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Volumn 9, Issue 9, 2014, Pages

FOXP3+lymphocyte density in pancreatic cancer correlates with lymph node metastasis

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER GRADING; CELL DENSITY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FOXP3+ LYMPHOCYTE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; LYMPHOCYTE; LYMPHOCYTIC INFILTRATION; MALE; PANCREAS ADENOCARCINOMA; PANCREAS RESECTION; PANCREATICODUODENECTOMY; RISK FACTOR; CELL COUNT; CYTOLOGY; IMMUNOLOGY; LYMPH NODE; METABOLISM; MIDDLE AGED; PANCREAS TUMOR; PATHOLOGY; PROGNOSIS; REGULATORY T LYMPHOCYTE; YOUNG ADULT;

EID: 84906997513     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106741     Document Type: Article
Times cited : (36)

References (22)
  • 3
    • 84860799288 scopus 로고    scopus 로고
    • Pancreatic ductal adenocarcinoma: A review of immunologic aspects
    • Wachsmann MB, Pop LM, Vitetta ES (2012) Pancreatic ductal adenocarcinoma: a review of immunologic aspects. J Investig Med 60: 643-663.
    • (2012) J Investig Med , vol.60 , pp. 643-663
    • Wachsmann, M.B.1    Pop, L.M.2    Vitetta, E.S.3
  • 4
    • 12244285937 scopus 로고    scopus 로고
    • Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo
    • Chen M-L, Pittet MJ, Gorelik L, Flavell RA, Weissleder R, et al. (2005) Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo. Pro Natl Acad Sci USA 102: 419-424.
    • (2005) Pro Natl Acad Sci USA , vol.102 , pp. 419-424
    • Chen, M.-L.1    Pittet, M.J.2    Gorelik, L.3    Flavell, R.A.4    Weissleder, R.5
  • 5
    • 76049117928 scopus 로고    scopus 로고
    • Elevated expression of Foxp3 in tumor-infiltrating Treg cells suppresses T-cell proliferation and contributes to gastric cancer progression in a COX-2-dependent manner
    • Yuan X-L, Chen L, Li M-X, Dong P, Xue J, et al. (2010) Elevated expression of Foxp3 in tumor-infiltrating Treg cells suppresses T-cell proliferation and contributes to gastric cancer progression in a COX-2-dependent manner. Clin Immunol 134: 277-288.
    • (2010) Clin Immunol , vol.134 , pp. 277-288
    • Yuan, X.-L.1    Chen, L.2    Li, M.-X.3    Dong, P.4    Xue, J.5
  • 6
    • 0041589414 scopus 로고    scopus 로고
    • Human CD4+ CD25+ regulatory T cells suppress NKT cell functions
    • Azuma T, Takahashi T, Kunisato A, Kitamura T, Hirai H (2003) Human CD4+ CD25+ regulatory T cells suppress NKT cell functions. Cancer Res 63: 4516-4520.
    • (2003) Cancer Res , vol.63 , pp. 4516-4520
    • Azuma, T.1    Takahashi, T.2    Kunisato, A.3    Kitamura, T.4    Hirai, H.5
  • 7
    • 44449110691 scopus 로고    scopus 로고
    • Regulatory T cells inhibit dendritic cells by lymphocyte activation gene-3 engagement of MHC class II
    • Liang B, Workman C, Lee J, Chew C, Dale BM, et al. (2008) Regulatory T cells inhibit dendritic cells by lymphocyte activation gene-3 engagement of MHC class II. J Immunol 180: 5916-5926.
    • (2008) J Immunol , vol.180 , pp. 5916-5926
    • Liang, B.1    Workman, C.2    Lee, J.3    Chew, C.4    Dale, B.M.5
  • 8
    • 0036721629 scopus 로고    scopus 로고
    • Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
    • Liyanage UK, Moore TT, Joo H-G, Tanaka Y, Herrmann V, et al. (2002) Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J Immunol 169: 2756-2761.
    • (2002) J Immunol , vol.169 , pp. 2756-2761
    • Liyanage, U.K.1    Moore, T.T.2    Joo, H.-G.3    Tanaka, Y.4    Herrmann, V.5
  • 9
    • 33750630223 scopus 로고    scopus 로고
    • Clinical roles of increased populations of Foxp3+CD4+ T cells in peripheral blood from advanced pancreatic cancer patients
    • Ikemoto T, Yamaguchi T, Morine Y, Imura S, Soejima Y, et al. (2006) Clinical roles of increased populations of Foxp3+CD4+ T cells in peripheral blood from advanced pancreatic cancer patients. Pancreas 33: 386-390.
    • (2006) Pancreas , vol.33 , pp. 386-390
    • Ikemoto, T.1    Yamaguchi, T.2    Morine, Y.3    Imura, S.4    Soejima, Y.5
  • 10
    • 33749317518 scopus 로고    scopus 로고
    • Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions
    • Hiraoka N, Onozato K, Kosuge T, Hirohashi S (2006) Prevalence of FOXP3+ Regulatory T Cells Increases During the Progression of Pancreatic Ductal Adenocarcinoma and Its Premalignant Lesions. Clin Cancer Res 12: 5423-5434.
    • (2006) Clin Cancer Res , vol.12 , pp. 5423-5434
    • Hiraoka, N.1    Onozato, K.2    Kosuge, T.3    Hirohashi, S.4
  • 11
    • 84875228204 scopus 로고    scopus 로고
    • Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer
    • Ino Y, Yamazaki-Itoh R, Shimada K, Iwasaki M, Kosuge T, et al. (2013) Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer. Br J Cancer 108: 914-923.
    • (2013) Br J Cancer , vol.108 , pp. 914-923
    • Ino, Y.1    Yamazaki-Itoh, R.2    Shimada, K.3    Iwasaki, M.4    Kosuge, T.5
  • 12
    • 84898644292 scopus 로고    scopus 로고
    • An increased abundance of tumor-infiltrating regulatory T cells is correlated with the progression and prognosis of pancreatic ductal adenocarcinoma
    • Tang Y, Xu X, Guo S, Zhang C, Tang Y, et al. (2014) An Increased Abundance of Tumor-Infiltrating Regulatory T Cells Is Correlated with the Progression and Prognosis of Pancreatic Ductal Adenocarcinoma. PLoS ONE 9: e91551.
    • (2014) PLoS ONE , vol.9 , pp. e91551
    • Tang, Y.1    Xu, X.2    Guo, S.3    Zhang, C.4    Tang, Y.5
  • 13
    • 84900420880 scopus 로고    scopus 로고
    • Pancreatic ductal adenocarcinoma contains an effector and regulatory immune cell infiltrate that is altered by multimodal neoadjuvant treatment
    • Shibuya KC, Goel VK, Xiong W, Sham JG, Pollack SM, et al. (2014) Pancreatic Ductal Adenocarcinoma Contains an Effector and Regulatory Immune Cell Infiltrate that Is Altered by Multimodal Neoadjuvant Treatment. PLoS ONE 9: e96565.
    • (2014) PLoS ONE , vol.9 , pp. e96565
    • Shibuya, K.C.1    Goel, V.K.2    Xiong, W.3    Sham, J.G.4    Pollack, S.M.5
  • 14
    • 84907003279 scopus 로고    scopus 로고
    • Japanese pancreas society staging systems for pancreatic cancer
    • New York, NY: Springer New York
    • Kondo S (2010) Japanese Pancreas Society Staging Systems for Pancreatic Cancer. Pancreatic Cancer. New York, NY: Springer New York. pp. 1035-1050.
    • (2010) Pancreatic Cancer , pp. 1035-1050
    • Kondo, S.1
  • 15
    • 59649122029 scopus 로고    scopus 로고
    • Pancreatic cancer with paraaortic lymph node metastasis: A contraindication for radical surgery?
    • Yamada S, Nakao A, Fujii T, Sugimoto H, Kanazumi N, et al. (2009) Pancreatic cancer with paraaortic lymph node metastasis: a contraindication for radical surgery? Pancreas 38: e13-e17.
    • (2009) Pancreas , vol.38 , pp. e13-e17
    • Yamada, S.1    Nakao, A.2    Fujii, T.3    Sugimoto, H.4    Kanazumi, N.5
  • 16
    • 19944369145 scopus 로고    scopus 로고
    • Para-aortic lymph node metastasis in carcinoma of the head of the pancreas
    • Sakai M, Nakao A, Kaneko T, Takeda S, Inoue S, et al. (2005) Para-aortic lymph node metastasis in carcinoma of the head of the pancreas. Surgery 137: 606-611.
    • (2005) Surgery , vol.137 , pp. 606-611
    • Sakai, M.1    Nakao, A.2    Kaneko, T.3    Takeda, S.4    Inoue, S.5
  • 17
    • 71549129536 scopus 로고    scopus 로고
    • Prognostic significance of lymph node metastases in pancreatic head cancer treated with extended lymphadenectomy: Not just a matter of numbers
    • Massucco P, Ribero D, Sgotto E, Mellano A, Muratore A, et al. (2009) Prognostic significance of lymph node metastases in pancreatic head cancer treated with extended lymphadenectomy: not just a matter of numbers. Ann Surg Oncol 16: 3323-3332.
    • (2009) Ann Surg Oncol , vol.16 , pp. 3323-3332
    • Massucco, P.1    Ribero, D.2    Sgotto, E.3    Mellano, A.4    Muratore, A.5
  • 18
    • 74049117028 scopus 로고    scopus 로고
    • Evaluation of the prognostic factors and significance of lymph node status in invasive ductal carcinoma of the body or tail of the pancreas
    • Fujita T, Nakagohri T, Gotohda N, Takahashi S, Konishi M, et al. (2010) Evaluation of the prognostic factors and significance of lymph node status in invasive ductal carcinoma of the body or tail of the pancreas. Pancreas 39: e48-e54.
    • (2010) Pancreas , vol.39 , pp. e48-e54
    • Fujita, T.1    Nakagohri, T.2    Gotohda, N.3    Takahashi, S.4    Konishi, M.5
  • 19
    • 84857556564 scopus 로고    scopus 로고
    • Lymphatic and interstitial flow in the tumour microenvironment: Linking mechanobiology with immunity
    • Swartz MA, Lund AW (2012) Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity. Nat Rev Cancer 12: 210-219.
    • (2012) Nat Rev Cancer , vol.12 , pp. 210-219
    • Swartz, M.A.1    Lund, A.W.2
  • 20
    • 77955725489 scopus 로고    scopus 로고
    • Accumulation of Foxp3+ T regulatory cells in draining lymph nodes correlates with disease progression and immune suppression in colorectal cancer patients
    • Deng L, Zhang H, Luan Y, Zhang J, Xing Q, et al. (2010) Accumulation of Foxp3+ T Regulatory Cells in Draining Lymph Nodes Correlates with Disease Progression and Immune Suppression in Colorectal Cancer Patients. Clin Cancer Res 16: 4105-4112.
    • (2010) Clin Cancer Res , vol.16 , pp. 4105-4112
    • Deng, L.1    Zhang, H.2    Luan, Y.3    Zhang, J.4    Xing, Q.5
  • 21
    • 84901361456 scopus 로고    scopus 로고
    • Prognostic value of tumor-infiltrating FoxP3+ T cells in gastrointestinal cancers: A meta analysis
    • Huang Y, Liao H, Zhang Y, Yuan R, Wang F, et al. (2014) Prognostic Value of Tumor-Infiltrating FoxP3+ T Cells in Gastrointestinal Cancers: A Meta Analysis. PLoS ONE 9: e94376.
    • (2014) PLoS ONE , vol.9 , pp. e94376
    • Huang, Y.1    Liao, H.2    Zhang, Y.3    Yuan, R.4    Wang, F.5
  • 22
    • 84886780808 scopus 로고    scopus 로고
    • Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma
    • Obong AE, Clear AJ, Watt J, Wang J, Fatah R, et al. (2013) Activated Pancreatic Stellate Cells Sequester CD8+ T Cells to Reduce Their Infiltration of the Juxtatumoral Compartment of Pancreatic Ductal Adenocarcinoma. Gastroenterology 145: 1121-1132.
    • (2013) Gastroenterology , vol.145 , pp. 1121-1132
    • Obong, A.E.1    Clear, A.J.2    Watt, J.3    Wang, J.4    Fatah, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.