Respiratory Physiology: Central Neural Control of Respiratory Neurons and Motoneurons during Sleep

Principles and Practice of Sleep Medicine: Fifth Edition

Volumn , Issue , 2010, Pages 237-249

  Horner, Richard L ^a  

^a UNIVERSITY OF TORONTO   (Canada)

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[No Author keywords available]

Indexed keywords

EID: 84906843143     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-1-4160-6645-3.00021-9     Document Type: Chapter

References (50)

1. Duffin J Functional organization of respiratory neurones: a brief review of current questions and speculations. Exp Physiol 2004, 89:517-529.
2. Rekling JC, Feldman JL PreBotzinger complex and pacemaker neurons: hypothesized site and kernel for respiratory rhythm generation. Annu Rev Physiol 1998, 60:385-405.
3. Orem J, Kubin L Respiratory physiology: central neural control. Principles and practice of sleep medicine 2000, 205-220. Saunders, Philadelphia. 3rd ed. M.H. Kryger, T. Roth, W.C. Dement (Eds.).
4. Horner RL Motor control of the pharyngeal musculature and implications for the pathogenesis of obstructive sleep apnea. Sleep 1996, 19:827-853.
5. Smith JC, Ellenberger HH, Ballanyi K, et al. Pre-Botzinger complex: a brainstem region that may generate respiratory rhythm in mammals. Science 1991, 254:726-729.
6. Feldman JL, Del Negro CA Looking for inspiration: new perspectives on respiratory rhythm. Nat Rev Neurosci 2006, 7:232-241.
7. McCrimmon DR, Alheid GF On the opiate trail of respiratory depression. Am J Physiol Regul Integr Comp Physiol 2003, 285-R1274.
8. McKay LC, Janczewski WA, Feldman JL Sleep-disordered breathing after targeted ablation of preBotzinger complex neurons. Nat Neurosci 2005, 8:1142-1144.
9. Mitchell GS Back to the future: carbon dioxide chemoreceptors in the mammalian brain. Nat Neurosci 2004, 7:1288-1290.
10. Jones BE Basic mechanisms of sleep-wake states. Principles and practice of sleep medicine 2000, 134-154. Saunders, Philadelphia. 3rd ed. M.H. Kryger, T. Roth, W.C. Dement (Eds.).
11. McGinty D, Szymusiak R The sleep-wake switch: a neuronal alarm clock. Nat Med 2000, 6:510-511.
12. Saper CB, Scammell TE, Lu J Hypothalamic regulation of sleep and circadian rhythms. Nature 2005, 437:1257-1263.
13. Mendelson WB Hypnotics: basic mechanisms and pharmacology. Principles and practice of sleep medicine 2000, 407-413. Saunders, Philadelphia. 3rd ed. M.H. Kryger, T. Roth, W.C. Dement (Eds.).
14. McCrimmon DR, Mitchell GS, Dekin MS Glutamate, GABA, and serotonin in ventilatory control. Regulation of breathing 1995, 151-218. Dekker, New York. J.A. Dempsey, A.I. Pack (Eds.).
15. Robinson RW, Zwillich CW Medications, sleep and breathing. Principles and practice of sleep medicine 2000, 797-812. Saunders, Philadelphia. 3rd ed. M.H. Kryger, T. Roth, W.C. Dement (Eds.).
16. Horner RL Neuromodulation of hypoglossal motoneurons during sleep. Respir Physiol Neurobiol 2008, 164:179-196.
17. Kubin L, Davies RO, Pack L Control of upper airway motoneurons during REM sleep. News Physiol Sci 1998, 13:637-656.
18. Lydic R, Baghdoyan HA Sleep, anesthesiology, and the neurobiology of arousal state control. Anesthesiology 2005, 103:1268-1295.
19. Siegel JM Brainstem mechanisms generating REM sleep. Principles and practice of sleep medicine 2000, 112-133. Saunders, Philadelphia. 3rd ed. M.H. Kryger, T. Roth, W.C. Dement (Eds.).
20. Chase MH, Morales FR Control of motoneurons during sleep. Principles and practice of sleep medicine 2000, 155-168. Saunders, Philadelphia. 3rd ed. M.H. Kryger, T. Roth, W.C. Dement (Eds.).
21. Luppi PH, Gervasoni D, Verret L, et al. Paradoxical (REM) sleep genesis: the switch from an aminergic-cholinergic to a GABAergic-glutamatergic hypothesis. J Physiol Paris 2006, 100:271-283.
22. Fuller PM, Saper CB, Lu J The pontine REM switch: past and present. J Physiol 2007, 584:735-741.
23. Worsnop C, Kay A, Pierce R, et al. Activity of respiratory pump and upper airway muscles during sleep onset. J Appl Physiol 1998, 85:908-920.
24. Phillipson EA, Bowes G Control of breathing during sleep. Handbook of physiology, sect 3, the respiratory system, vol II, Control of breathing, part 2 1986, 649-689. American Physiological Society, Bethesda, Md. N.S. Cherniack, J.G. Widdicombe (Eds.).
25. Horner RL, Kozar LF, Kimoff RJ, et al. Effects of sleep on the tonic drive to respiratory muscle and the threshold for rhythm generation in the dog. J Physiol 1994, 474:525-537.
26. Orem J, Lovering AT, Dunin-Barkowski W, et al. Endogenous excitatory drive to the respiratory system in rapid eye movement sleep in cats. J Physiol 2000, 527:365-376.
27. Wiegand L, Zwillich CW, Wiegand D, et al. Changes in upper airway muscle activation and ventilation during phasic REM sleep in normal men. J Appl Physiol 1991, 71:488-497.
28. Orem J Central respiratory activity in rapid eye movement sleep: augmenting and late inspiratory cells. Sleep 1994, 17:665-673.
29. Bellingham MC, Berger AJ Presynaptic depression of excitatory synaptic inputs to rat hypoglossal motoneurons by muscarinic M2 receptors. J Neurophysiol 1996, 76:3758-3770.
30. Remmers JE, deGroot WJ, Sauerland EK, et al. Pathogenesis of upper airway occlusion during sleep. J Appl Physiol 1978, 44:931-938.
31. Duron B, Marlot D Intercostal and diaphragmatic electrical activity during wakefulness and sleep in normal unrestrained adult cats. Sleep 1980, 3:269-280.
32. Brooks PL, Peever JH Glycinergic and GABAA-mediated inhibition of somatic motoneurons does not mediate REM sleep motor atonia. J Neurosci 2008, 28:3535-3545.
33. Goldstein RS Hypoventilation: neuromuscular and chest wall disorders. Clin Chest Med 1992, 13:507-521.
34. Chan E, Steenland HW, Liu H, et al. Endogenous excitatory drive modulating respiratory muscle activity across sleep-wake states. Am J Respir Crit Care Med 2006, 174:1264-1273.
35. Fenik VB, Davies RO, Kubin L REM sleep-like atonia of hypoglossal (XII) motoneurons is caused by loss of noradrenergic and serotonergic inputs. Am J Respir Crit Care Med 2005, 172:1322-1330.
36. Fenik V, Marchenko V, Janssen P, et al. A5 cells are silenced when REM sleep-like signs are elicited by pontine carbachol. J Appl Physiol 2002, 93:1448-1456.
37. Li A, Nattie E Catecholamine neurones in rats modulate sleep, breathing, central chemoreception and breathing variability. J Physiol 2006, 570:385-396.
38. Steenland HW, Liu H, Horner RL Endogenous glutamatergic control of rhythmically active mammalian respiratory motoneurons in vivo. J Neurosci 2008, 28:6826-6835.
39. Burgess C, Lai D, Siegel J, et al. An endogenous glutamatergic drive onto somatic motoneurons contributes to the stereotypical pattern of muscle tone across the sleep-wake cycle. J Neurosci 2008, 28:4649-4660.
40. Smith IE, Quinnell TG Pharmacotherapies for obstructive sleep apnoea: where are we now?. Drugs 2004, 64:1385-1399.
41. Veasey SC Pharmacotherapies for obstructive sleep apnea: how close are we?. Curr Opin Pulm Med 2001, 7:399-403.
42. Zuperku EJ, McCrimmon DR Gain modulation of respiratory neurons. Respir Physiol Neurobiol 2002, 131:121-133.
43. Stradling JR, Kozar LF, Dark J, et al. Effect of acute diaphragm paralysis on ventilation in awake and sleeping dogs. Am Rev Respir Dis 1987, 136:633-637.
44. Bennett JR, Dunroy HM, Corfield DR, et al. Respiratory muscle activity during REM sleep in patients with diaphragm paralysis. Neurol 2004, 62:134-137.
45. Arnulf I, Similowski T, Salachas F, et al. Sleep disorders and diaphragmatic function in patients with amyotrophic lateral sclerosis. Am J Respir Crit Care Med 2000, 161:849-856.
46. Chase MH, Morales FR The control of motoneurons during sleep. Principles and practice of sleep medicine 1994, 163-175. Saunders, Philadelphia. 2nd ed. M.H. Kryger, T. Roth, W.C. Dement (Eds.).
47. Foutz AS, Boudinot E, Morin-Surun MP, et al. Excitability of "silent" respiratory neurons during sleep-waking states: an iontophoretic study in undrugged chronic cats. Brain Res 1987, 404:10-20.
48. Yumino D, Bradley TD Central sleep apnea and Cheyne-Stokes respiration. Pro Am Thorac Soc 2008, 5:226-236.
49. Xi L, Smith CA, Saupe KW, et al. Effects of rapid-eye-movement sleep on the apneic threshold in dogs. J Appl Physiol 1993, 75:1129-1139.
50. Orem J Neuronal mechanisms of respiration in REM sleep. Sleep 1980, 3:251-267.