Intestinal cell kinase is a novel participant in intestinal cell signaling responses to protein malnutrition

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Bolick, David T ^a   Chen, Tufeng ^a,b   Alves, Luís Antonio O ^a   Tong, Yixin ^a,c   Wu, Di ^a   Joyner, Linwood T ^a   Oriá, Reinaldo B ^a   Guerrant, Richard L ^a   Fu, Zheng ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

INTESTINAL CELL KINASE; INTESTINE ENZYME; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; WNT PROTEIN; ICK PROTEIN, HUMAN; ICK PROTEIN, MOUSE; MTOR PROTEIN, HUMAN; MTOR PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; ILEOCECAL VALVE; IN VITRO STUDY; INTESTINE ADAPTATION; INTESTINE CELL; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CELL LINE; ENZYMOLOGY; INTESTINE MUCOSA; METABOLISM; PATHOLOGY; WNT SIGNALING PATHWAY;

ANIMALS; CELL LINE; CELL SURVIVAL; HUMANS; INTESTINAL MUCOSA; MICE; PROTEIN DEFICIENCY; PROTEIN-SERINE-THREONINE KINASES; TOR SERINE-THREONINE KINASES; WNT SIGNALING PATHWAY;

EID: 84906958513     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106902     Document Type: Article

References (33)

1. Jenkins AP, Thompson RP (1994) Enteral nutrition and the small intestine. Gut 35: 1765-1769.
2. Johnson LR (1988) Regulation of gastrointestinal mucosal growth. Physiol Rev 68: 456-502.
3. Raul F, Schleiffer R (1996) Intestinal adaptation to nutritional stress. Proc Nutr Soc 55: 279-289.
4. Drozdowski L, Thomson AB (2006) Intestinal mucosal adaptation. World J - Gastroenterol 12: 4614-4627.
5. Pinto D, Gregorieff A, Begthel H, Clevers H (2003) Canonical Wnt signals are essential for homeostasis of the intestinal epithelium. Genes Dev 17: 1709-1713.
6. Sheng H, Shao J, Townsend CM, Jr., Evers BM (2003) Phosphatidylinositol 3-kinase mediates proliferative signals in intestinal epithelial cells. Gut 52: 1472-1478.
7. Yilmaz OH, Katajisto P, Lamming DW, Gultekin Y, Bauer-Rowe KE, et al. (2012) mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake. Nature 486: 490-495.
8. Aliaga JC, Deschenes C, Beaulieu JF, Calvo EL, Rivard N (1999) Requirement of the MAP kinase cascade for cell cycle progression and differentiation of human intestinal cells. Am J Physiol 277: G631-641.
9. Togawa K, Yan YX, Inomoto T, Slaugenhaupt S, Rustgi AK (2000) Intestinal cell kinase (ICK) localizes to the crypt region and requires a dual phosphorylation site found in map kinases. J Cell Physiol 183: 129-139.
10. Fu Z, Kim J, Vidrich A, Sturgill TW, Cohn SM (2009) Intestinal cell kinase, a MAP kinase-related kinase, regulates proliferation and G1 cell cycle progression of intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 297: G632-640.
11. Fu Z, Larson KA, Chitta RK, Parker SA, Turk BE, et al. (2006) Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase. Mol Cell Biol 26: 8639-8654.
12. Fu Z, Schroeder MJ, Shabanowitz J, Kaldis P, Togawa K, et al. (2005) Activation of a nuclear Cdc2-related kinase within a mitogen-activated protein kinase-like TDY motif by autophosphorylation and cyclin-dependent protein kinase-activating kinase. Mol Cell Biol 25: 6047-6064.
13. Liu Y, Wu C, Galaktionov K (2004) p42, a novel cyclin-dependent kinase-activating kinase in mammalian cells. J Biol Chem 279: 4507-4514.
14. An X, Ng SS, Xie D, Zeng YX, Sze J, et al. (2010) Functional characterisation of cell cycle-related kinase (CCRK) in colorectal cancer carcinogenesis. Eur - J Cancer 46: 1752-1761.
15. Tompkins WA, Watrach AM, Schmale JD, Schultz RM, Harris JA (1974) Cultural and antigenic properties of newly established cell strains derived from adenocarcinomas of the human colon and rectum. J Natl Cancer Inst 52: 1101-1110.
16. Chen T, Wu D, Moskaluk CA, Fu Z (2013) Distinct expression patterns of ICK/MAK/MOK protein kinases in the intestine implicate functional diversity. PLoS One 8: e79359.
17. Costa LB, JohnBull EA, Reeves JT, Sevilleja JE, Freire RS, et al. (2011) Cryptosporidium-malnutrition interactions: mucosal disruption, cytokines, and TLR signaling in a weaned murine model. J Parasitol 97: 1113-1120.
18. Manning BD, Cantley LC (2007) AKT/PKB signaling: navigating downstream. Cell 129: 1261-1274.
19. Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, et al. (2007) Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449: 1003-1007.
20. Sangiorgi E, Capecchi MR (2008) Bmi1 is expressed in vivo in intestinal stem cells. Nat Genet 40: 915-920.
21. Costa LB, Noronha FJ, Roche JK, Sevilleja JE, Warren CA, et al. (2012) Novel in vitro and in vivo models and potential new therapeutics to break the vicious cycle of Cryptosporidium infection and malnutrition. J Infect Dis 205: 1464-1471.
22. Nicholson JP, Wolmarans MR, Park GR (2000) The role of albumin in critical illness. Br J Anaesth 85: 599-610.
23. Tappenden KA (2006) Mechanisms of enteral nutrient-enhanced intestinal adaptation. Gastroenterology 130: S93-99.
24. Lipkin M, Quastler H (1962) Studies of protein metabolism in intestinal epithelial cells. J Clin Invest 41: 646-653.
25. Hill RB, Jr., Prosper J, Hirschfield JS, Kern F, Jr. (1968) Protein starvation and the small intestine. I. The growth and morphology of the small intestine in weanling rats. Exp Mol Pathol 8: 66-74.
26. Sokolovic M, Wehkamp D, Sokolovic A, Vermeulen J, Gilhuijs-Pederson LA, et al. (2007) Fasting induces a biphasic adaptive metabolic response in murine small intestine. BMC Genomics 8: 361.
27. Chappell VL, Thompson MD, Jeschke MG, Chung DH, Thompson JC, et al. (2003) Effects of incremental starvation on gut mucosa. Dig Dis Sci 48: 765-769.
28. Coutinho BP, Oria RB, Vieira CM, Sevilleja JE, Warren CA, et al. (2008) Cryptosporidium infection causes undernutrition and, conversely, weanling undernutrition intensifies infection. J Parasitol 94: 1225-1232.
29. Deo MG, Ramalingaswami V (1965) Reaction of the Small Intestine to Induced Protein Malnutrition in Rhesus Monkeys. A Study of Cell Population Kinetics in the Jejunum. Gastroenterology 49: 150-157.
30. Hooper CS, Blair M (1958) The effect of starvation on epithelial renewal in the rat duodenum. Exp Cell Res 14: 175-181.
31. Muramatsu K, Sato T, Ashida K (1963) Dietary Protein Level and the Turnover Rate of Tissue Proteins in Rats. J Nutr 81: 427-433.
32. Sturgill TW, Stoddard PB, Cohn SM, Mayo MW (2010) The promoter for intestinal cell kinase is head-to-head with F-Box 9 and contains functional sites for TCF7L2 and FOXA factors. Mol Cancer 9: 104.
33. Lee KW, Kwak SH, Ahn BY, Lee HM, Jung HS, et al. (2013) F-box only protein 9 is required for adipocyte differentiation. Biochem Biophys Res Commun 435: 239-243.