Apoptosis initiation of β-ionone in SGC-7901 gastric carcinoma cancer cells via a PI3K-AKT pathway

Archives of Toxicology

Volumn 87, Issue 3, 2013, Pages 481-490

  Liu, Qian ^a   Dong, Hong Wei ^b   Sun, Wen Guang ^b   Liu, Ming ^b   Ibla, Juan C ^c   Liu, Lian Xin ^b   Parry, John W ^d   Han, Xiao Hui ^c   Li, Ming Song ^e,f   Liu, Jia Ren ^b,c  

^a GANNAN MEDICAL UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

^c HARVARD MEDICAL SCHOOL   (United States)

^d VIRGINIA STATE UNIVERSITY   (United States)

^e SOUTHERN MEDICAL UNIVERSITY   (China)

^f Guangdong Provincial Key Laboratory of Gastroenterology   (China)

Author keywords

ionone; Apoptosis initiation; PI3K AKT pathway; SGC 7901 cells

Indexed keywords

BETA IONONE; CASPASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE B;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; STOMACH CARCINOMA;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; CELL NUCLEUS SHAPE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; NORISOPRENOIDS; PHOSPHATIDYLINOSITOL 3-KINASE; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TIME FACTORS;

EID: 84877250149     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0962-8     Document Type: Article

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