메뉴 건너뛰기




Volumn 37, Issue 9, 2014, Pages 1435-1438

Δ9-Tetrahydrocannabinol targeting estrogen receptor signaling: The possible mechanism of action coupled with endocrine disruption

Author keywords

Anti estrogen; Estrogen receptor; Marijuana; 9 tetrahydrocannabinol

Indexed keywords

CANNABINOID; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABIS; DRONABINOL; ENDOCRINE DISRUPTOR; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; LACTOFERRIN; PESTICIDE; PHYTOESTROGEN; ESTRADIOL; ESTROGEN RECEPTOR ALPHA, HUMAN;

EID: 84906961640     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b14-00226     Document Type: Article
Times cited : (20)

References (43)
  • 1
    • 17344380844 scopus 로고    scopus 로고
    • Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
    • Galve-Roperh I., Sánchez C, Cortés ML, Gómez del Pulgar T, Izquierdo M, Guzmán M. Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nat. Med., 6, 313-319 (2000).
    • (2000) Nat. Med. , vol.6 , pp. 313-319
    • Galve-Roperh, I.1    Sánchez, C.2    Cortés, M.L.3    Gómez Del Pulgar, T.4    Izquierdo, M.5    Guzmán, M.6
  • 5
    • 63149189746 scopus 로고    scopus 로고
    • 9-tetrahydrocannabinol-induced MCF-7 breast cancer cell growth by cyclooxygenase and aromatase
    • 9-tetrahydrocannabinol-induced MCF-7 breast cancer cell growth by cyclooxygenase and aromatase. Toxicology, 259, 25-32 (2009).
    • (2009) Toxicology , vol.259 , pp. 25-32
    • Takeda, S.1    Yamamoto, I.2    Watanabe, K.3
  • 7
    • 79960336157 scopus 로고    scopus 로고
    • The endocannabinoid system and cancer: Therapeutic implication
    • Guindon J, Hohmann AG The endocannabinoid system and cancer: therapeutic implication. Br. J. Pharmacol., 163, 1447-1463 (2011).
    • (2011) Br. J. Pharmacol. , vol.163 , pp. 1447-1463
    • Guindon, J.1    Hohmann, A.G.2
  • 11
    • 84884956810 scopus 로고    scopus 로고
    • Medicinal chemistry and pharmacology focused on can-nabidiol, a major component of the fiber-type cannabis
    • Takeda S. Medicinal chemistry and pharmacology focused on can-nabidiol, a major component of the fiber-type cannabis. Yakugaku Zasshi, 133, 1093-1101 (2013).
    • (2013) Yakugaku Zasshi , vol.133 , pp. 1093-1101
    • Takeda, S.1
  • 12
    • 0021645638 scopus 로고
    • Acute, short-term, and chronic effects of marijuana on the female primate reproductive function
    • Smith CG, Asch RH Acute, short-term, and chronic effects of marijuana on the female primate reproductive function. NIDA Res. Monogr., 44, 82-96 (1984).
    • (1984) NIDA Res. Monogr. , vol.44 , pp. 82-96
    • Smith, C.G.1    Asch, R.H.2
  • 13
    • 0036839387 scopus 로고    scopus 로고
    • Endocrine effects of marijuana
    • Brown TT, Dobs AS Endocrine effects of marijuana. J. Clin. Pharmacol., 42 (Suppl.), 90S-96S (2002).
    • (2002) J. Clin. Pharmacol. , vol.42 , pp. 90S-96S
    • Brown, T.T.1    Dobs, A.S.2
  • 16
    • 0027429548 scopus 로고
    • Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene
    • Lubahn DB, Moyer JS, Golding T.S., Couse JF, Korach KS, Smithies O. Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene. Proc. Natl. Acad. Sci. U.S.A., 90, 11162-11166 (1993).
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 11162-11166
    • Lubahn, D.B.1    Moyer, J.S.2    Golding, T.S.3    Couse, J.F.4    Korach, K.S.5    Smithies, O.6
  • 17
    • 0033305033 scopus 로고    scopus 로고
    • Prevention of the polycystic ovarian phenotype and characterization of ovulatory capacity in the estrogen receptor-α knockout mouse
    • Couse JF, Bunch DO, Lindzey J, Schomberg D.W., Korach KS. Prevention of the polycystic ovarian phenotype and characterization of ovulatory capacity in the estrogen receptor-α knockout mouse. Endocrinology, 140, 5855-5865 (1999).
    • (1999) Endocrinology , vol.140 , pp. 5855-5865
    • Couse, J.F.1    Bunch, D.O.2    Lindzey, J.3    Schomberg, D.W.4    Korach, K.S.5
  • 18
    • 0033767836 scopus 로고    scopus 로고
    • Effect of single and compound knockouts of estrogen receptors α (ERα) and β (ERβ) on mouse reproductive phenotypes
    • Dupont S, Krust A, Gansmuller A., Dierich A, Chambon P, Mark M. Effect of single and compound knockouts of estrogen receptors α (ERα) and β (ERβ) on mouse reproductive phenotypes. Development, 127, 4277-4291 (2000).
    • (2000) Development , vol.127 , pp. 4277-4291
    • Dupont, S.1    Krust, A.2    Gansmuller, A.3    Dierich, A.4    Chambon, P.5    Mark, M.6
  • 20
    • 18844415083 scopus 로고    scopus 로고
    • In vitro growth and ovulation of follicles from ovaries of estrogen receptor (ER)α and ERα null mice indicate a role for ERβ in follicular maturation
    • Emmen JM, Couse JF, Elmore S.A., Yates MM, Kissling GE, Korach KS. In vitro growth and ovulation of follicles from ovaries of estrogen receptor (ER)α and ERα null mice indicate a role for ERβ in follicular maturation. Endocrinology, 146, 2817-2826 (2005).
    • (2005) Endocrinology , vol.146 , pp. 2817-2826
    • Emmen, J.M.1    Couse, J.F.2    Elmore, S.A.3    Yates, M.M.4    Kissling, G.E.5    Korach, K.S.6
  • 21
    • 23044456167 scopus 로고    scopus 로고
    • To β or not to β: Estrogen receptors and ovarian function
    • Woodruff TK, Mayo KE To β or not to β: estrogen receptors and ovarian function. Endocrinology, 146, 3244-3246 (2005).
    • (2005) Endocrinology , vol.146 , pp. 3244-3246
    • Woodruff, T.K.1    Mayo, K.E.2
  • 22
    • 0017660784 scopus 로고
    • 9-tetrahydrocannabinol with estrogen in rat uterine estrogen receptor binding
    • 9-tetrahydrocannabinol with estrogen in rat uterine estrogen receptor binding. Science, 197, 1189-1191 (1977).
    • (1977) Science , vol.197 , pp. 1189-1191
    • Rawitch, A.B.1    Schultz, G.S.2    Ebner, K.E.3    Vardaris, R.M.4
  • 23
    • 0018200066 scopus 로고
    • 9-tetrahydrocannabinol and 17β-estradiol bind to different macromolecules in estrogen target tissues
    • 9-Tetrahydrocannabinol and 17β-estradiol bind to different macromolecules in estrogen target tissues. Science, 200, 312-314 (1978).
    • (1978) Science , vol.200 , pp. 312-314
    • Okey, A.B.1    Bondy, G.P.2
  • 26
    • 0021349496 scopus 로고
    • 1-tetrahydrocannabinol on the steroidogenic activity of rat granulosa cells in culture
    • 1-tetrahydrocannabinol on the steroidogenic activity of rat granulosa cells in culture. Horm. Res., 19, 43-51 (1984).
    • (1984) Horm. Res. , vol.19 , pp. 43-51
    • Lewysohn, O.1    Cordova, T.2    Nimrod, A.3    Ayalon, D.4
  • 30
    • 0033304993 scopus 로고    scopus 로고
    • The estrogen receptor β-isoform (ERβ) of the human estrogen receptor modulates ERα transcriptional activity and is a key regulator of the cellular response to estrogens and anti-estrogens
    • Hall JM, McDonnell DP The estrogen receptor β-isoform (ERβ) of the human estrogen receptor modulates ERα transcriptional activity and is a key regulator of the cellular response to estrogens and anti-estrogens. Endocrinology, 140, 5566-5578 (1999).
    • (1999) Endocrinology , vol.140 , pp. 5566-5578
    • Hall, J.M.1    McDonnell, D.P.2
  • 31
    • 0034641862 scopus 로고    scopus 로고
    • Estrogen receptor β acts as a dominant regulator of estrogen signaling
    • Pettersson K, Delaunay F, Gustafsson JA Estrogen receptor β acts as a dominant regulator of estrogen signaling. Oncogene, 19, 4970-4978 (2000).
    • (2000) Oncogene , vol.19 , pp. 4970-4978
    • Pettersson, K.1    Delaunay, F.2    Gustafsson, J.A.3
  • 33
    • 57749105457 scopus 로고    scopus 로고
    • Intermolecular interactions identify ligand-selective activity of estrogen receptor α/β dimers
    • Powell E, Xu W. Intermolecular interactions identify ligand-selective activity of estrogen receptor α/β dimers. Proc. Natl. Acad. Sci. U.S.A., 105, 19012-19017 (2008).
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 19012-19017
    • Powell, E.1    Xu, W.2
  • 35
    • 0034726057 scopus 로고    scopus 로고
    • Crosstalk between estrogen receptor α and the aryl hydrocarbon receptor in breast cancer cells involves unidirectional activation of proteasomes
    • Wormke M, Stoner M, Saville B., Safe S. Crosstalk between estrogen receptor α and the aryl hydrocarbon receptor in breast cancer cells involves unidirectional activation of proteasomes. FEBS Lett., 478, 109-112 (2000).
    • (2000) FEBS Lett. , vol.478 , pp. 109-112
    • Wormke, M.1    Stoner, M.2    Saville, B.3    Safe, S.4
  • 36
    • 0041307080 scopus 로고    scopus 로고
    • Inhibitory aryl hydrocarbon receptor-estrogen receptor α cross-talk and mechanisms of action
    • Safe S, Wormke M. Inhibitory aryl hydrocarbon receptor-estrogen receptor α cross-talk and mechanisms of action. Chem. Res. Toxicol., 16, 807-816 (2003).
    • (2003) Chem. Res. Toxicol. , vol.16 , pp. 807-816
    • Safe, S.1    Wormke, M.2
  • 37
    • 70349288025 scopus 로고    scopus 로고
    • Dioxin increases the interaction between aryl hydrocarbon receptor and estrogen receptor α at human promoters
    • Ahmed S, Valen E, Sandelin A., Matthews J. Dioxin increases the interaction between aryl hydrocarbon receptor and estrogen receptor α at human promoters. Toxicol. Sci., 111, 254-266 (2009).
    • (2009) Toxicol. Sci. , vol.111 , pp. 254-266
    • Ahmed, S.1    Valen, E.2    Sandelin, A.3    Matthews, J.4
  • 39
  • 40
    • 4944246588 scopus 로고    scopus 로고
    • Loss of ERβ expression as a common step in estrogen-dependent tumor progression
    • Bardin A, Boulle N, Lazennec G., Vignon F, Pujol P. Loss of ERβ expression as a common step in estrogen-dependent tumor progression. Endocr. Relat. Cancer, 11, 537-551 (2004).
    • (2004) Endocr. Relat. Cancer , vol.11 , pp. 537-551
    • Bardin, A.1    Boulle, N.2    Lazennec, G.3    Vignon, F.4    Pujol, P.5
  • 41
    • 29144436510 scopus 로고    scopus 로고
    • Methylation of estrogen receptor β promoter correlates with loss of ER-β expression in mammary carcinoma and is an early indication marker in Premalignant lesions
    • Rody A, Holtrich U, Solbach C., Kourtis K, von Minckwitz G, Engels K, Kissler S., Gätje R, Karn T., Kaufmann M. Methylation of estrogen receptor β promoter correlates with loss of ER-β expression in mammary carcinoma and is an early indication marker in premalignant lesions. Endocr. Relat. Cancer, 12, 903-916 (2005).
    • (2005) Endocr. Relat. Cancer , vol.12 , pp. 903-916
    • Rody, A.1    Holtrich, U.2    Solbach, C.3    Kourtis, K.4    Von Minckwitz, G.5    Engels, K.6    Kissler, S.7    Gätje, R.8    Karn, T.9    Kaufmann, M.10
  • 42
    • 14844362003 scopus 로고    scopus 로고
    • Δ-9-tetrahydro-cannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response
    • McKallip RJ, Nagarkatti M, Nagarkatti PS Δ-9-Tetrahydro-cannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response. J. Immunol., 174, 3281-3289 (2005).
    • (2005) J. Immunol. , vol.174 , pp. 3281-3289
    • McKallip, R.J.1    Nagarkatti, M.2    Nagarkatti, P.S.3
  • 43
    • 0024575997 scopus 로고
    • 1-tetrahydrocannabinol in human fat biopsies from marijuana users by gas chromatography-mass spectrometry
    • 1-tetrahydrocannabinol in human fat biopsies from marijuana users by gas chromatography-mass spectrometry. Biomed. Chromatogr., 3, 35-38 (1989).
    • (1989) Biomed. Chromatogr. , vol.3 , pp. 35-38
    • Johansson, E.1    Norén, K.2    Sjövall, J.3    Halldin, M.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.