Changes in the responsiveness of hypothalamic PK2 and PKR1 gene expression to fasting in developing male rats

International Journal of Developmental Neuroscience

Volumn 38, Issue , 2014, Pages 87-90

  Iwasa, Takeshi ^a   Matsuzaki, Toshiya ^a   Tungalagsuvd, Altankhuu ^a   Munkhzaya, Munkhsaikhan ^a   Kawami, Takako ^a   Yamasaki, Mikio ^a   Murakami, Masahiro ^b   Kato, Takeshi ^a   Kuwahara, Akira ^a   Yasui, Toshiyuki ^a   Irahara, Minoru ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b SHIKOKU MEDICAL CENTER FOR CHILDREN AND ADULTS   (Japan)

Author keywords

Food deprivation; Hypothalamus; Prokineticin 2; Prokineticin receptor

Indexed keywords

ENDOCRINE GLAND DERIVED VASCULAR ENDOTHELIAL GROWTH FACTOR; G PROTEIN COUPLED RECEPTOR; MESSENGER RNA; PROKINETICIN 2; PROKINETICIN RECEPTOR; UNCLASSIFIED DRUG; PEPTIDE; PROKINETICIN RECEPTOR 1;

AGE DISTRIBUTION; ANALYSIS OF VARIANCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENT; DIET RESTRICTION; FEMALE; GENE; GENE EXPRESSION; HYPOTHALAMUS; MALE; MALNUTRITION; NEWBORN PERIOD; NONHUMAN; NUTRITIONAL STATUS; PERINATAL PERIOD; PK2 GENE; PKR1 GENE; PRIORITY JOURNAL; RAT; SENSITIVITY ANALYSIS; SEX DIFFERENCE; FOOD INTAKE; MATURATION; POSTNATAL DEVELOPMENT;

RATTUS;

EID: 84906858331     PISSN: 07365748     EISSN: 1873474X     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2014.08.004     Document Type: Article

References (18)

1. Beale K., Gardiner J.V., Bewick G.A., Hostomska K., Patel N.A., Hussain S.S., Jayasena C.N., Ebling F.J., Jethwa P.H., Prosser H.M., Lattanzi R., Negri L., Ghatei M.A., Bloom S.R., Dhillo W.S. Peripheral administration of prokineticin 2 potently reduces food intake and body weight in mice via the brainstem. Br. J. Pharmacol. 2013, 168:403-410.
2. Cheng M.Y., Bullock C.M., Li C., Lee A.G., Bermak J.C., Belluzzi J., Weaver D.R., Leslie F.M., Zhou Q.Y. Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus. Nature 2002, 417:405-410.
3. Cheng M.Y., Bittman E.L., Hattar S., Zhou Q.Y. Regulation of prokineticin 2 expression by light and the circadian clock. BMC Neurosci. 2005, 6:17.
4. Cheng M.Y., Leslie F.M., Zhou Q.Y. Expression of prokineticins and their receptors in the adult mouse brain. J. Comp. Neurol. 2006, 498:796-809.
5. Gardiner J.V., Bataveljic A., Patel N.A., Bewick G.A., Roy D., Campbell D., Green-wood H.C., Murphy K.G., Hameed S., Jethwa P.H., Ebling F.J., Vickers S.P., Cheetham S., Ghatei M.A., Bloom S.R., Dhillo W.S. Prokineticin 2 is a hypothalamic neuropeptide that potently inhibits food intake. Diabetes 2010, 59:397-406.
6. Iwasa T., Matsuzaki T., Murakami M., Kinouchi R., Gereltsetseg G., Fujisawa S., Kuwahara A., Yasui T., Irahara M. Sensitivities of mRNA expression levels of Kiss1 and its receptor, Kiss1r, to nutritional status are changed during the developmental period in female rats. J. Endocrinol. 2010, 207:195-202.
7. Iwasa T., Matsuzaki T., Kinouchi R., Gereltsetseg G., Murakami M., Nakazawa H., Yasui T., Irahara M. Changes in the responsiveness of serum leptin and hypothalamic neuropeptide Y mRNA levels to food deprivation in developing rats. Int. J. Dev. Neurosci. 2011, 29:377-380.
8. Iwasa T., Matsuzaki T., Murakami M., Kinouchi R., Gereltsetseg G., Nakazawa H., Yamamoto S., Kuwahara A., Yasui T., Irahara M. Changes in responsiveness of appetite, leptin and hypothalamic IL-1β and TNF-α to lipopolysaccharide in developing rats. J. Neuroimmunol. 2011, 236:10-16.
9. Iwasa T., Matsuzaki T., Kinouchi R., Gereltsetseg G., Murakami M., Kuwahara A., Yasui T., Irahara M. Developmental changes in the responsiveness of hypothalamic ER alpha mRNA levels to food deprivation. Neuro. Endocrinol. Lett. 2013, 34:543-5648.
10. Iwasa T., Matsuzaki T., Munkhzaya M., Tungalagsuvd A., Kawami T., Murakami M., Yamasaki M., Kato T., Kuwahara A., Yasui T., Irahara M. Changes in the responsiveness of hypothalamic prokineticin 2 mRNA expression to food deprivation in developing female rats. Int. J. Dev. Neurosci. 2014, 34:76-78.
11. Iwasa T., Matsuzaki T., Munkhzaya M., Tungalagsuvd A., Kawami T., Murakami M., Yamasaki M., Kato T., Kuwahara A., Yasui T., Irahara M. Prenatal exposure to glucocorticoids affects body weight, serum leptin levels, and hypothalamic neuropeptide-Y expression in pre-pubertal female rat offspring. Int. J. Dev. Neurosci. 2014, 36C:1-4.
12. Iwasa T., Matsuzaki T., Munkhzaya M., Tungalagsuvd A., Kawami T., Murakami M., Yamasaki M., Kato T., Kuwahara A., Yasui T., Irahara M. Pre-pubertal serum leptin levels and sensitivity to central leptin injection of prenatally undernourished female rats. Int. J. Dev. Neurosci. 2014, 35:52-54.
13. Li M., Bullock C.M., Knauer D.J., Ehlert F.J., Zhou Q.Y. Identification of two prokineticin cDNAs: recombinant proteins potently contract gastrointestinal smooth muscle. Mol. Pharmacol. 2001, 59:692-698.
14. Lin D.C., Bullock C.M., Ehlert F.J., Chen J.L., Tian H., Zhou Q.Y. Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor. J. Biol. Chem. 2002, 277:19276-19280.
15. Masuda Y., Takatsu Y., Terao Y., Kumano S., Ishibashi Y., Suenaga M., Abe M., Fukusumi S., Watanabe T., Shintani Y., Yamada T., Hinuma S., Inatomi N., Ohtaki T., Onda H., Fujino M. Isolation and identification ofEG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors. Biochem. Biophys. Res. Commun. 2002, 293:396-402.
16. Matsumoto S., Yamazaki C., Masumoto K.H., Nagano M., Naito M., Soga T., Hiyama H., Matsumoto M., Takasaki J., Kamohara M., Matsuo A., Ishii H., Kobori M., Katoh M., Matsushime H., Furuichi K., Shigeyoshi Y. Abnormal development of the olfactory bulb and reproductive system inmice lacking prokineticin receptor PKR2. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:4140-4145.
17. Ng K.L., Li J.D., Cheng M.Y., Leslie F.M., Lee A.G., Zhou Q.Y. Dependence of olfactory bulb neurogenesis on prokineticin 2 signaling. Science 2005, 308:1923-1927.
18. Pitteloud N., Zhang C., Pignatelli D., Li J.D., Raivio T., Cole L.W., Plummer L., Jacobson-Dickman E.E., Mellon P.L., Zhou Q.Y., Crowley W.F. Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:17447-17452.