-
1
-
-
17344380844
-
Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
-
Galve-Roperh I., Sánchez C, Cortés ML, Gómez del Pulgar T, Izquierdo M, Guzmán M. Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nat. Med., 6, 313-319 (2000).
-
(2000)
Nat. Med.
, vol.6
, pp. 313-319
-
-
Galve-Roperh, I.1
Sánchez, C.2
Cortés, M.L.3
Gómez Del Pulgar, T.4
Izquierdo, M.5
Guzmán, M.6
-
2
-
-
18444376760
-
International union of pharmacology. XXVII. Classification of cannabinoid receptors
-
Howlett AC, Barth F, Bonner T.I., Cabral G., Casellas P, Devane WA, Felder C.C., Herkenham M., Mackie K, Martin BR, Mechoulam R, Pertwee RG International union of pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol. Rev., 54, 161-202 (2002).
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 161-202
-
-
Howlett, A.C.1
Barth, F.2
Bonner, T.I.3
Cabral, G.4
Casellas, P.5
Devane, W.A.6
Felder, C.C.7
Herkenham, M.8
Mackie, K.9
Martin, B.R.10
Mechoulam, R.11
Pertwee, R.G.12
-
3
-
-
33747624175
-
Antitumor activity of plant cannabinoids with emphasis on the effect of can-nabidiol on human breast carcinoma
-
Ligresti A, Moriello AS, Starowicz K, Matias I., Pisanti S, De Petrocellis L, Laezza C, Portella G, Bifulco M, Di Marzo V. Antitumor activity of plant cannabinoids with emphasis on the effect of can-nabidiol on human breast carcinoma. J. Pharmacol. Exp. Ther., 318, 1375-1387 (2006).
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.318
, pp. 1375-1387
-
-
Ligresti, A.1
Moriello, A.S.2
Starowicz, K.3
Matias, I.4
Pisanti, S.5
De Petrocellis, L.6
Laezza, C.7
Portella, G.8
Bifulco, M.9
Di Marzo, V.10
-
4
-
-
39249083222
-
9-tetrahydrocannabinol enhances MCF-7 cell proliferation via cannabinoid receptor-independent signaling
-
9-Tetrahydrocannabinol enhances MCF-7 cell proliferation via cannabinoid receptor-independent signaling. Toxicology, 245, 141-146 (2008).
-
(2008)
Toxicology
, vol.245
, pp. 141-146
-
-
Takeda, S.1
Yamaori, S.2
Motoya, E.3
Matsunaga, T.4
Kimura, T.5
Yama-Moto, I.6
Watanabe, K.7
-
5
-
-
63149189746
-
9-tetrahydrocannabinol-induced MCF-7 breast cancer cell growth by cyclooxygenase and aromatase
-
9-tetrahydrocannabinol-induced MCF-7 breast cancer cell growth by cyclooxygenase and aromatase. Toxicology, 259, 25-32 (2009).
-
(2009)
Toxicology
, vol.259
, pp. 25-32
-
-
Takeda, S.1
Yamamoto, I.2
Watanabe, K.3
-
6
-
-
78650120798
-
2
-
2. Pharmacol. Rev., 62, 588-631 (2010).
-
(2010)
Pharmacol. Rev.
, vol.62
, pp. 588-631
-
-
Pertwee, R.G.1
Howlett, A.C.2
Abood, M.E.3
Alexander, S.P.4
Di Marzo, V.5
Elphick, M.R.6
Greasley, P.J.7
Hansen, H.S.8
Kunos, G.9
Mackie, K.10
Mechoulam, R.11
Ross, R.A.12
-
7
-
-
79960336157
-
The endocannabinoid system and cancer: Therapeutic implication
-
Guindon J, Hohmann AG The endocannabinoid system and cancer: therapeutic implication. Br. J. Pharmacol., 163, 1447-1463 (2011).
-
(2011)
Br. J. Pharmacol.
, vol.163
, pp. 1447-1463
-
-
Guindon, J.1
Hohmann, A.G.2
-
8
-
-
79251544250
-
9-tetrahydrocannabinol-11-oic acid as 15-lipoxy-genase inhibitors
-
9-tetrahydrocannabinol-11-oic acid as 15-lipoxy-genase inhibitors. J. Pharm. Sci., 100, 1206-1211 (2011).
-
(2011)
J. Pharm. Sci.
, vol.100
, pp. 1206-1211
-
-
Takeda, S.1
Jiang, R.2
Aramaki, H.3
Imoto, M.4
Toda, A.5
Eyanagi, R.6
Ama-Moto, T.7
Yamamoto, I.8
Watanabe, K.9
-
9
-
-
84875487849
-
9-tetrahydrocannabinol in human breast cancer cells
-
9-tetrahydrocannabinol in human breast cancer cells. J. Toxi col. Sci., 38, 305-308 (2013).
-
(2013)
J. Toxi Col. Sci.
, vol.38
, pp. 305-308
-
-
Takeda, S.1
Harada, M.2
Su, S.3
Okajima, S.4
Miyoshi, H.5
Yoshida, K.6
Nishimura, H.7
Okamoto, Y.8
Amamoto, T.9
Watanabe, K.10
Omiecinski, C.J.11
Aramaki, H.12
-
10
-
-
84880291490
-
9-tetrahydrocannabinol disrupts estrogen-signaling through up-regulation of estrogen receptor β (ERβ)
-
9-Tetrahydrocannabinol disrupts estrogen-signaling through up-regulation of estrogen receptor β (ERβ). Chem. Res. Toxicol., 26, 1073-1079 (2013).
-
(2013)
Chem. Res. Toxicol.
, vol.26
, pp. 1073-1079
-
-
Takeda, S.1
Yoshida, K.2
Nishimura, H.3
Harada, M.4
Okajima, S.5
Miyoshi, H.6
Okamoto, Y.7
Amamoto, T.8
Watanabe, K.9
Omiecinski, C.J.10
Aramaki, H.11
-
11
-
-
84884956810
-
Medicinal chemistry and pharmacology focused on can-nabidiol, a major component of the fiber-type cannabis
-
Takeda S. Medicinal chemistry and pharmacology focused on can-nabidiol, a major component of the fiber-type cannabis. Yakugaku Zasshi, 133, 1093-1101 (2013).
-
(2013)
Yakugaku Zasshi
, vol.133
, pp. 1093-1101
-
-
Takeda, S.1
-
12
-
-
0021645638
-
Acute, short-term, and chronic effects of marijuana on the female primate reproductive function
-
Smith CG, Asch RH Acute, short-term, and chronic effects of marijuana on the female primate reproductive function. NIDA Res. Monogr., 44, 82-96 (1984).
-
(1984)
NIDA Res. Monogr.
, vol.44
, pp. 82-96
-
-
Smith, C.G.1
Asch, R.H.2
-
13
-
-
0036839387
-
Endocrine effects of marijuana
-
Brown TT, Dobs AS Endocrine effects of marijuana. J. Clin. Pharmacol., 42 (Suppl.), 90S-96S (2002).
-
(2002)
J. Clin. Pharmacol.
, vol.42
, pp. 90S-96S
-
-
Brown, T.T.1
Dobs, A.S.2
-
16
-
-
0027429548
-
Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene
-
Lubahn DB, Moyer JS, Golding T.S., Couse JF, Korach KS, Smithies O. Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene. Proc. Natl. Acad. Sci. U.S.A., 90, 11162-11166 (1993).
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 11162-11166
-
-
Lubahn, D.B.1
Moyer, J.S.2
Golding, T.S.3
Couse, J.F.4
Korach, K.S.5
Smithies, O.6
-
17
-
-
0033305033
-
Prevention of the polycystic ovarian phenotype and characterization of ovulatory capacity in the estrogen receptor-α knockout mouse
-
Couse JF, Bunch DO, Lindzey J, Schomberg D.W., Korach KS. Prevention of the polycystic ovarian phenotype and characterization of ovulatory capacity in the estrogen receptor-α knockout mouse. Endocrinology, 140, 5855-5865 (1999).
-
(1999)
Endocrinology
, vol.140
, pp. 5855-5865
-
-
Couse, J.F.1
Bunch, D.O.2
Lindzey, J.3
Schomberg, D.W.4
Korach, K.S.5
-
18
-
-
0033767836
-
Effect of single and compound knockouts of estrogen receptors α (ERα) and β (ERβ) on mouse reproductive phenotypes
-
Dupont S, Krust A, Gansmuller A., Dierich A, Chambon P, Mark M. Effect of single and compound knockouts of estrogen receptors α (ERα) and β (ERβ) on mouse reproductive phenotypes. Development, 127, 4277-4291 (2000).
-
(2000)
Development
, vol.127
, pp. 4277-4291
-
-
Dupont, S.1
Krust, A.2
Gansmuller, A.3
Dierich, A.4
Chambon, P.5
Mark, M.6
-
19
-
-
0034602787
-
Estrogen receptors α and β in the rodent mammary gland
-
Saji S, Jensen EV, Nilsson S, Rylander T., Warner M, Gustafsson JA. Estrogen receptors α and β in the rodent mammary gland. Proc. Natl. Acad. Sci. U.S.A., 97, 337-342 (2000).
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 337-342
-
-
Saji, S.1
Jensen, E.V.2
Nilsson, S.3
Rylander, T.4
Warner, M.5
Gustafsson, J.A.6
-
20
-
-
18844415083
-
In vitro growth and ovulation of follicles from ovaries of estrogen receptor (ER)α and ERα null mice indicate a role for ERβ in follicular maturation
-
Emmen JM, Couse JF, Elmore S.A., Yates MM, Kissling GE, Korach KS. In vitro growth and ovulation of follicles from ovaries of estrogen receptor (ER)α and ERα null mice indicate a role for ERβ in follicular maturation. Endocrinology, 146, 2817-2826 (2005).
-
(2005)
Endocrinology
, vol.146
, pp. 2817-2826
-
-
Emmen, J.M.1
Couse, J.F.2
Elmore, S.A.3
Yates, M.M.4
Kissling, G.E.5
Korach, K.S.6
-
21
-
-
23044456167
-
To β or not to β: Estrogen receptors and ovarian function
-
Woodruff TK, Mayo KE To β or not to β: estrogen receptors and ovarian function. Endocrinology, 146, 3244-3246 (2005).
-
(2005)
Endocrinology
, vol.146
, pp. 3244-3246
-
-
Woodruff, T.K.1
Mayo, K.E.2
-
23
-
-
0018200066
-
9-tetrahydrocannabinol and 17β-estradiol bind to different macromolecules in estrogen target tissues
-
9-Tetrahydrocannabinol and 17β-estradiol bind to different macromolecules in estrogen target tissues. Science, 200, 312-314 (1978).
-
(1978)
Science
, vol.200
, pp. 312-314
-
-
Okey, A.B.1
Bondy, G.P.2
-
24
-
-
0020697089
-
Marijuana: Interaction with the estrogen receptor
-
Sauer MA, Rifka SM, Hawks R.L., Cutler GB Jr, Loriaux DL. Marijuana: interaction with the estrogen receptor. J. Pharmacol. Exp. Ther., 224, 404-407 (1983).
-
(1983)
J. Pharmacol. Exp. Ther.
, vol.224
, pp. 404-407
-
-
Sauer, M.A.1
Rifka, S.M.2
Hawks, R.L.3
Cutler, G.B.4
Loriaux, D.L.5
-
25
-
-
0031060674
-
Failure of cannabi-noid compounds to stimulate estrogen receptors
-
Ruh MF, Taylor JA, Howlett A.C., Welshons W V. Failure of cannabi-noid compounds to stimulate estrogen receptors. Biochem. Pharmacol., 53, 35-41 (1997).
-
(1997)
Biochem. Pharmacol.
, vol.53
, pp. 35-41
-
-
Ruh, M.F.1
Taylor, J.A.2
Howlett, A.C.3
Welshons, W.V.4
-
26
-
-
0021349496
-
1-tetrahydrocannabinol on the steroidogenic activity of rat granulosa cells in culture
-
1-tetrahydrocannabinol on the steroidogenic activity of rat granulosa cells in culture. Horm. Res., 19, 43-51 (1984).
-
(1984)
Horm. Res.
, vol.19
, pp. 43-51
-
-
Lewysohn, O.1
Cordova, T.2
Nimrod, A.3
Ayalon, D.4
-
27
-
-
0030579801
-
Cloning of a novel receptor expressed in rat prostate and ovary
-
Kuiper GG, Enmark E, Pelto-Huikko M, Nilsson S., Gustafsson JA. Cloning of a novel receptor expressed in rat prostate and ovary. Proc. Natl. Acad. Sci. U.S.A., 93, 5925-5930 (1996).
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 5925-5930
-
-
Kuiper, G.G.1
Enmark, E.2
Pelto-Huikko, M.3
Nilsson, S.4
Gustafsson, J.A.5
-
28
-
-
0029074489
-
Cannabinoid ligand-re-ceptor signaling in the mouse uterus
-
Das SK, Paria BC, Chakraborty I, Dey SK Cannabinoid ligand-re-ceptor signaling in the mouse uterus. Proc. Natl. Acad. Sci. U.S.A., 92, 4332-4336 (1995).
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 4332-4336
-
-
Das, S.K.1
Paria, B.C.2
Chakraborty, I.3
Dey, S.K.4
-
29
-
-
0034705032
-
Estrogen receptor (ER) β, a modulator of ERα in the uterus
-
Weihua Z, Saji S, Mäkinen S, Cheng G., Jensen EV, Warner M, Gustafsson JA. Estrogen receptor (ER) β, a modulator of ERα in the uterus. Proc. Natl. Acad. Sci. U.S.A., 97, 5936-5941 (2000).
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 5936-5941
-
-
Weihua, Z.1
Saji, S.2
Mäkinen, S.3
Cheng, G.4
Jensen, E.V.5
Warner, M.6
Gustafsson, J.A.7
-
30
-
-
0033304993
-
The estrogen receptor β-isoform (ERβ) of the human estrogen receptor modulates ERα transcriptional activity and is a key regulator of the cellular response to estrogens and anti-estrogens
-
Hall JM, McDonnell DP The estrogen receptor β-isoform (ERβ) of the human estrogen receptor modulates ERα transcriptional activity and is a key regulator of the cellular response to estrogens and anti-estrogens. Endocrinology, 140, 5566-5578 (1999).
-
(1999)
Endocrinology
, vol.140
, pp. 5566-5578
-
-
Hall, J.M.1
McDonnell, D.P.2
-
31
-
-
0034641862
-
Estrogen receptor β acts as a dominant regulator of estrogen signaling
-
Pettersson K, Delaunay F, Gustafsson JA Estrogen receptor β acts as a dominant regulator of estrogen signaling. Oncogene, 19, 4970-4978 (2000).
-
(2000)
Oncogene
, vol.19
, pp. 4970-4978
-
-
Pettersson, K.1
Delaunay, F.2
Gustafsson, J.A.3
-
32
-
-
34248586255
-
Estrogen receptor β2 negatively regulates the transactivation of estrogen receptor α in human breast cancer cells
-
Zhao C, Matthews J, Tujague M., Wan J, Ström A, Toresson G., Lam EW, Cheng G, Gustafsson JA, Dahlman-Wright K. Estrogen receptor β2 negatively regulates the transactivation of estrogen receptor α in human breast cancer cells. Cancer Res., 67, 3955-3962 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 3955-3962
-
-
Zhao, C.1
Matthews, J.2
Tujague, M.3
Wan, J.4
Ström, A.5
Toresson, G.6
Lam, E.W.7
Cheng, G.8
Gustafsson, J.A.9
Dahlman-Wright, K.10
-
33
-
-
57749105457
-
Intermolecular interactions identify ligand-selective activity of estrogen receptor α/β dimers
-
Powell E, Xu W. Intermolecular interactions identify ligand-selective activity of estrogen receptor α/β dimers. Proc. Natl. Acad. Sci. U.S.A., 105, 19012-19017 (2008).
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 19012-19017
-
-
Powell, E.1
Xu, W.2
-
34
-
-
42949142113
-
The aryl hydrocarbon receptor complex and the control of gene expression
-
Beischlag TV, Luis Morales J, Hollingshead BD, Perdew GH The aryl hydrocarbon receptor complex and the control of gene expression. Crit. Rev. Eukaryot. Gene Expr., 18, 207-250 (2008).
-
(2008)
Crit. Rev. Eukaryot. Gene Expr.
, vol.18
, pp. 207-250
-
-
Beischlag, T.V.1
Luis Morales, J.2
Hollingshead, B.D.3
Perdew, G.H.4
-
35
-
-
0034726057
-
Crosstalk between estrogen receptor α and the aryl hydrocarbon receptor in breast cancer cells involves unidirectional activation of proteasomes
-
Wormke M, Stoner M, Saville B., Safe S. Crosstalk between estrogen receptor α and the aryl hydrocarbon receptor in breast cancer cells involves unidirectional activation of proteasomes. FEBS Lett., 478, 109-112 (2000).
-
(2000)
FEBS Lett.
, vol.478
, pp. 109-112
-
-
Wormke, M.1
Stoner, M.2
Saville, B.3
Safe, S.4
-
36
-
-
0041307080
-
Inhibitory aryl hydrocarbon receptor-estrogen receptor α cross-talk and mechanisms of action
-
Safe S, Wormke M. Inhibitory aryl hydrocarbon receptor-estrogen receptor α cross-talk and mechanisms of action. Chem. Res. Toxicol., 16, 807-816 (2003).
-
(2003)
Chem. Res. Toxicol.
, vol.16
, pp. 807-816
-
-
Safe, S.1
Wormke, M.2
-
37
-
-
70349288025
-
Dioxin increases the interaction between aryl hydrocarbon receptor and estrogen receptor α at human promoters
-
Ahmed S, Valen E, Sandelin A., Matthews J. Dioxin increases the interaction between aryl hydrocarbon receptor and estrogen receptor α at human promoters. Toxicol. Sci., 111, 254-266 (2009).
-
(2009)
Toxicol. Sci.
, vol.111
, pp. 254-266
-
-
Ahmed, S.1
Valen, E.2
Sandelin, A.3
Matthews, J.4
-
38
-
-
0035095986
-
9-tetrahydrocannabinol
-
9-tetrahydrocannabinol. Am. J. Respir. Cell Mol. Biol., 24, 339-344 (2001).
-
(2001)
Am. J. Respir. Cell Mol. Biol.
, vol.24
, pp. 339-344
-
-
Roth, M.D.1
Marques-Magallanes, J.A.2
Yuan, M.3
Sun, W.4
Tashkin, D.P.5
Hankinson, O.6
-
39
-
-
0344873122
-
Expression of estrogen receptor β isoforms in normal breast epithelial cells and breast cancer: Regulation by methylation
-
Zhao C, Lam EW, Sunters A, Enmark E., De Bella MT, Coombes RC, Gustafsson JA, Dahlman-Wright K. Expression of estrogen receptor β isoforms in normal breast epithelial cells and breast cancer: regulation by methylation. Oncogene, 22, 7600-7606 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 7600-7606
-
-
Zhao, C.1
Lam, E.W.2
Sunters, A.3
Enmark, E.4
De Bella, M.T.5
Coombes, R.C.6
Gustafsson, J.A.7
Dahlman-Wright, K.8
-
40
-
-
4944246588
-
Loss of ERβ expression as a common step in estrogen-dependent tumor progression
-
Bardin A, Boulle N, Lazennec G., Vignon F, Pujol P. Loss of ERβ expression as a common step in estrogen-dependent tumor progression. Endocr. Relat. Cancer, 11, 537-551 (2004).
-
(2004)
Endocr. Relat. Cancer
, vol.11
, pp. 537-551
-
-
Bardin, A.1
Boulle, N.2
Lazennec, G.3
Vignon, F.4
Pujol, P.5
-
41
-
-
29144436510
-
Methylation of estrogen receptor β promoter correlates with loss of ER-β expression in mammary carcinoma and is an early indication marker in Premalignant lesions
-
Rody A, Holtrich U, Solbach C., Kourtis K, von Minckwitz G, Engels K, Kissler S., Gätje R, Karn T., Kaufmann M. Methylation of estrogen receptor β promoter correlates with loss of ER-β expression in mammary carcinoma and is an early indication marker in premalignant lesions. Endocr. Relat. Cancer, 12, 903-916 (2005).
-
(2005)
Endocr. Relat. Cancer
, vol.12
, pp. 903-916
-
-
Rody, A.1
Holtrich, U.2
Solbach, C.3
Kourtis, K.4
Von Minckwitz, G.5
Engels, K.6
Kissler, S.7
Gätje, R.8
Karn, T.9
Kaufmann, M.10
-
42
-
-
14844362003
-
Δ-9-tetrahydro-cannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response
-
McKallip RJ, Nagarkatti M, Nagarkatti PS Δ-9-Tetrahydro-cannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response. J. Immunol., 174, 3281-3289 (2005).
-
(2005)
J. Immunol.
, vol.174
, pp. 3281-3289
-
-
McKallip, R.J.1
Nagarkatti, M.2
Nagarkatti, P.S.3
-
43
-
-
0024575997
-
1-tetrahydrocannabinol in human fat biopsies from marijuana users by gas chromatography-mass spectrometry
-
1-tetrahydrocannabinol in human fat biopsies from marijuana users by gas chromatography-mass spectrometry. Biomed. Chromatogr., 3, 35-38 (1989).
-
(1989)
Biomed. Chromatogr.
, vol.3
, pp. 35-38
-
-
Johansson, E.1
Norén, K.2
Sjövall, J.3
Halldin, M.M.4
|