Synthesis of novel core-shell structured dual-mesoporous silica nanospheres and their application for enhancing the dissolution rate of poorly water-soluble drugs

Materials Science and Engineering C

Volumn 44, Issue , 2014, Pages 262-267

  Wu, Chao ^a   Sun, Xiaohu ^b   Zhao, Zongzhe ^a   Zhao, Ying ^a   Hao, Yanna ^a   Liu, Ying ^a   Gao, Yu ^a  

^a JINZHOU MEDICAL UNIVERSITY   (China)

^b BOHAI UNIVERSITY   (China)

Author keywords

Core shell dual mesoporous silica nanosphere (DMSS); Poorly water soluble drugs; Simvastatin

Indexed keywords

DIFFERENTIAL SCANNING CALORIMETRY; DISSOLUTION; FOURIER TRANSFORM INFRARED SPECTROSCOPY; GAS ADSORPTION; NANOSPHERES; SCANNING ELECTRON MICROSCOPY; STYRENE; THERMOGRAVIMETRIC ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET SPECTROSCOPY; X RAY DIFFRACTION;

CETYLTRIMETHYLAMMONIUM BROMIDE; DRUG-LOADING EFFICIENCY; NITROGEN ADSORPTION; POORLY WATER-SOLUBLE DRUGS; POWDER X RAY DIFFRACTION; SILICA NANOSPHERES; SIMVASTATIN; SOLVENT EVAPORATION METHOD; CORE-SHELL; DISSOLUTION RATES;

SHELLS (STRUCTURES);

CETRIMIDE; NANOSPHERE; SILICON DIOXIDE; SIMVASTATIN; SOLVENT; WATER;

ADSORPTION; CHEMISTRY; DIFFERENTIAL SCANNING CALORIMETRY; INFRARED SPECTROSCOPY; PARTICLE SIZE; POROSITY; SCANNING ELECTRON MICROSCOPY; SOLUBILITY; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION;

ADSORPTION; CALORIMETRY, DIFFERENTIAL SCANNING; CETRIMONIUM COMPOUNDS; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOSPHERES; PARTICLE SIZE; POROSITY; SILICON DIOXIDE; SIMVASTATIN; SOLUBILITY; SOLVENTS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; WATER; X-RAY DIFFRACTION;

EID: 84906839150     PISSN: 09284931     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.msec.2014.08.040     Document Type: Article

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