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Angewandte Chemie - International Edition

Volumn 53, Issue 36, 2014, Pages 9471-9475

Using the population-shift mechanism to rationally introduce "hill-type" cooperativity into a normally non-cooperative receptor

(5) Simon, Anna J a Vallée Bélisle, Alexis b Ricci, Francesco c Watkins, Herschel M a,d Plaxco, Kevin W a

a UNIVERSITY OF CALIFORNIA (United States)

b UNIVERSITÉ DE MONTRÉAL (Canada)

c UNIVERSITY OF ROME TOR VERGATA (Italy)

d STANFORD UNIVERSITY (United States)

Author keywords

allosterism; cooperative effects; DNA; sensors; synthetic biology

Indexed keywords

BINDING SITES; BIOSENSORS; DNA; ENGINEERS; LIGANDS; SENSORS;

ALLOSTERISM; CO-OPERATIVE EFFECTS; LIGAND CONCENTRATION; MOLECULAR BEACON; RATIONAL DESIGN; RESPONSIVE MATERIALS; SHIFT MECHANISM; USEFUL PROPERTIES;

SYNTHETIC BIOLOGY;

BIOMATERIAL; DNA; DRUG RECEPTOR; LIGAND;

BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECTS; GENETIC PROCEDURES; PROTEIN ENGINEERING;

BINDING SITES; BIOCOMPATIBLE MATERIALS; BIOSENSING TECHNIQUES; DNA; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEIN ENGINEERING; RECEPTORS, DRUG;

EID: 84906947812 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201403777 Document Type: Article

Times cited : (41)

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