T cell receptor stimulation impairs IL-7 receptor signaling by inducing expression of the microRNA miR-17 to target Janus kinase 1

Science Signaling

Volumn 7, Issue 340, 2014, Pages

  Katz, Gil ^a,b   Pobezinsky, Leonid A ^a   Jeurling, Susanna ^a   Shinzawa, Miho ^a   Van Laethem, Francois ^a   Singer, Alfred ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 17 RECEPTOR ALPHA; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR; JANUS KINASE 1; JANUS KINASE 3; MICRORNA; MICRORNA 17; STAT5 PROTEIN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; JAK1 PROTEIN, MOUSE; LUCIFERASE; LYMPHOCYTE ANTIGEN RECEPTOR; MESSENGER RNA; MIRN17 MICRORNA, MOUSE;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SURFACE; ENZYME SYNTHESIS; GENE EXPRESSION; IMMUNOPRECIPITATION; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; RNA TRANSLATION; SIGNAL TRANSDUCTION; THYMOCYTE; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; BLOTTING, WESTERN; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; IMMUNOPRECIPITATION; JANUS KINASE 1; LUCIFERASES; MICE; MICRORNAS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, INTERLEUKIN-7; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84906828273     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2005221     Document Type: Article

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