Bahamaolide A from the marine-derived Streptomyces sp. CNQ343 inhibits isocitrate lyase in Candida albicans

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 17, 2014, Pages 4291-4293

  Lee, So Hyoung ^a   Moon, Kyuho ^b   Kim, Heegyu ^a   Shin, Jongheon ^b   Oh, Dong Chan ^b   Oh, Ki Bong ^a  

^a Seoul National University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Bahamaolide A; Candida albicans; Isocitrate lyase; Marine actinomycete; Streptomyces sp.

Indexed keywords

BAHAMAOLIDE A; ISOCITRATE LYASE; LACTONE; MESSENGER RNA; UNCLASSIFIED DRUG; ANTIFUNGAL AGENT; ENZYME INHIBITOR; MACROLIDE; POLYENE;

ARTICLE; BIOLOGICAL ACTIVITY; CANDIDA ALBICANS; CANDIDIASIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; DELETION MUTANT; DOSE RESPONSE; DRUG ISOLATION; DRUG PURIFICATION; ENZYME ACTIVITY; GENE EXPRESSION; GLUCONEOGENESIS; GLYCOLYSIS; IC 50; METABOLITE; NONHUMAN; NUTRIENT AVAILABILITY; OXIDATION; PHENOTYPE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; STREPTOMYCES; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CONFORMATION; DRUG EFFECTS; ENZYMOLOGY; ISOLATION AND PURIFICATION; METABOLISM; MICROBIAL SENSITIVITY TEST; STRUCTURE ACTIVITY RELATION;

CANDIDA ALBICANS; STREPTOMYCES SP.;

ANTIFUNGAL AGENTS; CANDIDA ALBICANS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ISOCITRATE LYASE; LACTONES; MACROLIDES; MICROBIAL SENSITIVITY TESTS; MOLECULAR CONFORMATION; POLYENES; STREPTOMYCES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84906794483     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.07.021     Document Type: Article

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