Platelets promote mitochondrial uncoupling and resistance to apoptosis in leukemia cells: A novel paradigm for the bone marrow microenvironment

Cancer Microenvironment

Volumn 7, Issue 1-2, 2014, Pages 79-90

  Velez, Juliana ^a,b   Enciso, Leonardo José ^b   Suarez, Marta ^b   Fiegl, Michael ^c   Grismaldo, Adriana ^a   López, Catalina ^d   Barreto, Alfonso ^a   Cardozo, Claudia ^e   Palacios, Pilar ^e   Morales, Ludis ^a   Duque, Jorge Eduardo ^a   Carmona, Jorge Uriel ^d   Konopleva, Marina ^f   Andreeff, Michael ^f   Samudio, Ismael ^a,b,g  

^a PONTIFICIA UNIVERSIDAD JAVERIANA   (Colombia)

^b Instituto Nacional de Cancerología   (Colombia)

^c UNIVERSITY OF MUNICH   (Germany)

^d UNIVERSIDAD DE CALDAS   (Colombia)

^e HOSPITAL UNIVERSITARIO SAN IGNACIO   (Colombia)

^f UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^g BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

ABT 737; Apoptosis; CDDO Me; Fatty acid oxidation; Leukemia; Metabolism; Mitochondrial uncoupling; Platelets

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; BARDOXOLONE METHYL; PADGEM PROTEIN; PHOSPHATIDYLSERINE; PROTEIN BAX; RANOLAZINE; SUPEROXIDE; TRIACYLGLYCEROL;

ADULT; AGED; APOPTOSIS; ARTICLE; BONE MARROW; CELL CULTURE; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; FATTY ACID OXIDATION; FEMALE; HUMAN; HUMAN CELL; LEUKEMIA CELL; LIPOLYSIS; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; OLIGOMERIZATION; OXIDATIVE PHOSPHORYLATION UNCOUPLING; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; THROMBOCYTE ACTIVATION; THROMBOCYTE RICH PLASMA; TUMOR MICROENVIRONMENT;

EID: 84907018289     PISSN: 18752292     EISSN: 18752284     Source Type: Journal    
DOI: 10.1007/s12307-014-0149-3     Document Type: Article

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