-
1
-
-
0027164941
-
Randomized comparison of busulfan and hydroxyurea in chronic myelogenous leukemia: prolongation of survival by hydroxyurea. The German CML Study Group
-
Hehlmann R., Heimpel H., Hasford J., Kolb H.J., Pralle H., Hossfeld D.K., et al. Randomized comparison of busulfan and hydroxyurea in chronic myelogenous leukemia: prolongation of survival by hydroxyurea. The German CML Study Group. Blood 1993, 82:398-407.
-
(1993)
Blood
, vol.82
, pp. 398-407
-
-
Hehlmann, R.1
Heimpel, H.2
Hasford, J.3
Kolb, H.J.4
Pralle, H.5
Hossfeld, D.K.6
-
2
-
-
0028813711
-
Prolonged survival in chronic myelogenous leukemia after cytogenetic response to interferon-alpha therapy
-
Kantarjian H.M., Smith T.L., O'Brien S., Beran M., Pierce S., Talpaz M. Prolonged survival in chronic myelogenous leukemia after cytogenetic response to interferon-alpha therapy. Ann Intern Med 1995, 122:254-261.
-
(1995)
Ann Intern Med
, vol.122
, pp. 254-261
-
-
Kantarjian, H.M.1
Smith, T.L.2
O'Brien, S.3
Beran, M.4
Pierce, S.5
Talpaz, M.6
-
3
-
-
0345696854
-
Interferon alfa-2b combined with cytarabine versus interferon alone in chronic myelogenous leukemia
-
Guilhot F., Chastang C., Michallet M., Guerci A., Harousseau J.L., Maloisel F., et al. Interferon alfa-2b combined with cytarabine versus interferon alone in chronic myelogenous leukemia. N Engl J Med 1997, 337:223-229.
-
(1997)
N Engl J Med
, vol.337
, pp. 223-229
-
-
Guilhot, F.1
Chastang, C.2
Michallet, M.3
Guerci, A.4
Harousseau, J.L.5
Maloisel, F.6
-
4
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of BCR-ABL positive cells
-
Druker B.J., Tamura S., Buchdunger E., Ohno S., Segal G.M., Fanning S., et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of BCR-ABL positive cells. Nat Med 1996, 2:561-566.
-
(1996)
Nat Med
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
Ohno, S.4
Segal, G.M.5
Fanning, S.6
-
5
-
-
0037186915
-
Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
-
Kantarjian H., Sawyers C., Hochhaus A., Guilhot F., Schiffer C., Gambacorti-Passerini C., et al. Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. N Engl J Med 2002, 346:645-652.
-
(2002)
N Engl J Med
, vol.346
, pp. 645-652
-
-
Kantarjian, H.1
Sawyers, C.2
Hochhaus, A.3
Guilhot, F.4
Schiffer, C.5
Gambacorti-Passerini, C.6
-
6
-
-
10744233716
-
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
-
O'Brien S.G., Guilhot F., Larson R.A., Gathmann I., Baccarani M., Cervantes F., et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med 2003, 348:994-1004.
-
(2003)
N Engl J Med
, vol.348
, pp. 994-1004
-
-
O'Brien, S.G.1
Guilhot, F.2
Larson, R.A.3
Gathmann, I.4
Baccarani, M.5
Cervantes, F.6
-
7
-
-
67349233062
-
Six-year follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia
-
Hochhaus A., O'Brien S.G., Guilhot F., Druker B.J., Branford S., Foroni L., et al. Six-year follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia. Leukemia 2009, 23:1054-1061.
-
(2009)
Leukemia
, vol.23
, pp. 1054-1061
-
-
Hochhaus, A.1
O'Brien, S.G.2
Guilhot, F.3
Druker, B.J.4
Branford, S.5
Foroni, L.6
-
8
-
-
77949767505
-
International randomized study of interferon vs STI571 (IRIS) 8-year follow up: sustained survival and low risk for progression or events in patients with newly diagnosed chronic myeloid leukemia in chronic phase treated with imatinib
-
Deininger M., O'Brien S.G., Guilhot F., Goldman J., Hochhaus A., Hughes T.P., et al. International randomized study of interferon vs STI571 (IRIS) 8-year follow up: sustained survival and low risk for progression or events in patients with newly diagnosed chronic myeloid leukemia in chronic phase treated with imatinib. ASH Annual Meeting Abstracts 2009, 114:1126.
-
(2009)
ASH Annual Meeting Abstracts
, vol.114
, pp. 1126
-
-
Deininger, M.1
O'Brien, S.G.2
Guilhot, F.3
Goldman, J.4
Hochhaus, A.5
Hughes, T.P.6
-
9
-
-
49149111543
-
Imatinib for newly diagnosed patients with chronic myeloid leukemia: incidence of sustained responses in an intention-to-treat analysis
-
de Lavallade H., Apperley J.F., Khorashad J.S., Milojkovic D., Reid A.G., Bua M., et al. Imatinib for newly diagnosed patients with chronic myeloid leukemia: incidence of sustained responses in an intention-to-treat analysis. J Clin Oncol 2008, 26:3358-3363.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3358-3363
-
-
de Lavallade, H.1
Apperley, J.F.2
Khorashad, J.S.3
Milojkovic, D.4
Reid, A.G.5
Bua, M.6
-
10
-
-
33846228789
-
Contribution of ABL kinase domain mutations to imatinib resistance in different subsets of Philadelphia-positive patients: by the GIMEMA Working Party on Chronic Myeloid Leukemia
-
Soverini S., Colarossi S., Gnani A., Rosti G., Castagnetti F., et al. Contribution of ABL kinase domain mutations to imatinib resistance in different subsets of Philadelphia-positive patients: by the GIMEMA Working Party on Chronic Myeloid Leukemia. Clin Cancer Res 2006, 12:7374-7379.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 7374-7379
-
-
Soverini, S.1
Colarossi, S.2
Gnani, A.3
Rosti, G.4
Castagnetti, F.5
-
11
-
-
33750077276
-
Frequency and clinical significance of BCR-ABL mutations in patients with chronic myeloid leukemia treated with imatinib mesylate
-
Jabbour E., Kantarjian H., Jones D., Talpaz M., Bekele N., O'Brien S., et al. Frequency and clinical significance of BCR-ABL mutations in patients with chronic myeloid leukemia treated with imatinib mesylate. Leukemia 2006, 20:1767-1773.
-
(2006)
Leukemia
, vol.20
, pp. 1767-1773
-
-
Jabbour, E.1
Kantarjian, H.2
Jones, D.3
Talpaz, M.4
Bekele, N.5
O'Brien, S.6
-
12
-
-
37049003546
-
Dynamics of BCR-ABL kinase domain mutations in chronic myeloid leukemia after sequential treatment with multiple tyrosine kinase inhibitors
-
Cortes J., Jabbour E., Kantarjian H., Yin C.C., Shan J., O'Brien S., et al. Dynamics of BCR-ABL kinase domain mutations in chronic myeloid leukemia after sequential treatment with multiple tyrosine kinase inhibitors. Blood 2007, 110:4005-4011.
-
(2007)
Blood
, vol.110
, pp. 4005-4011
-
-
Cortes, J.1
Jabbour, E.2
Kantarjian, H.3
Yin, C.C.4
Shan, J.5
O'Brien, S.6
-
13
-
-
84906938385
-
-
[Princeton, NJ. Bristol-Myers Squibb Company], 6, 2013
-
Sprycel (dasatinib) package insert 6/2013, [Princeton, NJ. Bristol-Myers Squibb Company].
-
Sprycel (dasatinib) package insert
-
-
-
14
-
-
79951488325
-
-
[East Hanover, NJ. Novartis Pharmaceuticals Corporation], 1, 2014
-
Tasigna (nilotinib) package insert 1/2014, [East Hanover, NJ. Novartis Pharmaceuticals Corporation].
-
Tasigna (nilotinib) package insert
-
-
-
15
-
-
77953725855
-
Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia
-
Kantarjian H., Shah N.P., Hochhaus A., Cortes J., Shah S., Avala M., et al. Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med 2010, 362:2260-2270.
-
(2010)
N Engl J Med
, vol.362
, pp. 2260-2270
-
-
Kantarjian, H.1
Shah, N.P.2
Hochhaus, A.3
Cortes, J.4
Shah, S.5
Avala, M.6
-
16
-
-
77953691179
-
Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia
-
Saglio G., Kim D.W., Issaragrisil S., le Coutre P., Etienne G., Lobo C., et al. Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia. N Engl J Med 2010, 362:2251-2259.
-
(2010)
N Engl J Med
, vol.362
, pp. 2251-2259
-
-
Saglio, G.1
Kim, D.W.2
Issaragrisil, S.3
le Coutre, P.4
Etienne, G.5
Lobo, C.6
-
18
-
-
70350507997
-
AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance
-
O'Hare T., Shakespeare W.C., Zhu X., Eide C.A., Rivera V.M., Wang F., et al. AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance. Cancer Cell 2009, 16:401-412.
-
(2009)
Cancer Cell
, vol.16
, pp. 401-412
-
-
O'Hare, T.1
Shakespeare, W.C.2
Zhu, X.3
Eide, C.A.4
Rivera, V.M.5
Wang, F.6
-
19
-
-
84893136765
-
Early response with dasatinib or imatinib in chronic myeloid leukemia: 3-year follow-up from a randomized phase 3 trial (DASISION)
-
Jabbour E., Kantarjian H.M., Saglio G., Steegmann J.L., Shah N.P., Boque C., et al. Early response with dasatinib or imatinib in chronic myeloid leukemia: 3-year follow-up from a randomized phase 3 trial (DASISION). Blood 2014, 123:494-500.
-
(2014)
Blood
, vol.123
, pp. 494-500
-
-
Jabbour, E.1
Kantarjian, H.M.2
Saglio, G.3
Steegmann, J.L.4
Shah, N.P.5
Boque, C.6
-
20
-
-
84868552615
-
A randomized trial of dasatinib 100mg versus imatinib 400mg in newly diagnosed chronic-phase chronic myeloid leukemia
-
Radich J.P., Kopecky K.J., Appelbaum F.R., Kamel-Reid S., Malnassy G., Paietta E., et al. A randomized trial of dasatinib 100mg versus imatinib 400mg in newly diagnosed chronic-phase chronic myeloid leukemia. Blood 2012, 120:3898-3905.
-
(2012)
Blood
, vol.120
, pp. 3898-3905
-
-
Radich, J.P.1
Kopecky, K.J.2
Appelbaum, F.R.3
Kamel-Reid, S.4
Malnassy, G.5
Paietta, E.6
-
21
-
-
84867395848
-
Nilotinib vs imatinib in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow up
-
Larson R.A., Hochhaus A., Clark R.E., Etienne G., Kim D.-W., Flinn I.W., et al. Nilotinib vs imatinib in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow up. Leukemia 2012, 26:2197-2203.
-
(2012)
Leukemia
, vol.26
, pp. 2197-2203
-
-
Larson, R.A.1
Hochhaus, A.2
Clark, R.E.3
Etienne, G.4
Kim, D.-W.5
Flinn, I.W.6
-
22
-
-
84866175467
-
Bosutinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: results from the BELA trial
-
Cortes J.E., Kim D.W., Kantarjian H.M., Brummendorf T.H., Dyagil I., Griskevicius L., et al. Bosutinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: results from the BELA trial. J Clin Oncol 2012, 30:3486-3492.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3486-3492
-
-
Cortes, J.E.1
Kim, D.W.2
Kantarjian, H.M.3
Brummendorf, T.H.4
Dyagil, I.5
Griskevicius, L.6
-
23
-
-
75749105885
-
Phase III, randomized, open-label study of daily imatinib mesylate 400mg versus 800mg in patients with newly diagnosed, previously untreated chronic myeloid leukemia in chronic phase using molecular end points: tyrosine kinase inhibitor optimization and selectivity study
-
Cortes J.E., Baccarani M., Guilhot F., Druker B.J., Kim D.W., Pane F., et al. Phase III, randomized, open-label study of daily imatinib mesylate 400mg versus 800mg in patients with newly diagnosed, previously untreated chronic myeloid leukemia in chronic phase using molecular end points: tyrosine kinase inhibitor optimization and selectivity study. J Clin Oncol 2010, 28:424-430.
-
(2010)
J Clin Oncol
, vol.28
, pp. 424-430
-
-
Cortes, J.E.1
Baccarani, M.2
Guilhot, F.3
Druker, B.J.4
Kim, D.W.5
Pane, F.6
-
24
-
-
78650625238
-
Imatinib plus peginterferon alfa-2a in chronic myeloid leukemia
-
Preudhomme C., Guilhot J., Nicolini F.E., Guerci-Bresler A., Rigal-Huguet F., Maloisel F., et al. Imatinib plus peginterferon alfa-2a in chronic myeloid leukemia. N Engl J Med 2010, 363:2511-2521.
-
(2010)
N Engl J Med
, vol.363
, pp. 2511-2521
-
-
Preudhomme, C.1
Guilhot, J.2
Nicolini, F.E.3
Guerci-Bresler, A.4
Rigal-Huguet, F.5
Maloisel, F.6
-
25
-
-
79251527895
-
Immune modulation of minimal residual disease in early chronic phase chronic myelogenous leukemia: a randomized trial of frontline high-dose imatinib mesylate with or without pegylated interferon alpha-2b and granulocyte-macrophage colony-stimulating factor
-
Cortes J., Quintas-Cardama A., Jones D., Ravandi F., Garcia-Manero G., Verstovsek S., et al. Immune modulation of minimal residual disease in early chronic phase chronic myelogenous leukemia: a randomized trial of frontline high-dose imatinib mesylate with or without pegylated interferon alpha-2b and granulocyte-macrophage colony-stimulating factor. Cancer 2011, 117:572-580.
-
(2011)
Cancer
, vol.117
, pp. 572-580
-
-
Cortes, J.1
Quintas-Cardama, A.2
Jones, D.3
Ravandi, F.4
Garcia-Manero, G.5
Verstovsek, S.6
-
26
-
-
79955018499
-
Tolerability-adapted imatinib 800mg/d versus 400mg/d versus 400mg/d plus interferon-alpha in newly diagnosed chronic myeloid leukemia
-
Hehlmann R., Lauseker M., Jung-Munkwitz S., Leitner A., Muller M.C., Pletsch U., et al. Tolerability-adapted imatinib 800mg/d versus 400mg/d versus 400mg/d plus interferon-alpha in newly diagnosed chronic myeloid leukemia. J Clin Oncol 2011, 29:1634-1642.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1634-1642
-
-
Hehlmann, R.1
Lauseker, M.2
Jung-Munkwitz, S.3
Leitner, A.4
Muller, M.C.5
Pletsch, U.6
-
27
-
-
84860346274
-
Pulmonary arterial hypertension in patients treated by dasatinib
-
Montani D., Bergot E., Gunther S., Savale L., Bergeron A., Bourdin A., et al. Pulmonary arterial hypertension in patients treated by dasatinib. Circulation 2012, 125:2128-2137.
-
(2012)
Circulation
, vol.125
, pp. 2128-2137
-
-
Montani, D.1
Bergot, E.2
Gunther, S.3
Savale, L.4
Bergeron, A.5
Bourdin, A.6
-
28
-
-
67651089848
-
Tyrosine kinase inhibitor-induced platelet dysfunction in patients with chronic myeloid leukemia
-
Quintas-Cardama A., Han X., Kantarjian H., Cortes J. Tyrosine kinase inhibitor-induced platelet dysfunction in patients with chronic myeloid leukemia. Blood 2009, 114:261-263.
-
(2009)
Blood
, vol.114
, pp. 261-263
-
-
Quintas-Cardama, A.1
Han, X.2
Kantarjian, H.3
Cortes, J.4
-
29
-
-
66649092089
-
Bleeding diathesis in patients with chronic myeloid leukemia receiving dasatinib therapy
-
Quintas-Cardama A., Kantarjian H., Ravandi F., O'Brien S., Thomas D., Vidal-Senmache G., et al. Bleeding diathesis in patients with chronic myeloid leukemia receiving dasatinib therapy. Cancer 2009, 115:2482-2490.
-
(2009)
Cancer
, vol.115
, pp. 2482-2490
-
-
Quintas-Cardama, A.1
Kantarjian, H.2
Ravandi, F.3
O'Brien, S.4
Thomas, D.5
Vidal-Senmache, G.6
-
30
-
-
69249142682
-
Dynamics and management of cytopenias associated with dasatinib therapy in patients with chronic myeloid leukemia in chronic phase after imatinib failure
-
Quintas-Cardama A., De Souza Santos F.P., Kantarjian H., O'Brien S., Faderl S., Awais A., et al. Dynamics and management of cytopenias associated with dasatinib therapy in patients with chronic myeloid leukemia in chronic phase after imatinib failure. Cancer 2009, 115:3935-3943.
-
(2009)
Cancer
, vol.115
, pp. 3935-3943
-
-
Quintas-Cardama, A.1
De Souza Santos, F.P.2
Kantarjian, H.3
O'Brien, S.4
Faderl, S.5
Awais, A.6
-
31
-
-
84862125953
-
Clinical cardiac safety profile of nilotinib
-
Kim T.D., le Coutre P., Schwarz M., Grille P., Levitin M., Fateh-Moghadam S., et al. Clinical cardiac safety profile of nilotinib. Haematologica 2012, 97:883-889.
-
(2012)
Haematologica
, vol.97
, pp. 883-889
-
-
Kim, T.D.1
le Coutre, P.2
Schwarz, M.3
Grille, P.4
Levitin, M.5
Fateh-Moghadam, S.6
-
33
-
-
79957492218
-
Bending the cost curve in cancer care
-
Smith T.J., Hillner B.E. Bending the cost curve in cancer care. N Engl J Med 2011, 364:2060-2065.
-
(2011)
N Engl J Med
, vol.364
, pp. 2060-2065
-
-
Smith, T.J.1
Hillner, B.E.2
-
34
-
-
84886719809
-
Cancer drugs in the United States: justum pretium-the just price
-
Kantarjian H.M., Fojo T., Mathisen M., Zwelling L.A. Cancer drugs in the United States: justum pretium-the just price. J Clin Oncol 2013, 31:3600-3604.
-
(2013)
J Clin Oncol
, vol.31
, pp. 3600-3604
-
-
Kantarjian, H.M.1
Fojo, T.2
Mathisen, M.3
Zwelling, L.A.4
-
35
-
-
84880790088
-
The price of drugs for chronic myeloid leukemia is a reflection of the unsustainable prices of cancer drugs: from the perspective of a large group of CML experts
-
Experts in Chronic Myeloid Leukemia
-
Experts in Chronic Myeloid Leukemia The price of drugs for chronic myeloid leukemia is a reflection of the unsustainable prices of cancer drugs: from the perspective of a large group of CML experts. Blood 2013, 121:4439-4442.
-
(2013)
Blood
, vol.121
, pp. 4439-4442
-
-
-
36
-
-
79953880772
-
Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib
-
Gambacorti-Passerini C., Antolini L., Mahon X., Guilhot F., Deininger M., Fava C., et al. Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib. J Natl Cancer Inst 2011, 103:553-561.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 553-561
-
-
Gambacorti-Passerini, C.1
Antolini, L.2
Mahon, X.3
Guilhot, F.4
Deininger, M.5
Fava, C.6
-
37
-
-
84906936493
-
-
[East Hanover, NJ. Novartis Pharmaceuticals Corporation], 10, 2013
-
Gleevec (imatinib) package insert 10/2013, [East Hanover, NJ. Novartis Pharmaceuticals Corporation].
-
Gleevec (imatinib) package insert
-
-
-
38
-
-
84881298446
-
European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013
-
Baccarani M., Deininger M.W., Rosti G., Hochhaus A., Soverini S., Apperley J.F., et al. European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013. Blood 2013, 122:872-884.
-
(2013)
Blood
, vol.122
, pp. 872-884
-
-
Baccarani, M.1
Deininger, M.W.2
Rosti, G.3
Hochhaus, A.4
Soverini, S.5
Apperley, J.F.6
-
39
-
-
84891954191
-
Chronic myelogenous leukemia, version 1.2014
-
O'Brien S., Radich J.P., Abboud C.N., Akhtari M., Altman J.K., Berman E., et al. Chronic myelogenous leukemia, version 1.2014. J Natl Compr Canc Netw 2013, 11:1327-1340.
-
(2013)
J Natl Compr Canc Netw
, vol.11
, pp. 1327-1340
-
-
O'Brien, S.1
Radich, J.P.2
Abboud, C.N.3
Akhtari, M.4
Altman, J.K.5
Berman, E.6
-
40
-
-
73949153481
-
Chronic myeloid leukemia: a prospective comparison of interphase fluorescence in situ hybridization and chromosome banding analysis for the definition of complete cytogenetic response: a study of the GIMEMA CML WP
-
Testoni N., Marzocchi G., Luatti S., Amabile M., Baldazzi C., Stacchini M., et al. Chronic myeloid leukemia: a prospective comparison of interphase fluorescence in situ hybridization and chromosome banding analysis for the definition of complete cytogenetic response: a study of the GIMEMA CML WP. Blood 2009, 114:4939-4943.
-
(2009)
Blood
, vol.114
, pp. 4939-4943
-
-
Testoni, N.1
Marzocchi, G.2
Luatti, S.3
Amabile, M.4
Baldazzi, C.5
Stacchini, M.6
-
41
-
-
79954986886
-
Considerations in the management of patients with Philadelphia chromosome-positive chronic myeloid leukemia receiving tyrosine kinase inhibitors
-
Kantarjian H., Cortes J. Considerations in the management of patients with Philadelphia chromosome-positive chronic myeloid leukemia receiving tyrosine kinase inhibitors. J Clin Oncol 2011, 29:1512-1516.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1512-1516
-
-
Kantarjian, H.1
Cortes, J.2
-
42
-
-
68949108481
-
Significance of increasing levels of minimal residual disease in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in complete cytogenetic response
-
Kantarjian H.M., Shan J., Jones D., O'Brien S., Rios M.B., Jabbour E., et al. Significance of increasing levels of minimal residual disease in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in complete cytogenetic response. J Clin Oncol 2009, 27:3659-3663.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3659-3663
-
-
Kantarjian, H.M.1
Shan, J.2
Jones, D.3
O'Brien, S.4
Rios, M.B.5
Jabbour, E.6
-
43
-
-
84862907694
-
Assessment of BCR-ABL1 transcript levels at 3months is the only requirement for predicting outcome for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors
-
Marin D., Ibrahim A.R., Lucas C., Gerrard G., Wang L., Szydlo R.M., et al. Assessment of BCR-ABL1 transcript levels at 3months is the only requirement for predicting outcome for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors. J Clin Oncol 2012, 30:232-238.
-
(2012)
J Clin Oncol
, vol.30
, pp. 232-238
-
-
Marin, D.1
Ibrahim, A.R.2
Lucas, C.3
Gerrard, G.4
Wang, L.5
Szydlo, R.M.6
-
44
-
-
84881289808
-
Early responses predict better outcomes in patients with newly diagnosed chronic myeloid leukemia: results with four tyrosine kinase inhibitor modalities
-
Jain P., Kantarjian H., Nazha A., O'Brien S., Jabbour E., Romo C.G., et al. Early responses predict better outcomes in patients with newly diagnosed chronic myeloid leukemia: results with four tyrosine kinase inhibitor modalities. Blood 2013, 121:4867-4874.
-
(2013)
Blood
, vol.121
, pp. 4867-4874
-
-
Jain, P.1
Kantarjian, H.2
Nazha, A.3
O'Brien, S.4
Jabbour, E.5
Romo, C.G.6
-
45
-
-
84878263769
-
Combining BCR-ABL1 transcript level at 3 and 6months in chronic myeloid leukemia: implications for early intervention strategies
-
Neelakantan P., Gerrard G., Lucas C., Milojkovic D., May P., Wang L., et al. Combining BCR-ABL1 transcript level at 3 and 6months in chronic myeloid leukemia: implications for early intervention strategies. Blood 2013, 121:3739-3742.
-
(2013)
Blood
, vol.121
, pp. 3739-3742
-
-
Neelakantan, P.1
Gerrard, G.2
Lucas, C.3
Milojkovic, D.4
May, P.5
Wang, L.6
-
46
-
-
84886997780
-
Assessment at 6months may be warranted for patients with chronic myeloid leukemia with no major cytogenetic response at 3months
-
Nazha A., Kantarjian H., Jain P., Romo C., Jabbour E., Quintas-Cardama A., et al. Assessment at 6months may be warranted for patients with chronic myeloid leukemia with no major cytogenetic response at 3months. Haematologica 2013, 98:1686-1688.
-
(2013)
Haematologica
, vol.98
, pp. 1686-1688
-
-
Nazha, A.1
Kantarjian, H.2
Jain, P.3
Romo, C.4
Jabbour, E.5
Quintas-Cardama, A.6
-
47
-
-
84906937451
-
Any BRC-ABL reduction below 10% at 6months of therapy significantly improves outcome for CML patients with a poor response at 3months
-
[Abstract 254]
-
Branford S., Roberts N., Yeung D.T., Altamura H., Parker W.T., Hughes T.P. Any BRC-ABL reduction below 10% at 6months of therapy significantly improves outcome for CML patients with a poor response at 3months. Blood (ASH Annual Meeting Abstracts) 2013, 122. [Abstract 254].
-
(2013)
Blood (ASH Annual Meeting Abstracts)
, vol.122
-
-
Branford, S.1
Roberts, N.2
Yeung, D.T.3
Altamura, H.4
Parker, W.T.5
Hughes, T.P.6
-
49
-
-
0037166985
-
Long-term persistence in use of statin therapy in elderly patients
-
Benner J.S., Glynn R.J., Mogun H., Neumann P.J., Weinstein M.C., Avorn J. Long-term persistence in use of statin therapy in elderly patients. JAMA 2002, 288:455-461.
-
(2002)
JAMA
, vol.288
, pp. 455-461
-
-
Benner, J.S.1
Glynn, R.J.2
Mogun, H.3
Neumann, P.J.4
Weinstein, M.C.5
Avorn, J.6
-
50
-
-
84897019740
-
Cost sharing and adherence to tyrosine kinase inhibitors for patients with chronic myeloid leukemia
-
Dusetzina S.B., Winn A.N., Abel G.A., Huskamp H.A., Keating N.L. Cost sharing and adherence to tyrosine kinase inhibitors for patients with chronic myeloid leukemia. J Clin Oncol 2014, 32:306-311.
-
(2014)
J Clin Oncol
, vol.32
, pp. 306-311
-
-
Dusetzina, S.B.1
Winn, A.N.2
Abel, G.A.3
Huskamp, H.A.4
Keating, N.L.5
-
51
-
-
77952467377
-
Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib
-
Marin D., Bazeos A., Mahon F.X., Eliasson L., Milojkovic D., Bua M., et al. Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib. J Clin Oncol 2010, 28:2381-2388.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2381-2388
-
-
Marin, D.1
Bazeos, A.2
Mahon, F.X.3
Eliasson, L.4
Milojkovic, D.5
Bua, M.6
-
52
-
-
79953823237
-
Poor adherence is the main reason for loss of CCyR and imatinib failure for chronic myeloid leukemia patients on long-term therapy
-
Ibrahim A.R., Eliasson L., Apperley J.F., Milojkovic D., Bua M., Szydlo R., et al. Poor adherence is the main reason for loss of CCyR and imatinib failure for chronic myeloid leukemia patients on long-term therapy. Blood 2011, 117:3733-3736.
-
(2011)
Blood
, vol.117
, pp. 3733-3736
-
-
Ibrahim, A.R.1
Eliasson, L.2
Apperley, J.F.3
Milojkovic, D.4
Bua, M.5
Szydlo, R.6
-
53
-
-
77649221871
-
Healthcare resource utilization and costs associated with non-adherence to imatinib treatment in chronic myeloid leukemia patients
-
Wu E.Q., Johnson S., Beaulieu N., Arana M., Bollu V., Guo A., et al. Healthcare resource utilization and costs associated with non-adherence to imatinib treatment in chronic myeloid leukemia patients. Curr Med Res Opin 2010, 26:61-69.
-
(2010)
Curr Med Res Opin
, vol.26
, pp. 61-69
-
-
Wu, E.Q.1
Johnson, S.2
Beaulieu, N.3
Arana, M.4
Bollu, V.5
Guo, A.6
-
54
-
-
84862555569
-
Patient adherence to tyrosine kinase inhibitor therapy in chronic myeloid leukemia
-
Jabbour E.J., Kantarjian H., Eliasson L., Cornelison A.M., Marin D. Patient adherence to tyrosine kinase inhibitor therapy in chronic myeloid leukemia. Am J Hematol 2012, 87:687-691.
-
(2012)
Am J Hematol
, vol.87
, pp. 687-691
-
-
Jabbour, E.J.1
Kantarjian, H.2
Eliasson, L.3
Cornelison, A.M.4
Marin, D.5
-
55
-
-
84897569767
-
Patient with chronic myeloid leukemia in complete cytogenetic response: what does it mean, and what does one do next?
-
Marin D. Patient with chronic myeloid leukemia in complete cytogenetic response: what does it mean, and what does one do next?. J Clin Oncol 2014, 32:379-384.
-
(2014)
J Clin Oncol
, vol.32
, pp. 379-384
-
-
Marin, D.1
-
56
-
-
81155133285
-
Front-line therapy with second-generation tyrosine kinase inhibitors in patients with early chronic phase chronic myeloid leukemia: what is the optimal response?
-
Jabbour E., Kantarjian H.M., O'Brien S., Shan J., Quintas-Cardama A., Garcia-Manero G., et al. Front-line therapy with second-generation tyrosine kinase inhibitors in patients with early chronic phase chronic myeloid leukemia: what is the optimal response?. J Clin Oncol 2011, 29:4260-4265.
-
(2011)
J Clin Oncol
, vol.29
, pp. 4260-4265
-
-
Jabbour, E.1
Kantarjian, H.M.2
O'Brien, S.3
Shan, J.4
Quintas-Cardama, A.5
Garcia-Manero, G.6
-
57
-
-
84898047697
-
Switching to nilotinib in patients with chronic myeloid leukemia in chronic phase with suboptimal cytogenetic response on imatinib: first results of the LASOR trial
-
Cortes J.E., De Souza C.A., Lopez J.L., Ayala M., Bullorsky E., Huang X., et al. Switching to nilotinib in patients with chronic myeloid leukemia in chronic phase with suboptimal cytogenetic response on imatinib: first results of the LASOR trial. Blood (ASH Annual Meeting Abstracts) 2013, 122:95.
-
(2013)
Blood (ASH Annual Meeting Abstracts)
, vol.122
, pp. 95
-
-
Cortes, J.E.1
De Souza, C.A.2
Lopez, J.L.3
Ayala, M.4
Bullorsky, E.5
Huang, X.6
-
58
-
-
84898028896
-
Achievement and maintenance of deeper molecular response by switching to nilotinib in patients with chronic myeloid leukemia in chronic phase with residual disease on long-term imatinib: ENESTcmr 36-month follow up
-
Leber B., Cervantes F., Spector N., Lipton J.H., Etienne G., Pasquini R., et al. Achievement and maintenance of deeper molecular response by switching to nilotinib in patients with chronic myeloid leukemia in chronic phase with residual disease on long-term imatinib: ENESTcmr 36-month follow up. Blood (ASH Annual Meeting Abstracts) 2013, 94.
-
(2013)
Blood (ASH Annual Meeting Abstracts)
, pp. 94
-
-
Leber, B.1
Cervantes, F.2
Spector, N.3
Lipton, J.H.4
Etienne, G.5
Pasquini, R.6
-
59
-
-
76549116248
-
Potent, transient inhibition of BCR-ABL with dasatinib 100mg daily achieves rapid and durable cytogenetic responses and high transformation-free survival rates in chronic phase chronic myeloid leukemia patients with resistance, suboptimal response or intolerance to imatinib
-
Shah N.P., Kim D.W., Kantarjian H., Rousselot P., Llacer P.E., Enrico A., et al. Potent, transient inhibition of BCR-ABL with dasatinib 100mg daily achieves rapid and durable cytogenetic responses and high transformation-free survival rates in chronic phase chronic myeloid leukemia patients with resistance, suboptimal response or intolerance to imatinib. Haematologica 2010, 95:232-240.
-
(2010)
Haematologica
, vol.95
, pp. 232-240
-
-
Shah, N.P.1
Kim, D.W.2
Kantarjian, H.3
Rousselot, P.4
Llacer, P.E.5
Enrico, A.6
-
60
-
-
79251546724
-
Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow up results
-
Kantarjian H.M., Giles F.J., Bhalla K.N., Pinilla-Ibarz J., Larson R.A., Gattermann N., et al. Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow up results. Blood 2011, 117:1141-1145.
-
(2011)
Blood
, vol.117
, pp. 1141-1145
-
-
Kantarjian, H.M.1
Giles, F.J.2
Bhalla, K.N.3
Pinilla-Ibarz, J.4
Larson, R.A.5
Gattermann, N.6
-
61
-
-
80055070888
-
Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome-positive chronic myeloid leukemia patients with resistance or intolerance to imatinib
-
Cortes J.E., Kantarjian H.M., Brummendorf T.H., Kim D.W., Turkina A.G., Shen Z.X., et al. Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome-positive chronic myeloid leukemia patients with resistance or intolerance to imatinib. Blood 2011, 118:4567-4576.
-
(2011)
Blood
, vol.118
, pp. 4567-4576
-
-
Cortes, J.E.1
Kantarjian, H.M.2
Brummendorf, T.H.3
Kim, D.W.4
Turkina, A.G.5
Shen, Z.X.6
-
62
-
-
64049099666
-
Imatinib mesylate dose escalation is associated with durable responses in patients with chronic myeloid leukemia after cytogenetic failure on standard-dose therapy
-
Jabbour E., Kantarjian H.M., Jones D., Shan J., O'Brien S., Reddy N., et al. Imatinib mesylate dose escalation is associated with durable responses in patients with chronic myeloid leukemia after cytogenetic failure on standard-dose therapy. Blood 2009, 113:2154-2160.
-
(2009)
Blood
, vol.113
, pp. 2154-2160
-
-
Jabbour, E.1
Kantarjian, H.M.2
Jones, D.3
Shan, J.4
O'Brien, S.5
Reddy, N.6
-
63
-
-
70149105272
-
Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia resistant to imatinib at a dose of 400 to 600milligrams daily: two-year follow-up of a randomized phase 2 study (START-R)
-
Kantarjian H., Pasquini R., Levy V., Jootar S., Holowiecki J., Hamerschlak N., et al. Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia resistant to imatinib at a dose of 400 to 600milligrams daily: two-year follow-up of a randomized phase 2 study (START-R). Cancer 2009, 115:4136-4147.
-
(2009)
Cancer
, vol.115
, pp. 4136-4147
-
-
Kantarjian, H.1
Pasquini, R.2
Levy, V.3
Jootar, S.4
Holowiecki, J.5
Hamerschlak, N.6
-
64
-
-
78650159009
-
Structural mechanism of the pan-BCR-ABL inhibitor ponatinib (AP24534): lessons for overcoming kinase inhibitor resistance
-
Zhou T., Commodore L., Huang W.S., Wang Y., Thomas M., Keats J., et al. Structural mechanism of the pan-BCR-ABL inhibitor ponatinib (AP24534): lessons for overcoming kinase inhibitor resistance. Chem Biol Drug Des 2011, 77:1-11.
-
(2011)
Chem Biol Drug Des
, vol.77
, pp. 1-11
-
-
Zhou, T.1
Commodore, L.2
Huang, W.S.3
Wang, Y.4
Thomas, M.5
Keats, J.6
-
65
-
-
84887127701
-
A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias
-
Cortes J.E., Kim D.W., Pinilla-Ibarz J., le Coutre P., Paquette R., Chuah C., et al. A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias. N Engl J Med 2013, 369:1783-1796.
-
(2013)
N Engl J Med
, vol.369
, pp. 1783-1796
-
-
Cortes, J.E.1
Kim, D.W.2
Pinilla-Ibarz, J.3
le Coutre, P.4
Paquette, R.5
Chuah, C.6
-
66
-
-
79955400117
-
Practical advice for determining the role of BCR-ABL mutations in guiding tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia
-
Jabbour E., Branford S., Saglio G., Jones D. Practical advice for determining the role of BCR-ABL mutations in guiding tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia. Cancer 2011, 117:1800-1811.
-
(2011)
Cancer
, vol.117
, pp. 1800-1811
-
-
Jabbour, E.1
Branford, S.2
Saglio, G.3
Jones, D.4
-
67
-
-
73949105873
-
Dasatinib treatment of chronic-phase chronic myeloid leukemia: analysis of responses according to preexisting BCR-ABL mutations
-
Muller M.C., Cortes J.E., Kim D.W., Druker B.J., Erben P., Pasquini R., et al. Dasatinib treatment of chronic-phase chronic myeloid leukemia: analysis of responses according to preexisting BCR-ABL mutations. Blood 2009, 114:4944-4953.
-
(2009)
Blood
, vol.114
, pp. 4944-4953
-
-
Muller, M.C.1
Cortes, J.E.2
Kim, D.W.3
Druker, B.J.4
Erben, P.5
Pasquini, R.6
-
68
-
-
70249105789
-
Impact of baseline BCR-ABL mutations on response to nilotinib in patients with chronic myeloid leukemia in chronic phase
-
Hughes T., Saglio G., Branford S., Soverini S., Kim D.W., Muller M.C., et al. Impact of baseline BCR-ABL mutations on response to nilotinib in patients with chronic myeloid leukemia in chronic phase. J Clin Oncol 2009, 27:4204-4210.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4204-4210
-
-
Hughes, T.1
Saglio, G.2
Branford, S.3
Soverini, S.4
Kim, D.W.5
Muller, M.C.6
-
69
-
-
84896622957
-
Bosutinib safety and management of toxicity in leukemia patients with resistance or intolerance to imatinib and other tyrosine kinase inhibitors
-
Kantarjian H.M., Cortes J.E., Kim D.W., Khoury H.J., Brummendorf T.H., Porkka K., et al. Bosutinib safety and management of toxicity in leukemia patients with resistance or intolerance to imatinib and other tyrosine kinase inhibitors. Blood 2014, 123:1309-1318.
-
(2014)
Blood
, vol.123
, pp. 1309-1318
-
-
Kantarjian, H.M.1
Cortes, J.E.2
Kim, D.W.3
Khoury, H.J.4
Brummendorf, T.H.5
Porkka, K.6
-
70
-
-
84906936161
-
-
Jabbour E., Kantarjian H. Chronic myeloid leukemia: 2012 update on diagnosis, monitoring, and management 2012, 87:1038-1045.
-
(2012)
Chronic myeloid leukemia: 2012 update on diagnosis, monitoring, and management
, vol.87
, pp. 1038-1045
-
-
Jabbour, E.1
Kantarjian, H.2
-
71
-
-
70249141675
-
Dasatinib in the treatment of chronic myeloid leukemia in accelerated phase after imatinib failure: the START-A trial
-
Apperley J.F., Cortes J.E., Kim D.W., Roy L., Roboz G., Bullorsky E.O., et al. Dasatinib in the treatment of chronic myeloid leukemia in accelerated phase after imatinib failure: the START-A trial. J Clin Oncol 2009, 27:3472-3479.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3472-3479
-
-
Apperley, J.F.1
Cortes, J.E.2
Kim, D.W.3
Roy, L.4
Roboz, G.5
Bullorsky, E.O.6
-
72
-
-
84862028031
-
Nilotinib in patients with Ph+ chronic myeloid leukemia in accelerated phase following imatinib resistance or intolerance: 24-month follow-up results
-
le Coutre P.D., Giles F.J., Hochhaus A., Apperley J.F., Ossenkoppele G.J., Blakesley R., et al. Nilotinib in patients with Ph+ chronic myeloid leukemia in accelerated phase following imatinib resistance or intolerance: 24-month follow-up results. Leukemia 2012, 26:1189-1194.
-
(2012)
Leukemia
, vol.26
, pp. 1189-1194
-
-
le Coutre, P.D.1
Giles, F.J.2
Hochhaus, A.3
Apperley, J.F.4
Ossenkoppele, G.J.5
Blakesley, R.6
-
73
-
-
84896405273
-
Tyrosine kinase inhibitors as initial therapy for patients with chronic myeloid leukemia in accelerated phase
-
Ohanian M., Kantarjian H.M., Quintas-Cardama A., Jabbour E., Abruzzo L., Verstovsek S., et al. Tyrosine kinase inhibitors as initial therapy for patients with chronic myeloid leukemia in accelerated phase. Clin Lymphoma Myeloma Leuk 2014, 14:155-162.
-
(2014)
Clin Lymphoma Myeloma Leuk
, vol.14
, pp. 155-162
-
-
Ohanian, M.1
Kantarjian, H.M.2
Quintas-Cardama, A.3
Jabbour, E.4
Abruzzo, L.5
Verstovsek, S.6
-
74
-
-
78049528573
-
Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2years: the prospective, multicenter Stop Imatinib (STIM) trial
-
Mahon F.X., Rea D., Guilhot J., Guilhot F., Huguet F., Nicolini F., et al. Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2years: the prospective, multicenter Stop Imatinib (STIM) trial. Lancet Oncol 2010, 11:1029-1035.
-
(2010)
Lancet Oncol
, vol.11
, pp. 1029-1035
-
-
Mahon, F.X.1
Rea, D.2
Guilhot, J.3
Guilhot, F.4
Huguet, F.5
Nicolini, F.6
-
75
-
-
84923081115
-
Long term follow-up after imatinib cessation for patients in deep molecular response: the updated results of the STIM1 study
-
Mahon F.X., Rea D., Guilhot J., Guilhot F., Huguet F., Nicolini F., et al. Long term follow-up after imatinib cessation for patients in deep molecular response: the updated results of the STIM1 study. Blood (ASH Annual Meeting Abstracts) 2013, 122:255.
-
(2013)
Blood (ASH Annual Meeting Abstracts)
, vol.122
, pp. 255
-
-
Mahon, F.X.1
Rea, D.2
Guilhot, J.3
Guilhot, F.4
Huguet, F.5
Nicolini, F.6
-
76
-
-
84886917643
-
Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study
-
Ross D.M., Branford S., Seymour J.F., Schwarer A.P., Arthur C., Yeung D.T., et al. Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study. Blood 2013, 122:515-522.
-
(2013)
Blood
, vol.122
, pp. 515-522
-
-
Ross, D.M.1
Branford, S.2
Seymour, J.F.3
Schwarer, A.P.4
Arthur, C.5
Yeung, D.T.6
-
77
-
-
84894050087
-
Preliminary report of the STIM2 study: a multicenter stop imatinib trial for chronic phase chronic myeloid leukemia de novo patients on imatinib
-
Mahon F.X., Nicolini F.E., Noel M.P., Escoffre M., Charbonnier A., Rea D., et al. Preliminary report of the STIM2 study: a multicenter stop imatinib trial for chronic phase chronic myeloid leukemia de novo patients on imatinib. Blood (ASH Annual Meeting Abstracts) 2013, 122:654.
-
(2013)
Blood (ASH Annual Meeting Abstracts)
, vol.122
, pp. 654
-
-
Mahon, F.X.1
Nicolini, F.E.2
Noel, M.P.3
Escoffre, M.4
Charbonnier, A.5
Rea, D.6
-
78
-
-
84897573995
-
Loss of major molecular response as a trigger for restarting tyrosine kinase inhibitor therapy in patients with chronic-phase chronic myelogenous leukemia who have stopped imatinib after durable undetectable disease
-
Rousselot P., Charbonnier A., Cony-Makhoul P., Agape P., Nicolini F.E., Varet B., et al. Loss of major molecular response as a trigger for restarting tyrosine kinase inhibitor therapy in patients with chronic-phase chronic myelogenous leukemia who have stopped imatinib after durable undetectable disease. J Clin Oncol 2014, 32:424-430.
-
(2014)
J Clin Oncol
, vol.32
, pp. 424-430
-
-
Rousselot, P.1
Charbonnier, A.2
Cony-Makhoul, P.3
Agape, P.4
Nicolini, F.E.5
Varet, B.6
-
79
-
-
84886914746
-
TWIST it but don't spin it
-
Apperley J.F. TWIST it but don't spin it. Blood 2013, 122:470-471.
-
(2013)
Blood
, vol.122
, pp. 470-471
-
-
Apperley, J.F.1
|