Effects of five days of bed rest with and without exercise countermeasure on postural stability and gait

Journal of Musculoskeletal Neuronal Interactions

Volumn 14, Issue 3, 2014, Pages 359-366

  Mulder, E ^a   Linnarsson, D ^b   Paloski, W H ^c   Rittweger, J ^a   Wuyts, F L ^d   Zange, J ^a   Clement G ^e,f  

^a GERMAN AEROSPACE CENTER DLR   (Germany)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF HOUSTON   (United States)

^d UNIVERSITY OF ANTWERP   (Belgium)

^e INTERNATIONAL SPACE UNIVERSITY   (France)

^f LYON NEUROSCIENCE RESEARCH CENTER   (France)

Author keywords

Artificial gravity; Balance; Bed rest; Centrifugation; Gait; Posturography

Indexed keywords

ADULT; ARTICLE; BALANCE DISORDER; BED REST; BODY EQUILIBRIUM; BODY POSTURE; CLINICAL EFFECTIVENESS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; EXERCISE; FALL RISK ASSESSMENT; GAIT; HEAD MOVEMENT; HEEL RAISING; HOPPING EXERCISE; HUMAN; HUMAN EXPERIMENT; LOCOMOTION; MALE; NORMAL HUMAN; OUTCOME ASSESSMENT; PROPRIOCEPTION; SQUATTING; STANDING; TASK PERFORMANCE; WEIGHTLESSNESS; ADVERSE EFFECTS; DIZZINESS; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADULT; BED REST; DIZZINESS; EXERCISE; GAIT; HUMANS; LOCOMOTION; MALE; POSTURAL BALANCE; POSTURE; PROPRIOCEPTION; WEIGHTLESSNESS COUNTERMEASURES; WEIGHTLESSNESS SIMULATION;

EID: 84907063473     PISSN: 11087161     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Pavy-LeTraon A, Heer M, Narici MV, Rittweger J, Vernikos J. From space to earth: Advances in human physiology from 20 years of bed rest studies (1986-2006). Eur J Appl Physiol 2007;101:143-194.
2. Buckey JC, Lane LD, Levine BD, Watenpaugh DE, Wright SJ, Moore WE, Gaffney FA, Blumqvist CG. Orthostatic intolerance after spaceflight. J Appl Physiol 1996;81:7-18.
3. Vil-Viliams IF. Principle approaches to selection of the short-arm centrifuge regimens for extended space flight. Acta Astronaut 1994;33:221-229.
4. Young LR. Artificial gravity considerations for a Mars exploration mission. Ann NY Acad Sci 1999;28:367-378.
5. Clément G, Pavy-Le Traon A. Centrifugation as a countermeasure during actual and simulated microgravity: a review. Eur J Appl Physiol 2004;92:235-248.
6. Vernikos J, Ludwig DA, Ertl AC, Wade CE, Keil L, O’Hara D. Effect of standing or walking on physiological changes induced by head down bed rest: Implications for spaceflight. Aviat Space Environ Med 1996;67:1069-1079.
7. Evans JM, Stenger MB, Moore FB, Hinghoffer-Szalkay H, Rossler A, Patwardhan AR, et al. Centrifuge training increases presyncopal orthostatic tolerance in ambulatory men. Aviat Space Environ Med 2004;75:850-858.
8. Greenleaf JE, Gundo DP, Watenpaugh DE, Mulenburg GM, Marchman N, Looft-Wilson R, et al. Cycle-powered short radius (1.9 m) centrifuge: exercise vs. passive acceleration. J Gravit Physiol 1996;3:61-62.
9. Akima H, Katayama K, Sato K, Ishida K, Masuda K, Takada H, et al. Intensive cycle training with artificial gravity maintains muscle size during bed rest. Aviat Space Environ Med 2005;76:923-929.
10. Iwasaki K, Shiozawa T, Kamiya A, Michikami D, Hirayanagi K, Yajima K, et al. Hypergravity exercise against bed rest induced changes in cardiac autonomic control. Eur J Appl Physiol 2005;94:285-291.
11. Iwase S. Effectiveness of centrifuge-induced artificial gravity with ergometric exercise as a countermeasure dur ing simulated microgravity exposure in humans. Acta Astronaut 2005;57:75-80.
12. Arya M, Paloski W., Young LR. Centrifugation protocol for the NASA artificial gravity-bed rest pilot study. J Gravit Physiol 2007;14:5-8.
13. Warren LE, Reinertson R, Camacho ME, Paloski WH. Implementation of the NASA artificial gravity bed rest pilot study. J Gravit Physiol 2007;14:1-4.
14. Symons TB, Sheffield-Moore M, Chinkes DL, Ferrando AA, Paddon-Jones D. Artificial gravity maintains skeletal muscle protein synthesis during 21 days of simulated microgravity. J Appl Physiol 2009;107:34-38.
15. Caiozzo VJ, Haddad F, Lee S, Baker M, Paloski W., Baldwin KM. Artificial gravity as a countermeasure to microgravity: A pilot study examining the effects on knee extensor and plantar flexor muscle groups. J Appl Physiol 2009;107:39-46.
16. Stenger MB, Evans JM, Knapp CF, Lee SMC, Phillips TR, Perez SA, Moore AD, Paloski W., Platts SH. Artificial gravity training reduces bed rest-induced cardiovascular deconditioning. Eur J Appl Physiol 2012; 112:605-616.
17. Jarchow T, Young LR. Neurovestibular effects of bed rest and centrifugation. J Vestib Res 2010;20:45-51.
18. Moore S, MacDougall HG, Paloski W. Effects of headdown bed rest and artificial gravity on spatial orientation. Exp Brain Res 2010;204:617-622.
19. Mehta SK, Crucian B, Pierson DL, Sams C, Stowe RP. Monitoring immune system function and reactivation of latent viruses in the artificial gravity pilot study. J Gravit Physiol 2007;14:21-25.
20. Seaton KA, Slack KJ, Sipes W, Bowie K. Artificial gravity as a multi-system countermeasure: Effects on cognitive function. J Gravit Physiol 2007;14:27-30.
21. Clément G, Bukley A. (eds)Artificial gravity. New York: Springer; 2007.
22. Reschke MF, Bloomberg JJ, Harm DL, Paloski W., Layne C, McDonald V. Posture, locomotion, spatial orientation, and motion sickness as a function of space flight. Brain Res Rev 1998;28:102-117.
23. Paloski W., Reschke MF, Black FO, Doxey DD, Harm DL. Recovery of postural equilibrium control following spaceflight. Ann NY Acad Sci 1992;656:747-754.
24. Mulavara AP, Feiveson AH, Fiedler J, Cohen H, Peters BT, Miller C, Brady R, Bloomberg JJ. Locomotor function after long-duration space flight: Effects and motor learning during recovery. Exp Brain Res 2010;202:649-659.
25. Horak F, Hlavacka F. Somatosensory loss increases vestibulospinal sensitivity. J Neurophysiol 2001;86:575-585.
26. Mulavara AP, Ruttley T, Cohen HS, et al. Vestibular-somatosensory convergence in head movement control during locomotion after long-duration space flight. J Vestib Res 2012;22:153-166.
27. Yates BJ, Bronstein AM. The effects of vestibular system lesions on autonomic regulation: observations, mechanisms, and clinical implications. J Vestib Res 2005; 15:119-129.
28. Mulder E, Frings-Meuthen P, von der Wiesche M, Clément G, Linnarsson D, Paloski W., Wuyts F, Zange J, Rittweger J. Study protocol, implementation, and verification of a short versatile upright exercise regime during 5 days of bed rest. J Musculoskelet Neuronal Interac 2014;14:111-123.
29. Black FO. What can posturography tell us about vestibular function? Ann NY Acad Sci 2001;942:446-464.
30. Black FO, Wall C, Nashner LM. Effects of visual and support surface orientation references upon postural control in vestibular deficit subjects. Acta Otolaryngol 1983; 95:199-210.
31. Paloski W., Wood SJ, Feiveson AH, Black FO, Hwang EY, Reschke MF. Destabilization of human balance control by static and dynamic head tilts. Gait Posture 2006; 23:315-323.
32. Jain V, Wood SJ, Feiveson AH, Black FO, Paloski W. Diagnostic accuracy of dynamic posturography testing after short-duration spaceflight. Aviat Space Environ Med 2010;81:625-631
33. Nashner LM. Computerized dynamic posturography: Clinical applications.In: Jacobson GP, Newman CW, Kartush JM, editors. Handbook of Balance Function Testing. Chicago, IL: Mosby-Year Book Inc,; 1993. p. 308-334.
34. Shumway-Cook A, Baldwin M, Polissar NL, Gruber W. Predicting the probability for falls in community-dwelling older adults. Physical Therapy 2007;77:812-819.
35. Feiveson AH, Metter EJ and Paloski WH. A statistical model for interpreting computerized dynamic posturography data. IEEE Transactions on Biomedical Engineering 2002;49:300-309.
36. Paloski W., Black FO, Reschke MF, Calkins DS, Shupert C. Vestibular ataxia following shuttle flights: effects of microgravity on otolith-mediated sensorimotor control of posture. Am J Otol 1993;14:9-17.
37. Wood SJ, Fiedler J, Taylor LC, Sayenko D, Kozlovskaya I, Black FOPaloski W., Comparison of postural recovery after short and long duration spaceflights. Proceedings of 8th Symposium on the Role of Vestibular Organs in Space Exploration, Houston, TX, May 5-9, 2011.
38. Reschke MF, Bloomberg JJ, Paloski W., Mulavara AP, Feiveson AH, Harm DL. Postural reflexes, balance control, and functional mobility with long-duration headdown bed rest. Aviat Space Environ Med 2009; 80:A45-A54.
39. Young LR, WH Paloski. Short radius intermittent centrifugation as a countermeasure tobed-rest and 0-G deconditioning: IMAG pilot study summary and recommendations for research. J Gravit Physiol 2007; 14:P31-P33.
40. Watt DG, Money KE, Tomi LM. M.I.T./Canadian vestibular experiments on the Spacelab-1 mission: 3. Effects of prolonged weightlessness on a human otolithspinal reflex. Exp Brain Res 1986;64:308-315.
41. Bloomberg JJ, Mulavara AP. Changes in walking strategies after spaceflight. IEEE Eng Med Biol Mag 2003; 22:58-62.
42. Clément G, Gurfinkel VS, Lestienne F, Lipshits MI, Popov KE. Adaptation of postural control to weightlessness. Exp Brain Res 1984;57:61-72.
43. Reschke MF, Anderson DJ, Homick JL. Vestibulospinal reflexes as a function of microgravity. Science 1984; 225:212-214.
44. Newman DJ, Jackson DK, Bloomberg JJ. Altered astronaut lower limb and mass center kinematics in downward jumping following space flight. Exp Brain Res 1997; 117:30-42.
45. Dietz V, Duysens J. Significance of load receptor input during locomotion: a review. Gait Posture 2000;11:102-110.
46. Perry SD, Santos LC, Patla AE. Contribution of vision and cutaneous sensation to the control of centre of mass (COM) during gait termination. Brain Res 2001;913:27-34.