Locomotor function after long-duration space flight: Effects and motor learning during recovery

Experimental Brain Research

Volumn 202, Issue 3, 2010, Pages 649-659

  Mulavara, Ajitkumar P ^a   Feiveson, Alan H ^b   Fiedler, James ^a   Cohen, Helen ^c   Peters, Brian T ^d   Miller, Chris ^d   Brady, Rachel ^d   Bloomberg, Jacob J ^b  

^a UNIVERSITIES SPACE RESEARCH ASSOCIATION   (United States)

^b NASA JOHNSON SPACE CENTER   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d WYLE LABORATORIES   (United States)

Author keywords

Adaptation; Functional mobility; Locomotion; Recovery; Space flight

Indexed keywords

ADAPTATION; ADULT; AEROSPACE MEDICINE; ARTICLE; FEMALE; FUNCTIONAL STATUS; GRAVITY SENSING; HUMAN; HUMAN EXPERIMENT; LOCOMOTION; MALE; MOTOR CONTROL; PHYSICAL MOBILITY; PHYSICAL PERFORMANCE; PRIORITY JOURNAL; SENSORIMOTOR FUNCTION; SPACE FLIGHT; WALKING DIFFICULTY;

ADULT; ASTRONAUTS; FEMALE; HUMANS; LEARNING; LOCOMOTION; MALE; MIDDLE AGED; MOVEMENT DISORDERS; RECOVERY OF FUNCTION; SPACE FLIGHT; TASK PERFORMANCE AND ANALYSIS; TIME FACTORS; WEIGHTLESSNESS;

EID: 77951090931     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-010-2171-0     Document Type: Article

References (63)

1. Anguera JA, Reuter-Lorenz PA, Willingham DT, Seidler RD (2009) Contributions of spatial working memory to visuomotor learning. J Cogn Neurosci (in press)
2. G Antonutto C Capelli M Girardis P Zamparo PE di Prampero 1999 Effects of microgravity on maximal power of lower limbs during very short efforts in humans J Appl Physiol 86 85 92 1:STN:280:DyaK1M7gsVWrtQ%3D%3D 9887117
3. JJ Bloomberg AP Mulavara 2003 Changes in walking strategies after spaceflight IEEE Eng Med Biol Mag 22 58 62 10.1109/MEMB.2003.1195697 12733460 (Pubitemid 37328142)
4. JJ Bloomberg BT Peters SL Smith WP Huebner MF Reschke 1997 Locomotor head-trunk coordination strategies following space flight J Vestib Res 7 161 177 10.1016/S0957-4271(96)00169-3 1:STN:280:DyaK2szitFGjsw%3D%3D 9178222
5. O Bock 2005 Components of sensorimotor adaptation in young and elderly subjects Exp Brain Res 160 259 263 10.1007/s00221-004-2133-5 15565436 (Pubitemid 40104514)
6. O Bock M Girgenrath 2006 Relationship between sensorimotor adaptation and cognitive functions in younger and older subjects Exp Brain Res 169 400 406 10.1007/s00221-005-0153-4 16328306 (Pubitemid 43356331)
7. R Boyle AF Mensinger K Yoshida S Usui A Intravaia T Tricas SM Highstein 2001 Neural readaptation to Earth's gravity following return from space J Neurophysiol 86 2118 2122 1:STN:280:DC%2BD3Mrltlehsg%3D%3D 11600668
8. Bryanov II, Yemel'yanov MD, Matveyev AD, Mantsev EI, Tarasov IK, Yakovleva IK, Kakurin LI, Kozerenko OP, Myasnikov VI, Yeremin AV, Pervishin VI, Cherepakin MA, Purakhin YN, Rudometkin NM VCI (1976) Space flights in the Soyuz spacecraft: biomedical research. Leo Kanner Associates, Redwood City
9. IF Chekirda AV Bogdashevskiy AV Yeremin IA Kolosov 1971 Coordination structure of walking of Soyuz-9 crew members before and after flight Kosm Biol Med 5 48 52
10. Clement G, Reschke MF (2008) Neuroscience in space. Springer, New York
11. DM Clower D Boussaoud 2000 Selective use of perceptual recalibration versus visuomotor skill acquisition J Neurophysiol 84 2703 2708 1:STN:280:DC%2BD3M%2FmvFOhug%3D%3D 11068013
12. G Courtine T Pozzo 2004 Recovery of the locomotor function after prolonged microgravity exposure. I. Head-trunk movement and locomotor equilibrium during various tasks Exp Brain Res 158 86 99 10.1007/s00221-004- 1877-2 15164151 (Pubitemid 39208528)
13. Edgerton VR, Roy RR (1996) Neuromuscular adaptations to actual adn simulated spaceflight. In: Handbook of physiology, environmental physiology, vol III. American Physiological Society, Bethesda, pp 721-763
14. RH Fitts DR Riley JJ Widrick 2000 Physiology of a microgravity environment invited review: microgravity and skeletal muscle J Appl Physiol 89 823 839 1:CAS:528:DC%2BD3cXmtleltLw%3D 10926670
15. Gibbons JD, Chakraborti S (2003) Nonparametric statistical inference. Marcel Dekker, New York
16. S Glasauer MA Amorim JJ Bloomberg MF Reschke BT Peters SL Smith A Berthoz 1995 Spatial orientation during locomotion (correction of locomation) following space flight Acta Astronaut 36 423 431 10.1016/0094-5765(95)00127-1 1:STN:280:DC%2BD3MnlvFGntw%3D%3D 11540973
17. BA Harris Jr RD Billica SL Bishop T Blackwell CS Layne DL Harm GR Sandoz EC Rosenow III 1997 Physical examination during space flight Mayo Clin Proc 72 301 308 10.4065/72.4.301 9121174
18. J Jeka T Kiemel R Creath F Horak R Peterka 2004 Controlling human upright posture: velocity information is more accurate than position or acceleration J Neurophysiol 92 4 2368 2379 10.1152/jn.00983.2003 15140910 (Pubitemid 39298689)
19. A Karni G Bertini 1997 Learning perceptual skills: behavioral probes into adult cortical plasticity Curr Opin Neurobiol 7 530 535 10.1016/S0959-4388(97) 80033-5 1:STN:280:DyaK2svjtleluw%3D%3D 9287202 (Pubitemid 28102561)
20. A Karni D Sagi 1993 The time course of learning a visual skill Nature 365 250 252 10.1038/365250a0 1:STN:280:DyaK3szot1Ggsw%3D%3D 8371779 (Pubitemid 23282082)
21. KP Kording JB Tenenbaum R Shadmehr 2007 The dynamics of memory as a consequence of optimal adaptation to a changing body Nat Neurosci 10 779 786 10.1038/nn1901 1:CAS:528:DC%2BD2sXls1Kgsbk%3D 17496891 (Pubitemid 46828507)
22. IB Kozlovskaya V Kreidich Yu VS Oganov OP Koserenko 1981 Pathophysiology of motor functions in prolonged manned space flights Acta Astronaut 8 1059 1072 10.1016/0094-5765(81)90079-5 1:STN:280:DC%2BD3MnmtFKktQ%3D%3D 11543096
23. CS Layne PV McDonald JJ Bloomberg 1997 Neuromuscular activation patterns during treadmill walking after space flight Exp Brain Res 113 104 116 10.1007/BF02454146 1:STN:280:DyaK2s7otVKjsQ%3D%3D 9028779 (Pubitemid 27039296)
24. CS Layne GW Lange CJ Pruett PV McDonald LA Merkle AP Mulavara SL Smith IB Kozlovskaya JJ Bloomberg 1998 Adaptation of neuromuscular activation patterns during treadmill walking after long-duration space flight Acta Astronaut 43 107 119 10.1016/S0094-5765(98)00148-9 1:STN:280:DC%2BD3MnmtVCqsg%3D%3D 11541918
25. CS Layne AP Mulavara PV McDonald CJ Pruett IB Kozlovskaya JJ Bloomberg 2001 Effect of long-duration spaceflight on postural control during self-generated perturbations J Appl Physiol 90 997 1006 1:STN:280: DC%2BD3M3ksFeksQ%3D%3D 11181611
26. CS Layne AP Mulavara PV McDonald CJ Pruett IB Kozlovskaya JJ Bloomberg 2004 Alterations in human neuomuscular acivation during overground locmotion after long-duration spaceflight J Gravit Physiol 11 1 16
27. J Luauté S Schwartz Y Rossetti M Spiridon G Rode D Boisson P Vuilleumier 2009 Dynamic changes in brain activity during prism adaptation J Neurosci 29 1 169 178 10.1523/JNEUROSCI.3054-08.2009 19129395
28. DS Marigold AE Patla 2005 Adapting locomotion to different surface compliances: neuromuscular responses and changes in movement dynamics J Neurophysiol 94 3 1733 1750 10.1152/jn.00019.2005 15888535 (Pubitemid 41192846)
29. P Mazzoni JW Krakauer 2006 An implicit plan overrides an explicit strategy during visuomotor adaptation J Neurosci 26 14 3642 3645 10.1523/JNEUROSCI.5317-05.2006 1:CAS:528:DC%2BD28Xjs1yks78%3D 16597717
30. PV McDonald C Basdogan JJ Bloomberg CS Layne 1996 Lower limb kinematics during treadmill walking after space flight: implications for gaze stabilization Exp Brain Res 112 325 334 10.1007/BF00227650 1:STN:280:DyaK2s7gvFWhsg%3D%3D 8951400
31. EC McNay DB Willingham 1998 Deficit in learning of a motor skill requiring strategy, but not of perceptuomotor recalibration, with aging Learn Mem 4 411 420 10.1101/lm.4.5.411 1:STN:280:DC%2BD3c7mtlyitw%3D%3D 10701880
32. Mueller C, Kornilova L, Wiest, G, Deecke L (1992) Optovert-vertical optokinetic stimulation used to examine central orientational processes. In: Health from space research, Austrian accomplishments. Springer, New York, pp 155-165
33. Mueller C, Kornilova L, Wiest G, Steinhoff N, Deecke L (1994) Results from vertical vection experiments in short and long term space flights. In: Proceedings of the 5th European symposium on life sciences research in space, ESA SP-366, Arcachon, France, CNES/ESA 1994, pp 373-376
34. DJ Newman DK Jackson JJ Bloomberg 1997 Altered astronaut lower limb and mass center kinematics in downward jumping following space flight Exp Brain Res 117 30 42 10.1007/PL00005788 1:STN:280:DyaK1c%2FksFOluw%3D%3D 9386002 (Pubitemid 27448029)
35. CM Oman BK Lichtenberg KE Money RK McCoy 1986 M.I.T./Canadian vestibular experiments on the Spacelab-1 mission: 4. Space motion sickness: symptoms, stimuli, and predictability Exp Brain Res 64 316 334 10.1007/BF00237749 1:STN:280:DyaL2s7gsFOiug%3D%3D 3803476
36. CM Oman IP Howard T Carpenter-Smith AC Beall A Natapoff JE Zacher HL Jenkin 2000 Neurolab experiments on the role of visual cues in microgravity spatial orientation Aviat Space Environ Med 71 3 283
37. Paloski WH (1998) Control of posture and movement. In: Winters J, Crago P (eds) Neuro-musculo-skeletal interaction and organizational principles. Springer, Heidelberg
38. WH Paloski MF Reschke FO Black DD Doxey DL Harm 1992 Recovery of postural equilibrium control following spaceflight Ann N Y Acad Sci 656 747 754 10.1111/j.1749-6632.1992.tb25253.x 1:STN:280:DyaK383os1KrtA%3D%3D 1599180
39. WH Paloski JJ Bloomberg MF Reschke DL Harm 1994 Spaceflight induced changes in posture and locomotion J Biomech 27 812 10.1016/0021-9290(94)91366-8
40. L Pisella C Michel H Grea C Tilikete A Vighetto Y Rossetti 2004 Preserved prism adaptation in bilateral optic ataxia: strategic versus adaptive reaction to prisms Exp Brain Res 156 399 408 10.1007/s00221-003-1746-4 1:STN:280:DC%2BD2c3msl2jug%3D%3D 15133651 (Pubitemid 38822606)
41. GM Redding B Wallace 1996 Adaptive spatial alignment and strategic perceptual-motor control J Exp Psychol Hum Percept Perform 22 379 394 10.1037/0096-1523.22.2.379 1:STN:280:DyaK2s%2FovV2nsQ%3D%3D 8934851
42. GM Redding B Wallace 2002 Strategic calibration and spatial alignment: a model from prism adaptation J Mot Behav 34 126 138 10.1080/00222890209601935 12057886
43. MF Reschke DE Parker 1987 Effects of prolonged weightlessness on self-motion perception and eye movements evoked by roll and pitch Aviat Space Environ Med 58 A153 A158 1:STN:280:DyaL1c%2FkvFGjtA%3D%3D 3675483
44. MF Reschke DJ Anderson JL Homick 1986 Vestibulo-spinal response modification as determined with the H-reflex during the Spacelab-1 flight Exp Brain Res 64 367 379 10.1007/BF00237753 1:STN:280:DyaL2s7gsFOhsA%3D%3D 3492388
45. Reschke MF, Kornilova LN, Harm DL, Bloomberg JJ, Paloski WH (1996) Nurosensory and sensory-motor function. In: Nicogossian AE, Mohler SR, Gazenko OG, Grigoriev AI (eds) Space biology and medicine. III. Humans in space flight. American Institute of Aeronautics and Astronautics, Reston
46. MF Reschke JJ Bloomberg DL Harm WH Paloski C Layne V McDonald 1998 Posture, locomotion, spatial orientation, and motion sickness as a function of space flight Brain Res Brain Res Rev 28 102 117 10.1016/S0165-0173(98)00031-9 1:STN:280:DyaK1M%2FhtlyntQ%3D%3D 9795167 (Pubitemid 28513057)
47. JT Richards AP Mulavara JJ Bloomberg 2007 The interplay between strategic and adaptive control mechanisms in plastic recalibration of locomotor function Exp Brain Res 178 326 338 10.1007/s00221-006-0738-6 17061092 (Pubitemid 46440579)
48. JP Roll K Popov V Gurfinkel M Lipshits AC Deshays JC Gilhodes C Quoniam 1993 Sensorimotor and perceptual function of muscle proprioception in microgravity J Vestib Res 3 259 273 1:STN:280:DyaK2c7gtFentw%3D%3D 8275261
49. R Roll JC Gilhodes JP Roll K Popov O Charade V Gurfinkel 1998 Proprioceptive information processing in weightlessness Exp Brain Res 122 4 393 402 10.1007/s002210050527 1:STN:280:DyaK1M%2FktlGlsg%3D%3D 9827858 (Pubitemid 28457136)
50. Y Rossetti K Koga T Mano 1993 Prismatic displacement of vision induces transient changes in the timing of eye-hand coordination Percept Psychophys 54 355 364 1:STN:280:DyaK2c%2FitFalsQ%3D%3D 8414894
51. RD Seidler 2004 Multiple motor learning experiences enhance motor adaptability J Cogn Neurosci 16 65 73 10.1162/089892904322755566 15006037 (Pubitemid 38117587)
52. R Shadmehr FA Mussa-Ivaldi 1994 Adaptive representation of dynamics during learning of a motor task J Neurosci 14 3208 3224 1:STN:280: DyaK2c3jvVekuw%3D%3D 8182467
53. JD Sibonga HJ Evans HG Sung ER Spector TF Lang VS Oganov AV Bakulin LC Shackelford AD LeBlanc 2007 Recovery of spaceflight-induced bone loss: bone mineral density after long-duration missions as fitted with an exponential function Bone 41 973 978 10.1016/j.bone.2007.08.022 1:STN:280: DC%2BD2snpsVyktA%3D%3D 17931994 (Pubitemid 350116745)
54. MA Smith A Ghazizadeh R Shadmehr 2006 Interacting adaptive processes with different timescales underlie short-term motor learning PLoS Biol 4 e179 10.1371/journal.pbio.0040179 16700627
55. L Vico P Collet A Guignandon MH Lafage-Proust T Thomas M Rehaillia C Alexandre 2000 Effects of long-term microgravity exposure on cancellous and cortical weight-bearing bones of cosmonauts Lancet 355 1607 1611 10.1016/S0140-6736(00)02217-0 1:STN:280:DC%2BD3c3nvFertw%3D%3D 10821365
56. DG Watt KE Money RL Bondar RB Thirsk M Garneau P Scully-Power 1985 Canadian medical experiments on Shuttle flight 41-G Can Aeronaut Space J 31 215 226 1:STN:280:DC%2BD3Mnlsleqtg%3D%3D 11538834
57. DGD Watt KE Money LM Tomi 1986 M.I.T./Canadian vestibular experiments on the Spacelab-1 mission. 3. Effects of prolonged weightlessness on a human otolith-spinal reflex Exp Brain Res 64 308 315 10.1007/BF00237748 1:STN:280:DyaL2s7gsFOitQ%3D%3D 3803475
58. DG Watt JP Landolt LR Young 1993 Effects of long-term weightlessness on roll circular vection Can Aeronaut Space J 39 1 52 55
59. MJ Weiner M Hallett HH Funkenstein 1983 Adaptation to lateral displacement of vision in patients with lesions of the central nervous system Neurology 33 766 772 1:STN:280:DyaL3s7pt12mtA%3D%3D 6682520
60. RB Welch B Bridgeman S Anand KE Browman 1993 Alternating prism exposure causes dual adaptation and generalization to a novel displacement Percept Psychophys 54 195 204 1:STN:280:DyaK3szmvFSmtQ%3D%3D 8361835
61. LR Young M Shelhamer 1990 Microgravity enhances the relative contribution of visually-induced motion sensation Aviat Space Environ Med 61 525 530 1:STN:280:DyaK3czhsV2hug%3D%3D 2369392
62. LR Young CM Oman DGD Watt KE Money BK Lichtenberg 1984 Spatial orientation in weightlessness and readaptation to Earth's gravity Science 225 205 208 10.1126/science.6610215 1:STN:280:DyaL2c3itl2rsQ%3D%3D 6610215
63. LR Young DK Jackson N Groleau S Modestino 1992 Multisensory integration in microgravity Ann N Y Acad Sci 682 340 353 10.1111/j.1749-6632.1992.tb25220.x