An amphipathic alpha-helical peptide from apolipoprotein A1 stabilizes protein polymer vesicles

Journal of Controlled Release

Volumn 191, Issue , 2014, Pages 15-23

  Pastuszka, Martha K ^a   Wang, Xiangdong ^b   Lock, Lye Lin ^c   Janib, Siti Mohd ^a   Cui, Honggang ^c   Deleve, Laurie D ^b   MacKay, J Andrew ^a,d  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c Johns Hopkins University   (United States)

^d University of Southern California   (United States)

Author keywords

Cryo TEM; Elastin like polypeptide; Hydrodynamic radius; L 4F; Nanoparticle; Vesicle

Indexed keywords

BIOACTIVITY; BIODEGRADABLE POLYMERS; BIOMIMETICS; CHEMICAL ACTIVATION; ELASTIN; FLUID DYNAMICS; GLYCOPROTEINS; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; HYDRODYNAMICS; LIGHT SCATTERING; NANOPARTICLES; PEPTIDES; POLYMERS; POLYPEPTIDES; PROTEINS; STABILIZATION; TRANSMISSION ELECTRON MICROSCOPY;

ANTI-OXIDANT ACTIVITIES; CARDIO-VASCULAR DISEASE; CRYO-TEM; CRYOGENIC TRANSMISSION ELECTRON MICROSCOPY; ELASTIN-LIKE POLYPEPTIDES; HIGH MOLECULAR WEIGHT PROTEIN; HYDRODYNAMIC RADIUS; VESICLE;

NANOSTRUCTURES;

AMPHIPATHIC L4F PEPTIDE; APOLIPOPROTEIN A1; NANOPARTICLE; POLYMER; POLYPEPTIDE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; DRUG CARRIER; HYBRID PROTEIN; PEPTIDE FRAGMENT; TROPOELASTIN;

ALPHA HELIX; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; HYDRODYNAMICS; LIGHT SCATTERING; MORPHOLOGY; MOUSE; NONHUMAN; PLASMA CLEARANCE; PLASMA HALF LIFE; PRIORITY JOURNAL; PROTEIN STABILITY; STELLATE CELL; TRANSMISSION ELECTRON MICROSCOPY; VOLUME OF DISTRIBUTION; ANIMAL; BLOOD; CELL CULTURE; CHEMISTRY; DRUG EFFECTS; GENETIC ENGINEERING; GENETICS; HALF LIFE TIME; INTRAVENOUS DRUG ADMINISTRATION; MEDICINAL CHEMISTRY; METABOLISM; NANOTECHNOLOGY; PARTICLE SIZE; PHARMACEUTICS; PROCEDURES; PROTEIN SECONDARY STRUCTURE; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; APOLIPOPROTEIN A-I; CELLS, CULTURED; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; GENETIC ENGINEERING; HALF-LIFE; HEPATIC STELLATE CELLS; INJECTIONS, INTRAVENOUS; MICE; NANOPARTICLES; NANOTECHNOLOGY; PARTICLE SIZE; PEPTIDE FRAGMENTS; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; RATS; RECOMBINANT FUSION PROTEINS; TECHNOLOGY, PHARMACEUTICAL; TROPOELASTIN;

EID: 84906947802     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.07.003     Document Type: Article

References (39)

1. W. Rathmann, G. Giani, Global prevalence of diabetes: estimates for the year 2000 and projections for 2030, Diabetes Care 27 (2004) 2568-2569 (author reply 2569).
2. S.L. Friedman, Liver fibrosis - frombench to bedside, J. Hepatol. 38 (Suppl. 1) (2003) S38-S53.
3. L.D. DeLeve, X.Wang, G.C. Kanel, R.D. Atkinson, R.S.McCuskey, Prevention of hepatic fibrosis in amurinemodel ofmetabolic syndromewith nonalcoholic steatohepatitis, Am. J. Pathol. 173 (2008) 993-1001.
4. D.W. Garber, Y.V. Venkatachalapathi, K.B. Gupta, J. Ibdah, M.C. Phillips, J.B. Hazelrig, J. P. Segrest, G.M. Anantharamaiah, Turnover of synthetic class A amphipathic peptide analogues of exchangeable apolipoproteins in rats. Correlation with physical properties, Arterioscler. Thromb. 12 (1992) 886-894.
5. K. Hristova, W.C.Wimley, V.K. Mishra, G.M. Anantharamiah, J.P. Segrest, S.H.White, An amphipathic alpha-helix at a membrane interface: A structural study using a novel X-ray diffraction method, J. Mol. Biol. 290 (1999) 99-117.
6. A.J. Mendez, G.M. Anantharamaiah, J.P. Segrest, J.F. Oram, Synthetic amphipathic helical peptides that mimic apolipoprotein A-I in clearing cellular cholesterol, J. Clin. Invest. 94 (1994) 1698-1705.
7. B.J. Van Lenten, A.C. Wagner, C.L. Jung, P. Ruchala, A.J. Waring, R.I. Lehrer, A.D. Watson, S. Hama, M. Navab, G.M. Anantharamaiah, A.M. Fogelman, Antiinflammatory apoA-I-mimetic peptides bind oxidized lipidswith much higher affinity than human apoA-I, J. Lipid Res. 49 (2008) 2302-2311.
8. J.S. Marino, S.J. Peterson, M. Li, L. Vanella, K. Sodhi, J.W. Hill, N.G. Abraham, ApoA-1 mimetic restores adiponectin expression and insulin sensitivity independent of changes in body weight in female obese mice, Nutr. Diabetes 2 (2012) e33.
9. S.J. Peterson, G. Drummond, D.H. Kim, M. Li, A.L. Kruger, S. Ikehara, N.G. Abraham, L- 4F treatment reduces adiposity, increases adiponectin levels, and improves insulin sensitivity in obese mice, J. Lipid Res. 49 (2008) 1658-1669.
10. N.D. Vaziri, Y. Bai, J. Yuan, H.L. Said, W. Sigala, Z. Ni, ApoA-1 mimetic peptide reverses uremia-induced upregulation of pro-atherogenic pathways in the aorta, Am. J. Nephrol. 32 (2010) 201-211.
11. C.E. Watson, N. Weissbach, L. Kjems, S. Ayalasomayajula, Y. Zhang, I. Chang, M. Navab, S. Hama, G. Hough, S.T. Reddy, D. Soffer, D.J. Rader, A.M. Fogelman, A. Schecter, Treatment of patients with cardiovascular disease with L-4F, an apo-A1 mimetic, did not improve select biomarkers of HDL function, J. Lipid Res. 52 (2011) 361-373.
12. B.J. Van Lenten, A.C. Wagner, M. Navab, G.M. Anantharamaiah, S. Hama, S.T. Reddy, A.M. Fogelman, Lipoprotein inflammatory properties and serum amyloid A levels but not cholesterol levels predict lesion area in cholesterol-fed rabbits, J. Lipid Res. 48 (2007) 2344-2353.
13. M.K. Pastuszka, S.M. Janib, I. Weitzhandler, C.T. Okamoto, S. Hamm-Alvarez, J.A. Mackay, A tunable and reversible platform for the intracellular formation of genetically engineered proteinmicrodomains, Biomacromolecules 13 (2012) 3439-3444.
14. J.A.Mackay, A. Chilkoti, Temperature sensitive peptides: engineering hyperthermiadirected therapeutics, Int. J. Hyperthermia 24 (2008) 483-495.
15. P. Shi, J.A. Gustafson, J.A. MacKay, Genetically engineered nanocarriers for drug delivery, Int. J. Nanomedicine 9 (2014) 1617-1626.
16. W. Hassouneh, S.R. MacEwan, A. Chilkoti, Fusions of elastin-like polypeptides to pharmaceutical proteins, Methods Enzymol. 502 (2012) 215-237.
17. S.M. Janib, J.A. Gustafson, R.O.Minea, S.D. Swenson, S. Liu, M.K. Pastuszka, L.L. Lock, H. Cui, F.S.Markland, P.S. Conti, Z. Li, J.A.MacKay, Multimeric disintegrin protein polymer fusions that target tumor vasculature, Biomacromolecules 5 (2014) 2347-2358.
18. S.M. Janib, M. Pastuszka, S. Aluri, Z. Folchman-Wagner, P.Y. Hsueh, P. Shi, A. Yi, H. Cui, J.A. Mackay, A quantitative recipe for engineering protein polymer nanoparticles, Polym. Chem. 5 (2014) 1614-1625.
19. S.M. Janib, S. Liu, R. Park, M.K. Pastuszka, P. Shi, A.S. Moses, M.M. Orosco, Y.A. Lin, H. Cui, P.S. Conti, Z. Li, J.A. MacKay, Kinetic quantification of protein polymer nanoparticles using non-invasive imaging, Integr. Biol. (Camb.) 5 (2013) 183-194.
20. D.W. Urry, Physical chemistry of biological free energy transduction as demonstrated by elastic protein-based polymers, J. Phys. Chem. B. 101 (1997) 11007-11028.
21. J.A. Mackay, D.J. Callahan, K.N. Fitzgerald, A. Chilkoti, Quantitative model of the phase behavior of recombinant pH-responsive elastin-like polypeptides, Biomacromolecules 11 (2010) 2873-2879.
22. J.R.McDaniel, D.C. Radford, A. Chilkoti, A unified model for de novo design of elastinlike polypeptides with tunable inverse transition temperatures, Biomacromolecules 14 (2013) 2866-2872.
23. D. Osei-Hwedieh, Apolipoprotein mimetic peptides: mechanisms of action as antiatherogenic agents, Pharmacol. Ther. 130 (2012) 83-91.
24. K. Yamaoka, T. Nouchi, F. Marumo, C. Sato, Alpha-smooth-muscle actin expression in normal and fibrotic human livers, Dig. Dis. Sci. 38 (1993) 1473-1479.
25. A. Chilkoti, T. Christensen, J.A. MacKay, Stimulus responsive elastin biopolymers: Applications inmedicine and biotechnology, Curr. Opin. Chem. Biol. 10 (2006) 652-657.
26. M. Shah, M.C. Edman, S.R. Janga, P. Shi, J. Dhandhukia, S. Liu, S.G. Louie, K. Rodgers, J. A. Mackay, S.F. Hamm-Alvarez, A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjogren's syndrome, J. Control. Release 171 (2013) 269-279.
27. P. Shi, S. Aluri, Y.A. Lin, M. Shah, M. Edman, J. Dhandhukia, H. Cui, J.A. MacKay, Elastin-based protein polymer nanoparticles carrying drug at both corona and core suppress tumor growth in vivo, J. Control. Release 171 (2013) 330-338.
28. D.E. Discher, F. Ahmed, Polymersomes, Annu. Rev. Biomed. Eng. 8 (2006) 323-341.
29. E.G. Bellomo, M.D. Wyrsta, L. Pakstis, D.J. Pochan, T.J. Deming, Stimuli-responsive polypeptide vesicles by conformation-specific assembly, Nat. Mater. 3 (2004) 244-248.
30. J.R. McDaniel, S.R. MacEwan, X. Li, D.C. Radford, C.D. Landon, M. Dewhirst, A. Chilkoti, Rational design of "heat seeking" drug loaded polypeptide nanoparticles that thermally target solid tumors, Nano Lett. 14 (2014) 2890-2895.
31. S.M. Park, M.S. Kim, S.J. Park, E.S. Park, K.S. Choi, Y.S. Kim, H.R. Kim, Novel temperature-triggered liposomewith high stability: formulation, in vitro evaluation, and in vivo study combined with high-intensity focused ultrasound (HIFU), J. Control. Release 170 (2013) 373-379.
32. G. Kong, G. Anyarambhatla, W.P. Petros, R.D. Braun, O.M. Colvin, D. Needham, M.W. Dewhirst, Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release, Cancer Res. 60 (2000) 6950-6957.
33. A.R. Rodriguez, J.R. Kramer, T.J. Deming, Enzyme-triggered cargo release from methionine sulfoxide containing copolypeptide vesicles, Biomacromolecules 14 (2013) 3610-3614.
34. P. Tanner, P. Baumann, R. Enea, O. Onaca, C. Palivan, W. Meier, Polymeric vesicles: from drug carriers to nanoreactors and artificial organelles, Acc. Chem. Res. 44 (2011) 1039-1049.
35. K.B. Vargo, R. Parthasarathy, D.A. Hammer, Self-assembly of tunable protein suprastructures from recombinant oleosin, Proc. Natl. Acad. Sci. U. S. A. 109 (2012) 11657-11662.
36. B.A. Lewis, D.M. Engelman, Lipid bilayer thickness varies linearly with acyl chain length in fluid phosphatidylcholine vesicles, J. Mol. Biol. 166 (1983) 211-217.
37. M.C. Woodle, D.D. Lasic, Sterically stabilized liposomes, Biochim. Biophys. Acta 1113 (1992) 171-199.
38. V. Schellenberger, C.W. Wang, N.C. Geething, B.J. Spink, A. Campbell, W. To, M.D. Scholle, Y. Yin, Y. Yao, O. Bogin, J.L. Cleland, J. Silverman, W.P.C. Stemmer, A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner, Nat. Biotechnol. 27 (2009) 1186-U1155.
39. L. Martin, E. Castro, A. Ribeiro, M. Alonso, J.C. Rodriguez-Cabello, Temperaturetriggered self-assembly of elastin-like block co-recombinamers: The controlled formation of micelles and vesicles in an aqueous medium, Biomacromolecules 13 (2012) 293-298.