Mesoporous carbon as a novel drug carrier of fenofibrate for enhancement of the dissolution and oral bioavailability

International Journal of Pharmaceutics

Volumn 452, Issue 1-2, 2013, Pages 382-389

  Niu, Xia ^a   Wan, Long ^a   Hou, Zhong ^b   Wang, Tianyi ^a   Sun, Changshan ^a   Sun, Jin ^a   Zhao, Peng ^a   Jiang, Tongying ^a   Wang, Siling ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b SHENYANG MEDICAL COLLEGE   (China)

Author keywords

Fenofibrate; In vitro dissolution; Mesoporous carbon; Oral bioavailability; Poorly soluble drug

Indexed keywords

CARBON; DRUG CARRIER; FENOFIBRATE; MESOPOROUS CARBON; NITROGEN; PHENOL DERIVATIVE; POLOXAMER; RESIN; SOLVENT; TETRAETHOXYSILANE; UNCLASSIFIED DRUG;

ADSORPTION; ANIMAL EXPERIMENT; ARTICLE; CHEMICAL PROCEDURES; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ADSORPTION; DRUG BIOAVAILABILITY; DRUG RELEASE; DRUG SOLUBILITY; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; INCIPIENT WETNESS IMPREGNATION; MALE; MELTING POINT; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; STOMACH IRRITATION; STOMACH MUCOSA; SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY; X RAY POWDER DIFFRACTION;

EID: 84884210969     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.05.016     Document Type: Article

References (43)

1. Ambrogi, V., Perioli, L., Marmottini, F., Giovagnoli, S., Esposito, M., Rossi, C., 2007. Improvement of dissolution rate of piroxicam by inclusion into MCM-41 mesoporous silicate. Eur. J. Pharm. Sci. 32, 216-222. (Pubitemid 47532714)
2. Cooper, S.M., Brett, A., Cruden, B.A., Meyyappan, M., 2004. Gas transport characteristics through a carbon nanotubule. Nano Lett. 4, 377-381. (Pubitemid 38292921)
3. Charnay, C., Bégu, S., Tourné-Péteilh, C., Nicole, L., Lerner, D.A., Devoisselle, J.M., 2004. Inclusion of ibuprofen in mesoporous templated silica: drug loading and release property. Eur. J. Pharm. Biopharm. 57, 533-540. (Pubitemid 38490572)
4. Cauda, V., Muhlstein, L., Onida, B., Bein, T., 2009. Tuning drug uptake and release rates through different morphologies and pore diameters of confined mesoporous silica. Microporous Mesoporous Mater 118, 435-443.
5. Chinese Pharmacopoeia, 2010. Part 2. Chinese Pharmacopoeia Commission, Beijing, p.456.
6. Fuertes, A.B., Lota, G., Centeno, T.A., Frackowiak, E., 2010. Templated mesoporous carbons for capacitor applications. Carbon 48, 1056-1063.
7. Hu, Y.C., Zhi, Z., Wang, T.Y., Jiang, H.T., Wang, S.L., 2011. Incorporation of indomethacin nanoparticles into 3-D ordered macroporous silica for enhanced dissolution and reduced gastric irritancy. Eur. J. Pharm. Biopharm. 79, 544-551.
8. 2 composites as an energy storage material. Carbon 47, 3346-3354.
9. 2 microspheres with high specific surface area of selective enrichment of phosphopeptides by mass spectrometric analysis. Microporous Mesoporous Mater. 15, 2197-2205.
10. Jia, Z.R., Lin, P., Xiang, Y., Wang, X.Q., Wang, J.C., Zhang, X., Zhang, Q., 2011. A novel nanomatrix system consisted of colloidal silica and pH-sensitive polymethylacrylate improves the oral bioavailability of fenofibrate. Eur. J. Pharm. Biopharm. 79, 126-134.
11. Kesisoglou, F., Panmai, S.Y., Wu, Y., 2007. Nanosizing-oral formulation development and biophar-macmaceutical evaluation. Adv. Drug Del. Rev 59, 631-644. (Pubitemid 47285408)
12. Lipinski, C.A., 2002. Poor aqueous solubility - an industry wide problem in drug discovery. Am. Pharm. Rev. 53, 82-85.
13. Lillo-Ródenas, M.A., Juan, J.J., Amorós, D.C., Solano, A.L., 2004. About reactions occurring during chemical activation with hydroxides. Carbon 42, 1371-1375.
14. Lee, J., Kim, J., Hyeon, T., 2006. Recent progress in the synthesis of porous carbon materials. Adv. Mater. 18, 2073-2094. (Pubitemid 44325296)
15. Liu, R.L., Shi, Y.F., Wan, Y., Meng, Y., Zhang, F.Q., Gu, D., Chen, Z.X., Tu, B., Zhao, D.Y., 2006. Triconstituent co-assembly to ordered mesostructured polymer-silica and carbon-silica nanocomposites and large-pore mesoporous carbons with high surface areas. J. Am. Ceram. Soc. 128, 11652-11662. (Pubitemid 44338857)
16. Liou, T.H., 2010. Development of mesoporous structure and high adsorption capacity of biomass-based activated carbon by phosphoric acid and zinc chloride activation. Chem. Eng. J. 158, 129-142.
17. Ming-Thau, S., Ching-Min, Y., Sokoloski, T.D., 1994. Characterization and dissolution of fenofibrate solid dispersion systems. Int. J. Pharm. 103, 137-146. (Pubitemid 24037045)
18. Meng, Y., Gu, D., Zhang, F.Q., Shi, Y.F., Yang, H.F., Li, Z., Yu, C.Z., Tu, B., Zhao, D.Y., 2005. Ordered mesoporous polymers and homologous carbon frameworks: amphiphilic surfactant templating and direct transformation. Angew. Chem. Int. Ed. 117, 7215-7221.
19. Mellaerts, R., Jasper, A.G.J., Michiel, V.S., Hong, C., Jan, V.H., Patrick, A., Guy, V.M., Johan, A.M., 2008. Physical state of poorly water soluble therapeutic molecules loaded into SBA-15 ordered mesoporous ailica carriers: a case study with Itraconazole and Ibuprofen. Langmuir 24, 8651-8659.
20. Sanganwar, G.P., Gupta, R.P., 2008. Dissolution-rate enhancement of fenofibrate by adsorption onto silica using supercritical carbon dioxide. Int. J. Pharm. 360, 213-218.
21. Speybroeck, M.V., Mellaerts, R., Mols, R., Tha, T.D., Martens, J.A., Humbeeck, J.V., Annaert, P., Mooter, G.V.D., Augustijns, P., 2010. Enhanced absorption of the poorly soluble drug fenofibrate by tuning its release rate from ordered mesoporous silica. Eur. J. Pharm. Sci. 41, 623-630.
22. Sun, Y., Webley, P.A., 2010. Preparation of activated carbons from corncob with large specific surface area by a variety of chemical activators and their application in gas storage. Chem. Eng. J. 162, 883-892.
23. Thomas, M.J.K., Slipper, I., Walunj, A., Jain, A., Favretto, M.E., Kallinteri, P., Douroumis, D., 2009. Inclusion of poorly soluble drugs in highly ordered mesoporous silica nanoparticles. Int. J. Pharm. 387, 272-277.
24. Vix-Guterl, C., Frackowiak, E., Jurewicz, K., Friebe, M., Parmentier, J., Béguin, F., 2005. Electro-chemical energy storage in ordered porous carbon materials. Carbon 43, 1293-1302. (Pubitemid 40423370)
25. Vinu, A., Miyahara, M., Ariga, K., 2005. Biomaterial immobilization in nanoporous carbon molecular sieves: influence of solution pH, pore volume, and pore diameter. J. Phys. Chem. B 109, 6436-6441. (Pubitemid 40496860)
26. Vasconcelos, T., Sarmento, B., Costa, P., 2007. Solid dispersions as strategy to improve oral bioavailability of poor water soluble drugs. Drug Discov. Today 12, 1068-1075. (Pubitemid 350186132)
27. Valle-Vigón, P., Marta-Sevilla, M., Antonio, B., Fuertes, A.B., 2010. Synthesis of uniform mesoporous carbon capsules by carbonization of organosilica nanospheres. Chem. Mater. 22, 2526-2533.
28. Wishart, D.S., Konx, C., Guo, A.C., Shrivastava, S., Hassanali, M., Stothard, P., Chang, Z., Woolsey, J., 2006. Drug bank: a comprehensive resource for in silicon drug discovery and exploration. Nucleic Acids Res. 1, D668-D672.
29. Walker, G.M., Weatherly, L.R., 2001. Adsorption of dyes from aqueous solution - the effect of adsorbent pore size distribution and dye aggregation. Chem. Eng. J. 83, 201-206. (Pubitemid 32704500)
30. Wu, Z.X., Webley, P.A., Zhao, D.Y., 2010. Comprehensive study of pore evolution, mesostructural stability, and simultaneous surface functionalization of ordered mesoporous carbon (FDU-15) by wet oxidation as a promising adsorbent. Langmuir 26, 10277-10286.
31. Wang, X.F., Liu, P., Tian, Y., 2011a. Ordered mesoporous carbons for ibuprofen drug loading and release behavior. Microporous Mesoporous Mater. 142, 334-340.
32. Wang, T.Y., Zou, M.J., Jiang, H.T., Ji, Z.S., Gao, P., Cheng, G., 2011b. Synthesis of a novel kind of carbon nanoparticle with large mesopores and macropores and its application as an oral vaccine adjuvant. Eur. J. Pharm. Sci. 44, 653-659.
33. Walcarius, A., 2012. Electrocatalysis, sensors and biosensors in analytical chemistry based on ordered mesoporous and macroporous carbon-modified electrodes. Trends Anal. Chem. 38, 79-97.
34. Xia, K.S., Gao, Q.M., Wu, C.D., Song, S.Q., Ruan, M., 2007. Activation, characterization and hydrogen storage properties of the mesoporous carbon CMK-3. Carbon 45, 1989-1996. (Pubitemid 47238066)
35. Xu, W.J., Riikonen, J., Lehto, V., 2012. Mesoporous systems for poorly soluble drugs. Int. J. Pharm., http://dx.doi.org/10.1016/j.bbr.2011.03.031.
36. You, C.P., Yan, X.W., Kong, J.L., Zhao, D.Y., Liu, B.H., 2008. Direct electrochemistry of myoglobin based on bicontinuous gyroidal mesoporous carbon matrix. Electrochem. Commun. 10, 1864-1867.
37. Zhuang, X., Wan, Y., Feng, C.M., Shen, Y., Zhao, D.Y., 2009. Highly efficient adsorption of bulky dye molecules in wastewater on ordered mesoporous carbons. Chem. Mater. 21, 706-716.
38. Zhou, J.H., He, J.P., Zhang, C.X., Wang, T., Sun, D., Di, Z.Y., Wang, D.J., 2010. Mesoporous carbon spheres with uniformly penetrating channels and their use as a supercapacitor electrode material. Mater. Charact. 61, 31-38.
39. Zhu, S.M., Chen, C.X., Chen, Z.X., Liu, X.Y., Li, Y., Shi, Y., Zhang, D., 2010. Thermoresponsive polymer-functionalized mesoporous carbon for controlled drug release. Mater. Chem. Phys. 126, 357-363.
40. Zhang, Y.Z., Zhang, J.H., Jiang, T.Y., Wang, S.L., 2011. Inclusion of the poorly water-soluble drug simvastatin in mesocellular foam nanoparticles: drug loading and release properties. Int. J. Pharm. 410, 118-124.
41. Zhai, Y.P., Dou, Y.Q., Liu, X.X., Park, S.S., Ha, C.S., Zhao, D.Y., 2011. Soft-template synthesis of ordered mesoporous carbon/nanoparticle nickel composites with a high surface area. Carbon 49, 545-555.
42. Zhao, P., Jiang, H.T., Jiang, T.Y., Zhi, Z.Z., Wu, C., Sun, C., Zhang, J.H., Wang, S.L., 2012a. Inclusion of celecoxib into fibrous ordered mesoporous carbon for enhanced oral bioavailability and reduced gastric irritancy. Eur. J. Pharm. Sci. 45, 639-647.
43. Zhao, P., Wang, L.H., Sun, C.S., Jiang, T.Y., Zhang, J.H., Zhang, Q., Sun, J., Deng, Y.H., Wang, S.L., 2012b. Uniform mesoporous carbon as a carrier for poorly water soluble drug and its cytotoxicity study. Eur. J. Pharm. Biopharm. 80, 535-543.