Rational design of "heat seeking" drug loaded polypeptide nanoparticles that thermally target solid tumors

Nano Letters

Volumn 14, Issue 5, 2014, Pages 2890-2895

  McDaniel, Jonathan R ^a,c   Macewan, Sarah R ^a   Li, Xinghai ^a   Radford, D Christopher ^a,d   Landon, Chelsea D ^b   Dewhirst, Mark ^b   Chilkoti, Ashutosh ^a  

^a Duke University   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c The University of Texas at Austin   (United States)

^d Department of Electrical and Computer Engineering   (United States)

Author keywords

drug delivery; Elastin like polypeptides; hyperthermia; nanoparticles; thermal targeting; thermosensitive

Indexed keywords

DRUG DELIVERY; FLUORESCENCE MICROSCOPY; POLYPEPTIDES; TUMORS;

CANCER CHEMOTHERAPEUTICS; CONFOCAL FLUORESCENCE MICROSCOPY; ELASTIN-LIKE POLYPEPTIDES; HYPERTHERMIA; NARROW TEMPERATURE RANGES; THERMAL TARGETING; THERMALLY RESPONSIVE; THERMO SENSITIVE;

NANOPARTICLES;

ANTINEOPLASTIC AGENT; ELASTIN; NANOPARTICLE; PEPTIDE;

ANIMAL; CHEMISTRY; COLONIC NEOPLASMS; DRUG DELIVERY SYSTEM; HUMAN; MOUSE; TEMPERATURE; THERMOTHERAPY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; COLONIC NEOPLASMS; DRUG DELIVERY SYSTEMS; ELASTIN; HUMANS; HYPERTHERMIA, INDUCED; MICE; NANOPARTICLES; PEPTIDES; TEMPERATURE;

EID: 84900466456     PISSN: 15306984     EISSN: 15306992     Source Type: Journal    
DOI: 10.1021/nl5009376     Document Type: Article

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