Rational design of allosteric inhibitors and activators using the population-shift model: In vitro validation and application to an artificial biosensor

Journal of the American Chemical Society

Volumn 134, Issue 37, 2012, Pages 15177-15180

  Ricci, Francesco ^a,b   Vallée Bélisle, Alexis ^c,d   Porchetta, Alessandro ^a,b   Plaxco, Kevin W ^c  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b NATIONAL INSTITUTE OF BIOSTRUCTURES AND BIOSYSTEMS   (Italy)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC INHIBITION; ALLOSTERIC INHIBITOR; ALLOSTERIC REGULATION; ALLOSTERIC SITE; IN-VITRO; MOLECULAR BEACON; ORDERS OF MAGNITUDE; PROOF OF PRINCIPLES; RATIONAL DESIGN;

BIOLOGICAL MATERIALS;

BIOSENSORS;

BIOMATERIAL;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BIOSENSOR; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; VALIDATION PROCESS;

ALLOSTERIC SITE; BIOSENSING TECHNIQUES; MODELS, THEORETICAL;

EID: 84866521002     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja304672h     Document Type: Article

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