Antiviral activity of benzimidazole derivatives. III. Novel anti-CVB-5, anti-RSV and anti-Sb-1 agents

Bioorganic and Medicinal Chemistry

Volumn 22, Issue 17, 2014, Pages 4893-4909

  Tonelli, Michele ^a   Novelli, Federica ^a   Tasso, Bruno ^a   Vazzana, Iana ^a   Sparatore, Anna ^b   Boido, Vito ^a   Sparatore, Fabio ^a   La Colla, Paolo ^c   Sanna, Giuseppina ^c   Giliberti, Gabriele ^c   Busonera, Bernardetta ^c   Farci, Pamela ^c   Ibba, Cristina ^c   Loddo, Roberta ^c  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

Anti CVB 5; anti RSV, anti Sb 1 activity; Benzimidazole derivatives; RNA and DNA viruses

Indexed keywords

1 BUTYL 2 (4 METHOXYPHENYL) 5 TRIFLUOROMETHYLBENZIMIDAZOLE; 1 PHENYLBENZIMIDAZOLE; 1 [(2 DIMETHYLAMINO)ETHYL] 2 (4 METHOXYPHENYL) 5 TRIFLUOROMETHYLBENZIMIDAZOLE; 1 [(2 METHOXY)ETHYL] 2 (4 METHOXYPHENYL) 5 TRIFLUOROMETHYLBENZIMIDAZOLE; 1 [(3 DIETHYLAMINO)PROPYL] 2 (4 METHOXYPHENYL) 5 TRIFLUOROMETHYLBENZIMIDAZOLE; 2 (HEPT 3 EN 3 YL) 1H BENZIMIDAZOLE; 2 (TETRAHYDROPYRAN 2 YL) 5 TRIFLUOROMETHYL 1H BENZIMIDAZOLE; 2 (TETRAHYDROPYRAN 2 YL)BENZIMIDAZOLE; 2 TRIFLUOROMETHYLBENZIMIDAZOLE; 2 [(2,6 DIFLUORO)PHENYL] 1 [(OCTAHYDRO 2H QUINOLIZIN 1 YL)METHYL] 5 TRIFLUOROMETHYLBENZIMIDAZOLE; 2 [(4 AMINO)BENZYL] 5,6 DICHLORO 1H BENZIMIDAZOLE; 2 [3 (3,7 DIAZABICYCLO[3.3.1]NONAN 2 YL)PROPYL] 1H BENZIMIDAZOLE; 2 [4 (ACETYLAMINO)BENZYL] 1H BENZIMIDAZOLE; 2 [4 (AMINO)BENZYL] 5 TRIFLUOROMETHYL 1H BENZIMIDAZOLE; 2 [OCTAHYDRO 2H QUINOLIZIN 1 YL] 1 PHENYLBENZPHENYLBENZIMIDAZOLE; 2 [OCTAHYDRO 2H QUINOLIZIN 1 YL]BENZIMIDAZOLE; 4 (METHOXYPHENYL) 1 [OCTAHYDRO 2H QUINOLIZIN 1 YL] 5 TRIFLUOROMETHYLBENZIMIDAZOLE; 4 [3 (1H BENZIMIDAZOL 2 YL)PROPYL]DECAHYDRO 1H 1,5 METHANOPYRIDO[1,2 A] [1,5]DIAZOCINE; 4 [3 (5 CHLORO 1H BENZIMIDAZOL 2-YL)PROPYL]DECAHYDRO 1H 1,5 METHANOPYRIDO[1,2 A] [1,5] DIAZOCINE; 5 CHLORO 2 (TETRAHYDROPYRAN 2 YL) 1H BENZIMIDAZOLE; 5 CHLORO 2 [3 (3,7 DIAZABICYCLO[3.3.1]NONAN 2 YL)PROPYL] 1H BENZIMIDAZOLE; 5 CHLORO 2 [OCTAHYDRO 2H QUINOLIZIN 1 YL] BENZIMIDAZOLE; ANTIVIRUS AGENT; BENDAZOL DERIVATIVE; BENZIMIDAZOLE DERIVATIVE; DIBENZO[C,E]BENZIMIDAZO[1,2 A]AZEPINE; DIHYDROPYRIDO[30,20:4,5]IMIDAZO[1,2 A][1,4]BENZODIAZEPIN 5 ONE; NM 108; RIBAVIRIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; BENZIMIDAZOLE;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; BOVINE VIRAL DIARRHEA VIRUS; CONTROLLED STUDY; COXSACKIE VIRUS B; COXSACKIE VIRUS B5; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MEDIAN EFFECTIVE CONCENTRATION; NONHUMAN; PESTIVIRUS; PICORNAVIRUS; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SB 1 VIRUS; STRUCTURE ACTIVITY RELATION; VIRUS STRAIN; ANIMAL; BOVINAE; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; CHLOROCEBUS AETHIOPS; DOSE RESPONSE; DRUG EFFECTS; ENTEROVIRUS; HAMSTER; HUMAN RESPIRATORY SYNCYTIAL VIRUS; MICROBIAL SENSITIVITY TEST; POLIOMYELITIS VIRUS; SYNTHESIS; VERO CELL LINE; VIRUS REPLICATION;

BOVINE VIRAL DIARRHEA VIRUS 1; DNA VIRUSES; RICE STRIPE VIRUS;

ANIMALS; ANTIVIRAL AGENTS; BENZIMIDAZOLES; CATTLE; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTEROVIRUS; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; POLIOVIRUS; RESPIRATORY SYNCYTIAL VIRUSES; STRUCTURE-ACTIVITY RELATIONSHIP; VERO CELLS; VIRUS REPLICATION;

EID: 84906936330     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2014.06.043     Document Type: Article

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