메뉴 건너뛰기




Volumn 289, Issue 35, 2014, Pages 24180-24187

Binding of TPP1 protein to TIN2 protein is required for POT1a,b protein-mediated telomere protection

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; CHROMOSOMES; DNA;

EID: 84906871869     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.592592     Document Type: Article
Times cited : (34)

References (29)
  • 1
    • 46249125488 scopus 로고    scopus 로고
    • How shelterin protects mammalian telomeres
    • Palm, W., and de Lange, T. (2008) How shelterin protects mammalian telomeres. Annu. Rev. Genet. 42, 301-334
    • (2008) Annu. Rev. Genet. , vol.42 , pp. 301-334
    • Palm, W.1    De Lange, T.2
  • 2
    • 33846692105 scopus 로고    scopus 로고
    • TPP1 is a homologue of ciliate TEBP-β and interacts with POT1 to recruit telomerase
    • DOI 10.1038/nature05469, PII NATURE05469
    • Xin, H., Liu, D., Wan, M., Safari, A., Kim, H., Sun, W., O'Connor, M. S., and Songyang, Z. (2007) TPP1 is a homologue of ciliate TEBP-β and interacts with POT1 to recruit telomerase. Nature 445, 559-562 (Pubitemid 46197638)
    • (2007) Nature , vol.445 , Issue.7127 , pp. 559-562
    • Xin, H.1    Liu, D.2    Wan, M.3    Safari, A.4    Kim, H.5    Sun, W.6    O'Connor, M.S.7    Songyang, Z.8
  • 4
    • 70350001509 scopus 로고    scopus 로고
    • OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation
    • Wan, M., Qin, J., Songyang, Z., and Liu, D. (2009) OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation. J. Biol. Chem. 284, 26725-26731
    • (2009) J. Biol. Chem. , vol.284 , pp. 26725-26731
    • Wan, M.1    Qin, J.2    Songyang, Z.3    Liu, D.4
  • 5
    • 81355150876 scopus 로고    scopus 로고
    • Telomere protection by TPP1/POT1 requires tethering to TIN2
    • Takai, K. K., Kibe, T., Donigian, J. R., Frescas, D., and de Lange, T. (2011) Telomere protection by TPP1/POT1 requires tethering to TIN2. Mol. Cell 44, 647-659
    • (2011) Mol. Cell , vol.44 , pp. 647-659
    • Takai, K.K.1    Kibe, T.2    Donigian, J.R.3    Frescas, D.4    De Lange, T.5
  • 6
    • 75749092997 scopus 로고    scopus 로고
    • Telomere protection by TPP1 is mediated by POT1a and POT1b
    • Kibe, T., Osawa, G. A., Keegan, C. E., and de Lange, T. (2010) Telomere protection by TPP1 is mediated by POT1a and POT1b. Mol. Cell. Biol. 30, 1059-1066
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 1059-1066
    • Kibe, T.1    Osawa, G.A.2    Keegan, C.E.3    De Lange, T.4
  • 7
    • 33745685066 scopus 로고    scopus 로고
    • Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres
    • Hockemeyer, D., Daniels, J. P., Takai, H., and de Lange, T. (2006) Recent expansion of the telomeric complex in rodents: two distinct POT1 proteins protect mouse telomeres. Cell 126, 63-77
    • (2006) Cell , vol.126 , pp. 63-77
    • Hockemeyer, D.1    Daniels, J.P.2    Takai, H.3    De Lange, T.4
  • 8
    • 34548317418 scopus 로고    scopus 로고
    • Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1
    • DOI 10.1038/nature06065, PII NATURE06065
    • Denchi, E. L., and de Lange, T. (2007) Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. Nature 448, 1068-1071 (Pubitemid 47345583)
    • (2007) Nature , vol.448 , Issue.7157 , pp. 1068-1071
    • Denchi, E.L.1    De Lange, T.2
  • 9
    • 22144490491 scopus 로고    scopus 로고
    • DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion
    • DOI 10.1038/ncb1275
    • Celli, G. B., and de Lange, T. (2005) DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion. Nat. Cell Biol. 7, 712-718 (Pubitemid 40975753)
    • (2005) Nature Cell Biology , vol.7 , Issue.7 , pp. 712-718
    • Celli, G.B.1    De Lange, T.2
  • 10
    • 0032489012 scopus 로고    scopus 로고
    • TRF2 protects human telomeres from end-to-end fusions
    • DOI 10.1016/S0092-8674(00)80932-0
    • van Steensel, B., Smogorzewska, A., and de Lange, T. (1998) TRF2 protects human telomeres from end-to-end fusions. Cell 92, 401-413 (Pubitemid 28093017)
    • (1998) Cell , vol.92 , Issue.3 , pp. 401-413
    • Van Steensel, B.1    Smogorzewska, A.2    De Lange, T.3
  • 11
    • 34547900244 scopus 로고    scopus 로고
    • Telomere maintenance through spatial control of telomeric proteins
    • DOI 10.1128/MCB.00603-07
    • Chen, L. Y., Liu, D., and Songyang, Z. (2007) Telomere maintenance through spatial control of telomeric proteins. Mol. Cell. Biol. 27, 5898-5909 (Pubitemid 47257842)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.16 , pp. 5898-5909
    • Chen, L.-Y.1    Liu, D.2    Songyang, Z.3
  • 13
    • 84855486059 scopus 로고    scopus 로고
    • Dyskeratosis congenita as a disorder of telomere maintenance
    • Nelson, N. D., and Bertuch, A. A. (2012) Dyskeratosis congenita as a disorder of telomere maintenance. Mutat. Res. 730, 43-51
    • (2012) Mutat. Res. , vol.730 , pp. 43-51
    • Nelson, N.D.1    Bertuch, A.A.2
  • 14
    • 78650639126 scopus 로고    scopus 로고
    • The genetics and clinical manifestations of telomere biology disorders
    • Savage, S. A., and Bertuch, A. A. (2010) The genetics and clinical manifestations of telomere biology disorders. Genet. Med. 12, 753-764
    • (2010) Genet. Med. , vol.12 , pp. 753-764
    • Savage, S.A.1    Bertuch, A.A.2
  • 15
    • 84855861086 scopus 로고    scopus 로고
    • Telomere length measurement can distinguish pathogenic from non-pathogenic variants in the shelterin component, TIN2
    • Vulliamy, T., Beswick, R., Kirwan, M., Hossain, U., Walne, A., and Dokal, I. (2010) Telomere length measurement can distinguish pathogenic from non-pathogenic variants in the shelterin component, TIN2. Clin. Genet. 81, 634-643
    • (2010) Clin. Genet. , vol.81 , pp. 634-643
    • Vulliamy, T.1    Beswick, R.2    Kirwan, M.3    Hossain, U.4    Walne, A.5    Dokal, I.6
  • 16
    • 77958603527 scopus 로고    scopus 로고
    • A child with severe form of dyskeratosis congenita and TINF2 mutation of shelterin complex
    • Sarper, N., Zengin, E., and Kiliç, S. Ç. (2010) A child with severe form of dyskeratosis congenita and TINF2 mutation of shelterin complex. Pediatr. Blood Cancer 55, 1185-1186
    • (2010) Pediatr. Blood Cancer , vol.55 , pp. 1185-1186
    • Sarper, N.1    Zengin, E.2    Kiliç, S.Ç.3
  • 17
    • 55749094159 scopus 로고    scopus 로고
    • TINF2 mutations result in very short telomeres: Analysis of a large cohort of patients with dyskeratosis congenita and related bone marrow failure syndromes
    • Walne, A. J., Vulliamy, T., Beswick, R., Kirwan, M., and Dokal, I. (2008) TINF2 mutations result in very short telomeres: analysis of a large cohort of patients with dyskeratosis congenita and related bone marrow failure syndromes. Blood 112, 3594-3600
    • (2008) Blood , vol.112 , pp. 3594-3600
    • Walne, A.J.1    Vulliamy, T.2    Beswick, R.3    Kirwan, M.4    Dokal, I.5
  • 18
    • 84892723396 scopus 로고    scopus 로고
    • A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice
    • Frescas, D., and de Lange, T. (2014) A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice. Genes Dev. 28, 153-166
    • (2014) Genes Dev. , vol.28 , pp. 153-166
    • Frescas, D.1    De Lange, T.2
  • 19
    • 84895795314 scopus 로고    scopus 로고
    • TRF2-tethered TIN2 can mediate telomere protection by TPP1/POT1
    • Frescas, D., and de Lange, T. (2014) TRF2-tethered TIN2 can mediate telomere protection by TPP1/POT1. Mol. Cell. Biol. 34, 1349-1362
    • (2014) Mol. Cell. Biol. , vol.34 , pp. 1349-1362
    • Frescas, D.1    De Lange, T.2
  • 21
    • 2442511752 scopus 로고    scopus 로고
    • INK4a
    • DOI 10.1016/S1097-2765(04)00256-4, PII S1097276504002564
    • Herbig, U., Jobling, W. A., Chen, B. P., Chen, D. J., and Sedivy, J. M. (2004) Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol. Cell 14, 501-513 (Pubitemid 38648803)
    • (2004) Molecular Cell , vol.14 , Issue.4 , pp. 501-513
    • Herbig, U.1    Jobling, W.A.2    Chen, B.P.C.3    Chen, D.J.4    Sedivy, J.M.5
  • 22
    • 0038451396 scopus 로고    scopus 로고
    • POT1 as a terminal transducer of TRF1 telomere length control
    • DOI 10.1038/nature01688
    • Loayza, D., and de Lange, T. (2003) POT1 as a terminal transducer of TRF1 telomere length control. Nature 423, 1013-1018 (Pubitemid 36806919)
    • (2003) Nature , vol.423 , Issue.6943 , pp. 1013-1018
    • Loayza, D.1    De Lange, T.2
  • 23
    • 77950196212 scopus 로고    scopus 로고
    • Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal
    • Sfeir, A., Kabir, S., van Overbeek, M., Celli, G. B., and de Lange, T. (2010) Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal. Science 327, 1657-1661
    • (2010) Science , vol.327 , pp. 1657-1661
    • Sfeir, A.1    Kabir, S.2    Van Overbeek, M.3    Celli, G.B.4    De Lange, T.5
  • 25
    • 0042420304 scopus 로고    scopus 로고
    • DNA damage foci at dysfunctional telomeres
    • DOI 10.1016/S0960-9822(03)00542-6
    • Takai, H., Smogorzewska, A., and de Lange, T. (2003) DNA damage foci at dysfunctional telomeres. Curr. Biol. 13, 1549-1556 (Pubitemid 37078413)
    • (2003) Current Biology , vol.13 , Issue.17 , pp. 1549-1556
    • Takai, H.1    Smogorzewska, A.2    De Lange, T.3
  • 26
    • 58149467017 scopus 로고    scopus 로고
    • Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita
    • He, H., Wang, Y., Guo, X., Ramchandani, S., Ma, J., Shen, M. F., Garcia, D. A., Deng, Y., Multani, A. S., You, M. J., and Chang, S. (2009) Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita. Mol. Cell. Biol. 29, 229-240
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 229-240
    • He, H.1    Wang, Y.2    Guo, X.3    Ramchandani, S.4    Ma, J.5    Shen, M.F.6    Garcia, D.A.7    Deng, Y.8    Multani, A.S.9    You, M.J.10    Chang, S.11
  • 27
    • 46249089163 scopus 로고    scopus 로고
    • Engineered telomere degradation models dyskeratosis congenita
    • DOI 10.1101/gad.1679208
    • Hockemeyer, D., Palm, W., Wang, R. C., Couto, S. S., and de Lange, T. (2008) Engineered telomere degradation models dyskeratosis congenita. Genes Dev. 22, 1773-1785 (Pubitemid 351915502)
    • (2008) Genes and Development , vol.22 , Issue.13 , pp. 1773-1785
    • Hockemeyer, D.1    Palm, W.2    Wang, R.C.3    Couto, S.S.4    De Lange, T.5
  • 28
    • 84863622662 scopus 로고    scopus 로고
    • Telomeric 3′ overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST
    • Wu, P., Takai, H., and de Lange, T. (2012) Telomeric 3′ overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST. Cell 150, 39-52
    • (2012) Cell , vol.150 , pp. 39-52
    • Wu, P.1    Takai, H.2    De Lange, T.3
  • 29
    • 39749134753 scopus 로고    scopus 로고
    • A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins
    • DOI 10.1126/science.1151804
    • Chen, Y., Yang, Y., van Overbeek, M., Donigian, J. R., Baciu, P., de Lange, T., and Lei, M. (2008) A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins. Science 319, 1092-1096 (Pubitemid 351300791)
    • (2008) Science , vol.319 , Issue.5866 , pp. 1092-1096
    • Chen, Y.1    Yang, Y.2    Van Overbeek, M.3    Donigian, J.R.4    Baciu, P.5    De Lange, T.6    Lei, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.