A monoterpene, unique component of thyme honeys, induces apoptosis in prostate cancer cells via inhibition of NF-κB activity and IL-6 secretion

Phytomedicine

Volumn 21, Issue 11, 2014, Pages 1483-1489

  Kassi, Eva ^a   Chinou, Ioanna ^b   Spilioti, Eliana ^a   Tsiapara, Anna ^a   Graikou, Konstantia ^b   Karabournioti, Sofia ^a   Manoussakis, Menelaos ^a   Moutsatsou, Paraskevi ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

Author keywords

Apoptosis; Interleukin 6; Monoterpene; NF B; Prostate cancer cells; Trihydoxy ketone

Indexed keywords

4 (1,2,4 TRIHYDROXY 2,6,6 TRIMETHYLCYCLOHEXYL) BUT 3 EN 2 ONE; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; DEXAMETHASONE; FLUCYTOSINE; FLUORESCEIN ISOTHIOCYANATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; ITRACONAZOLE; KETONE DERIVATIVE; LIPOCORTIN 5; NETILMICIN; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TERPENE; THREONINE; TYROSINE; UNCLASSIFIED DRUG; IL6 PROTEIN, HUMAN; KETONE; RELA PROTEIN, HUMAN; TRANSCRIPTION FACTOR RELA;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG EFFECT; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; FUNGUS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; GREECE; HONEY; HUMAN; HUMAN CELL; MINIMUM INHIBITORY CONCENTRATION; MTT ASSAY; NONHUMAN; PHYTOCHEMISTRY; PRIORITY JOURNAL; PROSTATE CANCER CELL LINE; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THYME; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; MALE; METABOLISM; MICROBIAL SENSITIVITY TEST; PHOSPHORYLATION; PROSTATE TUMOR; SECRETION (PROCESS); THYMUS (PLANT); TUMOR CELL LINE;

FUNGI; THYMUS VULGARIS;

ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; GREECE; HONEY; HUMANS; INTERLEUKIN-6; KETONES; MALE; MAP KINASE SIGNALING SYSTEM; MICROBIAL SENSITIVITY TESTS; MONOTERPENES; PHOSPHORYLATION; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; THYMUS PLANT; TRANSCRIPTION FACTOR RELA;

EID: 84906938883     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2014.04.032     Document Type: Article

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