Paclitaxel poly lactide-co-glycolic acid nanoparticles inhibit human hepatocellular carcinoma cells HepG2

Chinese Journal of Tissue Engineering Research

Volumn 17, Issue 3, 2013, Pages 412-418

  Pang, Li Yun ^a   Wang, Hai ^a   Chen, Yong Xia ^a   Liu, Shuai ^a   Yang, Jing ^a   Sun, Hong Fan ^a  

^a INSTITUTE OF BIOMEDICAL ENGINEERING   (China)

Author keywords

Apoptosis; Biomaterial photographs containing paper; Biomaterials; Hepatic carcinoma; Nano biological materials; Nanoparticles; National natural science foundation of China; Paclitaxel; Poly lactide co glycolic acid copolymer; Sustained release drugs

Indexed keywords

NANOPARTICLE; PACLITAXEL; POLYGLACTIN;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CONCENTRATION RESPONSE; HEPG2 CELL LINE; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MTT ASSAY;

EID: 84907003829     PISSN: 16738225     EISSN: None     Source Type: Journal    
DOI: 10.3969/j.issn.2095-4344.2013.03.006     Document Type: Article

References (22)

1. Wu B, Yang ZF. Zhongguo Yaoye. 2004, 13(6):77-78.
2. Xu M, Takanashi M, Oikawa K, et al. Identification of a novel role of Septin 10 in paclitaxel-resistance in cancers through a functional genomics screen. Cancer Sci. 2012; 103(4): 821-827.
3. Dong XL, Xu PF, Miao C, et al. Hypoxia decreased chemosensitivity of breast cancer cell line MCF-7 to paclitaxel through cyclin B1. Biomed Pharmacother. 2012;66(1):70-75.
4. Li S, Liao H, Zhan J, et al. Zhongguo Linchuang Yaolixue Zazhi. 2008, 26(8):606-610.
5. Ma GL, Miao Bl, Song CXThermosensitive PCL-PEG-PCL hydrogels: Synthesis, characterization, and delivery of proteins. J Appl Polym Sci. 2010;116(4):1985-1993.
6. Xu YJ. Suzhou Daxue. 2008.
7. Lee KC, Maturo C, Rodriguez R, et al. Nanomedicine-nanoemulsion. Formulation improves safety and efficacy of the anti-cancer drag paclitaxel according to preclinical assessment. J Nanosci Nanotechnol. 2011; 11(8): 6642-6656.
8. Yang J, Bao B, Chen YX, et al. Zhongguo Zuzhi Gongcheng Yanjiu. 2012;16(16):2869-2874.
9. Gong C, Shi S, Wu L, et al. Biodegradable in situ gel-forming controlled drug delivery system based on thermosensitive PCL-PEG-PCL hydrogel. Part 2: sol-gel-sol transition and drug delivery behavior. Acta Biomater. 2009;5(9):3358-3370.
10. Bea SJ, Suh JM, Sohn YS, et al. Thermogelling Poly(caprolactone-b-ethylene glycol-b-caprolactone)aqueous solutions. Macromolecules. 2005;38(12):5260-5265.
11. Chao G, Fan L, Jia W, et al. Synthesis, characterization and hydrolytic degradation of degrable poly(butyleneterephthalate)/poly(ethlene glycol)(PBT/PEG)copolymers. J Mater Sci Mater Med. 2007;18(3):449-455.
12. Jeong B, Bae YH, Lee DS, et al. Biodegradable block copolymers as injectable drug- delivery system. Nature. 1997;388(6645):860-862.
13. Ron ES, Bromberg LE. Temperature-responsive gels and thermogelling polymer matrices for protein and peptide delivery. Adv Drug Deliv Rev. 1998;31(3):197-221.
14. Dong Y, Feng SS. Methoxy poly(ethyleneglycol)-poly(lactide)(MPEG-PLA)nanoparticles for controlled delivery of anticancer drugs. Biomaterials. 2014; 25(14): 2843-2849.
15. Sinha VR, Bansal K, Kaushik R, et al. Poly-epsilon-caprolactone microspheres and nanospheres:an overview. Int J Pharm. 2004;278(1):1-23.
16. Espuelas MS, Legrand P, Lrache JM, et al. Puly(epsihmcaprolacton) nanospheres as an alternative way to reduce amphotericin B toxicity. Int J Pharm. 1997;158(1):19-27.
17. Yang J, Zeng Y, Li Y, Intravascular site-specific delivery of a therapeutic antisense for the inhibition of restenosis. Eur J Pharm Sci. 2008;35(5):427-434.
18. Pan QC, Xu B. Zhengzhou:Henan Yike Daxue Chubanshe. 2000:55.
19. Hickman JA. Apoptosis and chemotherspy resistance. Eur J Cancer. 1996;32:921.
20. Bhalla K, Huany Y, Tang C, et al. Taxol induces intemucleosomal DNA fragmentation associated with programmed cell death in human myeloid leukemia cell. Leukemia. 1993;7:563.
21. Donaldson KL, Goolsby G, Kiener PA, et al. Activation of p34cdc2 coincident with taxol-induced apoptosis. Cell Growth Differ. 1994;5:1041.
22. Chen LR, Zheng S, Willingham MC, et al. Zhonghua Zhongliu Zazhi. 1997;19(2):103.