Development of a cell-based treatment for long-term neurotrophin expression and spiral ganglion neuron survival

Neuroscience

Volumn 277, Issue , 2014, Pages 690-699

  Zanin, M P ^a,d   Hellstrom M ^c,e   Shepherd, R K ^a,b   Harvey, A R ^c   Gillespie, L N ^a,b  

^a BIONICS INSTITUTE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^e UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Lentivirus; Lipofection; Neurotrophin; Nucleofection; Sensorineural hearing loss; Spiral ganglion neuron

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; LENTIVIRUS VECTOR; NEUROTROPHIN; NEUROTROPHIN 3; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; NERVE GROWTH FACTOR; NEUROTROPHIN-3, HUMAN;

ANIMAL CELL; ARTICLE; BDNF GENE; CELL BASED GENE THERAPY; CELL CULTURE; CELL SURVIVAL; CONTROLLED STUDY; FIBROBLAST; GENE; IN VITRO STUDY; IN VIVO STUDY; NERVE CELL; NONHUMAN; NT3 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; SCHWANN CELL; SPIRAL GANGLION; VIRAL GENE DELIVERY SYSTEM; ANIMAL; BIOLOGICAL THERAPY; COCULTURE; CULTURE TECHNIQUE; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; PROCEDURES; SCIATIC NERVE; SECRETION (PROCESS); ACOUSTIC NERVE FIBER; CELL COUNT; LIPOFECTION; NUCLEOFECTION; PROTEIN CONTENT;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CELL- AND TISSUE-BASED THERAPY; COCULTURE TECHNIQUES; FIBROBLASTS; GREEN FLUORESCENT PROTEINS; HUMANS; NERVE GROWTH FACTORS; NEURONS; RATS; SCHWANN CELLS; SCIATIC NERVE; SPIRAL GANGLION; TRANSFECTION;

EID: 84907033634     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.07.044     Document Type: Article

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