Role of neurotrophins on dermal fibroblast survival and differentiation

Journal of Cellular Physiology

Volumn 227, Issue 3, 2012, Pages 1017-1025

  Palazzo, Elisabetta ^a   Marconi, Alessandra ^a   Truzzi, Francesca ^a   Dallaglio, Katiuscia ^a   Petrachi, Tiziana ^a   Humbert, Philippe ^b   Schnebert, Sylvianne ^c   Perrier, Eric ^c   Dumas, Marc ^c   Pincelli, Carlo ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b UNIVERSITÉ DE FRANCHE COMTÉ   (France)

^c Parfums Christian Dior   (France)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTROPHIN; NEUROTROPHIN RECEPTOR; NEUROTROPHIN RECEPTOR P75; PROTEIN TYROSINE KINASE A; SMALL INTERFERING RNA;

ARTICLE; AUTOCRINE EFFECT; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE SILENCING; HUMAN; HUMAN CELL; MYOFIBROBLAST; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN FIBROBLAST; TENSILE STRENGTH; WESTERN BLOTTING; WOUND HEALING;

BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; DERMIS; FIBROBLASTS; FORESKIN; GUIDED TISSUE REGENERATION; HUMANS; MALE; MYOFIBROBLASTS; NERVE GROWTH FACTORS; RECEPTOR, NERVE GROWTH FACTOR; RECEPTOR, TRKA; RECEPTOR, TRKB; RECEPTOR, TRKC; WOUND HEALING;

EID: 84155184245     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22811     Document Type: Article

References (35)

1. Albanesi C, Scarponi C, Pallotta S, Daniele R, Bosisio D, Madonna S, Fortugno P, Gonzalvo-Feo S, Franssen JD, Parmentier M, De Pità O, Girolomoni G, Sozzani S. 2009. Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment. J Exp Med 206: 249-258.
2. Aloe L, Tirassa P, Lambiase A. 2008. The topical application of nerve growth factor as a pharmacological tool for human corneal and skin ulcers. Pharmacol Res 57: 253-258.
3. Botchkarev VA, Yaar M, Peters EM, Raychaudhuri SP, Botchkareva NV, Marconi A, Raychaudhuri SK, Paus R, Pincelli C. 2006. Neurotrophin in skin biology and pathology. J Invest Dermatol 126: 1719-1727.
4. Desmoulière A, Redard M, Darby I, Gabbiani G. 1995. Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar. Am J Pathol 146: 56-66.
5. Desmoulière A, Darby I, Gabbiani G. 2003. Normal and pathologic soft tissue remodeling: Role of the myofibroblast, with special emphasis on liver and kidney fibrosis. Lab Invest 37: 109-204.
6. Desmoulière A, Chaponnier C, Gabbiani G. 2005. Tissue repair, contraction, and the myofibroblast. Wound Repair Regen 13: 7-12.
7. Ernsberger U. 2009. Role of neurotrophin signalling in the differentiation of neurons from dorsal root ganglia and sympathetic ganglia. Cell Tissue Res 336: 349-384.
8. Hasan W, Zhang R, Liu M, Warm JD, Smith PG. 2000. Coordinate expression of NGF and a-smooth muscle actin mRNA and protein in cutaneous wound tissue of developing and adult rats. Cell Tissue Res 300: 97-109.
9. Hattori A, Hayashi K, Kohno M. 1996. Tumor necrosis factor (TNF) stimulates the production of nerve growth factor in fibroblasts via the 55-kDa type 1 TNF receptor. FEBS Lett 379: 157-160.
10. Hinz B. 2007. Formation and function of the myofibroblast during tissue repair. J Invest Dermatol 127: 526-537.
11. Kendall TJ, Hennedige S, Aucott RL, Hartland SN, Vernon MA, Benyon RC, Iredale JP. 2009. p75 Neurotrophin receptor signaling regulates hepatic myofibroblast proliferation and apoptosis in recovery from rodent liver fibrosis. Hepatology 49: 901-910.
12. Krieg T, Abraham D, Lafyatis R. 2007. Fibrosis in connective tissue disease: The role of the myofibroblast and fibroblast-epithelial cell interactions. Arthritis Res Ther 9: S4. (doi: 10.1186/ar2188)
13. Landi F, Aloe L, Russo A, Cesari M, Onder G, Bonini S, Carbonin PU, Bernabei R. 2003. Topical treatment of pressure ulcers with nerve growth factor. A randomized clinical trial. Ann Int Med 139: 635-641.
14. Li L, Dragulev B, Zigrino P, Mauch C, Fox JW. 2009. The invasive potential of human melanoma cell lines correlates with their ability to alter fibroblast gene expression in vitro and the stromal microenvironment in vivo. Int J Cancer 125: 1796-1804.
15. Marconi A, Terracina M, Fila C, Franchi J, Bonté F, Romagnoli G. 2003. Expression and function of neurotrophins and their receptors in cultured human keratinocytes. J Invest Dermatol 121: 1515-1521. Erratum in: 2004. J Invest Dermatol 123: 803.
16. Marconi A, Panza MC, Bonnet-Duquennoy M, Lazou K, Kurfurst R, Truzzi F, Lotti R, De Santis G, Dumas M, Bonté F, Pincelli C. 2006. Expression and function of neurotrophins and their receptors in human melanocytes. Int J Cosmet Sci 28: 255-261.
17. Micera A, Vigneti E, Pickholtz D, Reich R, Pappo O, Bonini S, Maquart FX, Aloe L, Levi-Schaffer F. 2001. Nerve growth factor displays stimulatory effects on human skin and lung fibroblasts, demonstrating a direct role for this factor in tissue repair. Proc Natl Acad Sci USA 98: 6162-6167.
18. Micera A, Lambiase A, Puxeddu I, Aloe L, Stampachiacchiere B, Levi-Schaffer F, Bonini S, Bonini S. 2006. Nerve growth factor effect on human primary fibroblastic-keratocytes: Possible mechanism during corneal healing. Exp Eye Res 83: 747-757.
19. Micera A, Lambiase A, Stampachiacchiere B, Bonini S, Bonini S, Levi-Schaffer F. 2007a. Nerve growth factor and tissue repair remodeling: trkA(NGFR) and p75(NTR), two receptors one fate. Cytokine Growth Factor Rev 18: 245-256.
20. Micera A, Lambiase A, Stampachiacchiere B, Sgrulletta R, Normando EM, Bonini S, Bonini S. 2007b. Nerve growth factor has a modulatory role on human primary fibroblast cultures derived from vernal keratoconjunctivitis-affected conjunctiva. Mol Vis 13: 981-987.
21. Peters EM, Raap U, Welker P, Tanaka A, Matsuda H, Pavlovic-Masnicosa S, Hendrix S, Pincelli C. 2007. Neurotrophins act as neuroendocrine regulators of skin homeostasis in health and disease. Horm Metab Res 39: 110-124.
22. Pincelli C, Sevignani C, Manfredini R, Grande A, Fantini F, Bracci Laudiero L, Aloe L, Ferrari S, Cossarizza A, Giannetti A. 1994. Expression and function of nerve growth factor and nerve growth factor receptor on cultured keratinocytes. J Invest Dermatol 103: 13-18.
23. Poduslo JF, Curran GL, Gill JS. 1998. Putrescine-modified nerve growth factor: Bioactivity, plasma pharmacokinetics, blood-brain/nerve barrier permeability, and nervous system biodistribution. J Neurochem 71: 1651-1660.
24. Raap U, Kapp A. 2010. Neurotrophins in healthy and diseased skin. G Ital Dermatol Venereol 145: 205-211.
25. Rhee S. 2009. Fibroblasts in three dimensional matrices: Cell migration and matrix remodeling. Exp Mol Med 41: 858-865.
26. Saalbach A, Klein C, Schirmer C, Briest W, Anderegg U, Simon JC. 2010. Dermal fibroblasts promote the migration of dendritic cells. J Invest Dermatol 130: 444-454.
27. Schirmer C, Klein C, von Bergen M, Simon JC, Saalbach A. 2010. Human fibroblasts support the expansion of IL-17 producing T-cells via up-regulation of IL-23 production by dendritic cells. Blood 116: 1715-1725.
28. Snider WD. 1994. Functions of the neurotrophins during nervous system development: What the knockouts are teaching us. Cell 77: 627-638.
29. Spittau G, Happel N, Behrendt M, Chao TI, Krieglstein K, Spittau B. 2010. Tieg1/Klf10 is upregulated by NGF and attenuates cell cycle progression in the pheochromocytoma cell line PC12. J Neurosci Res 88: 2017-2025.
30. Sun W, Lin H, Chen B, Zhao W, Zhao Y, Xiao Z, Dai J. 2010. Collagen scaffolds loaded with collagen-binding NGF-beta accelerate ulcer healing. J Biomed Mater Res A 92: 887-895.
31. Truzzi F, Marconi A, Lotti R, Dallaglio K, French LE, Hempstead BL, Pincelli C. 2008. Neurotrophins and their receptors stimulate melanoma cell proliferation and migration. J Invest Dermatol 128: 2031-2040.
32. Viennet C, Bride J, Armbruster V, Aubin F, Gabiot AC, Gharbi T, Humbert P. 2005. Contractile forces generated by striae distensae fibroblasts embedded in collagen lattices. Arch Dermatol Res 297: 10-17.
33. Walter M.N., Wright KT, Fuller HR, MacNeil S, Johnson WE. 2010. Mesenchymal stem cell-conditioned medium accelerates skin wound healing: an in vitro study of fibroblast and keratinocyte scratch assays. Exp Cell Res. 316: 1271-1281.
34. Werner S, Krieg T, Smola H. 2007. Keratinocyte-fibroblast interaction in wound healing. J Invest Dermatol 127: 998-1008.
35. Wu CS, Lan CC, Chiou MH, Yu HS. 2006. Basic fibroblast growth factor promotes melanocyte migration via increased expression of p125(FAK) on melanocytes. Acta Derm Venereol 86: 498-502.