Hickey PC, Khlafallah TK, Read ND, Selker EU (2004) HP1 is essential for DNA methylation in Neurospora. Mol Cell 13:427-434 (Pubitemid 38229814)
-
(2004)
Molecular Cell
, vol.13
, Issue.3
, pp. 427-434
-
-
Freitag, M.1
Hickey, P.C.2
Khlafallah, T.K.3
Read, N.D.4
Selker, E.U.5
-
188
-
-
34250305146
-
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
-
DOI 10.1038/nature05874, PII NATURE05874
-
Birney E et al (2007) Identi fi cation and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 447:799-816 (Pubitemid 46920138)
-
(2007)
Nature
, vol.447
, Issue.7146
, pp. 799-816
-
-
Birney, E.1
Stamatoyannopoulos, J.A.2
Dutta, A.3
Guigo, R.4
Gingeras, T.R.5
Margulies, E.H.6
Weng, Z.7
Snyder, M.8
Dermitzakis, E.T.9
Thurman, R.E.10
Kuehn, M.S.11
Taylor, C.M.12
Neph, S.13
Koch, C.M.14
Asthana, S.15
Malhotra, A.16
Adzhubei, I.17
Greenbaum, J.A.18
Andrews, R.M.19
Flicek, P.20
Boyle, P.J.21
Cao, H.22
Carter, N.P.23
Clelland, G.K.24
Davis, S.25
Day, N.26
Dhami, P.27
Dillon, S.C.28
Dorschner, M.O.29
Fiegler, H.30
Giresi, P.G.31
Goldy, J.32
Hawrylycz, M.33
Haydock, A.34
Humbert, R.35
James, K.D.36
Johnson, B.E.37
Johnson, E.M.38
Frum, T.T.39
Rosenzweig, E.R.40
Karnani, N.41
Lee, K.42
Lefebvre, G.C.43
Navas, P.A.44
Neri, F.45
Parker, S.C.J.46
Sabo, P.J.47
Sandstrom, R.48
Shafer, A.49
Vetrie, D.50
Weaver, M.51
Wilcox, S.52
Yu, M.53
Collins, F.S.54
Dekker, J.55
Lieb, J.D.56
Tullius, T.D.57
Crawford, G.E.58
Sunyaev, S.59
Noble, W.S.60
Dunham, I.61
Denoeud, F.62
Reymond, A.63
Kapranov, P.64
Rozowsky, J.65
Zheng, D.66
Castelo, R.67
Frankish, A.68
Harrow, J.69
Ghosh, S.70
Sandelin, A.71
Hofacker, I.L.72
Baertsch, R.73
Keefe, D.74
Dike, S.75
Cheng, J.76
Hirsch, H.A.77
Sekinger, E.A.78
Lagarde, J.79
Abril, J.F.80
Shahab, A.81
Flamm, C.82
Fried, C.83
Hackermuller, J.84
Hertel, J.85
Lindemeyer, M.86
Missal, K.87
Tanzer, A.88
Washietl, S.89
Korbel, J.90
Emanuelsson, O.91
Pedersen, J.S.92
Holroyd, N.93
Taylor, R.94
Swarbreck, D.95
more..
-
189
-
-
62449197931
-
Lysine-speci fi c demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: Implications for therapy
-
Schulte JH et al (2009) Lysine-speci fi c demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy. Cancer Res 69:2065-2071
-
(2009)
Cancer Res
, vol.69
, pp. 2065-2071
-
-
Schulte, J.H.1
-
190
-
-
64049097640
-
The promises and pitfalls of epigenetic therapies in solid tumours
-
Graham JS, Kaye SB, Brown R (2009) The promises and pitfalls of epigenetic therapies in solid tumours. Eur J Cancer 45:1129-1136
-
(2009)
Eur J Cancer
, vol.45
, pp. 1129-1136
-
-
Graham, J.S.1
Kaye, S.B.2
Brown, R.3
|