Computer simulations reveal complex distribution of haemodynamic forces in a mouse retina model of angiogenesis

Journal of the Royal Society Interface

Volumn 11, Issue 99, 2014, Pages

  Bernabeu, Miguel O ^a   Jones, Martin L ^b   Nielsen, Jens H ^a   Krüger, Timm ^a,c   Nash, Rupert W ^a   Groen, Derek ^a   Schmieschek, Sebastian ^a   Hetherington, James ^a   Gerhardt, Holger ^b   A Franco, Claudio ^b,d   Coveney, Peter V ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b London Research Institute   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

Author keywords

Angiogenesis; Blood flow; Lattice Boltzmann; Mouse; Retina; Shear stress

Indexed keywords

BLOOD VESSELS; COMPLEX NETWORKS; HEMODYNAMICS; MAMMALS; OPHTHALMOLOGY; SHEAR FLOW; SHEAR STRESS;

ANGIOGENESIS; BLOOD FLOW; LATTICE BOLTZMANN; MOUSE; RETINA;

COMPUTER SIMULATION;

TOLL LIKE RECEPTOR ADAPTOR MOLECULE 2;

ALGORITHM; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD FLOWMETRY; BLOOD VESSEL DIAMETER; BLOOD VESSEL WALL; BLOOD VISCOSITY; COMPUTER MODEL; COMPUTER SIMULATION; CONTROLLED STUDY; FEMALE; GEOMETRY; IMAGE PROCESSING; LAMINAR FLOW; MALE; MICROVASCULATURE; MOUSE; NONHUMAN; RETINA ARTERY; RETINA BLOOD FLOW; RETINA BLOOD VESSEL; RETINA VEIN; SENSITIVITY ANALYSIS; SHEAR RATE; SHEAR STRESS; STEADY STATE; THREE DIMENSIONAL IMAGING; VASCULARIZATION; VASODILATATION; ANATOMY AND HISTOLOGY; ANIMAL; BIOLOGICAL MODEL; BIOMECHANICS; CONFOCAL MICROSCOPY; HEMODYNAMICS; PHYSIOLOGY; RETINA;

ANIMALS; BIOMECHANICAL PHENOMENA; COMPUTER SIMULATION; HEMODYNAMICS; IMAGE PROCESSING, COMPUTER-ASSISTED; MICE; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; NEOVASCULARIZATION, PHYSIOLOGIC; RETINA;

EID: 84906998001     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2014.0543     Document Type: Article

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